このPython入門講座では、プログラミング経験の未経験者・初心者を対象に、ブラウザからPythonを実行できるサービスGoogle Colaboratory(Colab)を使って、Pythonの基礎をチュートリアル形式で解説します。 Colab は、Googl

Nature Communications - Tissue clearing has revolutionised histology, but limited penetration of antibodies and stains into thick tissue segments is still a bottleneck. Here, the authors...

Nature Methods - Two mScarlet variants with high brightness and fast maturation times have been evolved. These variants behave favorably as fusion tags and Förster resonance energy transfer...

Despite the easier use of multiple tissue clearing techniques in recent years, poor access to adequate light-sheet fluorescence microscopy remains a major obstacle for biomedical end users. Here, we...

Nature Medicine - Organ-specific aging clocks for multiple brain and body systems show that the biological age of one organ system selectively influences the aging of multiple other systems via...

Summary: Acto3D, an open-source software, facilitates cost-effective, high-resolution 3D imaging of fluorescently labelled tissues, offering streamlined visualisation, detailed control, and minimised...

Nature Communications - Poor access to suitable light-sheet microscopes remains a big obstacle for many end-users in biomedical research. Here, the authors present descSPIM, a low-cost,...

Shared with Dropbox

脳神経・発生・がん分野で注目が集まり，透明化組織のまるごと観察やライブイメージングが可能な「ライトシート顕微鏡」の初の実験書が登場．サンプルの準備から，実際の撮影や発展的手法までを丁寧に解説した一冊．

理化学研究所発スタートアップのCUBICStars（福岡県久留米市）は創薬の前臨床試験でマウスの臓器を透過し、新薬の効果を分析するサービスを始める。特殊な薬剤で透明にし高精細に映し出す。全身の臓器の働きが一目で分かるようになる。副作用の効果も予測でき有望な新薬の開発期間の短縮につなげる。同社は理化学研究所の上田泰己チームリーダーが2019年に創業した。開発した技術は���マウスを特殊な溶液に漬け、

このPython入門講座では、プログラミング経験の未経験者・初心者を対象に、ブラウザからPythonを実行できるサービスGoogle Colaboratory(Colab)を使って、Pythonの基礎をチュートリアル形式で解説します。 Colab は、Googl

理研らの共同研究グループは、全臓器・全身スケールの3次元組織染色・観察技術「CUBIC-HistoVIsion（CUBIC-HV）」を確立した。

Nature Communications - Tissue clearing has revolutionised histology, but limited penetration of antibodies and stains into thick tissue segments is still a bottleneck. Here, the authors...

Listen and subscribe to the Science Podcast featuring the most interesting news and research from the Science family of journals.

Nature Communications - Tissue clearing has revolutionised histology, but limited penetration of antibodies and stains into thick tissue segments is still a bottleneck. Here, the authors...

Nature Communications - Tissue clearing has revolutionised histology, but limited penetration of antibodies and stains into thick tissue segments is still a bottleneck. Here, the authors...

Nature Aging - Sen et al. show that, during human cellular senescence and mouse tissue aging, chromatin alterations promote the initiation of transcription from non-canonical sites and lead to...

Nature Neuroscience - The authors developed a CUBIC tissue clearing and expansion method to generate an editable, point-based single-cell-resolution brain atlas. This atlas, termed CUBIC-Atlas, can...