Check out our new Interactive Single-Cell Spatial Visualizer tool! Explore a
#MERFISH
spatial plot by selecting a gene of interest, clicking cells to highlight cell clusters, and toggling between
#UMAP
& spatial views. See
#spatial
#singlecell
#data
!
We're excited to announce the launch of the
#MERSCOPE
PanNeuro Cell Type Mouse 500 Gene Panel- Vizgen's first
#PredesignedPanel
, enabling cellular and sub-cellular analysis of neuronal signaling, activity and connectivity in the
#mousebrain
!
The first data release of the Vizgen Data Release Program is now available! The MERFISH Mouse Brain Receptor Map is a high-resolution spatial map of GPCR and RTK expression within the mouse brain. Explore the data
#openaccess
#spatialgenomics
#neuroscience
We are excited to unveil the first combined
#singlecell
and
#spatial
#genomics
platform for imaging cells & tissues with single-molecule sensitivity, nanometer-scale resolution, and high multiplexing power! Learn more at our talk tomorrow at 2:30PM
@agbt
New preprint from
@ozgungokce
's lab at the Institute for Stroke and Dementia Research, LMU
@ISD_Research
! His team developed Spatial Transcriptomics-correlated Electron Microscopy (
#STcEM
) using
#MERFISH
data generated by
#MERSCOPE
. Preprint on BioRxiv:
🚨 Südhof & Quake Labs at
@czbiohub
created a spatial map of a long-term memory engram with
#MERSCOPE
! With
#MERFISH
they found persistent memory-associated transcriptional signatures in neurons & astrocytes in mice.
Read the preprint:
🐭🧠
#NeuroTwitter
Another cool study from Ecker Lab
@salkinstitute
! By integrating scDNA methylome &
#MERFISH
datasets generated by
#MERSCOPE
, researchers created the 1st brain-wide, single-cell resolution DNA methylome & 3D multiomic atlas of
#MouseBrain
.🐭🧠
Learn more:
MERSCOPE integrates high-resolution imaging, fluidics, & image processing into automated hardware to deliver precise
#MERFISH
measurements. Sub-cellular resolution down to 100nm and unparalleled sensitivity enabling the detection of ~70% more
#transcripts
, what can you discover?
🔍Trying to figure out what high-quality
#SpatialGenomics
data looks like? Not all spatial genomics platforms are created equal so download our new
#eBook
to explore 4 key
#QualityMetrics
to help scientists distinguish high-quality spatial genomics data:
We love learning about new
#ComputationalTools
for analyzing
#SpatialData
! MENDER is a novel tissue structure identification tool utilizing cellular neighborhood structures observed across spatial technologies now published in
@NatureComms
.
Learn more:
Spring into spatial with our Data Release program! Explore the full outputs of our open-access
#MERFISH
experiments from
#MERSCOPE
:
👩🔬FFPE Human Immuno-oncology
🐭Mouse Liver Map
🧠Mouse Brain Receptor Map
Which dataset will you to go
#MERFISHing
with?
We are excited to announce the launch of MERSCOPE Protein Co-detection Kits, enabling subcellular spatial
#multiomics
measurement with the simultaneous detection of RNA and proteins during a MERFISH experiment. Learn more:
#MERSCOPE
#SpatialGenomics
Check out this article by researchers from
@JohnsHopkins
! They used
#MERFISH
data to help develop STdeconvolve, a reference-free, unsupervised computational method for estimating the proportions of different cell types in
#SpatialTranscriptomics
data:
🎉 Groundbreaking publication from
@vizgen_inc
co-founder
@MoffittLab
#MERFISH
has already provided incredible insights into eukaryotic systems, but until now, bacterial mRNAs have posed a significant challenge due to their density (1/3).
#BacterialMERFISH
Dear Friends of Vizgen,
At Vizgen, we believe that researchers should have the ability to choose the best technologies for their labs. We in invite you read an Open Letter from Terry Lo, our President & CEO regarding recent announcements from Europe:
We’ve seen great excitement surrounding our instrument, but this is just the beginning. We are working with our customers to bring new platform capabilities & applications throughout the year & continue to lead this new era of spatial genomics.” Terry Lo President & CEO of Vizgen
📢Vizgen Announces Major Patent Milestone for Spatial Genomics! 🧬✨ The US Patent Office has officially granted Vizgen, Inc., U.S. Patent No. 11,959,075, paving the way for innovation in the spatial transcriptomics realm. Learn more:
#MERFISH
MERFISH is a novel imaging technology for single-cell genomics with broad applications from basic science, to drug discovery, to clinical pathology. Each image is taken with 100nm resolution across whole tissues or single cells
#spatialgenomics
#singlecell
#transcriptomics
Friday, March 4th is the sixth annual
#SingleCell
#Genomics
Day hosted by
@satijalab
! Attend the free virtual workshop to learn about new developments in the field and watch presentations on novel single-cell genomics methods. Learn more about:
MERFISH has allowed scientists to visualize gene expression like never before – but we're not stopping there! We're unveiling some big news on March 2 at
@AGBT
. Tune in to the conference and watch our social channels to glimpse the future of spatial
#genomics
.
#AGBT21
#Vizgen
today announced the denial of 10x Genomics' petition for inter partes review of Vizgen-licensed patent currently asserted against 10x Xenium Platform. Read the release:
#SpatialGenomics
Our new automated MERSCOPE instrument lets you localize RNA transcripts for up to 500 genes in any sample or tissue type at <100nm subcellular resolution. What will you discover? Learn more:
#transcriptomics
#spatialgenomics
#agbt21
We're excited to share some excellent news,
@vizgen_inc
has been included on
@GENbio
's first-ever Top 10
#SpatialBiology
Companies! It's an honor to be recognized for our commitment to
#MERFISH
&
#MERSCOPE
. A shout out to Yoni Bock for being featured! -
#FFPE
preservation maintains
#TissueMorphology
, but the
#RNA
in these samples usually exhibits degradation. 🙁
Download our app note to learn how the
#MERSCOPE
#FFPE
Sample Preparation Workflow ensures you get great
#MERFISH
data from FFPE samples: 😀
🧠Looking for some brainy fun this week? Check out the original
#MERSCOPE
#MERFISH
Mouse Brain Receptor Map!🐭
-483 gene panel
-734,969 total cells imaged
-554,802,908 total transcripts detected
-GPCRs & RTKs
Explore today: 🎣
#BrainWeek
#NeuroTwitter
#SpatialGenomics
data is only useful if you have the right tools to make sense of it!
The
#MERSCOPEvizualizer
enables you to interact, analyze & interpret even the most complex
#MERFISH
datasets generated by
#MERSCOPE
.
Visit our website to learn more:
In 21 papers across Science,
@ScienceAdvances
, and
@ScienceTM
, researchers with the
#BICCN
consortium present an atlas of the human and nonhuman primate brain in unprecedented detail.
The results uncover the genetic organization of the human brain.
Our next
#MERFISH
data set is coming soon!
The
#MERSCOPE
#FFPE
#ImmunoOncology
Data Release will feature MERFISH measurements of 8 different FFPE human tumors using a panel of 500 genes.
Sign up today to be alerted when the data set is released:
Join the
@satijalab
for the 7th annual
#SingleCellGenomicsDay
on Friday, March 29, 2024 to explore cutting-edge
#singlecell
#genomics
technologies, computational approaches, & hear keynote presentations. Free livestream available!
Find out more:
The Vizgen Data Release Program will give researchers early access to MERSCOPE datasets to enhance their research & better understand the unique advantages of subcellular resolution & high detection efficiency. Sign-up today, the first is coming soon!
The insights shared in the open letter to Genetic Engineering & Biotechnology News have ignited crucial conversations about the nature of scientific advancement and the role of diverse methodologies, perspectives, and tools in this journey.
The Vizgen Data Release Program gives researchers early access to MERSCOPE data to enhance their research & better understand the unique advantages MERFISH technology. Sign up today to be alerted when data sets are released!
#transcriptomics
#research
Scientists in
#Boston
posted an article to
@biorxivpreprint
showing a new statistical method called
#GLAMDE
that detangles the differential gene expression between overlapping cells! Which tissue you would look forward to applying
#MERFISH
and
#GLAMDE
to?