Dan Clinton
@DanClintonRN
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Nurse, Tutor, Author. Believer in good definitions, the scientific method, & comparing benefits & harms in like terms. Seeking to prevent iatrogenic harm.
Bradford, MA
Joined March 2009
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Physicians are such nonscientists you can show them their own data shows noncorrelations between LDL-C and ASCVD, HIV and AIDS, amyloid and Alzheimer’s that falsify their hypothesis and they just don’t care.
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@adamcifu
“I’m only still here because I didn’t listen to knuckleheads like you,” as he lights a cigar
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@SouthlandPost
200,000K isn’t enough for her and only getting fired isn’t enough for those cops and the judge
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@AaronSiriSG
Most people in medicine have missed that all sorts of things with vaccines have essentially been grandfathered in and the kinds of studies that could prove causality with neurodevelopmental outcomes and are needed to prove safety have not been performed. The tail is too short.
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Here’s the scam: lump 5 endpoints together to make it so the drug only has to have the tiniest efficacy to achieve a statistically-significant endpoint. Then stop the study early before all the individual adverse effects and death achieve significance.
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This is how simpleminded many cardiologists are when it comes to ASCVD. And they’ll never give it up because it would require acknowledging being fundamentally wrong. They’ve directly killed patients to lower LDL-C. That creates a ton of cognitive inertia.
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@drlouisenewson
You’re a terrible scientist. Did you notice women being prescribed more antidepressants in literally every age bracket? And are you aware association is but the first of many criteria needed to establish causality?
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@marklewismd
I had to see infectious disease once and he said my case was interesting. That’s not what I wanted to hear. This was one of the few times I wanted to be described as “unremarkable.”
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Can almost all of humanity sign a letter complaining that you and other idiot virologists are endangering all of us with your lies and stupidity?
collaborative formal complaint of group of scientists continuously attacked by a Rutgers professor. Ok to disagree but this has been just crazy. I do hope
@RutgersU
takes a serious look at this. Universities should work with a code of conduct . .
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@Alicewants2know
@holmanm
Mind boggling isn’t it? Anyone who can’t see the danger even from the published results of FOURIER doesn’t really know what they’re talking about. The idea that many medical doctors fail to understand more death in every metric constitutes net harm is terrifying.
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Unless you’ve worked with medical doctors directly you can’t understand how far many of them will distort reality to avoid being wrong. The case can be open and shut, incontrovertible, and they find some way in their head to weasel out of responsibility.
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@drkeithsiau
What laxative do you prefer in the elderly? I like polyethylene glycol (MiraLAX).
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@WilliamAird4
My understanding is HCT is about 3x your Hgb but more susceptible to changes in fluid status and gives better data about the viscosity of the blood while Hgb provides better data about oxygen carrying capacity
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Nailed it. I have a lot of respect for
@R_H_Ebright
&
@Bryce_Nickels
for their fierce pushback on the demonstrably false and demonstrably ill-intended attempts very early to create the false belief SARS-COV-2 did not and could not have been a product of gain-of-function research
@R_H_Ebright
@quay_dr
Richard Ebright identifies the source of the intensity around the COVID origins debate as a culture in virology that resists considering the enormous unintended consequences of gain-of-function research and resists regulation.
@R_H_Ebright
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@DrPaulOffit
Dr. Offit, did you not spread misinformation about the COVID vaccine? Did you err in calling to mandate the vaccine? Are college mandates for boosters for young men dangerous?
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@JaymetheRN
Call me old fashioned, but I'd rather give analgesics that are shown to work for pain than an anticonvulsant that is also a little helpful for some nerve pain.
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@drkeithsiau
In the US we don’t routinely check NG tube placement with X-ray. Weird cultural difference.
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It seems like different nutrition camps like to argue over the finer points when all agree 1) cut way back on processed carbs 2) eat more real food
Don’t make it so hard.
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She’s right. Psychiatrists are as susceptible to blind spots in their thinking and biases that make them minimize harms as much as anyone else. I don’t think we should dismiss and discard people who are saying, “This hurt me.”
Labelling harmed patients as anti-psychiatry and saying they should be ignored just reminds of the stigmatising attitudes in the mental health system, labelling people as abnormal and often treating them very badly. Stigma pervades the whole system.
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@drkeithsiau
Revenge on the neighbor who reported me to my homeowner’s association for putting out my trash can the night before pickup instead of the morning of
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@MarionKoopmans
@RutgersU
Pointing out that GOF virologists were caught lying, your work is dangerous, & regulation is needed b/c you all are stupid and untrustworthy and may have caused a global pandemic then committed scientific fraud to cover it up isn’t harassment. It’s a well supported hypothesis
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@drtanmoy
They don’t deny statins are diabetogenic any more; they’re just in denial the diabetogenic effects may cause net harm over time . . . despite it being known for at least a decade A1C better predicts ASCVD than LDL-C
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@MaddieMierMD
When I was a very young nurse I documented that Starfire was an autistic patient’s favorite Teen Titan. I thought it could be a good conversation starter
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@PurelyPolitic
@OGdukeneurosurg
The pattern of the white matter in the cerebellum is called the arbor vitae because of its resemblance to a tree
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Dr. Prasad gets criticized a lot, even accused of spreading “misinformation.” But he’s often right. If you’re good at math and thinking you’ll hold minority views and recognize lots of iatrogenic harm in today’s world. That’ll make you controversial.
Sorry, no way.
There's no reliable evidence this vaccine lowers the risk of covid. FDA did not ask for any randomized studies.
There is no evidence that repeated boosters lower the risk of long COVID
No other nation recommends boosters for young healthy people who have had covid
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@KenDBerryMD
“People who think any scientific fact is indisputable don’t understand about scientific facts.” - Nobel Laureate Kary Mullis
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It’s definitely a great time to be an Alzheimer’s researcher. Yet, remarkably, almost unbelievably, some neurologists have managed to make having unstoppable progressive dementia that often leads to an indignant end and overall misery worse w/ murderous ineffective drugs
In
@DementiaNeuro
I argue that after lecanemab's full approval, now is a good time to be an AD researcher (we have impetus), & we should also use this impetus to promote the variety of therapeutic targets.
I cite
@VincentPlanche
@nvillain_alz
&
@cpiller
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Modern medicine does not understand what “safe and effective” means because of the captured, feckless FDA, corrupt medical journals (NEJM), and business oriented, pharmaceutically-sponsored professional societies (all of them).
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If you give someone a drug to prevent cardiovascular disease and the patients discordantly die more overall and of cardiovascular disease they can’t be claimed to have benefitted from it. These researchers killed people then tried to claim positive results
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@DrHermiz
She’s been spiraling for a while. The weight of trying to cover up complicity in acts that killed so many must be heavy.
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Heck, call it carbohydrate toxicity or just plain old hyperglycemia. Why even be that fancy? Just say your blood sugar is too high and that sugar comes from eating carbohydrates
Most doctors and dieticians tell their patients that T2D is chronic-progressive and requires tight medical control. They promote a lifestyle high in carbs and low in fat.
Just call it for what it is and treat the root cause. People are entitled to an informed choice and health.
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@TheBlondeRN
@DGlaucomflecken
Don’t use it. That’s an error. You can use eye drops in the ear but not the reverse. Call the doctor.
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@Jenniferhochsc2
You’re predictably terrible at apologizing. This non-apology has made you even less likable.
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@TraumaSoapBoxes
NCLEX is moving away from the nursing process, substituting “Analyze Data” for “Nursing Diagnoses.” Care plans + diagnoses are a good intellectual framework. But we also need to teach how to interpret and prioritize findings. NCLEX is trying to move in that direction
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@ProfTimNoakes
Newer drugs bempedoic acid (Nextelol) and evolocumab (Repatha) were granted accelerated approval because they lower LDL. Subsequent follow up studies vs placebo showed numerically higher CV and all-cause mortality in the treatment group after > 100 mil worth
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These guys generate good content
(I have no affiliation, just a genuine recommendation) for those with an interest in pharmacology. Rosuvastatin also has the longest half life and is preferred in clients with liver disease
#nclex
#statins
If you put strong passwords like this;
Make sure the spelling is correct 🥲
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@DrEenfeldt
@theproof
@YouTube
If you think nuts and olive oil are bad because they don’t offer a lot of satiety per calorie that just shows the problems with the metric satiety per calorie
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Of all the stupidity in healthcare, the inability of so many to recognize that Type 2 diabetes simply means an elevated blood sugar, and that blood sugar is modifiable through carbohydrate restriction, is up there.
A very much over-simplistic take. While these ideas may resonate with many in the low-carb community; it's misinformation & thus unhelpful for patients.
💬 Type II diabetics can do well on a high-carb plan (especially if they lose weight/fat).
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@R_H_Ebright
There is no reality in which funding gain-of-function or enhancement of pathogens of pandemic potential in a Chinese lab makes sense.
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Anyone who presents relative risk alone seeks to deceive. A real scientist would present the relative risk, absolute risk, and number needed to treat together because all 3 are needed to properly interpret the finding’s significance
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@DrAkhilRaghavan
Midazolam works the fastest IM, lorazepam works the fastest IV, and diazepam rectal gel gets absorbed the fastest rectally hence its use as a prefilled rectal syringe
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@KaraPepperMD
Because the risk to benefit ratio is favorable for a potentially life saving surgery and not for in vitro fertilization/egg retrieval
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Our government agencies & professional medical societies are functionally extensions of a profit-driven pharmaceutical industry that spends on advertising and can create a false reality by selectively highlighting data. That’s an unfortunate and uncomfortable truth, but the truth
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@theproof
Simon, I’m seriously not trying to troll you, but you’ve gone down a dry well with these guests. You can’t assume a benefit because something lowers lipids both because it’s a bad predictor and because it may exert other effects.
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@_eleanorina
@adamcifu
Hasn’t nutrition kind of come full circle? It used to be red meat would kill you and wheat germ was healthy. Now unprocessed meat is healthy and all these processed grains will kill you
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@PHCukorg
@MohammedAlo
I would've liked to have seen him speak and engage in a live back and forth. Put him on a stage and see if he understands the definition of Type II DM, ask why low-density lipoproteins are inherently atherogenic but intermediate aren't and why ASCVD "can't occur" w/ LDL < 30
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@quay_dr
There is no reality where it makes sense for the American taxpayer to pay to make dangerous viruses in China, and it’s a national security issue that those at the NIH who approved it are held responsible
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@SBakerMD
@LDLSkeptic
Did you see new paper showing no association between LDL-C and atherosclerotic heart disease from about 80 to 180 mg/dL? A stunning noncorrelation
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Gender equality has come to CV disease. Now an equal number of women and men were killed by bempedoic acid. Hurrah!
Special request from
@DrMarthaGulati
! Adding CLEAR outcomes to the “line of parity”in a shareable slide! First nonstatin outcome trial since to have 50% women. Lean in ♥️♥️♥️
@EsperionInc
@Drlipid
@CMichaelGibson
@ErinMichos
@DBelardoMD
@PeterAttiaMD
@Drroxmehran
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Do some cardiologists hate Nick and Dave because they make correct predictions and behave like scientists? They test hypotheses whereas preventative cardiologists prescribe children drugs that are overtly murderous to lower a surrogate marker
🚨
#OreoVsStatin
- PUBLISHED!🚨
@Oreo
cookies were 💥2X as potent💥 at lowering my LDL cholesterol (LDL-C) compared to high-intensity statin therapy!
What you NEED to know...
👉This was a metabolic demonstration, a 'do not do this at home' experiment
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It’s not self-evident to a disturbing number of physicians that a prescription drug need not be proven to murder to be unsafe. Drugs need to be shown not murderous to be thought safe.
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@GoodishIntent
Best way to tx an acid-base imbalance is to fix the underlying cause, but bicarbonate doesn’t seem unreasonable for a pH < 6.9, particularly if hyperkalemic
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@houmanhemmati
They seek to make themselves uncriticizable so their axioms can’t be challenged and falsified
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@nicknorwitz
Lipidologists will do anything to avoid realizing they’ve dedicated their lives and completed a fellowship in a flawed construct without realizing it
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@WashburneAlex
They called Montagnier a conspiracy theorist for noting that even though he was a Nobel Laureate for first isolating HIV
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@realDaveFeldman
@PeterAttiaMD
@foundmyfitness
You’re hitting on an important point, Dave. Cardiologists extrapolate data from FH pts to the general population, but that would be a mistake if FH causes dysfunctional LDL-C in addition to high LDL-C or it also causes other artherogenic effects that serve as a lurking variable
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“Medical science” is weird enough that a weak association, sometimes even a completely imagined tautological association, can be misconstrued as proof sufficient enough to establish a branch of medical science
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@MarionKoopmans
@RutgersU
Can almost all of humanity sign a letter complaining that you and other idiot virologists are endangering all of us with your lies and stupidity?
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Neurologists want to give a drug that seriously damages 1.2% of brains to slow decline an imperceptible 2.5%, cardiologists give drugs associated w/ more death vs placebo, and psychiatrists reference antidepressants working as well as placebo to justify their use. Idiocy abounds.
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@ProfTimNoakes
Medicine is so complicated physicians can’t fact check everything. And if you’re at the bottom of a hierarchy 300K in debt are you going to rock the boat? They’re incentivized not to have independent thoughts.
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@NicoGagelmann
Radiology report: mild intervertebral disc disease most prominent at C6 and C7
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A relative risk in isolation can deceive. It is the sum of a drug’s absolute beneficial effects + adverse effects that determine if a drug exerts net benefit. Harms and benefits must be compared in like terms. RRR, ARR, NNT, NNH all must be weighed to calculate risk:benefit ratio
Thank you to Dr. Nicholas Miceli, Ph.D., ., Assoc Professor, Epidemiol & Public Health, for his comment on our paper: Reporting results selectively (relative risk without absolute risk) borders on unethical practice.
@KenDBerryMD
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@carolynharris24
@drlouisenewson
What an absurd, absolutist take. HRT can cause endometrial cancer, breast cancer, and fatal blood clots. The unstudied doses being used may not be in women’s best interest - they may relieve sx and cause net harm. Her practices should be scrutinized
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@MaryanneDemasi
@JAMAInternalMed
Statins became blockbuster drugs b/c of selectively highlighted relative risk reductions. A 33% lower rate of MI sounds great, but if that’s going from 0.03% to 0.02% the drug’s adverse effects (diabetogenic effects, drug-induced liver injury, myalgia) may outweigh any benefits
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@DavidSteensma
@DrRyanPDaly
If you’re eminent in your field and a terrible parent are you a success?
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@VPrasadMDMPH
The late Nobel Laureate biochemist Kary Mullis who invited the polymerase chain reaction (PCR) talked about how science fell under the control of the NIH and “it’s not 10,000 people in their own labs coming to their own conclusions,” so the fact that they all agree is meaningless
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@realDaveFeldman
Amazing how everything but carbohydrates and inactivity seems to cause diabetes lately.
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@drkeithsiau
I know this one! Cullen’s and Grey Turner are testable on the
#nclex
. Alcohol is the
#1
cause of chronic pancreatitis and
#2
cause of acute pancreatitis behind only biliary colic
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@babbymd
I grew up in a wealthy suburb of Boston. Lots of elite physicians were terribly absent parents.
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@CaulfieldTim
Hasn’t the distrust been earned? You’re blaming people who were right for being right and acting victimized on behalf of “science” for being called out on being wrong.
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Here’s my 3 min of testimony in opposition of donanemab. I maintain a drug associated with a 65% increased rate of death that kills 1 in 285 and destroys > 1% of brains cannot be called “safe” in an objective reality.
@DanClintonRN
Great job, I ripped it for you and for everyone else to see the absurdity of this approval.
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@PhilippMarkolin
When are you going to let this go and get a real job? You’re wrong and the things you say are silly at best.
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@Bryce_Nickels
@R_H_Ebright
Remember in 2017 when
@R_H_Ebright
correctly predicted the danger of both BSL-4 labs in China and the gain-of-function research on coronaviruses they were performing?
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@schowardjd
@ChrisODwyer93
@NicoGagelmann
Depending how you look at it, you could say he’s fortunate to have a pulse, back pain, and memory loss
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@TuckerGoodrich
Lipidologists also used fancy math to conclude heart disease would not occur at an LDL < 30. Then when the crazy bastards finally got there w/ Evolocumab the treatment group died more in every metric
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@NutritionMadeS3
They spent 108 mil dollars on a drug that didn’t save one life and was associated w/ almost 2x as much hyperuricemia, 1.5x elevated liver enzymes, 1.3x “renal impairment, 1.5x gout, and 1.83x the amount of cholelithiasis.
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@DoctorBryantDO
@MohammedAlo
@TimNoonanMD
@TuckerGoodrich
@FrogHarmless
@ZahcM
@FatEmperor
@PeterAttiaMD
More death in Evolocumab vs placebo despite lowering LDL 60% (at a cost of 200 mil) and 6% of pts died within 8 years despite median LDLs of 29
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@Bryce_Nickels
Bryce, what you have to understand is the people who killed millions and lied to cover it up are the real victims in this thing
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@nicknorwitz
I remember reading this back in 2010. Linear increased risk of MI with A1C > 5.5%.
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@quay_dr
I was impressed by your testimony and I’m glad you got a forum to put forth your analysis.
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This does seem to me like a tacit admission antidepressants don't work any better than placebo in Alz pts, so it's being prescribed exclusively because placebos work, which I'd argue gets ethically murky giving a drug with known harms but no known benefit over the belief it works
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@DrMcFillin
One of the biggest lies I was taught in nursing school was that stimulants only help people with ADHD
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Our blood only has about a teaspoon of glucose in it at any time and our body can create glucose from protein when needed. There are about 16 teaspoons of sugar in a 20 oz soda. That much liquid fructose over and over can eventually damage the liver + lead to insulin resistance
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@anish_koka
@altcap
@theallinpod
Detecting “subclinical disease” can’t be assumed to lead to better outcomes.
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I’ve made my argument about as well as I can, reported my concerns directly to prescribers, and have now submitted them to
@US_FDA
Thank you to all of you who helped me crystallize my thoughts. I got this done and took my kids to the playground 3x today so a productive Saturday
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@VPrasadMDMPH
A lot of medical doctors are terrible at interpreting the results of studies and most don’t even read them. They rely on pharma-funded professional organizations to do that and give them a flow sheet to follow
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@Marion436842126
Someone who accepts money to promote a drug associated with both increased cardiovascular death and all-cause mortality is a murderer. There are a shocking number of cardiologists and lipidologists who belong in jail who are still allowed to see patients and publish.
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@virologyanon
I don’t object to viruses taking piano lessons. I object to making viruses more pathogenic and transmissible.
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@Dallas_Holladay
You’re totally right to call me out and I own it. Clearly, I’m flawed and did “go off the rails.” Doesn’t excuse it but my son is on day 4 of a hospitalization and I (mis)interpreted your post as misapportioning blame on the MA and had a hysterical response. I apologize
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“How’d that experiment go?”
“After $190,000,000 of a drug to lower cholesterol the patients died 4% more, 5% more of cardiovascular disease, & 10% more “other CV death.”
“What a failure.”
“No, statistics make it a success. You just don’t understand statistics.” - Cardiology
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