Jon Chee
@jonchee_excedr
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CEO & Co-founder at @ExcedrInc 🔬 | Host at The Biotech Startups Podcast 🧬
San Francisco, CA
Joined February 2024
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I LOVE what’s happening with the interfacing of Academia and Industry.
I’ve spoken about this before, but when I was in academia, it was a completely different time.
There was no collaboration or crossover between them… There was no on-campus startup community.
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“One of the toughest things in life is to learn who to listen to, and at what point.”
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The best time to plant a tree was like ten years ago. The second best time is now.
The same goes for your content.
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“I didn't feel the need of spinning out companies. It wasn't the primary aim, quite frankly. It was a result of nobody seeing what this technology could do.”
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“Know your personnel” ← My high school lacrosse coach used to say that all the time, and I’ve never forgotten it.
The point was to set the people around you up for success.
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“The only way to have patient impact at scale is to unlock value for investors so that we can get the capital to repeatedly have patient impact.”
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The 4th and final part of my conversation with
@bitbio
CEO,
@MarkKotter
is now live on The Biotech Startups Podcast, and it’s a whirlwind of serendipity and strategy through the founding journey of .
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It’s a transition every founder and executive goes through… The skill sets you need as an individual contributor are very different from the ones you need as a manger and a leader.
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No government, or state, local or federal, likes to see brain drain.
Over the last 10+ years, that’s what has been happening in some of these areas that have a great university system… But the startup and entrepreneurial culture is not there.
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Would-be and first-time scientific founders, this one is for you.
In Part 2 of my The Biotech Startups Podcast conversation with Quin Wills, CSO and Co-founder of
@OchreBio
, we’re taking a deep dive into the many tough lessons you learn as a first-time founder.
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@UWCoMotion
I’m overwhelmed with excitement for how cool the life sciences environment is for the founders of today and tomorrow.
Can’t wait to see what the next 10 years hold….
#lifesciences
#biotechnology
#academia
#founders
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One of my favorite parts in my conversation with
@bitbio
CEO,
@MarkKotter
, is how we keep coming back to First Principles, and this idea of letting things be simple.
From finding a high-level sense of purpose at a time when he felt quite lost…
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"I started realizing that you get amazing skills, critical thinking, creativity, and founders of knowledge in academia. But if you want to make a real impact on the world, there is a lot you can do outside academia.
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Treat people how you want to be treated. That includes your vendors.
You can’t just squeeze them.
That’s a zero-sum game that’s eventually going to come back to bite you.
Aim for win-win instead.
It has longevity built right into it.
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I have a 100-year vision for
@ExcedrInc
.
So when I’m talking about things like “throwing best-in-class in-person events” or “Excedr Press” – I don’t really care what the timeline is for those things.
There’s no rush.
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"Don't forget to take time off to pursue something that's experiential for you, whatever that is. Don't shortchange yourself on that."
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In my ideal world, you can start a biotech startup anywhere you want.
The opportunity is more equally distributed, and the specific geography is greatly de-emphasized.
Maybe that's just the punk rock in me.
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Speaking of “pinch me” moments… Sharing the same stage as Professor David Baker and Jenny Cronin (
@croninja1
) at
@UWCoMotion
the other week?!
What even is my life?? 🤯
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The 3rd and final part of my conversation with
@Sherlock_Bio
President, CEO and Director, Bryan Dechairo is now live on The Biotech Startups Podcast, and it’s an incredible look at what it takes to bring consumer health products to market.
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Hearing what Vizgen President and CEO, Terry Lo, and his team are building – it’s super cool. And so is the journey to getting there.
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If there’s one theme to the 3rd part of my conversation with Martin Brenner, CEO & Chief Scientific Officer of
@iBIO_Official
, it’s that change is constant, flexibility is critical, and there is no replacement for a strong network – especially when you’re charting new territory.
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“If people don't want to work with you, it's because the vision is not big enough.”
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@ExcedrInc
And while I can’t personally do it all…
I can certainly look for ways to double down on the places Excedr (and our network) CAN add value.
Let’s get it!
#biotechnology
#lifesciences
#startups
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I have no real concept of what’s “normal” or not within an organization.
I only worked at a handful of jobs outside of Excedr, so I just don’t have a good control group for what that looks like.
And I think that naivete has helped me more than hurt me over the years.
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If you’re a seed-stage company, your next funding round is far from guaranteed.
Same for series A to B, B to C, etc…
It only gets harder.
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Part 2 of my conversation with Grant Aarons, Co-Founder and CEO of
@FabricNano
, is now live, and it is a master class in value creation and practical economics for founders… In my book, it’s an absolute must-listen.
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This is a theme that keeps coming up over and over again with guests on The Biotech Startups Podcast, so I’m not the only one who sees it.
Hard things are worth doing.
And the market is starting to agree.
#biotechnology
#lifesciences
#startups
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@ExcedrInc
I’m just too excited about it to keep it to myself.
I know I must sound like a broken record saying it, but I want today's and tomorrow’s biotech founders to have ALL the resources we didn’t have back in the day.
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“You know, we're keeping livers alive on machines these days. Do you want to sequence a few?”
Anyone who follows me knows how much I love a good serendipity story.
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Human ingenuity should be the only limiting factor to someone’s research.
That was really the founding thesis of Excedr 12+ years ago, and it’s still the core belief we operate under today.
But the cost of equipment is far from the only barrier.
Geography is still a big one.
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The first part of my conversation with President and CEO of
@Vizgen_Inc
, Terry Lo, is now live and I can’t wait for you to listen in.
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It’s a long game, but the payoff when it works can be huge, because by the time you have success, you’ve also dug such a big moat around yourself, that it’s incredibly defensible.
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In the first part of my conversation with
@insidepharma
, CEO of
@CybinInc
, on The Biotech Startups Podcast, we delve into the art of authentic connection in sales and leadership.
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@OchreBio
This episode is also a really interesting look at the early days of bioinformatics… so pop in your ear buds and queue it up, because we cover a lot of ground in these 25 min!
Apple Podcasts & Spotify links in the comments below! 👇🏽
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So what if the incumbents in your industry HAVE a strong point of view? And share it often and authentically?
While I’ve yet to see that from any of the really big players in a given space…
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But whenever I’m participating with Nucleate, or most recently, at
@UWCoMotion
and seeing a legendary professor and rockstar investor co-hosting an event…
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"We opened the lab in New York City. And very quickly we signed the first project with the pharma company and then the second one. But I think that the idea was to do what's right, even if you don't know how to do it."
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But I love seeing these up-and-coming hubs turning their attention to the sciences and looking for ways to broaden their support for those talent pools as well.
Let’s get it!
#lifesciences
#biotechnology
#startups
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@ExcedrInc
Whether it be a sales call, whether it be how we communicate on the Internet, whether I take a random Zoom with a grad student trying to figure out their next step…
It's all because of this alignment and vision.
So – whether you have a 100, 20, or 10-year vision…
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You know what gives me night terrors?
Thinking about the fact that the larger you get, the harder it gets to be nimble, flexible, and keep a balanced eye on both the macro AND the micro.
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@ExcedrInc
My vision for this is that it’s another free resource we’re creating… But that every publication is a deeper dive than we’ve ever been able to take before.
Once again – this is something that’s very much in the nascent planning stages…
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@ExcedrInc
I just want people to know that you can build a business in an infinite amount of ways.
It just has to, stylistically, be a fit with you.
#lifesciences
#biotechnology
#startups
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You're not going to get a biochemistry degree and wet lab experience on the Internet.
You have to do that yourself, in school.
That’s an important “moat” and competitive advantage that life sciences companies have.
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Sometimes, you have to look for the path of MOST resistance.
Everyone wants to have a capital-light, low-resistance business…
But SpaceX figured out how to make a reusable rocket, and that didn’t come cheap or easy.
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That’s always been one of our strengths at
@ExcedrInc
.
If you go to our website, you’ll see TONS of blogs and written resources, including the business side of running a biotech startup.
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@OchreBio
– Dealing with rejection, making mistakes, and being ok with the things that are a work in progress (we all have them)
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Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
Apple Podcasts:
Spotify:
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“Opportunity in life is like trying to grab the hair of a bald man with a beard once he's walked past.”
That’s one of my favorite quotes from Part 1 of my conversation with Ochre Bio CSO and Co-founder, Quin Wills on The Biotech Startups Podcast.
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"I think today, AI, artificial intelligence, is a term that is being thrown everywhere. And as a mathematician, I'm very worried about the... The hype that is creating. Like, yes, there is AI everywhere, but is there really AI out there?"
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“What is an engineering way to de-risk the possibility of reaching that type of prototype in the shortest amount of time possible?”
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And I hope I can persuade other life sciences founders to look at it that way too.
Your story matters now more than ever.
It’s time to start sharing it.
#lifesciences
#biotechnology
#marketing
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@NoamSolomon1
@Immunaitech
It's fascinating to hear how Noam's academic background prepared him for the entrepreneurial world and the impact he's making now.
Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
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Can I tell you how excited I am to have a fellow Berkely alum, Bryan Dechairo, President, CEO and Director of
@Sherlock_Bio
on the podcast?
We’re digging into the early days that set the foundation for Sherlock, including:
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For Excedr, the idea of extending your cash runway has always been our primary value proposition.
We’ve done well over the years, because no matter what the market mandates (e.g. growth at all costs or w/e it may be), it’s a concept that always fits.
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@vizgen_inc
In this episode, Terry fills in a ton of those gaps, and sort of shares the map for others to follow.
Apple Podcasts & Spotify links in the comments below! 👇🏽
Apple Podcasts:
Spotify:
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"I learned my first principles of leadership and management at home."
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👆It might be tempting to put any of those things into a spreadsheet and treat them all like “apples”...
But when there are actually apples, kiwis, plums, and cantaloupes in every category, that would be a really bad way to make a pie.
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So I think it’s time to stop looking at this kind of marketing as a cost center, or another chore you HAVE to do…
I look at it as an investment opportunity that will continue building our brand and creating persistent, differential returns for our business.
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@Sherlock_Bio
Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
Apple Podcasts:
Spotify:
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"The best innovation and problem solving comes with diverse teams. Diverse teams in terms of not only training and their expertise, but also diversity of thought and how they grew up."
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@ExcedrInc
In the next couple of years, I’d like to see us expanding on that, tapping our expert network, and launching Excedr Press to cover deep dives on company-building content, as well as the latest and greatest in cutting-edge scientific research.
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“The minute you need to go out and raise more money, you need to really seriously think about what is the team that's going to be around to take that money and turn it into real value.”
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Obviously, the podcast unlocks some of them in the conversations we document there.
But again, there’s only so deep you can go on any one topic in that format.
With the written word, however…
The possibilities are endless for deep dives.
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@vkhosla
@OchreBio
@ycombinator
Quin sends a huge round of thanks to his life partner for having the patience of a saint on this crazy journey; Professor Chris Holmes, his PhD and Post Doctoral Advisor at The University of Oxford; and everyone else who’s been patient with him along the way.
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@croninja1
@UWCoMotion
Luckily, I think that has to do more with my own level of excitement and passion for what people like Jenny and Professor Baker are doing, and far less to do with who I am (or am not) in relation to them.
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The second part of my conversation with
@Vizgen_Inc
President and CEO, Terry Lo, is now live on The Biotech Startups Podcast, and it’s packed full of gems for charting a career on the business side of the life sciences:
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Both my co-founder Jeff and I were very involved with student organizations when we were at Berkeley.
Jeff ran and helped build up the Berkeley Investment Group for close to 4 years.
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Pinch me. The community that’s forming around The Biotech Startups Podcast blows my mind.
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"My dream is that all the money that we raised, all the years of building this machine, will be translated to help people like my co-founder, Louis' late grandfather, and my wife's aunt that died a few years ago from breast cancer."
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The voice of experience helps you avoid making the same (or related) mistakes twice, but it can also start you down a slippery slope of putting the blinders on and thinking you have all the answers already.
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@Sherlock_Bio
– Structuring teams for creative problem solving and maximum impact
– And the musical-chairs reality behind getting people in the “right seat on the bus” as they continue to grow and evolve
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@croninja1
@UWCoMotion
Needless to say, this was a really cool milestone on my own founder’s journey.
Huge thanks to CoMotion for inviting us to be a part of it!
#biotechfounder
#biotech
#lifesciences
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Now, some of those same geographies are starting to focus more attention on life sciences startups as well.
It’s a different beast – a lot more resource-intensive both in terms of startup capital and specialized real estate needs (lab space).
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– Advice for younger professionals on embracing failure, taking risks, and not being too hard on themselves
It's an episode packed with wisdom gained from a lifetime of experiences in innovation and leadership.
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@fabricnano
@gaarons
Domenico Giannone, Lucrezia Reichlin from the London Business School, and everyone else who has provided guidance, a sounding board, and made it safe to pursue this massive mission.
Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
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What’s an under-recognized biotech hub you’d like to see get more support?
#biotechnology
#lifesciences
#founders
#startups
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@OchreBio
– Why the human element is 90% of running a company (even though the science is ALSO super important)
– The pain of finding out product-market fit isn’t guaranteed in the sciences after all
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@OchreBio
And while there’s no replacement for first-hand experience in so many of these cases…. Knowing where to be paying particular attention for those experiences is a big chunk of the lesson.
I so deeply resonate with so many of the lessons and experiences we discussed here…
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"My wife had to give up her job. And, you know, it was a big move. My daughter was seven years old. My son was five years old. My daughter drew a picture of me dragging them to a foreign land that had a precipice. A mountain and a precipice.
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@fabricnano
@gaarons
– Preparing for first launches, being ok with the possibility of failure, and keeping your eye on the prize
– Cultivating curiosity, getting comfortable with sales, and navigating the business side of science
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Something to consider.
There’s a lot of ways to get the job done, but it starts with getting the right people on board (regardless of their on-paper credentials).
Hire for Attitude, and Train for Aptitude.
#biotechnology
#startups
#lifesciences
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"The problem is not the money, which is a scary thing because what that means is the problem is the people, the problem is you, the problem is you have to go fix it yourself."
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"I didn't get good at the selling part until I let all of that mechanistic stuff go and learned to just be natural and focus on building the relationship."
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So in my mind, aiming for a world where you can live where your family is, where your friends are, AND continue to do great work is…
That’s what we should be aiming for, and why I get so excited about these up-and-coming regions.
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Apple Podcasts & Spotify links in the comments below! 👇🏽
Apple Podcasts:
Spotify:
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"I did say it's nice to build out your career and get some of the momentum there, but taking the idea of there's no secret to anything to a further extreme, there was nothing stopping me then from doing what I'm doing now."
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Anyone with an iPhone pretty much has as much potential to influence people as ESPN.
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@bitbio
@MarkKotter
It was such a profound conversation, wrapped in the stories of his early schooling and career… I hope it gives you as many “aha” moments as it did for me.
Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
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Geographic density for collaboration and access to local capital are two big ones.
How many of those elements an area has (or can attract) likely plays a large role in how big a hub they have the potential to become.
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@bitbio
@MarkKotter
And for everyone else, I know you’ll be as fascinated as I was listening to Mark’s experiences.
Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
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I feel less “crazy” since starting The Biotech Startups Podcast.
If you’ve been following my posts for any length of time, you’ve probably seen me talking about all my theories of what makes a successful company.
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I’m so excited to share this first part of my conversation with
@FabricNano
Co-Founder and CEO, Grant Aarons.
There’s so many reasons:
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@NoamSolomon1
@Immunaitech
This episode is packed with insights that challenge common perceptions about AI in biotech, offering a mathematician's perspective on the field's complexities and potential.
Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
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@MelioraTx
@davidycli
It’s an episode of big dreams, paradigm-shifting goals, and the village it takes to make it happen.
Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
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Where we’re at right now?
Much healthier for a long-term environment.
If you’ve never operated in a more normalized market like this, don’t panic.
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@bitbio
@MarkKotter
Apple Podcasts & Spotify links in the comments below! 👇🏽
#biotechnology
#lifesciences
#podcast
Apple Podcasts:
Spotify:
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