Yelena Y. Janjigian MD
@YJanjigianMD
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Chief, Gastrointestinal Oncology at Memorial Sloan Kettering Cancer Center
New York, NY
Joined September 2017
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Checkmate 649 published!
@sloan_kettering
✅
@KoheiShitara
#ASCO21
@ASCO
Leading Phase III studies is fun! Thank you to all the patients and caregivers, to my amazing colleagues and
@bmsnews
@ScienceAtBMS
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Checkmate 649 Two- year update published on line today in Nature. Open Access coming soon
@KoheiShitara
@Nature
@mvicaracal
@MSKCancerCenter
@MSK_DeptOfMed
@OncoAlert
8
70
304
I love seeing my work in the same issue with papers about quantum physics and volcanic ash! My family of ‘hard’ scientists finally impressed. I ❤️
@Nature
@mvicaracal
@MyriamChalabi
#Science
#cancer
25
11
286
Notes from a 7th grader’s science class! My daughter is learning about
#immunesystem
and
#Immunology
#WomenInSTEM
I am so proud.
#nyc
#doe
the future of science
@sloan_kettering
15
20
233
My mom called to inform me she discovered me on
@Twitter
-- studied every single tweet & response from others 'the whole night' with lots of feedback... PSA: my mama is watching your every move now...
16
2
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3 years from the phase II abstract
@OncoAlert
@ASCO
#GI19
to publication of interim Phase III. Thank you to collaborators
@KoheiShitara
@TaberneroJosep
&
@mvicaracal
@Nature
for easy pub process.
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Prodige24 adjuvant mFOLFIRINOX vs Gem in resected panc 5 year follow up. mFOLFIRINOX is better and completing all chemo survival is important. 5 year OS 43%
@myESMO
@OncoAlert
#ESMO2021
3
66
207
Excited to share the news!! Nivolumab FDA approved in 1st Line gastric cancer! Not restricted by CPS. Thankful to all our pts who participated in CM649.
@KoheiShitara
@sloan_kettering
@OncoAlert
4
50
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Celebrating with my amazing research team! We changed SOC again
@sloan_kettering
Twice in one month.
#gastriccancer
@RWilliams_MSK
@RyanMoyMDPhD
@FDAOncology
approval
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14
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Gastrointestinal Oncology Service
@sloan_kettering
is hiring. Are you passionate about translational research, clinical investigation and want to be on the team that brings hope and new treatments to cancer patients worldwide? Please DM me if interested and RT.
@OncoAlert
13
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183
Excited to finally share that Keynote 811 survival data in first line HER2+ gastroesophageal cancer will be presented at
@myESMO
@MSKCancerCenter
@MSK_DeptOfMed
4
46
184
Memorable night at
@ASCO
#asco22
10th annual Giants in Cancer Reception honoring the new inductees, including our own Luis Diaz
@MSKCancerCenter
who is being recognized in the Translational Science category. Thank you
@OncLive
@AndreaCercek
5
14
184
Congrats Charlie Rudin our new Cancer Center Deputy Director! So bright & kind. We met 15 yrs ago; I was 8 mos pregnant, doing my 1st talk
@asco
& looking for a job! Charlie was the discussant, his positivity & support settled my nerves & gave a needed
confidence boost
17
12
181
#woman
at a window. Manifesting for the next scientific meeting to be in
#italy
. Perhaps a pan tumor
#ERBB2
#HER2
@PTarantinoMD
@ScaltritiLab
@Daniela_Molena
@sandrapdangelo
15
0
173
My daughter made a diorama of Rosalind Franklin hidden behind a curtain while Wilkins, Watson & Crick get Noble Prize. Never too early to learn about discovery &scientific credit. Franklin’s contribution to the discovery of the double helix of 🧬 was crucial.She got a raw deal.
9
19
167
With super stars ⭐️⭐️ In
#NYC
@MSKCancerCenter
waking up to messages & congrats calls from all over 🌎 on how absolutely amazing our GI Oncology group is 🥰
@MSK_DeptOfMed
privileged to have
@ldiaz1971
@AndreaCercek
@LumishMelissa
as colleagues plus 43 gifted GI MDs.
#teamwork
Very proud of our study published in
@NEJM
. 100% clinical complete response with dostarlimab alone in mismatch repair-deficient locally advanced
#RectalCancer
. No radiation or surgery!
@ASCO
#ASCO22
@MSKCancerCenter
208
1K
5K
8
17
166
In TMB high tumors treated w/ ICB, improved OS was associated mainly with POLE muts and with defective DNA mismatch repair, not overall mutational burden.
@sloan_kettering
@BenjcRousseau
@MikeFooteMD
@ldiaz1
@OncoAlert
@SteveMaronMD
@CYOC_MSK
3
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Voted - 🇺🇸! Made time in between research meetings & right after I picked up oseltamivir at the pharmacy for kid
#2
who is home from school w influenza. Please
#vote
our future and freedom depends on it.
@MSKCancerCenter
@MSK_DeptOfMed
4
3
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To my colleague and gifted physician
@GABOUALFA
Happy 20 year service anniversary with Memorial Sloan-Kettering Cancer Center. Heres to many more discoveries and breakthroughs on GI Oncology service.
@sloan_kettering
8
8
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Our new CEO is a physician scientist and a pancreatic cancer surgeon. MSK is constantly evolving. I am thrilled for our patients and our scientific community
@MSKCancerCenter
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10
155
Excellent argument against preop chemo for MSI-H localized gastric cancer by
@LizzySmyth1
. “We can cure many MSI H gastric ca w surgery alone.”
@IGCCHouston
@MansfieldPaul
@ILSONDavid
@FlorianLordick
3
31
154
Exploring the beautiful Saint-Émilion region with my love❤️❤️Little R&R after a busy
@myESMO
#ESMO22
.
@janjim01
🌤☀️🌞l'équilibre travail-vie
#worklifebalance
7
2
151
I got to spend the week with this excellent team of residents rounding
@sloan_kettering
. Up next they get to round with DOM Chair. Thank you for covering the service this weekend Deb Schrag
@debschrag
.
@MSK_MedChiefs
@MSKEducation
2
6
143
Practice changing study by
@MSKCancerCenter
@MSK_DeptOfMed
Chair
@debschrag
& colleagues.
@OncoAlert
4
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136
Many improvements in
#gastric
cancer therapies from 2017 to 2023. Great to be back in Japan 🇯🇵 with
@KoheiShitara
at Japanese Society of Medical Oncology meeting. Looking forward to many more years of productive collaborations between our groups.
@MSKCancerCenter
3
7
138
MSK’s own Luis Diaz, MD will be
#POTUS
right hand man on the cancer advisory board!
@sloan_kettering
@LDiaz1
@OncoAlert
Expect strong leadership and innovation. President Biden Appoints Members to National Cancer Advisory Board
0
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$BMY announces positive Phase 3 trial results in first-line gastric and esophageal
#cancers
6
31
131
Google reminded me what life was like 2 years ago.
@ASCO
40k attendees- crowded halls. Glad I have pics to back up my old lady stories of the pre pandemic(s) scientific meetings to the generations trained in virtual space. “When I was your age...” Surreal.
4
3
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How do we Target
#KRAS
in Colorectal Cancer? Read this piece in
@nejm
& learn from one of
@MSKCancerCenter
brightest physician-scientists
@RonaYaeger
3
23
126
We have a two year position for early career investigator focused on gastroesophageal cancer.
Details below
1
29
121
The sheer joy on these faces! Picture taken the day we heard the great news from
@ConquerCancerFd
@MSKCancerCenter
that
@LumishMelissa
got a YIA &
@SteveMaronMD
a CDA.
#ASCO22
. Being a mentor is the best job I have!
8
2
123
#ESMO23
❤️Perfect for us!
@myESMO
@sara_lonardi1
@MyriamChalabi
@ChiaraCrem1
@JenSeligmann
@FilippoPietran4
3
20
114
Dr. Balogun
@FiyinfoluB
congratulations 🎈🎊🎉 on your well deserved Award for Patient Recognition. Your patients adore& respect you and your GI Oncology family is so proud of you!
@MSK_DeptOfMed
@MSKCancerCenter
@ILSONDavid
@ldiaz1971
@AndreaCercek
6
13
117
The next chapter in
#her2positive
EG cancer. The RP2D dose T-DXd 6.4 mg/kg + Cap 1000 mg/m2 BID. 43% ORR in Chemo and traz refractory disease. Up next 1st line TDXd/cape/pembro
@ASCO
@OncoAlert
@JeeyunM
@sloan_kettering
@YJanjigianMD
1
27
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Speaking about clinical trial development in my native language
#russian
@ASCO
,
#Russian
Society of Clinical Oncology (RUSSCO) & RakFond -as faculty at the RakFond-ASCO Clinical Trial Workshop for Young Investigators in Moscow, Russia. I am a bit nervous!
@sloan_kettering
7
4
116
Congratulations 🎈 Steve! Dave was my CDA mentor and I am yours. That makes Dave Solit your mentoring grandfather. Make us proud.
@SteveMaronMD
@DSolit
@ConquerCancerFd
@MSKCancerCenter
@MSK_DeptOfMed
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4
9
113
In pts w endometrial ca (dMMR & pMMR) pembrolizumab +chemotherapy resulted in significantly longer PFS than with chemotherapy alone 74% vs 38% progression free @ 12 mos. Congrats Dr. Carol Aghajanian & team!
2
13
108
Very cool paper and important reminder that we can learn a lot from well designed correlates of a ‘negative’ clinical trial.
@Nature
2
17
109
Esophageal and Gastric
@NCCN
guideline includes use of PD-1 inhibitor first line metastatic, CPS>5 and HER2 negative
@OncoAlert
5
28
106
Dinner conversation w my 13 year old daughter. Mama, which is the most powerful white blood cell?
#medtwitter
how would you answer?
#Immunology
42
8
103
I enjoyed meeting Japan’s brightest early career investigators at
#jsmo2023
and giving my feedback on work in progress and shared challenges in the quickly evolving field of
#gastric
cancer research.
@MSK_DeptOfMed
4
4
104
Endometria ca:The median OS ⬆️ with lenvatinib+ pembro than with chemo (pMMR: 17.4 vs. 12 mos; HR for death, 0.68; 95% CI, 0.56 to 0.84; P<0.001; overall: 18.3 vs. 11.4 mos; HR, 0.62; 95% CI, 0.51 to 0.75; P<0.001).
@NEJM
@sloan_kettering
1
29
103
An unforgettable experience to return to Paris after the challenges of the past 2 years. Thank you
@myESMO
#esmo2021
Now
#ESMO21
: Results of the CheckMate-649 study of Nivolumab + Ipilimumab or Chemotherapy vs. Chemotherapy alone in advanced gastric and esophageal cancer!!
@myESMO
@OncoAlert
@YJanjigianMD
@sloan_kettering
0
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The future is bright for
#HER2
gastric ca pts.
@LumishMelissa
used 89Zr-trastuzumab PET to identify HER2 heterogeneity in gastric ca pts. Innovative work
@sloan_kettering
recognized by
#ASCO21
Merit Award 🥇
@OncoAlert
@LewisLabMSKCC
@ConquerCancerFd
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@MSKCancerCenter
changed the paradigm in
#MSI
-H
#rectal
CA
@MSK_DeptOfMed
@AndreaCercek
presenting 12 mos update of
@NEJM
data @ plenary w Dr. Baba. With 💯😉 enthusiasm from the audience. 👏🇯🇵🇺🇸🌸🌸🌸
@ASCO
0
10
98
Mira que guapas (majas dicen acá en España) y felices 😁 —the best part of academic medicine is making friends and learning new languages.
#WCGIC2022
.
8
2
96
Two days of intense focus on gastric cancer w/added bonus of spending time with my friend Dr. Vivian Strong
@IGCCHouston
@MansfieldPaul
@MSKCancerCenter
Photo credit to Sr. Murray Brennan (a famous photographer)
2
7
97
Happy Holidays from our work family
@sloan_kettering
@MSK_DeptOfMed
to yours.
#GIOncology
@SteveMaronMD
@ImaneDika
@MikeFooteMD
@debschrag
@MSK_GeriOnc
@KarunaMDPhD
Share your pics- how are you keeping your team together?
3
5
96
Proud of my love ❤️. A compassionate physician, superb educator& role model to
@nyugrossman
colleagues. Expert in Point of Care Ultrasound
#POCUS
honored today by his colleagues with this prestigious award.
@BellevueHosp
patients so fortunate to have your care
4
3
94
The brilliant
@KarunaMDPhD
of
@MSKCancerCenter
@MSK_DeptOfMed
sharing her work using
#CRC
organoid models to discover new treatments to stop 🛑 tumor metastasis.
#SU2C
@SU2C
4
4
92
20 (69%, 95% CI 49–85) of 29 patients had an objective response
7
30
90
Congratulations Dr. Abou-Alfa
@GABOUALFA
. Adding yet another ⭐️FDA ⭐️approval to the long list of your accomplishments. Your dedication to your patients and the mission of
@MSKCancerCenter
@MSK_DeptOfMed
is exceptional. 👏👏👏
@OncoAlert
The FDA has approved a combination of
#immunotherapy
drugs (durvalumab plus the experimental drug tremelimumab) for people with unresectable liver cancer — based on a clinical led by MSK gastrointestinal medical oncologist Ghassan Abou-Alfa.
0
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4
13
91
Targeting the "undruggable" targets in colorectal cancer
#KRASG12C
#CRC
@MSKCancerCenter
@MSK_DeptOfMed
@RonaYaeger
&
@KlempnerSam
@FDAOncology
@OncoAlert
0
17
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He did! First day as an attending under his belt. Congratulations
@Sam_Cytryn
! It gets easier after today 😉
@MSKCancerCenter
@MSK_DeptOfMed
looking forward to opening more GEC studies in
#Westchester
.
5
6
89
Congrats
@RyanMoyMDPhD
-4 yrs of fellowship flew by
@sloan_kettering
. So productive ⭐️⭐️⭐️ K08🙌 and many papers -I am proud of the medical oncologist you’ve become.
@columbiacancer
is lucky to get you.
@SohailTavazoie
3
3
86
Important interview
@nytimes
with Dr. Mendelsohn, co-Director of
@sloan_kettering
Center for Young Onset Colorectal Cancer
@manjuggm
@CYOC_MSK
0
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I am riding
@Cycle4Survival
on May 13 2022
@MSKCancerCenter
to raise funds for analysis of microbiome/tumor/blood samples from esophagus & stomach cancer pts who developed cancer at a young age. Please support our team
#STGI
!
1
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1
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Promising Phase 2 data from Fight study in FGFR2 IHC+ GC. Pts w/ IHC 2-3+ 10% over expression w/ greater benefit. looking forward to seeing additional biomarker data including ctDNA and tumor NGS and need Phase III confirmation.
@OncoAlert
1
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Expresso and croissant with
@DocCatenacci
@myESMO
#ESMO2021
what can be more nourishing before the plenary this afternoon?
0
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Our mission
@MSKCancerCenter
is to end cancer for life. Making sure oncologists are aware of our exciting new breakthroughs is critical to improving outcomes for gastric and esophageal cancer patients.
Join us now for the next session at today's
#OncologyCongress
! Yelena Janjigian, MD (
@YJanjigianMD
) of
@MSKCancerCenter
is covering the evolving treatment landscape for gastric & GEJ cancers:
#gastriccancer
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82
Prevalence of Germline Alterations on Targeted Tumor-Normal Sequencing of EG Cancer | Esophageal Cancer
@JAMANetworkOpen
@sloan_kettering
The study supports germline testing in patients with gastric cancer and early-onset EG cancer.
0
29
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On my way to
#TimesSquare
. To do my talk in
#Immunotherapy
in GI tumors. Lots to cover!
@gotoPER
@donnashort
@DrChoueiri
@CharuAggarwalMD
Looking forward to this conference with practical tips on application of IO in clinic and management of tough clinical cases! Still not too late to join!
@DrChoueiri
@MattGalsky
@RobertFerrisMD
@YJanjigianMD
Drs. Sznol, Weber and Emens!
#GoToICIC
#gotoPER
@donnashort
0
3
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1
1
81
Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer
@NEJM
@ASCO
@KoheiShitara
2
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@KoheiShitara
visit to
@sloan_kettering
2 years ago. The world 🌎 felt so small and well connected. Collaborations and ideas came so naturally—including a positive global Phase 3 CM649 study. These friendships and global connections are key!
1
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In Destiny-Gastric03TDxd+5FU/pembro study 85% HER2+ tumors are also PDL1+ -further confirming the importance of dual anti PD1/HER2 blockade. Notably 20% of tumors tested HER2+ at local hospital were HER2- centrally-- highlighting the
#EGcancer
heterogeneity.
@OncoAlert
In this video,
@YJanjigianMD
,
@MSKCancerCenter
, discusses findings from a preliminary biomarker analysis of the ongoing DESTINY-Gastric03 trial.
@ESMOWorldGI
@myESMO
#WCGIC2022
Watch the video:
0
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4
21
78
The 13th Annual meeting of the Chinese GI OncologyGroup(CGOG). Wonderful to be back in beautiful Beijing to build collaborations with bright minds from all over China. Touring Peking university cancer hospital today!
@MSKCancerCenter
@MSK_DeptOfMed
0
4
78
No benefit w/ Avelumab Maintainence strategy in 1st line
#gasticcancer
. The OS curves cross at 9 mos. almost identical to 1st Pembro data.
@ASCO
#GI20
@OncoAlert
2
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1
1
75
The spirits are high at work today
@MSKCancerCenter
@MSK_DeptOfMed
Team
#STGI
will ride today to raise funds for
@Cycle4Survival
rare cancers! Come cheer us on tonight
@Equinox
on 61st!
@CowzerDarren
@ImaneDika
@MikeFooteMD
@lori_janjigian
0
3
71
Another night of hugs and awards. This time focusing on the future of our mentees!
@Sam_Cytryn
@MSK_DeptOfMed
@ConquerCancerFd
@ASCO
@MSKCancerCenter
@DSG_MD
YIAs and IDEA mentees.
Many many congratulations-
@ferguskeane2
@YJanjigianMD
(Chief & mentor)
@DrSamuelCytryn
- very talented MSK oncology Fellows - Conquer Cancer Young Investigator and Merit awards!
@MSK_DeptOfMed
@MSKCancerCenter
@CentralParkWMD
5
12
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1
6
71
Thank you
@NYCHealthSystem
@BellevueHosp
for vaccinating my girls! Feeling relieved and proud. My daughters felt strongly about getting vaccinated ASAP and asked me &
@janjim01
to take them.
#bellevuestrong
#Vaccine
#covid19
1
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4
3
70
~7% EG adeno are EGFR amplified. Difficult subset to study b/c EGFR MABs flopped in unselected Phase IIIs. Dr. Maron & team showed clinical benefit with EGFR inhibition in pts w/ EGFR amp EG ca.
@SteveMaronMD
@JCO_ASCO
@MSKCancerCenter
@MSK_DeptOfMed
1
18
70
On my way to Debbie’s Dream Foundation 10th Annual Gala to accept the 2019 Tree of Life Medical Award! I am honored and humbled by the work that is being done by the Foundation to help pts, raise awareness and funds to
#stopcancer
#stomachcancer
@StomachCancer_
@sloan_kettering
On May 4, 2019, Debbie's Dream Foundation will celebrate a decade of supporting patients, caregivers, and families and raising awareness and funds for stomach cancer research at our 10th Annual Dream Makers Gala. Come...
0
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Thrilled to support & celebrate the 2024
@ASCO
@ConquerCancerFd
YIA and IDEA awardees in GI onc! Honored to work with these talented physician-scientists
@MSKCancerCenter
Creating a supportive environment for them to thrive is what it's all about.
#ASCO24
#GIOncology
3
4
70
Thank you
@sloan_kettering
GI oncology advanced practice providers 💜❤️💜 National
#APP
week!
0
5
68
Spending quality time
@AACR
#AACR22
#nola
with the newest faculty joining
@MSKCancerCenter
@MSK_DeptOfMed
GI Oncology group! Welcome to the
#STGI
family.
@MikeFooteMD
@BenjcRousseau
. The future is bright ⭐️⭐️⭐️⭐️
1
6
67
Today’s Spotlight on
@sloan_kettering
#PancreaticCancer
dream team. Dr. Balogun
@FiyinfoluB
and the superb care coordinator Afua Awuah. Extra ⭐️⭐️⭐️ for the stylish attire.
#Wednesdayvibe
1
3
69
A breakthrough for esophagus and stomach cancer patients Top 5 of
#Science
advances by
@sloan_kettering
in 2021
#WomenInSTEM
@ECActionNetwork
@DeGregorioFF
@NoStomach4Cancr
@StomachCancer_
3
13
69
Zanidatamab (ZW25) monotherapy, & in combo w/ taxol or 5fu based therapy in HER2+ GC. 33% ORR monotherapy is promising! Watch out for diarrhea, it's been an issue IMO. Love ❤️ the renaissance of
#ERBB2
gastric cancer field. The more options the better for our pts.
@OncoAlert
0
20
69
Congrats Dr. Makker
@sloan_kettering
Well done 🤩 pembrolizumab+ lenvatinib Significantly Improved PFS and OS vs. Chemotherapy in Patients With Advanced Endometrial Cancer Following Prior Platinum-Based Chemotherapy in Phase 3 Study
0
11
67
Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation. Congratulations
@RielyMD
and many others
@MSKCancerCenter
@MSK_DeptOfMed
Looking forward to publication of
#CRC
data
@RonaYaeger
0
14
65
Check out our recent commentary in
@Cancer_Cell
@wolchokj
@sloan_kettering
@CharlotteAriyan
Eradicating micrometastases with immunecheckpoint blockade: Strike while the iron is hot
1
16
67
With the
#pianorecital
behind me I can finally focus on my
@ASCO
#GI20
talk! Biomarkers to Guide Surveillance and Adjuvant Therapy of Early-Stage Disease. See u in SF
@Daniela_Molena
@KlempnerSam
My piano teacher today: ‘ah...I can see that you submitted your grant’.
R01 is in! The off target effect of scientific research. Get out of your comfort zone.
#metronome
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Excited to have HER2 PET trial completed and published. Preclinical work began a decade ago with
@LewisLabMSKCC
& supported by
@DeptofDefense
&
@ConquerCancerFd
Kudos to
@LumishMelissa
@SteveMaronMD
organizing & publishing this story.
@MSKCancerCenter
@MSK_DeptOfMed
Our latest.. lead by
@YJanjigianMD
... Noninvasive Assessment of Human Epidermal Growth Factor Receptor 2 (HER2) in Esophagogastric Cancer Using 89Zr-Trastuzumab PET: A Pilot Study
0
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2
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So nice to share the podium at
#ASCO24
with my colleague and friend
@VickyMakker
. Feels like just yesterday we were fellows together!
@MSK_DeptOfMed
@MSKCancerCenter
1
6
64
#California
dreaming ☀️☀️☀️about the next steps with upcoming projects & collaborations. Thankful for the opportunity to do this with
@SU2C
#SU2C
@MSKCancerCenter
@MSK_DeptOfMed
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@MSKCancerCenter
we use PDL-1 PET to help direct next generation of immunotherapy clinical trials in gastroesophageal cancer to help more patients. Great paper by
@Sam_Cytryn
in collaboration w/ Lewis lab
@LewisLabMSKCC
@MSK_DeptOfMed
Can we measure programmed-death ligand 1 status in gastroesophageal cancer with PET?
#NuclearMedicine
#GastricAdenocarcinoma
#PETscan
@MSKCancerCenter
@Sam_Cytryn
@YJanjigianMD
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#NursesWeek
#NursesDay2020
#ThankYouNurses
@sloan_kettering
#Throwback
to pre
#COVID19
. we ❤️❤️❤️❤️ our nurses. Their strength, professionalism and expertise continue to inspire!
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Come to NYC on January 26 and join our
@MSKCancerCenter
@MSK_DeptOfMed
GI Oncology crew in a LIVE session with FREE registration. All star line up
@EileenMOReilly
@GABOUALFA
@MikeFooteMD
and more!
@OncLiveSOSS
@OncLive
@donnashort
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In Japan Phase 2 DESTINY-Gastric01 Trial of DS-8201 Versus Chemotherapy Met Primary Endpoint!!!⭐️⭐️⭐️
Biggest deal in HER2+
#gastriccancer
. US study is on the way
@sloan_kettering
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Mission accomplished!! Memorable night with
@MSKCancerCenter
@Cycle4Survival
riding together for a common cause. Thank you to all the riders and supporters ❤️
@RyanMoyMDPhD
@SteveMaronMD
@ImaneDika
@W_Park_MD
@MikeFooteMD
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Great experience working with
@TheLancet
team and my colleagues
@KoheiShitara
@BMS_ImmunOnc_US
publishing this data
@OncoAlert
@sloan_kettering
#Nivolumab
plus chemotherapy shows superior OS, PFS benefit, and acceptable safety profile—compared to chemotherapy alone—in previously untreated advanced gastric, gastro-oesophageal junction, or oesophageal adenocarcinoma.
🔗 , by
@YJanjigianMD
et al.
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Exciting early data in 11 pts 61% ORR in heavily pretreated gastric cancer w claudin 18.2 CAR-T CT041. Over half of claudin 18.2 expression high are in non -signet ring tumors. No grade 5 events. Is PFS 5.6 mos really worth the trouble -hope we can do better in earlier lines?
Chanel 4
@myESMO
#ESMO21
@LizzySmyth1
chairing Upper GI Oral session tune in to check out Claudin 18.2
@CARsgen_Ther
Car-T data in gastric cancer.
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@MSKCancerCenter
@MSK_DeptOfMed
We are hiring a physician scientist w/ focus in GI Oncology.We value academic rigor, innovation, & patient centric approach. Our research programs already helped change practice for countless individuals word-wide. Join us!
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