Nature Reviews Gastroenterology & Hepatology
@NatRevGastroHep
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We publish #gastroenterology & #hepatology Reviews and opinion. #GastroEdPick selections by the Editors: Katrina, Jordan & Eleni | #MedTwitter | #ScienceTwitter
London, UK
Joined October 2011
Our FEBRUARY ISSUE is live! Year in Review 2024, cirrhosis & health disparities, immune checkpoint inhibitors & liver injury, gastrointestinal lymphatics, and much more! .
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The gut and the liver are characterized by mutual interactions between both organs, the #microbiome, diet and other environmental factors - the gut–liver axis. More in this REVIEW
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NEW! This REVIEW examines how the maternal gut #microbiome in pregnancy influences the developing immune system .
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New online! The gut–brain axis and pain signalling mechanisms in the gastrointestinal tract
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New content online: Cholangiocarcinoma 2020: the next horizon in mechanisms and management
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Seen at #UEGweek #UEGWeek2024 - Timon Adolph talking about the role of diet in the pathogenesis of GI disease, this figure on diet and gut inflammation, . read the Review here
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New content online: Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis
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New content online: Fermented foods and gastrointestinal health: underlying mechanisms
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From our current issue, this REVIEW describes the mechanisms of mucosal healing and how they might be altered in #IBD and discusses potential therapeutic approaches to promote mucosal healing and regeneration.
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New content online: Macrophages in intestinal homeostasis and inflammatory bowel disease
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New content online: Mechanisms of metastatic colorectal cancer
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New content online: The maternal gut microbiome in pregnancy: implications for the developing immune system
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New content online: The metabolic nature of inflammatory bowel diseases
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New content online: Ultra-processed foods and food additives in gut health and disease
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Seen at #UEGWeek #UEGWeek2024 this Figure on signalling pathways of JAK inhibitors for IBD. Read the Review here
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New content online: The role of goblet cells and mucus in intestinal homeostasis
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New content online: The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease
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It's #WorldMicrobiomeDay today and this year the theme is diversity. There is certainly a diverse #microbiota in our guts, which can be influenced by food. Read more in this REVIEW ->
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Dysregulated monocytes and #macrophages are a characteristic feature of intestinal #inflammation. Find out more in this REVIEW on the role of macrophages in intestinal homeostasis and #IBD
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New content online: The many means of conversation between the brain and the gut
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New online! Current and emerging strategies for the prevention of hepatocellular carcinoma
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REVIEW | Early detection of pancreatic cancer using DNA-based molecular approaches.
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REVIEW | #Metabolomics and lipidomics in #NAFLD: biomarkers and non-invasive diagnostic tests.
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New content online: Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?
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Fermented foods have gained popularity owing to their health-promoting potential - this REVIEW discusses the benefits of #fermentedfoods in gut health and disease, and how specific microbes, food components and bioactive compounds exert their effects.
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No.1 in our most impactful articles of 2024 (Altmetrics). This REVIEW on ultra-processed foods and food additives in gut health and disease by @ProfWhelan, @AaronBancil, James Lindsay & @BenoitChassaing. #sharedit link:
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Various goblet cells have differing roles in the adult small and large #intestine, find out more in this REVIEW
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New online! Dietary and metabolic effects on intestinal stem cells in health and disease
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New content online: A new era in obesity management
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New content online: Gut feelings: mechanosensing in the gastrointestinal tract
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REVIEW | Modern therapeutic approaches for the treatment of malignant liver tumours.
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NEW! REVIEW | #Metabolomics and lipidomics in #NAFLD: biomarkers and non-invasive diagnostic tests. #fattyliver
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Check out this #NatureResearch web collection on the #gut-#brain axis. Neuroimmune, #microbiota & more! #neurogastro
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New online! Delving the depths of ‘terra incognita’ in the human intestine — the small intestinal microbiota
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New content online: Gut microbiota in overweight and obesity: crosstalk with adipose tissue
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New content online: Neutrophils: from IBD to the gut microbiota
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This Review explores the role of diet, microbes & their metabolites in #coloncancer #CRC #WorldCancerDay
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No.9 in our most impactful articles of the year (Altmetrics). This Review by @KimMeerschaert & @IsaacMChiu on the gut-brain axis and pain signalling mechanisms in the gastrointestinal tract.
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New content online: Cell death in pancreatic cancer: from pathogenesis to therapy
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New content online: Pathophysiology of gastro-oesophageal reflux disease: implications for diagnosis and management
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NEW REVIEW! | The role of short-chain fatty acids in #microbiota–gut–brain communication.#gutbrainaxis #microbiome.
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NEW THIS WEEK! . REVIEW | Gut immune cell trafficking: inter-organ communication and immune-mediated #inflammation.
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No.7 in our top10 articles that grabbed your attention (according to Altmetrics) - this REVIEW on gut #microbiota metabolites as key actors in inflammatory bowel disease. #IBD
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New online! Metabolic health across the ages: how microbiota members support our well-being
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New content online: GLP1 agonists: current and future landscape of clinical trials for patients with metabolic dysfunction
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Best of 2021 - ALTMETRICS . no.5 is this REVIEW on Dietary carbohydrates and fats in nonalcoholic fatty liver disease.By Yki-Jarvinen, Luukkonen, Hodson & @TheMooreLab ..Read-only link #MAFLD #NAFLD #fattyliver
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New content online: Dietary management of adults with IBD — the emerging role of dietary therapy
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What is a #postbiotic? . NEW CONSENSUS STATEMENT from @ISAPPscience on the definition and scope of the term. #openaccess
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#MASLD (#NAFLD) & alcohol-related liver disease share pathophysiological features and are leading causes of chronic liver disease worldwide. Find out more about their intersection & management in this REVIEW.#WorldLiverDay
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REVIEW | Modern therapeutic approaches for the treatment of malignant liver tumours.
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NEW! #NewsandViews From #NAFLD to #MAFLD: when pathophysiology succeeds. Herbert Tilg & @MariaEffenberg1 discuss the proposed name change to MAFLD - metabolic associated fatty liver disease .
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NEW online! Nonalcoholic #fattyliver disease (#NAFLD) has become the most common form of chronic liver disease in children and adolescents. This REVIEW discusses the latest knowledge of epidemiology, pathogenesis & management. #obesity.
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📢Out now! This new Consensus Statement on Advancing the global public health agenda for #NAFLD .FREE Led by @JVLazarus & an international list of experts, the article aims to put NAFLD in the NCD spotlight @EASL_ilf. #fattyliver #MAFLD
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No.4 in our most impactful articles of 2024 (Altmetrics). This recent REVIEW on antibiotic-perturbed #microbiota and the role of #probiotics.
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New content online: Enteric neurons and gut homeostasis
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New online! A new treatment and updated clinical practice guidelines for MASLD
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No.2 in our most impactful articles of 2024 (Altmetrics). This REVIEW on the effects of dietary fibre on metabolic health and #obesity by Deehan, Mocanu & Madsen.
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#Inflammation and #fibrosis are closely linked in chronic liver diseases. This REVIEW discusses how immune cell recruitment and wound healing processes can lead to non-functional scar tissue, potentially causing organ failure.
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New content online: The promise of the gut microbiome as part of individualized treatment strategies
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Out for #DDW2024 @DanielDickstein & colleagues review pleasurable and problematic receptive anal intercourse in #gastrointestinal disease & cancer - the disease itself & its management can affect RAI and it’s important to counsel patients on sexual health.
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With rising #obesity rates, #NASH-related #hepatocellularcarcinoma (HCC) is becoming more prevalent. This REVIEW provides an in-depth look at the mechanisms driving NASH-HCC and discusses tailored therapeutic approaches. #MASH #livercancer
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REVIEW | The role of #diet in the aetiopathogenesis of inflammatory bowel disease.#IBD #CrohnsDisease #colitis.
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New content online: Effects of dietary fibre on metabolic health and obesity
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REVIEW | Utilizing the gut #microbiome in decompensated #cirrhosis and acute-on-chronic liver failure. This Figure summarises strategies to target the gut #microbiota in cirrhosis
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New content online: The intestine as an endocrine organ and the role of gut hormones in metabolic regulation
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It's that end of the year time when we count down some of our most impactful articles (in terms of Altmetrics score). No.10 This Perspective led by @Pdorrestein1 on the changing metabolic landscape of bile acids.
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NEW COMMENT arguing that now is the time tor re-examine the definition of #NAFLD - the vast majority of those with NAFLD do not develop clinically significant liver disease & the most frequent individual cause of death in those with NAFLD is #cardiovasculardisease
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NEW! REVIEW. #Microbiome risk profiles as biomarkers for inflammatory and #metabolic disorders.
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Our OCTOBER FOCUS ISSUE ON LIVER FIBROSIS is live! Liver inflammation and cellular stress in fibrosis, HSCs and liver cancer, antifibrotic therapeutic strategies, and much more! #livertwitter #livercancer
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Best of 2021 - CITATIONS . No.4 is this REVIEW on Advances in #immunotherapy for #hepatocellularcarcinoma .Read-only link #livercancer
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New content online: The role of oral bacteria in inflammatory bowel disease
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AUGUST ISSUE | REVIEW. Attaining mucosal healing without immunosuppression is an attractive option for the treatment of #IBD. This Review describes the mechanisms of mucosal healing and how they might be altered in IBD.
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New content online: Location is important: differentiation between ileal and colonic Crohn’s disease
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New content online: IgG4-related diseases of the digestive tract
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#Obesity, #diabetes & #NAFLD can coexist, find out more in this REVIEW on the complex links between NAFLD & type 2 diabetes mellitus. #worldobesityday
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New content online: Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms
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New Review online ICYMI | Here, the authors summarize therapies for the treatment of malignant #liver tumours, focusing on surgical & ablative approaches & how they align with therapies such as anticancer drugs or radiotherapy. Find it here: #LiverCancer
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New content online: Cellular and molecular basis of proximal small intestine disorders
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New content online: Viscera affectum anno: the gut beyond eating behaviours
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ILC3s orchestrate tissue physiology and immune tolerance in the gut. Check out this new REVIEW on group 3 innate lymphoid cells in intestinal health and disease.
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NEW! REVIEW on the role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology.
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New content online: A Roadmap for the Human Gut Cell Atlas
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New content online: Lifestyle interventions in nonalcoholic fatty liver disease
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GUT–BRAIN AXIS IN 2020 | Diego Bohorquez discusses #GutBrain biology in 2020 & how 3 remarkable studies have expanded our knowledge on how the #gut makes sense of its environment to guide brain functions & behaviors beyond food #YearInReview @gutbrains
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