LifeArc
@lifearc1
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Medical research non-profit transforming promising life science ideas into medical breakthroughs that change patients’ lives.
Stevenage, London, Edinburgh
Joined February 2009
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We're launching 4 Translational Centres for Rare Diseases!
1️⃣ Centre for Rare Respiratory Diseases
2️⃣ LifeArc
@Kidney_Research
Centre for Rare Kidney Diseases
3️⃣ Centre for Rare Mitochondrial Diseases
4️⃣ Centre for Acceleration of Rare Disease Trials
@MDUK_News
@4Lilyfoundation
3
35
96
📢 Breaking news! £1m awarded for cutting-edge
#MND
therapies
LifeArc,
@mndassoc
and
@MNDoddie5
have teamed up to fund
@UCL
researchers to progress the development of two pioneering
#MotorNeuronDisease
cell and gene therapy treatments.
Read more➡️
2
24
64
We've received US$1.3bn for royalty interests from work on the
#cancerimmunotherapy
pembrolizumab. We'll use these funds to advance promising research into health interventions. Learn more:
#collaboration
#translationalresearch
#bench
-to-bedside
0
17
58
LifeArc is proud to announce its pledge to match the fantastic
#fundraising
efforts of
@Leedsrhinos
Director of Rugby,
#KevinSinfield
for
@mndassoc
, creating a £1m fund to stimulate
#research
into practical
#treatments
.
Learn more here➡️
2
17
46
📢£4.25m
#ResearchGrant
awarded to kick start collaborative efforts to end
#MND
. LifeArc, alongside charities, patients, researchers & government research orgs, will support
#medicalrearch
at 6 UK unis to discover MND treatments.
➡️
#MNDAwarenessDay
1
17
44
📢 Today we launch our new £100m programme to urgently develop new
#healthcare
solutions for the more than 300,000 people living with
#bronchiectasis
and
#cysticfibrosis
in the UK – and many more worldwide 🧵
1
20
43
Announcing three new Gene Therapy Innovation Hubs - recipients of £18m joint funding with
@The_MRC
&
@BBSRC
to advance new genetic treatments with potential to transform care for millions of patients including those with
#RareDisease
(1/5)
1
15
44
🎬Watch "Turning the Tide" a groundbreaking MND documentary by
@UCL
:
Their gene therapy offers a promising treatment for MND.
#TurningtheTide
#MND
1
17
43
That's a wrap on
#LATSS2024
! Seeing over 700 scientists, experts, policy makers and innovators together discussing translation and life sciences has been incredible.
Thanks to all who attended and we look forward to seeing you again next year.
1
5
42
We're delighted to announce the appointment of Dr
@SamBarrell1
CBE as our new Chief Executive Officer.
She’ll join LifeArc as CEO on 1 October 2024.
0
10
41
Congratulations to our Translational Challenge leader, Catherine Kettleborough, on being awarded the prestigious Honorary Fellowship by the
@BritPharmSoc
.
This achievement is a testament to Catherine's impactful contributions to life science.
2
5
38
We're proud to announce we are sponsoring five
#Research
Fellowships at the
@DaphneJacksonTr
, in honour of our dear friend, colleague and trustee, Aisling Burnand CBE, 1964-2022.
For details about the available
#Fellowship
& application process, visit:
0
13
38
We are so sad to hear Doddie Weir has died. It's been a huge privilege to work with
@MNDoddie5
over the past couple of years, co-funding vital research into
#motorneurondisease
. Together with the MND community we'll continue striving for a world free of
#MND
.
RIP Doddie.
We're deeply saddened to share the news that our founder Doddie Weir has died. Doddie was a force of nature, a great family man, tremendous rugby player & loved & respected by all who knew him. Our love & best wishes are with his family.
Full statement:
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882
12K
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“You have the power to change the lives of people who are suffering terribly. We are behind you.”
A powerful message at the
#MND
@mndassoc
@MNDoddie5
@The_MRC
@NIHRresearch
workshop accelerating translational MND research from
@AberdareNic
@onein300
@dsetters
@AmmarAlChalabi
1
13
33
We're building a validated and robust portfolio of potential MND treatment targets with
@KingsCollegeLon
through our new partnership -- the MND STaR programme.
Learn more:
3
14
33
Alongside great talks, we have a 'Translating Science Through Art' exhibition happening all day at
#LATSS2024
. Some of the UK's top artists and scientists joined forces to create pieces that highlight rare diseases and their impact.
3
5
33
It's been an inspiring start to
#LATSS2024
, with talks from Stéphane Maikovsky, Patrick Chinnery, Dame Kate Bingham and Clare Terlouw and Lord James O'Shaughnessy leading us in.
0
5
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📢
@UKDRI
and the
@mndresearch
, supported by LifeArc, are launching a multi-million-pound project to speed up urgently- needed treatments for Motor Neuron Disease (
#MND
).
#LifeScience
#United2EndMND
1
14
30
📢 £1.3m awarded by the joint LifeArc &
@GOSHCharity
Fund to support
#TranslationalResearch
.
Researchers
@UCLchildhealth
&
@GreatOrmondSt
receive 4 grants to tackle
#RareDisease
in children and advance tests, treatments & cures. 🔬
More➡️
#LifeScience
0
8
30
We’re proud to be part of the new
#MND
Collaborative Partnership.
The £4.25m
#ResearchFunding
will seek to discover MND treatments by coordinating
#MedicalResearch
, developing better tests, data collection, and a new study.
Learn more➡️
#MNDAwarenessDay
0
5
31
We're pleased to welcome Professor Roger Barker as our new chair of neurodegeneration.
🔗
With vast expertise in clinical neuroscience, he'll help to drive our mission to tackle neurodegenerative conditions.🧬
1
6
31
We have been nominated for 'Most Significant Contribution to the MediScience Sector' at the 2024 European MediScience Awards! 🎉
The nomination is a fantastic testament to the brilliant work being done by our team.
0
3
30
We are so sad to hear of the passing of Rob Burrow CBE, a huge ambassador for people living with Motor Neuron Disease (MND).
We wish to thank Rob and his family for their dedication to raising awareness and funds for research in new treatments for MND. He was a true inspiration.
0
2
27
Our annual reception is an opportunity to thank everyone who worked with us to accelerate science for patients during the year, to reconnect with friends and forge new friendships.
Thank you to everyone who joined us this evening.
#lifearc2030
0
5
28
LifeArc and
@mndresearch
are pleased to announce that they are awarding
@sheffielduni
over half a million £
#funding
, to test pioneering
#genetherapy
#research
to treat
#motorneuronedisease
(
#MND
) and
#frontotemporaldementia
(
#FTD
) ➡️
@CGTCatapult
1
12
27
Yesterday, we hosted a workshop with
@asthmalunguk
about transforming diagnostic issues facing people with chronic lung conditions. See the artistic minutes below 🎨
Today we're at
#BTSWinter2023
(
@BTSrespiratory
) to continue talking about what more can be done.
3
15
27
“The future is bright and many people are working together to create new treatments for patients.”
Inspiring words from Tom Gillingwater during our
#alsmndsymp
panel discussion!
Find out about our work in
#MND
👇
#LifeArc2030
1
6
25
Today we are proud to launch our new
#LifeArc2030
#strategy
which outlines our commitment to spend up to £1.3 billion by 2030 to deliver new diagnostics, drugs, devices & digital solutions to transform the way diseases are prevented, identified & treated➡️
0
12
27
📢 Introducing the LifeArc Gene Therapy Innovation Fund!
Today we're launching a new £5m annual fund that will provide grants to academic researchers working on innovative
#GeneTherapy
technologies.
🧵 (1/3)
2
14
25
International £5m Funding Call now open: Preclinical discovery and development of repurpose drug candidate for Motor Neuron Disease (MND).🔬
🔗
Learn more at our pre-funding call workshop in early Feb 2024 - register here:
0
15
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As part of our
#MND
Translational Challenge, we’re excited to announce an innovative
#Partnership
with
@precisionlifeAI
, to accelerate the discovery and development of targeted
#Treatments
for people living with the condition🤝
Read the announcement ➡️
0
12
24
COVID-19 represents a global emergency. We are looking to fund
#research
which aims to repurpose already available, or in late stage of development,
#therapeutics
which have a clear path to patient within the timeframe of this pandemic. Find out more:
0
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We're looking forward to welcoming our partners this evening to
#celebrate
the launch of our
#RareDisease
Translational Challenge.🔬
To learn more about our
#RareDisease
Translational Challenge visit👉
1
6
24
We have issued a £10m funding call for the development of
#COVID
-19
#therapeutics
. Find out how to apply here:
0
12
20
A great way to round off the day at
#LATSS2024
– listening to
@ProfRWinston
and Lord David Willetts talk about turbocharging translational science in UK.
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1
24
We’ve joined up with
@TheCrick
to launch the LifeArc-Crick Translation Fund, making £5m available for Crick scientists to progress promising innovation to attract larger scale investment and development:
0
5
22
Today is
#WorldBronchiectasisDay
.
We are working with
@aluk_research
to raise awareness about bronchiectasis, why it needs attention and the research opportunities available. 🫁
Find out more:
0
12
24
Today is
#DravetSyndrome
Awareness day. We applaud Dr Rajvinder Karda at the
@ucl
in her work to
#research
pre-clinical gene therapy & editing treatments that LifeArc jointly fund with
@DravetUK
,
@GOSHCharity
and Sparks Charity. We wish the project every success!
#FightDravet
0
6
23
8 new fellows have been funded through our partnership with
@CrickAfricaNet
!
Alongside funding, we'll be on hand to offer expert training in translational science, and hands-on lab experience in Edinburgh and Stevenage.
Read more:
0
7
23
Thanks again to
@MNDoddie5
for the financial boost to help fund more research into treatments for MND
0
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A new study, part-funded by our MND Translational Challenge and partners
@mndassoc
, has shown how a combination of grafted replacement motor neurons and optical nerve stimulation can improve muscle function.
➡️
#MNDAdvocacy
#ALS
0
5
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Thanks for mentioning us
@AberdareNic
! It's great to be working with you on this exciting partnership to find treatments for
#MND
🙏🔑🔬
@MNDAssoc
@MNDScotland
@MNDoddie5
@The_MRC
@NIHRresearch
@KingsCollegeLon
@SheffieldUni
@LivUni
@ucl
@UniofOxford
@EdinburghUni
2
4
22
We are providing £5m to support the work of
@GenomiccStudy
@GenomicsEngland
to investigate why some people are affected more severely by
#COVID19
, plus increase our understanding about the disease. Part of our wider £27m fund for solutions to
#C19
. More:
0
8
22
New immunotherapy drug targets for cancer will be progressed through a multimillion-pound drug discovery alliance between
@CR_UK
, LifeArc and OnoPharma Ltd. Read more here
#drugdiscovery
#immunotherapy
#precisiononcology
0
11
22
As part of
#GlobalMNDAwarenessDay
, we’re eager to share how we’re accelerating scientific innovation and treatments for people living with
#MotorNeuroneDisease
.
Find out what we're doing to improve the lives of people living with
#MND
:
#United2EndMND
0
18
22
👏👏👏Huge congratulations to
@KevinSinfield
on completing his epic 101 mile challenge to raise funds and awareness for
#MND
. It's one of the conditions we're proud to be tackling with our partners
@mndassoc
,
@MNDoddie5
,
@The_MRC
, &
@NIHRresearch
.
#TheExtraMile
Finish line moment 🏁
Kevin Sinfield completes 101 miles in 24 hours in honour of
@Rob7Burrow
and families across the country affected by motor neurone disease.
Thank you to
@SallyNugent
and the
@BBCBreakfast
team for raising awareness 🧡
#TheExtraMile
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3
21
Delighted at today’s news!
@GOVUK
will commit £50 million towards
#MND
research thanks to the
#United2EndMND
campaign
@sajidjavid
Great job
@mndassoc
@MNDoddie5
@MNDScotland
@AmmarAlChalabi
@Rob7Burrow
@DoddieWeir5
!
Looking forward to working with you!
1
2
21
🥁We are launching a new service, Advise & Connect, to help projects focused on
#COVID19
or future viral outbreaks get access to our advice, network and potentially an award of up to £20,000.
#innovation
#AdviseAndConnect
Find out more and apply ➡️
0
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Thank you to
@AMRC
and the
#APPGonMedicalResearch
for a great event at
@UKHouseofLords
. LifeArc’s
@MelanieGLee
and
@CatrionaCrombie
joined esteemed peers to recognise the vital role of scientific collaboration and innovation in tackling
#Covid19
.
#research
#CovidResearchResponse
0
1
20
There's been a great buzz at our
#LifeArc2030
reception this evening and we are grateful to Professor Sir John Bell
@OxfordMedSci
for setting the scene for our new strategy - read more about it here:
0
2
21
A moving message from
@leedsrhinos
Director of Rugby,
#KevinSinfield
, to LifeArc.
"MND is not incurable, it has just been underfunded" - LifeArc working alongside the
@mndassoc
aim to change this.
#Research
#DrivingMNDResearch
0
8
20
We're investing £10 million into
@ukfuturehealth
, Britain's largest health research programme.
OFH will provide valuable clinical and genetic data that we can utilise to support research projects across our Translational Challenges.
🔗 Read more:
1
5
20
🫁New technology
LifeArc is partnering with
@NIHRresearch
and researchers at
@RoyalPapworth
to investigate if machine learning can detect dangerous lung infections in people with
#Bronchiectasis
and
#CysticFibrosis
days before symptoms appear.
➡️
2
10
20
Last month we announced a new
#partnership
with the
@cftrust
to co-fund a £15m
#research
programme to advance
#CysticFibrosis
treatments 🫁
We look forward to making new discoveries, forging unified networks and training the next generation of
#scientists
➡️
0
5
15
Happy
#InternationalWomensDay
! Some of the remarkable women at LifeArc have shared valuable career tips➡️
Today and everyday, it's critical to
#investinwomen
and inspire future generations to build careers in life science.
#IWD24
0
5
18
UK Government announces outline plans for £50 million
#MotorNeuronDisease
research funding🤝
We cautiously welcome the news & are delighted the MND Partnership has received an additional £2m to
#Research
the causes of MND & search for new treatments💊
➡️
0
5
18
We teamed up with
@MDUK_News
to create a £1M fund to accelerate new, effective
#treatments
for people living with congenital muscular dystrophies disease.
Register for the webinar to find out more➡️
#ResearchProject
#MuscularDystrophy
0
4
19
“This is fantastic news... We know that life science can be life-changing, but it stands the best chance if researchers in the UK are able to work closely with the world’s top talent, wherever they are.” - Melanie Lee, CEO
Read our full response here 👉
UK to rejoin EU's £85bn Horizon science research programme after being frozen out over a post-Brexit row
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3
19
Thank you Dame
@Katebingham2
, managing partner at SV Health Investors, for the uplifting keynote speech this evening.
It was inspiring to hear what made the
#Vaccine
Taskforce - “the ultimate translation achievement” - work & your vision of what is possible in the future.
0
5
19
We're still buzzing from
#LATSS2024
. It was incredible to see so many people come together and we're blown away by all the positive feedback!
Recordings of the sessions are coming soon on YouTube...
See you again next year!
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1
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📣 We're at
#ENCALS2023
in Barcelona this week 🐝
Paul Wright & our MND
#TranslationalChallenge
team are there with the int 🇺🇳community of researchers, industry reps, and charities - all dedicated to finding a cure for
#MND
.
More about us:
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1
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Great to have been at
#UKCFC
today to learn about the latest research from
@cftrust
and the
#TeamCF
community! 🙏👏
#cf
#cysticfibrosis
#alifeunlimited
0
3
18
The first projects to be funded through our £30 million strategic partnership with
@UKDRI
have been announced today!
Read about them and the initiative here:
0
8
19
RQ Biotechnology, a company we co-founded, has today signed an agreement granting
@AstraZeneca
an exclusive worldwide licence to develop, manufacture and commercialise RQ Bio’s early-stage antibodies against SARS-CoV-2.
@UniofOxford
@GeorgeFreemanMP
0
5
19
Today we celebrate International Day of Women and Girls in Science! 👩🔬
We're always looking for incredible women to join us. If you'd like to contribute your skills to meaningful projects that impact lives, check out our current roles:
#WomenInScience
0
4
18
Expressions of interest for our £5m drug repurposing call for motor neuron disease open in February. Before that, join our webinar to answer your questions and dive into the details about the funding call -
🕒 5 February, 3 to 4:30pm
📍 Online (Zoom)
1
13
17
Imagine a reality where every breath is a struggle. Every 5 minutes, someone will die due to a lung condition.
Read our report with
@aluk_research
to learn how we are transforming respiratory diagnostics:
0
6
17
A new report details how £1.1 billion was invested by the Government and charities in rare diseases.➡️
We’re proud to play a part in funding rare disease research, ultimately helping bring benefits to patients.
@NIHRresearch
@The_MRC
1
6
18
Following our £10m COVID-19 funding call in March, we announced that fifteen clinical trials into potential
#therapeutics
for
#COVID
ー19 are set to start, read more here:
2
12
17
Great to celebrate all the remarkable
#WomenInSTEM
here at LifeArc, watch Zhi Yao, our senior scientist in target validation group giving some advice to girls in school who are interested in Science here:
#February11
#WomenInScience
#WomenInSTEM
0
1
16
LifeArc and the
@The_MRC
create £16m fund to establish Gene Therapy Innovation Hubs. These hubs aim to accelerate potentially curative
#genetherapy
treatments towards patients. Read more here
0
17
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Did you know our
#PhilanthropicFund
has helped to accelerate
#GeneTherapy
research? 🔬
We partnered with
@ucl
's
@Dr_RKarda
to carry out research aimed at improving the lives of patients with
#DravetSyndrome
Learn more here ➡️
0
4
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LifeArc will sponsor two new postdoctoral fellowships at
@ClevelandClinic
, led by
@SStaufferPhD
and Andy Merritt. Fellows will conduct early-stage research that has high potential to benefit patients. More 👇
1
6
17
We've partnered with
@ReActAfrica_RAN
to launch a $1.5m initiative to combat antimicrobial resistance (AMR) in Zambia and Kenya.
We aim to deliver knowledge and digital tools to improve patient care and make long-term policy and practice improvements:
0
7
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Thanks to
@MNDoddie5
for joining the fund established by LifeArc and
@mndassoc
.
The additional money means we can jointly support more promising research projects aimed at realising effective
#MND
#treatments
.
➡️
0
9
17
We are looking forward to attending the 3rd European
#Bronchiectasis
Workshop in Milan this week to learn about the latest advances in
#Research
🫁
Find out about our
#LifeArc2030
Chronic Respiratory Initiative➡️
#EBROW2023
0
6
17
Last night we hosted the official launch of our
#RareDiseaseTranslational
Challenge.
We'd like to say a huge thank you to those who attended the reception and thank our speakers for delivering inspiring talks throughout the evening.
#RDTC
#LifeArc2030
1
6
17
Dr Ian Campbell is joining LifeArc as Chief Business Officer. Ian brings a wealth of experience in the
#lifescience
industry and will be responsible for LifeArc’s business development and partnerships. Read more here:
#translationalscience
1
5
17
“For anyone with MND, no matter how soon we are diagnosed, there are no treatments for us.”
A moving interview with
@AberdareNic
on
#BBCBreakfast
on why research into motor neurone disease is so urgent.
#ALS
#MND
#United2EndMND
@profcjmcdermott
@mndassoc
@MNDoddie5
@MNDScotland
“Please rethink the way you are approaching this and just let these scientists do their work.”
Nicola Waters, who is living with Motor Neurone Disease, urges the government to free up the £50 million funding that was announced last year ⤵️
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Today we celebrate
@WomensScienceDay
at LifeArc where 50% of our employees are women. We asked some of our scientists about their career paths and advice they would give to inspire the next generation of girls. Read more here:
#February11
#WomenInScience
0
3
14
We’ve signed a new agreement with
@Biocartis_
which will enable us to explore the development of highly innovative assays and ultimately develop new tests that benefit patients. Read more here:
#Idylla
™
#MolecularDiagnostics
1
6
16
Thank you to
@Rob7Burrow
, Rob's family and the BBC for making this moving documentary about life with
#MND
.
At LifeArc we continue to work with our partners to make a difference for people affected by
#MotorNeuronDisease
.
@mndassoc
@MNDScotland
@MNDoddie5
@The_MRC
@NIHRresearch
Thank you for watching ‘Rob Burrow: Living with MND’
The search continues for a cure.
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16
Congratulations to these three recipients of a major investment in cutting-edge gene therapy in the UK. We wish you every success in accelerating academic research programmes down the path to patient benefit.
#RareDisease
#GeneTherapy
0
2
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Today marks the International Day of Women and Girls in Science, we asked some of our fantastic female scientists what advice they would give to girls in school now, watch what Afrah Sattikar had to say here:
#February11
#WomenInScience
#WomenInSTEM
1
7
16
Congrats to Prof
@janedaviescf
on being awarded an OBE 🎉
This honour is a testament to her dedicated service to people with cystic fibrosis, and we're proud to have her on the scientific advisory board for our Chronic Respiratory Infection Translational Challenge.
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Today is International Women’s Day! ♀️
To mark this day, we’re championing the campaign’s official theme and challenging our colleagues to
#BreakTheBias
and strike their best pose. 🙅♀️
#IWD2022
#InternationalWomensDay
#IWD
@womensday
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It's
#WearYellowDay
💛
As part of
#CFWeek
, this annual
#Fundraiser
held by the
@cftrust
enables you to be a part of life changing
#medicine
, funding
#research
& support for people living with
#CF
.
Find out more 👉.
0
4
16
For more details, you can read the full press release here:
0
6
16
Check out BBC Look North's interview with Dr Catriona Crombie, Head of LifeArc's Rare Disease Translational Challenge – talking about the clinical trial we funded to treat neuroferritinopathy, an ultra-rare, incurable brain disease.
🎥
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