Must tumor initiation always precede metastasis? Glad to write this
@NEJM
article spotlighting one of the most intriguing papers I have read recently
@Gilbertson_Lab
@e_rahrmann
Metastasis is considered a late event in tumor progression. Recent findings that nontransformed epithelial cells can disseminate and colonize distant organs have implications for therapy and regenerative medicine.
Delighted to share that I will be starting my lab
@sloan_kettering
SKI Molecular Pharmacology, supported by Medicine & CRC Center. We will use patient-derived models to study regenerative plasticity in metastasis, and are recruiting at all levels!
#MSKCC
#metastasis
#organoids
🚨
#BREAKING
: Cancer metastasis and wound healing have more in common than you might think. New research from SKI suggests that metastatic cells co-opt the body’s natural wound-healing abilities to spread.
@LabMassague
@KarunaMDPhD
@NatureCancer
Congratulations to Karuna Ganesh for being selected as the Metastasis Research Society Sue Eccles Early Career Investigator awardee for 2024! Karuna will be presenting at
#MRS2024
(), be sure not to miss it!
@KarunaMDPhD
Sad to be shutting down our lab a few short months after we opened. We’ll be working remotely and I will continue to care for our vulnerable cancer patients
@sloan_kettering
as we fight
#COVID19
I am so proud of my amazing young lab for handling 2020 with such grace and passion. Looking forward to the discoveries we will make together in 2021! Happy Holidays!
Delighted to share our new review on Metastasis-Initiating Cells and Ecosystems in the 10th anniversary edition of
@CD_AACR
with
@LabMassague
. Congratulations
@ElizSMcKenna
and Cancer Discovery team!
We are recruiting postdocs to join us in a dynamic and fun environment to study
#metastasis
using patient
#organoids
and mouse models - immunology background/interest particularly welcome. Please RT.
Taking exceptional care of our cancer patients is a team effort. So grateful to be able to thank this outstanding team for their hard work!
@MSKCancerCenter
@MSK_DeptOfMed
#STGI
MSK researchers are applying findings from single-cell technology and computational tools toward understanding and treating metastasis. At
#AACR24
,
@dana_peer
discussed results from three studies on how cellular plasticity drives cancer metastasis. More:
I was delighted to give a talk to the annual meeting of the Koch Institute
@kochinstitute
celebrating the 50 years of cancer biology at MIT. Thanks
@shaleklab
and Matthew for the kind invitation !
Congratulations to this year's class of Conquer Cancer Grant and Award recipients! We can't wait to celebrate with you at
#ASCO24
! Full list of recipients:
Andrea Schietinger, PhD, delivered the 2023 AACR-Irving Weinstein Foundation Distinguished Lecture at
#AACR23
. This award acknowledges her outstanding scientific contributions that have inspired creative thinking and new directions in
#cancerresearch
.
Honored to join this amazing group of physician scientists working to transform how we treat disease. Thank you
@BWFUND
and my mentors and colleagues
@LabMassague
@sloan_kettering
!
🚨Calling all High School Students: join us on Wed— Nov 18 at 6 PM(EST) to hear 3 of our researchers
@sloan_kettering
talk about their exciting science:
@KarunaMDPhD
@JustinPerryPhD
& Thomas Norman. The event will be hosted by MSK President & CEO: Dr. Craig Thompson. Register 👇
🏁And that's the end for
#THPT23
. We want to thank all the attendees, speakers, & sponsors for making this an unforgettable 2nd edition. We hope you enjoyed yourself, have a safe trip home, and look forward to seeing you at a future VIB Conference! 👋
#VIBConf
Zena Werb was a pioneer; a huge loss for science. In this interview she articulates the challenges women of her generation had to overcome, and the work yet to be done.
Feeling very privileged to get to spend a week with these inspiring scientists...Thanks to Cedric for putting this amazing retreat together
@CedricBlanpain
👇🏽👇🏽👇🏽 continually inspired by the amazing
#WomenInScience
in my lab, my mentors, friends and colleagues in the field and beyond who are pushing boundaries and doing phenomenal science.
Celebrating all
#WomenInScience
especially the incredible females in my lab and my mentors that have been by my side! Science is an amazing job and gender biases are improving every day but let’s not forget the dual standards many of us experience!
Feeling inspired after a fantastic day of science
@TheCrick
, presenting our work and meeting the amazing scientists here. Thank you for inviting me and
@bealelab
for hosting!
The microbiome is important in cancer, but we often don't know why and how. This elegant study from Thomas Meyer's group
@NatureMedicine
and
@Nature
@HansClevers
define one key mechanism of bacterial carcinogenesis.
Groundbreaking work by Ilaria Malanchi
@TheCrick
, Joo-Hyeon Lee
@SCICambridge
and colleagues: fluorescent labeling of metastatic niche cells enables precise characterization of the
#tumormicroenvironment
This week on the Nature cover: Cancer deconstructed. Fluorescent labelling reveals the changing cellular environment of early-state metastasis. Browse this issue here:
2 in 1! Congratulations to our wonderful
@TriIMDPhD
student
@Katie_Luckett_
on officially becoming a PhD candidate and publishing a review on organoid immune engineering this week! 👇🏽👇🏽👇🏽
Curious about how we can utilize
#Organoids
to study the role of the immune system in cancer? Check out my review "Engineering the Immune Microenvironment into Organoid Models" with
@KarunaMDPhD
, online this week!
Mounting evidence that metastasis stem cells are distinct from cancer stem cells - now with intravital microscopy from
@vanRheenen_Lab
@CellStemCell
Closing the lights of the
#RockIsland
after 3 amazing days of science and fun and food and spritz
#EMBOcancerEvo
#TMFOCE
Hope you all enjoyed this second edition The Many Faces of Cancer Evolution, it was a blast! Thank you and see you all in 2 years 😉
Watch Abhijit Banerjee, Esther Duflo and Michael Kremer receive their medals and diplomas at the
#NobelPrize
award ceremony today. Congratulations!
They were awarded the 2019 Prize in Economic Sciences “for their experimental approach to alleviating global poverty.”
The Molecular Pharmacology Program at Sloan Kettering Institute
@MSKCancerCenter
is hiring new faculty. If your research is related to cancer therapeutics, protein engineering, targeted protein degradation, or gene therapy please apply:
Congratulations to our spectacular collaborators
@dana_peer
,
@science_wallet
and
@russell_kunes
on Spectra - a much needed and powerful tool enabling discovery of gene programs from single cell data 👇🏽👇🏽👇🏽
1. Thrilled and proud to announce our latest preprint: Spectra -Supervised discovery of interpretable gene programs from single-cell data. It is a factorization method that really works and is already in intensive use across projects in my own lab -->
@NCIDirector
Increase R01 budgets (especially modular) to reflect real costs of doing science, decrease paperwork per grant application until JIT stage and remove mandatory budget cuts.
The Karuna Ganesh Lab
@KarunaMDPhD
@sloan_kettering
is looking for a Senior Research Technician to support the management of patient-derived tumor organoid collections
Apply 👉 or retweet!
To learn more 👇
"Aspirations aren’t enough — you need information to create the bridge to actual achievement." Information access is key to achieving DEI in academic medicine. My
@sloan_kettering
colleague's inspiring journey:
Lung cancer cells can function like "Catch Me If You Can," changing their driver gene mutations and identity to escape attack
@ScienceMagazine
@ScienceVisuals
🥳 Huge congrats to Anna Obenauf (
@obenaufa
) for being awarded an
#ERCCoG
! Her lab aims to unlock immunity in
#cancer
by investigating tumour evolution during therapy, with a focus on
#KRASi
therapy. (1/2)
Great keynote by John Dick
#tumour19
: what matters most for cancer relapse? Stemness — regardless of genotype, treatment etc. The challenge for the field is to understand how to effectively target stemness.
Last two years in Ganesh lab at MSKCC have been very enriching. I am grateful to have had this opportunity to work with such extraordinary people. Thank you
@KarunaMDPhD
,
@f_cambuli
,
@wgsmahmoud
,
@saskia_hartner
and other members of Ganesh Lab for everything. Until next time…
I’m excited to have finished my first year at
@WeillCornellGS
as a Pharmacology PhD student and joined
@KarunaMDPhD
’s lab at
@sloan_kettering
. While this year was especially challenging, we came out as more socially aware and engaged students and scientists.
Can the same metabolic enzyme both promote and restrain tumor progression? Check out my
@NatureNV
with
@lydfinley
highlighting new work in
@Nature
from the
@FendtLab
on how dynamic control of metabolism is essential for distinct stages of tumor progression
Congratulations
@AndreaCercek
Luis Diaz,
@LumishMelissa
and colleagues on this practice changing advance with neoadjuvant anti-PD1 blockade for dMMR rectal cancer.
Mismatch repair–deficient, locally advanced rectal cancer was highly sensitive to single-agent PD-1 blockade. Longer follow-up is needed to assess the duration of response.
#ASCO22
Honored and grateful for receiving a Minority Faculty Scholar Award from the AACR MICR Council. To know about our research on
#colorectal
cancer disparities, check out my talk at the
#AACR22
Cancer Health Disparities mini-symposium, today at 3:35pm CDT, Room 295 (abstract 3634).
🔴🔴Our paper is out today in
@CellCellPress
! Since the preprint and thanks to the reviewers, we added a validation series of 10,000+ patients, an analysis of the timing of metastases & linked different analyses to further extended the hypotheses