#BREAKINGNEWS
Sherlock Biosciences makes history for first ever
#FDA
authorized use of
#CRISPR
technology. Emergency Use Authorization granted for test kits which use the SHERLOCK™ CRISPR-based method to rapidly identify the virus that causes
#COVID19
We have secured $80 million in
#SeriesB
financing led by Novalis LifeSciences.
This milestone advances our mission to break down diagnostic barriers and bring health information to people at the point-of-need.
Learn more here:
#CRISPR
We're thrilled that our team's work on the INSPECTR assay developed in partnership with
@wyssinstitute
researchers is now published in
@NatureBiotech
. This novel molecular diagnostic enables highly-accurate detection of pathogens at the point of need.
Study by
@pardissabeti
in
@Nature
:
#CRISPR
diagnostics proven to perform thousands of tests simultaneously on over 100 targets, including
#COVID19
. By screening large sample sets for many pathogens at once, broader detection enables deeper insight.
Our co-founder Jim Collins’ lab adapted our namesake technology to detect SARS-CoV-2, designing an easy-to-use diagnostic device that can use saliva samples to give a result for
#COVID
within an hour.
Read more in
@GENbio
and watch the video of the prototype from
@wyssinstitute
#COVID19
Test Detects Emerging Variants Using SHERLOCK and Saliva
Engineers at
@MIT
and
@harvardmed
have designed a test that can detect
#SARSCoV2
from a saliva sample in about an hour with the same accuracy as the
#PCR
tests now used. Learn more:
#CRISPR
Congratulations to our Co-founder
@zhangf
on
#1
in
@NatureBiotech
's Top 20 translational researchers of 2020 and to our Co-founder &
@wyssinstitute
faculty member Jim Collins on being named to
@clarivate
's 2021 Highly cited Researchers list!
Congratulations,
@wyssinstitute
for bringing innovation out of the lab and into the real world to fight
#COVID19
. Thank you for including us and our collaboration with
@IDTDNA
in the start-up spotlight for 2020’s “Impact In The Age Of Coronavirus” Report.
What if we could design a face mask that changes color when the coronavirus is detected in the wearer? With the help of synthetic biology, that's exactly what this team of scientists is creating.
Watch Jim Collins's full talk here:
The Bill & Melinda
@GatesFoundation
has awarded us a $5 million grant to advance our
#synbio
INSPECTR™ platform for instrument-free
#COVID19
#diagnostics
to support our promise of delivering testing anywhere, including low- and middle-income countries.
We are
#hiring
a Principal Scientist - Assay Development to work with our molecular and engineering teams to develop next generation diagnostics on our CRISPR and Synthetic Biology technology platforms.
Join our Team!
#CareersinSTEM
#AssayDevelopment
Boston
@NPR
affiliate
@WBUR
visited our offices to learn about our mission to develop quick, cheap, & accurate
#COVID
tests for home, school, or other places where fast & easy testing is needed. Learn about our progress and hope for the future.
Since co-inventing our SHERLOCK
#CRISPR
platform, our co-founder Jim Collins led a team to apply the 2018 one-pot, ultrasensitive
#diagnostic
method to Malaria, working towards the
@WHO
goal to eradicate this serious and sometimes fatal disease.
A research collaboration led by James Collins’ team at the Wyss has created a CRISPR-based molecular detection assay that could help the diagnostic bottleneck in the global fight against
#malaria
.
#CRISPR
Sherlock Biosciences has been selected as a World Economic Forum 2020 Technology Pioneer. Learn about the
@WEF
#techpioneers20
firms shaping the future by advancing technologies.
Thank you to
@wyssinstitute
for enabling us to bring innovation out of the lab and into the real world to fight
#COVID19
. Read the Year in Review 2020 to learn more about this year’s impact on the future.
2020 was quite a year for all of us - here at the Wyss, we published over 200 papers, obtained 48 patents, launched 11 startups, licensed COVID-19-related tech to 6 companies, and more. Check out the rest of our 2020 highlights here!
Another exciting innovation for SHERLOCK from our co-founder Jim Collins' lab
@wyssinstitute
. The miSHERLOCK device uses saliva to test for
#COVID19
and variants with minimal instrumentation, providing at-home results in 1 hour.
Diagnosing the Delta variant could be as easy as spitting: a new device from the Wyss and
@MIT
detects SARS-CoV-2 variants in users' saliva in about an hour, no lab equipment needed.
#COVID19
#Diagnostics
#DeltaVariant
Proud and excited to announce The 221b Foundation, a non-profit organization committed to providing access to
#CRISPR
#diagnostic
tech to end the
#COVID19
pandemic with profits supporting diversity in STEM with
@Scratch
@ScratchEdTeam
.
Thank you
@StraitonJenny
for including us in this important piece on the need for scalable, rapid COVID-19 testing and for highlighting our efforts to bring our point-of-care
#CRISPR
#diagnostic
INSPECTR technology into the home to combat
#COVID19
.
.
@omarabudayyeh
&
@jgooten
found therapeutic potential for a new CRISPR System! Their work with fellow co-founders Deborah T. Hung, James Collins,
@PardisSabeti
,
@zhangf
on the SHERLOCK method demonstrated CRISPR's power in
#diagnostics
. Great to see CRISPR innovation continue!
Excited to share work on a new CRISPR enzyme, Cas7-11, that targets RNA and redefines how we think about CRISPR systems, out now in
@Nature
. Newest CRISPR tool among others like Cas9, Cas12, and Cas13. No official relation to
@7eleven
. W/
@jgooten
Read: 1/n
We’ve reached unicorn status through a successful $195 million series C/D raise!
This financing and our extremely talented team will supercharge our protein discovery engine and accelerate the creation of next-generation
#CRISPR
products.
Read the latest publication from our co-founder Jim Collins' and a team of scientists from
@wyssinstitute
&
@MIT
in
@ScienceAdvances
about miSHERLOCK, a simple, low-cost CRISPR-based diagnostic for
#COVID19
that uses saliva & provides results in one hour.
Congratulations to the Sherlock team members and our partners at
@DartmouthHitch
who contributed to the clinical validation study, "High-Throughput CRISPR-Cas13 SARS-CoV-2" published in
@Clin_Chem_AACC
Read more:
Great to see our co-founder Dr.
@PardisSabeti
featured in the Blue Cross MA
@BCBSMA
“Heroes on the front line” series for her work in
#COVID
research! “We're deep in it,” she says. “It’s a race against time.”
“Synthetic biology is going to become one of the dominant technologies for this century and will be harnessed to address some of our biggest challenges.” Our co-founder Jim Collins discusses
@Sherlock_bio
&
#AI
's power w/
@LynnThoman
on
@3_Takeaways
.
In 2021, we are focused on our 221b Foundation commitments to equity in science, medicine and society; the eradication of
#COVID19
; and the increased inclusion of underrepresented communities in STEM.
Learn more:
With the vaccine rollout underway, widespread surveillance testing remains important tool to stop
#COVID19
spread says
@MPVann
@abcnews
. We are advancing our INSPECTR platform to bring low-cost, instrument-free, self-
#diagnostic
tests to the world.
#synbio
"It’s undoubtedly unusual for a startup..." writes
@BosBizAllison
in
@bosbizjournal
about The 221b Foundation, our non-profit that will direct funds from our
#COVID19
products to programs that support racial and gender
#equity
in
#STEM
. ($)
Today we take an exciting step to democratize & decentralize
#diagnostics
. With our
#acquisition
of
@sensedx1
, we will accelerate the development of powerful molecular
#diagnostics
to transform healthcare and empower consumers around the world.
#Biotech
Our CEO
@BryanDechairo
spoke with
@GrinsteinJ
for his story in
@GENbio
, Sherlock Biosciences Is Cracking At-Home and Field Diagnostics.
Read about the
#CRISPR
advancements our team has made to bring our tests to the point-of-need:
Congratulations to BE GREATEST Award winner,
@adsilverman627
! Adam is recognized by his team for going above & beyond in his role as Chemical Safety Officer in our new headquarters.
Are you driven to
#BEGREAT
& bring out the best in your team?
Join us:
In
@NatureBiotech
, our Co-founder Jim Collins explored the power of
#CRISPR
to drive innovation in decentralized
#diagnostics
.
At Sherlock, we are harnessing CRISPR to improve the sensitivity & specificity of diagnostic tests for the point of need.
Our CEO
@rahulkdhanda
recently spoke with Karen Tkach Tuzman
@_Ktktktktk
@BioCentury
about mass asymptomatic screening for
#COVID19
. His take: "[It's] more valuable if it's used more broadly." Read more:
This new programmable platform from our co-founder Jim Collins' lab at
@wyssinstitute
uses synthetic biology & CRISPR-based SHERLOCK sensors that can be embedded into masks and clothing to detect toxins & pathogens.
What if your face mask could tell you if you have
#COVID19
? Now it can. Researchers from the Wyss and
@MIT
embedded freeze-dried cell-free biological reactions into a face mask, enabling it to detect SARS-CoV-2 in a patient's breath quickly and accurately.
Congratulations to our co-founder
@zhangf
and the entire team at
@arbortx
led by
@devynsmith15
on securing Series B funding to turn CRISPR-based gene editing tools into medicines that can be used in the real world.
Read more by
@jasonMMast
:
High throughput
#CRISPR
#diagnostics
with minimal equipment costs are critical to increasing
#COVID19
testing capacity. We've validated our assay to provide a fast, user-friendly, inexpensive method to detect SARS-CoV-2.
Read our new White Paper here:
Congratulations,
@rahulkdhanda
!
@BosBizJournal
named our CEO in the 2020 Power 50. It’s an honor to be recognized with fellow nominees, who are coming together to rise to the challenges we face and commit to meaningful community impact during this unprecedented time.
#BBJPower50
Thrilled to welcome our new CEO
@BryanDechairo
to Sherlock’s Boston headquarters today! We’re excited to have Bryan helming the ship as we continue our mission to disrupt molecular diagnostics.
Read about our co-founder
@PardisSabeti
innovation using SHERLOCK technology to perform multiplexed nucleic acid testing at scale to prevent future outbreaks in
@JAMA_current
“Virus Surveillance and Diagnosis With a CRISPR-Based Platform”
Large-scale manufacturing of precise rapid-result
#COVID19
tests are critical to fight the
#SARSCoV2
virus. Our webinar with partner
@idtdna
explains how an open-system kit makes our
#CRISPR
diagnostic a game-changer for testing. Register
We are honored to add
@FastCompany
’s Most Innovative Companies for 2021 to our award-winning year. We owe this recognition to our amazing team and their commitment to driving innovation that will transform global health.
#diagnostics
#FCMostInnovative
.
Our co-founders Jim Collins and
@rahulkdhanda
discuss the power of engineering biology to make pragmatic, transformative advances in
#diagnostics
, bringing testing anywhere and everywhere it is needed.
#CRISPR
#synbio
Link to Video:
Simple at-home tests for the coronavirus could be the key to expanding testing and impeding the spread of the pandemic say
@Kotlikoff
@michaelmina_lab
in their
@nytimes
opinion piece.
Widespread
#diagnostic
testing remains vital to detecting and tracking variants and containing the pandemic.
Read "What
#COVID19
testing looks like in the age of vaccines" in
@voxdotcom
by
@SaraMorrison
Real-Time, Multiplexed SHERLOCK for in Vitro Diagnostics, published in
@JMDiagn
, shares our team's use of CRISPR to enable a real-time, single-step nucleic acid detection method for SARS-CoV-2 with a rapid time to result in less than 30 minutes.
Thank you
@FastCompany
for naming our novel
#synbio
platform one of the best innovations in health for The Next Big Thing in Tech Awards! Ambient temp., fully disposable molecular
#diagnostics
have the power to improve human health worldwide.
#FCTechAwards
Our team members' diverse experiences foster ideas & innovation. We strive to
#BeGreat
to make a positive impact on human health.
Meet one of our newest team members, Mary Natoli, Scientist I - Sample Preparation! Here's her vision for our technology.
Join
@HarvardGSAS
alum Jenny Pena today at Harvard's
@thebiotechclub
Career Fair. We’re looking to expand our team of business, technology, disease and industry experts. Interested in helping us build Sherlock and transform public health? Come say hi.
What distinguishes Sherlock CRISPR SARS-CoV-2 from other diagnostic solutions? Register for our partner
@idtdna
's webinar to learn about how
#CRISPR
can improve
#COVID19
testing with speed and precision unlike other available methods.
A round of applause for our team! Your dedication to global health made Sherlock Biosciences one of
@FastCompany
's Most Innovative Biotechnology Companies for 2021.
Read more about our recognition as
#FCMostInnovative
here:
We are thrilled to welcome Tiffany Summerville as our Executive Director, Head of Human Resources. Tiffany shares
@sherlock_bio
’s belief that people are the foundation of our success and will help drive our next phase of growth.
Thank you
@globalergnet
and
@TalDimensions
for naming Sherlock's Magnify Diversity, Equity, Engagement and Inclusion initiative one of the 2022 Top Ten Diversity Action Award winners! Congratulations to our team on earning this recognition for advancing
#DEI
in the workplace!
Pradeep Ramesh is presenting a novel
#DeepLearning
model developed by our
#AI
research group at
@ChEnected
's
#SEED22
#synbio
.
Register to learn how this tool is being leveraged to accelerate next-gen molecular Dx assay development from weeks to hours:
“Managing a team at Sherlock is really a privilege,” says Christine Coticchia. Thinking about your next role? Join Christine and the Sherlock team in meeting the urgent need for diagnostics to transform global health.
Apply today.
In
@GailLdutton
's latest
@GENbio
piece, Synthetic Biology Engineers the Next Genomic Revolution, our co-founder Jim Collins describes how integrating
#AI
and synthetic biology can advance the development of next generation therapeutics and diagnostics.
A pilot study of our CRISPR SARS-CoV-2 test kit performed by Dartmouth-Hitchcock Health
@DartmouthHitch
showed 100% accuracy in real patient samples
#COVID19
.
We've validated our
#CRISPR
#diagnostic
assay to provide a fast, user-friendly, inexpensive method to detect SARS-CoV-2, the virus that causes
#COVID19
.
Read our new White Paper here:
Computational analysis shows our
#diagnostic
test detects
#COVID19
variants. Our CTO Will Blake and Senior Machine Learning Scientist Pradeep Ramesh discuss how we are applying AI and advanced computational tools to respond to new and emerging threats.
#CRISPR
Our Sherlock Biosciences team is achieving GREAT things together and we have an exciting year ahead. Interested in doing groundbreaking work with a team that will support you to be your best? Join us on our mission to transform global public health!
Bringing to market the first
#CRISPR
application approved by the FDA was a proud moment in a challenging 2020! Thank you
@meganmolteni
for highlighting the breakthrough in your
@WIRED
recap of CRISPR’s breakout year.
#diagnostics
2020 was an incredible
#CRISPR
year - CRISPR broke new ground in medicine, saw victories in clinical trials and won the
#nobelprize2020
in Chemistry. These and more are our highlights of 2020.
#crisprmedicine
From CEO
@BryanDechairo
and everyone at Sherlock, we'd like to wish you Happy Holidays — a chance to gather with your loved ones, and a wonderful time to reflect and create new goals and dreams.
#happyholidays
#holidayseason
#holiday
We’re thrilled that Dr. Martin Madaus will be joining Sherlock as the company’s Chief Operations Officer to assist in the rapid expansion of Sherlock in the next 12 months.
Call for
#HBCU
students to explore a
#biotech
career with our team! We've partnered with
@MALifeSciences
to support the next generation of Life Science professionals with a range of internship opportunities.
Apply by 5/16 for Summer and 6/20 for Fall:
"The two-pronged testing strategy — diagnostics and screening — should become the playbook for responding to pandemics."
@cmyeaton
@dylanbgeorge
We are developing INSPECTR, a
#synbio
#diagnostic
test platform to help meet demand for low-cost self-tests everywhere they're needed.
Just out -
@dylanbgeorge
and I write that covid will not be our last threat. We need to use the American Rescue Plan to fund and scale testing, genomic surveillance and outbreak analytics to get us through this crisis and ready for the next.
Congratulations to BE GREATEST Award winner, Mary Wilson! Mary is recognized by her team for going above & beyond setting up biosafety processes in our new headquarters.
Are you driven to
#BEGREAT
& bring out the best in your team?
#WomenInSTEM
Join us:
Our entire team shares our CEO
@rahulkdhanda
's commitment to antiracism.
On Building Biotech, he shared why we strive to recruit BIPOC talent, invest in education for
#WomenInSTEM
, and dismantle structural racism by building better healthcare.
Read his letter to our staff.
Thank you
@nabsicle
and
@Jack_O_Meara
for the incredible fun I had on your Building
#Biotech
@joinClubhouse
event.
Thank you to all the participants. As promised, below is the letter I sent to my company after the horrible events surrounding George Floyd's death.
Sherlock Biosciences stands in solidarity with the Asian-American Pacific Islanders (AAPI) who live in our communities and work in our biotech industry. We pledge to stand up against anti-Asian hate & discrimination to ensure a safe and inclusive community.
#StopAAPIHate
We celebrate the
#LGBTQ
+ community during
#PrideMonth
& voice our commitment to advancing
#DEI
in
#biotech
by advocating for LGBTQ+ visibility and representation.
Read more from
@IAmBiotech
2021 Diversity Report:
This
#AAPIHeritageMonth
, we celebrate the diverse cultures in the
#AAPI
community. We honor the contributions to
#STEM
made by Asian American scientists like virologist Dr. Flossie Wong-Staal who's research was critical to combatting
#HIV
.
#DEI
Read more:
Sherlock Biosciences celebrating the Groundbreaking of our new Headquarters located in Arsenal on the Charles. Thank you to our new neighbor
@_BranchLine
for hosting us!
Yesterday
@Sherlock_bio
broke ground on our new HQ!
Thank you to our amazing team of partners who are building a space that reflects our culture, values, and commitment to scientific innovation: our landlord Alexandria Real Estate Equities,
@WiseBuilds
,
@CBRE
& OTJ Architects.
Today we announced the discovery of novel CRISPR-Cas enzymes that enhance, simple multiplex
#diagnostic
solutions, furthering the utility of our
#CRISPR
toolkit in molecular diagnostics and point-of-care settings.
“No one questioned whether we could do it. Everyone said this is how we’re going to do it.” As true today as it was 1 year ago when we made history with the first FDA authorized use of
#CRISPR
technology.
Our proprietary
#CRISPR
&
#SynBio
engineering biology tools for DNA & RNA detection will bring next-generation diagnostics to the point-of-need.
We will transform diagnostics &
#GlobalHealth
by helping people access health information wherever they are.
At Sherlock, we wanted to create a space where we can all dream — a place for our talented individuals, amazing teams, and caring community to thrive and move forward in our mission to change global public health.
Welcome, everyone, to our new headquarters.
#HQ
#biotech
Congratulations to our Co-founder David Walt, a 2021 winner of the Kabiller Prize in Nanoscience and Nanomedicine!
@IINanoNU
recognizes Walt as a pioneer for his work developing ultrasensitive single-molecule array detection technology and its impact on medicine and biology.
Thank you
@BioCentury
for including us in your top 10 stories of 2020. Just 2 months after "CRISPR-based diagnostics are poised to make an early debut..." published, we made history with the first FDA-authorized use of
#CRISPR
technology with our
#diagnostic
to fight
#COVID19
.
Sherlock Bioscience's team received a $7.5 million grant advance from
@open_phil
to develop at-home
#COVID19
tests. We are thrilled to invest in our
#Sherlock
Innovation Lab by hiring local experts to bring
#INSPECTR
to the public.
In partnership with
@AlbotTechnology
, our
#CRISPR
technology will generate 1 million tests per month in India as they confront the challenges posed by new
#COVID19
variants.
At Sherlock, our team is committed to helping people access health information wherever they are.
We aim to transform health outcomes worldwide with our
#CRISPR
,
#SynBio
and
#AI
tools for DNA & RNA detection by bringing next-generation
#diagnostics
to the point of need.