Joyce Meiring
@psychescope
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Postdoc in Akhmanova lab @UniUtrecht. Cytoskeleton, 3D migration & light switchable cell biology tools | she/her. Bluesky: https://t.co/d21CbbFg0s
Joined April 2019
Pleased to share that the optogenetic microtubule severing tool #Optokatanin✂️ is now out in @CurrentBiology !!! Movie shows opto-katanin being used to locally sever microtubules in two locations (marked by blue boxes) inside a neuron.
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Hi! I was wondering if anyone has successfully cultured happy HEK293T cells in defined serum alternatives? If so what did you use?
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RT @ThornSesholdLab: @ blue skies, there is a collection of 150 chemical biologist accounts to make it really easy…
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When the blue dot is shown, blue light pulses are being locally applied inside the yellow circle, which induces the recruitment of the microtubule severase katanin p60 to microtubules. Upon p60 recruitment microtubules are locally disassembled and the ER network simplifies.
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@JCellBiol @JagerLeanne @psirez @Bijvoet_Centre Congratulations all! Really happy to see this out! 😊
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RT @JCellBiol: .@JagerLeanne, @psirez et al. @Bijvoet_Centre show that compacted and expanded microtubule lattice spacings coexist within c…
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I'll be talking about manipulating the cytoskeleton with #photopharmaceuticals and #optogenetic tools at this Monash Advanced Microscopy webinar. Anyone can join (if you are awake at 3pm AEST)!
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RT @ThornSesholdLab: Caged Epothilones* now out in Angewandte: congrats Carina & all! Stabilises #microtubule #cyt…
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A very elegant study by some of my colleagues on decrypting lysosomal protein trafficking! They combine synchronised transport (using the RUSH system) with APEX proximity labelling to map out the lysosomal protein trafficking pathway in neurons. 👏🏼 #POTATOMap 🥔🗺️
It's out!😭🕺First preprint as a PhD at the Farias Lab @ginny_farias where we investigated biosynthetic lysosomal membrane protein trafficking, delivery and interactome with Protein Origin, Trafficking And Targeting to Organelle Mapping (POTATOMap)🥔
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@ZihniLab @CurrentBiology Thank you!! All the plasmids are on Addgene now, but let me know if you have any questions 😊
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RT @JeffreyHaren: Nice example of actin retrograde flow in a gigantic lamellipodium. #cytoskeleton, #actin, #microscopy, #cell-motility, #s…
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Harriet Saunders, Cyntha van de Berg, et al. show how ciliary tip proteins cooperate to make slow growing #microtubules in their new preprint! Together they form a structure that looks like a champagne cork in a #microtubule 😍
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@Dipti_Rai_ 's fantastic paper on controlled release of microtubules from γ-TuRC by CAMSAPs is out!
💫NEW: Rai et al. report that CAMSAPs can bind to minus ends of #microtubules attached to #γtubulin ring complex (γ-TuRC) and drive microtubule release. They show that CDK5RAP2, but not CLASP2, inhibits CAMSAP-mediated microtubule release from γ-TuRC.
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RT @JosiahPassmore: Happy to share our final GelMap publication in @naturemethods! With @DamstraHugo😃 https://t.co/…
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RT @JeffreyHaren: Optogenetic control of the actin cytoskeleton in a neuroblastoma cell. Light is on when the white dot is visible. #micros…
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@christlet @SamStehbens Actually the image shows a thermo Alexa fluor highly cross preadsorbed goat anti mouse secondary, we've been seeing a lot of variability in cross reactivity between antibody batches unfortunately. 😔
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