Vizgen
@vizgen_inc
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Confidently take your research to new depths with MERSCOPE Ultra integrating single-cell and spatial multiomics analysis powered by MERFISH technology.
Cambridge, MA
Joined February 2020
Check out our new Google #ColabNotebook available for you to explore the #MERFISH Mouse Liver #DataSet with. It shows how to perform #SingleCellClustering, #SpatialAnalysis, and more! Start exploring today: #SCANPY #UMAP #AlphaShape
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#Colitis is a complex form of #IBD & #MERFISH #SpatialTranscriptomics can be used to study it! Researchers led by Dr. Jeff Moffitt from @BostonChildrens developed a framework for studying inflammation-induced #GutRemodleing in mice.🐭. Read the preprint:
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Check out our new Interactive Single-Cell Spatial Visualizer tool! Explore a #MERFISH spatial plot by selecting a gene of interest, clicking cells to highlight cell clusters, and toggling between #UMAP & spatial views. See #spatial #singlecell #data!
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Our Google #ColabNotebook is one way you can explore the #MERFISH Mouse #Liver #Dataset. It shows how to perform #SingleCellClustering, #SpatialAnalysis, and more! Start exploring today: #MERSCOPE #SCANPY #UMAP #AlphaShape #AcademicTwitter
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A🐭🧠 project spearheaded by @AllenInstitute created a #SpatialTranscriptomic #CellTypeAtlas of the whole #MouseBrain! Many key marker genes used in our new #MERSCOPE PanNeuro Cell Type Panel were validated in this project. Read the paper & learn more:
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🐭A beautiful study from @JoeEcker's Lab at @salkinstitute was included in the #BICCAN series published in @Nature! They used #MERFISH on #MERSCOPE to create the 1st brain-wide, single-cell resolution DNA methylome & 3D #MultiomicAtlas of the #MouseBrain:
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We're excited to announce the launch of the #MERSCOPE PanNeuro Cell Type Mouse 500 Gene Panel- Vizgen's first #PredesignedPanel, enabling cellular and sub-cellular analysis of neuronal signaling, activity and connectivity in the #mousebrain!.
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New #MERFISH publication alert! Dr. Xiaowei Zhuang's @Harvard research team developed #EpigenomicMERFISH! Check out the open access publication available from @CellCellPress: #Fascinating #Epigenomics #MERFISH #Brilliant
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#30DayMapChallenge Day 27- #Heatmap.#MERFISH mouse brain map. The interactive heatmap enables the visualization of gene expression across Leiden clusters and single-cells!.#observable_jupyter #deckgl #spatialtranscriptomics @googlecolab @observablehq
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The first data release of the Vizgen Data Release Program is now available! The MERFISH Mouse Brain Receptor Map is a high-resolution spatial map of GPCR and RTK expression within the mouse brain. Explore the data #openaccess #spatialgenomics #neuroscience
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We are elated to share this pre-print from collaborators at @AllenInstitute @Penn @genentech & @Harvard! Here they demonstrate the construction of a transcriptomic & spatial cell type atlas of a mouse brain using the #MERSCOPE Platform powered by #MERFISH.
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🔬Unlocking the secrets of the heart! Researchers from @UCSanDiego have developed a detailed 3-D atlas of the human heart using MERFISH technology! Read the full research publication #MERFISH #SpatialGenomics #CardiacResearch
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Exciting news! 📢 A new #Python toolkit #Monkeybread was built by @ImmunitasTx to analyze cellular niches in #SingleCell spatial data & applied it to our #MERSCOPE #FFPE Human #ImmunoOncology #Melanoma tumor #MERFISH dataset.🐵🍞. Check out the #Preprint:
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We are excited to unveil the first combined #singlecell and #spatial #genomics platform for imaging cells & tissues with single-molecule sensitivity, nanometer-scale resolution, and high multiplexing power! Learn more at our talk tomorrow at 2:30PM @agbt
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📣We are excited to share a preprint from our brilliant scientific co-founder Dr. Xiaowei Zhuang's lab at @Harvard! . Meng Zhang's amazing team used #MERFISH to create a #CellAtlas of the whole mouse brain- .🐭🧠👩🔬. #IWD2023 #EmbraceEquity #WomenInScience
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New preprint from @ozgungokce's lab at the Institute for Stroke and Dementia Research, LMU@ISD_Research! His team developed Spatial Transcriptomics-correlated Electron Microscopy (#STcEM) using #MERFISH data generated by #MERSCOPE. Preprint on BioRxiv:
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🚨 Südhof & Quake Labs at @czbiohub created a spatial map of a long-term memory engram with #MERSCOPE! With #MERFISH they found persistent memory-associated transcriptional signatures in neurons & astrocytes in mice. Read the preprint: 🐭🧠. #NeuroTwitter
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Did you hear the news? #SpatialTranscriptomics was featured in publications throughout 'Best of Cell 2022'! This special edition of @CellCellPress includes impactful publications from across the #LifeSciences. Check it out today: #ThrowbackTHursday
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We're excited to share a new #Publication by researchers at @czbiohub featuring our #MERSCOPE Platform! They compared #MERFISH #SpatialTranscriptomics data from mouse liver & kidney tissue against bulk #RNAseq & #scRNAseq. Read it on .@biorxivpreprint!
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The #MERFISH #MouseBrain Receptor Map is one of the many resources we used to make the gene list our new #MERSCOPE PanNeuro #CellType #PredesignedPanel. Explore our #SpatialTranscriptomics data & insights: 🧠🐭. #Neuroscience #CellAtlas #MolecularAtlas
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Another cool study from Ecker Lab @salkinstitute! By integrating scDNA methylome & #MERFISH datasets generated by #MERSCOPE, researchers created the 1st brain-wide, single-cell resolution DNA methylome & 3D multiomic atlas of #MouseBrain.🐭🧠. Learn more:
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We're excited to share a new preprint from the @AllenInstitute using #MERSCOPE to make a comprehensive high-resolution multimodal #CellAtlas of #AlzheimersDisease in #humanbrain!👏. Read the preprint to learn more: #MERFISH #SpatialGenomics #Neurotwitter
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New #PublicationAlert for #MERFISHtechnology from the lab of Dr. Xiaowei Zhuang at @Harvard! Fang et al used #MERFISH to image 4000 genes in human brain tissue & introduced a method to reduce autofluorescence background!.Read it on @ScienceMagazine:
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#MERSCOPE experiments create a vast amount of #SpatialData! Stop by our #SciPy2023 poster tonight at 6PM CDT to learn about our #CORMERANTlibrary that helps researchers navigate complex #MERFISH datasets. Learn more: #SCANPY #Squidpy @scverse_team
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We're proud to share that a new #publication by the Human Breast Cell Atlas Network lead by @nicholas_navin from @MDAndersonNews featuring #MERSCOPE data is available in @Nature!. Learn more about the #CellAtlas of the adult human breast: #HumanCellAtlas
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🔍Trying to figure out what high-quality #SpatialGenomics data looks like? Not all spatial genomics platforms are created equal so download our new #eBook to explore 4 key #QualityMetrics to help scientists distinguish high-quality spatial genomics data:.
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MERSCOPE integrates high-resolution imaging, fluidics, & image processing into automated hardware to deliver precise #MERFISH measurements. Sub-cellular resolution down to 100nm and unparalleled sensitivity enabling the detection of ~70% more #transcripts, what can you discover?
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Check it out! @AllenInstitute's Whole Mouse Brain Atlas detailed in @Nature leveraged #MERFISH on #MERSCOPE to create a high-res spatial transcriptomic atlas the #MouseBrain.🐭🧠. Read the publication today: #AcademicTwitter #Neuroscience #MouseBrainAtlas
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🚨#ICYMI we launched our 1st #PredesignedPanel for #MERSCOPE! Download our #ApplicationNote to learn how we developed & validated the new 500 gene PanNeuro Mouse Cell Type Panel: 🐭🧠. #MERFISH #Neuroscience #BrainScience #MouseBrain #CellAtlas #CellType
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We used our #MERFISH #MouseBrain Receptor Map to help created the #MERSCOPE PanNeuro #CellType #PredesignedPanel gene list.🐭. You can explore the dataset today! #SpatialTranscriptomics #Neuroscience #CellAtlas #MolecularAtlas #NeuroTwitter #BrainScience
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We love learning about new #ComputationalTools for analyzing #SpatialData! MENDER is a novel tissue structure identification tool utilizing cellular neighborhood structures observed across spatial technologies now published in @NatureComms. Learn more:.
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A wonderful talk last night by Dr. Xiaowei Zhuang @Harvard at the @CellSymposia: The Conceptual Power of Single Cell Biology! #MERFISH #CSSingleCells23
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We're thrilled to share that Vizgen closed $85.2 million in #SeriesC financing! This funding will enable our team to deliver more #MERSCOPE Platforms to labs around the world. Read the full #PressRelease: #TeamworkMakesTheDreamWork
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Get ready to enter the #SpatialDimension with the #MERSCOPE Web Vizualizer! With our new tool, you can easily interact with the full output of a MERSCOPE experiment. Visit our website to explore our #MERFISH Mouse Liver Map- #ComputationalBiology
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New publication featuring data generated by the early access #MERSCOPE Platform at @SCOPE_UMMS. Researchers from @UMassChan, @broadinstitute, @Stanford, @Harvard, and @MassGeneralNews used #MERFISH data to study the mouse #OlfactoryBulb 🐁👃 @NatureNeuro:
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Check out this landscape! We detected over 500 million total transcripts in the #MERFISH Mouse Brain Receptor Map using our MERSCOPE Platform. Visit our website to explore the full dataset! #spatialtranscriptomics #MERSCOPE #NaturePhotographyDay #SciArt
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Spring into spatial with our Data Release program! Explore the full outputs of our open-access #MERFISH experiments from #MERSCOPE:. 👩🔬FFPE Human Immuno-oncology.🐭Mouse Liver Map.🧠Mouse Brain Receptor Map. Which dataset will you to go #MERFISHing with?.
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📣We're excited to share that a #LiverCancer study from @MiriamMerad's Lab at @IcahnMountSinai featuring #MERSCOPE Platform #SpatialTranscriptomics data has been published in the June edition of @NatureMedicine!. Read the #PressRelease to learn more:
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Interested in #Bioinformatics and #SpatialAnalysis? Check out this #preprint!. Klein et al developed a new framework to map single cells across time and space called #moscot & use the #MERFISH #MERSCOPE #Mouse #Liver & #Brain #datasets: #AcademicTwitter
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#SpatialGenomics equips scientists with the high resolution and sensitivity of data needed to uncover new insights into health & disease, but how?. Find out in our CEO Terry Lo's article in @EBRmagazine: #DataQuality #BiologicalAccuracy #MERFISH
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We are excited to announce the launch of MERSCOPE Protein Co-detection Kits, enabling subcellular spatial #multiomics measurement with the simultaneous detection of RNA and proteins during a MERFISH experiment. Learn more: #MERSCOPE #SpatialGenomics
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New #MERFISH Publication! Researchers from @Harvard and @AllenInstitute posted a new article to @biorxivpreprint showcasing a #SpatiallyResolved #CellAtlas of the middle and superior temporal gyrus regions of the #HumanBrain created with MERFISH. Read it!.
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Can your single-cell data do this? Learn how your lab can achieve true in situ single-cell spatial genomics with #MERFISH measurements from the #MERSCOPE Platform: #LetsGoMERFISHing #SummerOfSpatialGenomics #BiologyIsCool
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The first commercial MERSCOPE Platforms have shipped! The first platforms are at leading research institutes @salkinstitute, @UCIrvine & @BIDMChealth. Explore new dimensions through spatial context with MERSCOPE! Learn more: #spatialgenomics #MERFISH
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#ICYMI- @HongkuiZeng, Director, @AllenInstitute for #BrainScience, published a beautiful review in @CellCellPress that reflects her dedication to unraveling the secrets of cells. Read it today: #AcademicTwitter #CellBiology #CellType.
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We have released our commercial MERSCOPE Platform! We are excited that researchers at @salkinstitute, @UCIrvine and @BIDMChealth can now use #MERSCOPE for #MERFISH to access the spatial dimension & make new discoveries. Read the release: #spatialgenomics
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Check out this article by researchers from @JohnsHopkins! They used #MERFISH data to help develop STdeconvolve, a reference-free, unsupervised computational method for estimating the proportions of different cell types in #SpatialTranscriptomics data:
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🚨 Check out this @NatureBiotech review highlighting the expanding landscape of spatial transcriptomics approaches by Luyi Tian, Fei Chen and Evan Macosko from @broadinstitute #SpatialTranscriptomics #SpatialGenomics #MERFISH.
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👏We're excited to share that a series of @Nature studies harnessing the power of #MERFISH technology to build the most comprehensive #CellularMap of the adult #MouseBrain is available! . Learn more: #PressRelease #AcademicTwitter #NeuroTwitter #MERSCOPE
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MERFISH publication alert in @Nature! Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH by Zhang et al. #openaccess #singlecell #cellatlas
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@ozgungokce's lab developed Spatial Transcriptomics-correlated Electron Microscopy (#STcEM) using #MERFISH data generated by the Vizgen #LabServices team with #MERSCOPE. Learn more: 🐭🧠.#SpatialTranscriptomics #Neuroscience #MouseBrain #AcademicTwitter
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📣We're excited to share that the research by @czbiohub featuring data generated by #MERSCOPE has been published in @LSAjournal! Read the #publication to learn how #MERFISH #SpatialTranscriptomics data compares against bulk #RNAseq & #scRNAseq:
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The MERSCOPE Platform has landed at @LMU_Muenchen in Germany! Happy MERfishing to @ozgungokce and team! Big thanks to @steven_harbert, Miles and Andrew for another successful install! #spatialgenomics #MERFISH
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🎉 Groundbreaking publication from @vizgen_inc co-founder @MoffittLab #MERFISH has already provided incredible insights into eukaryotic systems, but until now, bacterial mRNAs have posed a significant challenge due to their density (1/3). #BacterialMERFISH
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Read how @HumphreysLab is benefiting from @vizgen_inc's #singlecell #spatial #transcriptomics technology to advance research into kidney injury for developing new approaches to treating kidney disease. #NationalKidneyMonth #AGBT21 #KidneyDisease
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Scientists from @AllenInstitute have achieved a groundbreaking milestone in #Neuroscience: A comprehensive, cell-by-cell map of the entire mouse brain! Explore what this means for future research in this @TheScientistLLC article #MouseBrain #BrainResearch
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Get ready to go beyond #SingleCell data & #EnterTheSpatialDimension with @vizgen_inc's Single-Cell Spatial Visualizer tool! Explore how cells profiled from a #MERSCOPE experiment are identified & mapped back to their spatial coordinates in the tissue-
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Download our latest poster to learn about our #CORMERANTlibrary, an open-source #PythonLibrary, that enables you to perform #Singlecell and #SpatialAnalysis of #MERSCOPE #MERFISH data in the context of a #Jupyter notebook. Get it here👉 👩🔬💻🎣.
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Dear Friends of Vizgen,. At Vizgen, we believe that researchers should have the ability to choose the best technologies for their labs. We in invite you read an Open Letter from Terry Lo, our President & CEO regarding recent announcements from Europe:
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📣Congratulations to @ozgungokce on his appointment as the Head of Systems Neuroscience – Cell Diversity Research Group, @UniklinikBonn!👏. His lab uses #ElectronMicroscopy & #MERSCOPE #MERFISH data to study in aging & #Neurodegeneration. Learn more:
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Spatially Resolved Transcriptomics was named the Method of the Year 2020 by @naturemethods and @vizgen_inc would like to recognize some MERFISH pioneers in this field @DulacLab @RiceLaboratory @broadinstitute @humancellatlas @SStevenWang @roy_wollman @JEFworks @JiangHe34553644 🔬
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#PublicationAlert for #MERFISH technology! Researchers from @Harvard used MERFISH to intricately map transcriptional & behavioral features in individual cells of mouse periaqueductal gray matter. Read it on: @biorxivpreprint: #MERFISH #NeuroTwitter
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#30DayMapChallenge Day 30- #Metamapping .Mouse Brain #SpatialTranscriptomics generated with #MERSCOPE. The map shows the expression of 6 genes from a 483 gene #MERFISH panel run on mouse brain tissue. Interact with our #MERFISH data! #deckgl @observablehq
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In June, a joint team of researchers from @Yale # the Southern Medical University in Guangzhou published a paper in @NaturePortfolio's #CellDiscovery about using #MERFISH to spatially profile the #transcriptome of the mouse fetal liver HSC Read it today!
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We are excited to share that the first AUS #MERSCOPE platform has been installed at @WEHI_research last week. Happy MERfishing! #SpatialGenomics #MERFSISH
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We’ve seen great excitement surrounding our instrument, but this is just the beginning. We are working with our customers to bring new platform capabilities & applications throughout the year & continue to lead this new era of spatial genomics.” Terry Lo President & CEO of Vizgen
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📢Vizgen Announces Major Patent Milestone for Spatial Genomics! 🧬✨ The US Patent Office has officially granted Vizgen, Inc., U.S. Patent No. 11,959,075, paving the way for innovation in the spatial transcriptomics realm. Learn more: #MERFISH
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📣There has been a lot of noise about #benchmarking #SpatialTranscriptomics technologies. Read the new independent study by @nygenome's Austin Hartman & @satijalab to learn how #MERSCOPE outperforms other methods: #Vizgen #MERFISH #AcademicTwitter
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#SpatialTranscriptomics is used across many biological application areas like #KidneyResearch! The review by the @HumphreysLab at @WUSTLmed #Nephrology compares SrT technologies such as #MERFISH & explores what each has to offer #Kidney researchers:
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🎉We're excited to share that #Vizgen placed number 1 on @GENbio's top private spatial biology company list for 2023!. Read the article today👉 #MERSCOPE #MERFISH #SpatialBiology #SpatialGenomics #SpatialTranscriptomics #SpatialMultiomics
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Friday, March 4th is the sixth annual #SingleCell #Genomics Day hosted by @satijalab! Attend the free virtual workshop to learn about new developments in the field and watch presentations on novel single-cell genomics methods. Learn more about:
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MERFISH is a novel imaging technology for single-cell genomics with broad applications from basic science, to drug discovery, to clinical pathology. Each image is taken with 100nm resolution across whole tissues or single cells #spatialgenomics #singlecell #transcriptomics
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Start the new year in #HighResolution with #MERSCOPE, the premier platform for #InSitu #SingleCell #SpatialGenomics!. #MERFISH + MERSCOPE Optimized Optics = more #RNA transcripts detect & higher #InformationDensity. Download our eBook to learn more:
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#Vizgen today announced the denial of 10x Genomics' petition for inter partes review of Vizgen-licensed patent currently asserted against 10x Xenium Platform. Read the release: .#SpatialGenomics.
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#TGIF! Want something fun to do today? Use our #MERSCOPE Web Vizualizer to take a tour of the #MERFISH #Mouse #BrainMap and explore spatial gene expression patterns across mouse brain tissue! Click here: .🐭🧠💻.#NeuroTwitter #AcademicTwitter
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We're excited to announce that our distributor, @BucherBiotec installed our first #MERSCOPE in Europe! Thanks to our FSE Andrew Haworth and our FAS Andrea de Biase, scientists in #Switzerland will be generating beautiful #MERFISH data- #HappyMERfishing! .
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🌟 A new lung cancer study from Nir Hacohen's Lab shows 'immunity hubs' can inform PD-1 therapy success. Spotlight on stem-immunity hub for better treatments. #CancerResearch #Immunotherapy #MERSCOPE #Vizgen #SpatialTranscriptomics.
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Our new automated MERSCOPE instrument lets you localize RNA transcripts for up to 500 genes in any sample or tissue type at <100nm subcellular resolution. What will you discover? Learn more: #transcriptomics #spatialgenomics #agbt21
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Need a boost to your #MondyMotivation? Check out our Interactive Single-Cell Spatial Visualizer tool! Explore the #MERFISH Mouse Brain Receptor Map data generated by our #MERSCOPE. #SpatialGenomics #Bioinformatics #ComputationalBiology 💻
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We're excited to share some excellent news, @vizgen_inc has been included on @GENbio's first-ever Top 10 #SpatialBiology Companies! It's an honor to be recognized for our commitment to #MERFISH & #MERSCOPE. A shout out to Yoni Bock for being featured! -
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📣We're excited to share the 1st application of #MERSCOPE #SpatialTranscriptomics in #PlantBiology!🌱. This study by Ecker Lab at @salkinstitute used #MERFISH data to create a single-nucleus atlas of seed-to-deed development in Arabidopsis. Learn more:
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We're excited to share a new tutorial walking users through the @ProjectJupyter Colab Notebook on #GoogleCloud with @vizgen_inc's #MERFISH Mouse Brain Receptor Map #openscience #dataset! #SingleCell #SpatialGenomics #DeckGL #observable #jupyter #SCANPY
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#SpatialTranscriptomics methods like #MERFISH enable researchers to investigate gene expression patterns across tissues. SPADE is a new #DataAnalysis tool developed by researchers at @UofSC & @UF that identifies spatially variables genes. Learn more:
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Did you miss day 1 of #SpatialBiology Online from @FLGenomics?. Read the publication from @ozgungokce's lab in @NatureComms & learn about #SpatialTranscriptomics correlated #ElectronMicroscopy! 🐭🧠. Learn about #STcEM: #MERFISH #MERSCOPE #LabServices
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👏We're excited to see four #BICCN papers leveraging the #MERSCOPE Platform featured in @ScienceMagazine's Brain Cell Census collection!. 🎣Catch the papers today- #MERFISH #AcademicTwitter #NeuroTwitter #Neuroscience #BrainScience.
In 21 papers across Science, @ScienceAdvances, and @ScienceTM, researchers with the #BICCN consortium present an atlas of the human and nonhuman primate brain in unprecedented detail. The results uncover the genetic organization of the human brain.
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🧠Looking for some brainy fun this week? Check out the original #MERSCOPE #MERFISH Mouse Brain Receptor Map!🐭. -483 gene panel.-734,969 total cells imaged.-554,802,908 total transcripts detected.-GPCRs & RTKs. Explore today: �. #BrainWeek #NeuroTwitter
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🚀 Breaking news at #AACR2024! Introducing MERSCOPE® Ultra & MERFISH 2.0 Chemistry - a revolution in single-cell #SpatialTranscriptomics. Dive into how these breakthroughs are reshaping basic & translational research. 🔗 #MERSCOPEUltra #SpatialGenomics
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Accuracy & sensitivity are critical for generating meaningful #SpatialGenomics data! Our latest #DataRelease shows the high #Reproducibility of #RNA & #ProteinCoDdetection with the #MERSCOPE #FFPE Sample Prep Solution & Protein Stain Kits. Learn more:
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#SpatialGenomics data is only useful if you have the right tools to make sense of it!. The #MERSCOPEvizualizer enables you to interact, analyze & interpret even the most complex #MERFISH datasets generated by #MERSCOPE. Visit our website to learn more:
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The insights shared in the open letter to Genetic Engineering & Biotechnology News have ignited crucial conversations about the nature of scientific advancement and the role of diverse methodologies, perspectives, and tools in this journey.
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Join the @satijalab for the 7th annual #SingleCellGenomicsDay on Friday, March 29, 2024 to explore cutting-edge #singlecell #genomics technologies, computational approaches, & hear keynote presentations. Free livestream available!. Find out more:
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Our next #MERFISH data set is coming soon! . The #MERSCOPE #FFPE #ImmunoOncology Data Release will feature MERFISH measurements of 8 different FFPE human tumors using a panel of 500 genes. Sign up today to be alerted when the data set is released:
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We're excited to be presenting a virtual poster at #VIZBI2022! Nicolas Fernandez @franschrandez will present our @GoogleColab notebook and Web Viz using @vizgen_inc's #MERFISH Mouse Liver Map #OpenAccess #DataSet. View our poster:
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The Vizgen Data Release Program will give researchers early access to MERSCOPE datasets to enhance their research & better understand the unique advantages of subcellular resolution & high detection efficiency. Sign-up today, the first is coming soon!
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👀By studying the spatial organization of the #Retina with #MERSCOPE #SpatialTranscriptomics, scientists can better understand retina function & eye diseases. Learn about the spatial organization of the #MouseRetina from Dr. Rui Chen's lab at @bcmhouston:
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Customize your #CellSegmentation with the new #Cellpose2 Plugin for the #Vizgen Post-Processing Tool! . Visit our website to learn how you can improve segmentation results for challenging tissues with the plugin for #VPT:. #MERSCOPE #MERFISH #Spatialomics
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Did you know that #MERFISH can help you understand the nuances of #GeneExpression? Read our latest article in @GENbio to learn how #MERSCOPE harnesses this awesome #SpatialTranscritpomics technology: #NeuroTwitter #CancerTwitter
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