The MLY(narczyk) lab👩🔬is opening at
@Yale
this July! Excited🎉to explore immuno-metabolism in germinal center-derived B cell malignancies🦠🦀. Recruiting trainees at all levels, please RT/DM/email if interested or for recs. Our latest: 1/3
✔️nicest lab farewell ever
✔️smooth home move
✔️clean up old lab space
✔️prep for transition as much as possible
bye
@WeillCornell
, I will come visit!
hi
@Yale
, ready for new adventures!
thanks to ALL, old and new, who helped so much for this to happen ☺️
#newPI
First postdoc position ad out on the
#AAI2024
jobs board! we are starting July 1st and are also recruiting technicians & postgrads and will welcome grad students to join! Check the ad for details on the research and the lab!
#Immunology
Thank you
@victora_lab
with Drs. Juhee Pae and Jon Ersching for helping us decipher the GC dynamics perturbation in this story! We did some quite crazy experiments💥 and it was such a pleasure to work with you, can't wait for the next ones to come!
Great work from
@coraline_mly
and
@LabMelnick
in
@ScienceMagazine
, on how mutations in BTG1, an important DLBCL oncogene, affect germinal center dynamics by speeding up the positive selection process (in collaboration with Dr. Juhee Pae from our lab)
was amazing to be included in this
#newPI
gathering! great to hear that everyone meets unexpected challenges but also it is so much joy to run your own lab :)
Come learn and discuss about *mechanisms* 🕵️🔎 of therapy resistance in blood cancers! 🗓️tomorrow Friday 12/8, 2-5pm,📍room 7 upper level
#ASH23
scientific workshop
My first
@ImmunologyAAI
meeting!
Excited to share new research on Competition 👯♂️ in the GC and to have
#Immunology
for breakfast lunch dinner and in between!
- presentation 5/4 at 5:30
- poster 5/5
please say hi, would love to chat!
#AAI2024
Terrific poster presentation by
@LScourzic
last night! Stay tuned for more on GC B cell *remarkable* plasticity 😁 and congrats on the
#ASH2023
abstract achievement award!!
@lymphoma
@WeillCornell
Excited to head to sunny San Diego for
#ASH23
! Looking forward to catching up with past, current & future colleagues. Thank you
@ASH_hematology
for the
#AbstractAchievementAward
. Stop by poster session on Sunday 10th 6-8pm to chat about GC B cells plasticity & B cell lymphoma👇🏻
Fantastic lymphoma biology session chaired by
@GreenLymphoLab
and
@coraline_mly
— these projects bringing complex multi-omics approaches into *models* of lymphoma that can be analyzed longitudinal and perturbed are so exciting! Moving from correlations ➡️ causation!
Ever thought about how HSCs survive under proteome toxicity in VEXAS or generally Curious about VEXAS syndrome??
Come join us on Monday
#ASH2023
@ 3.15 pm in SDCC room no. 24.
We have great techniques developed and cool biology to discuss on VEXAS syndrome…
To really test this idea, we did the thing – the memory B cell recall experiment. The crazy effort was worthwhile – memory B cells lacking ARID1A were recalled to the germinal center at a significantly higher rate. Thank you
@coraline_mly
. 12/n
🔥 Meet our speakers at the Postdoc Research Day 2022!
Dr. Coraline Mlynarczyk
@coraline_mly
, Research Associate in Medicine in the
@LabMelnik
at
@WeillCornell
, will tell us more about how changes in B cells competitive fitness contributes to their transformation into lymphoma
Recharged with tons of ideas 🤩 after
#KSBTCELLS24
@KeystoneSymp
in Whistler. Thanks to everyone for all the feedback and advices, and for being so approachable. Looking forward to next year’s!
so happy for the glimpse at all the science and medicine happening and for catching up with so many fellow researchers! thanks
#ASH22
and
#NewOrleans
🐊
Thank you so much
@ASH_hematology
! Very proud and honored to receive such a prestigious award. Thanks to my mentor
@LabMelnick
and everyone in the lab for the support and team work! 😄And now onto more
#hematology
#research
🩸🔬
Today, we proudly announce the 36 recipients of our 2021 ASH Scholar Awards, one of our most prestigious research award programs for fellows & junior faculty dedicating a
#career
to
#hematology
research! 🎉🩸
#ASHAwards
Read about our awardees today:
Very excited to share our new paper on how mutations in SWI/SNF chromatin remodeling complexes alter chromatin dynamics and immune cell-fate to drive lymphoma, online now in
@Cancer_Cell
.
More details in the thread below.👇 🧵 1/n
Strongly recommend participating in the next symposia of
@Tri_I_RNA
for anyone into
#RNA
! lots of different study angles, refreshing science and super stimulating 🧠💡
We had a great symposium with fantastic speakers, awesome audience, fun trivia, and food and drinks afterwards!! We thank our sponsors
@ACDbio
@AzentaSciences
@TwistBioscience
for making it possible! 👏👏
Come join us for the latest on Lymphoma • Jun 19-22 • Philadelphia • Abstracts submission until Apr 1st.
AACR International Meeting on Advances in Malignant Lymphoma
#AACRlymph24
chaired by Michael Green
@GreenLymphoLab
.
Program:
The AACR on Malignant Lymphoma (& GC biology, immune synapse, CAR-T and many other topics💫) has extending the deadline for abstract submission >Friday April 19.
They have $500-$1,000 abstract awards to support early-career members!
more details here:
So happy and grateful for the opportunity to join
@YaleCancer
faculty, for the enthusiasm and support of
@MuschenLab
,
@DrEricWiner
and so many others. Cannot wait to get started! 2/3
Inspiring science happening in the
@MuschenLab
, developing new models of lymphoid malignancies and asking exciting, fundamental questions. Thank you for sharing! Looking forward to see where this goes.
Coraline Mlynarczyk
@coraline_mly
from
@LabMelnick
visiting us today and shared her concept of 'supercompetitor' germinal center B-cells and their role in lymphomagenesis. Insightful brainstorming session with Coraline (middle) and members from our lab.👇
submit your exciting research for the AACR on Lymphoma! deadline is approaching, April 1st 🗓️:
🏆 awards for highly rated abstracts for early career investigators
Submit an abstract by April 1 for the Fourth AACR International Meeting on Advances in Malignant Lymphoma (June 19-22, Philadelphia), chaired by Michael R. Green and organized in association with
@BCD_AACR
. Learn more:
#AACRlymph24
@GreenLymphoLab
Next up in our
#2020highlights
: Dr.
@coraline_mly
received THREE awards 🤩 The ASH Fellow to Faculty Scholar Award in basic/translational research, The ASH Restart Award for early career investigators & The LRF Scholar Award for the 2021 LSRMP. Many congratulations to Coraline🥳
How do BAF (SWI/SNF) mutations drive lymphoma? Back-to-back papers from our group
@MDAndersonNews
and
@LabMelnick
lab on SMARCA4 and ARID1A mutations online in
@Cancer_Cell
today. A brief summary...
Thanks
@LVentuLab
for the invite to visit you at
@BCCancer
. Great friend and ex postdoc-mate :) was great to catch up! Everyone: if you are looking for a lab, strongly recommend reaching out to Leandro, fantastic mentor&scientist and perfect place to do lymphoma research🧑🔬
Some of the things Ari
@LabMelnick
does for his mentees:
“He taught me how to think critically, read graphs, and even how to navigate politics and stay humble. He taught me how to keep going after failures, and to aim for more when you’re doing well.” 👇
March 2020: we were just back from
#Keystone
#Banff
👩🔬🌄. Full of ideas but with no idea of what was coming. So much has happened and *not* happened over the last year, it feels like an eternity ago, but things are looking ✨brighter✨now
Starting our
#2020highlights
all the way back in March (which feels like a lifetime ago). Pre-pandemic lab visit to beautiful Banff, Alberta for the B Cell Renaissance: Epigenetics, Regulation and Immunotherapy
#keystonesymposia
meeting 🧬 ❄️
#throwback
Announcing again a unique workshop on Lineage Plasticity & Cell-of-Origin of Hematologic Malignancies this Friday October 14, 2022. Hosted by
@CHM_MSKCC
&
@MSKPathology
@MSKCancer
Center. Registration and updated final agenda below:
COMING UP: LRF grantee
@coraline_mly
of
@WeillCornell
to present findings from "Mutation Promotes Aggressive Lymphoma Development By Lowering the Threshold to MYC Activation and Generating 'Super-Competitor' B Cells" at
#ASH21
Read more:
So happy for my friend
@MartinRivasPhD
!🎉👏. Can’t wait for the great science to come 🧬 if you are looking to do exciting 3D genome research, don’t hesitate, Martín is the best and most dedicated person I know when it comes to training mentees 🙌
I am thrilled to announce that I have accepted a position as an Assistant Professor at the Department of Biochemistry and Molecular Biology at the
@univmiami
and the Sylvester Comprehensive Cancer Center
@SylvesterCancer
🎉🥳
Smart bone marrow chimera model to help decipher the complexity of autoimmune B cell populations generated from a endogenous BCR repertoire -it is not only about one type of antibody secreting cells!
👉WCM trainees & mentors, you can stop by tomorrow to hear about your postdocs’ research and show you care! Selected oral presentations from
@LScourzic
,
@GoniaGuy4
, …🦸 Last year’s was great!
@WeillCornell
@WCMPostdocs
Today, we're announcing the 19 deserving recipients of our new ASH Research Restart Award. We created this award to support researchers amid the uncertainty of the
#COVID19
pandemic. Congrats to all! 🎉
Read about the awardees today:
Cancer cells can enter a state of "active hibernation" that protects them from being destroyed by chemotherapy and explains why cancers so often recur after treatment, finds new research by Dr. Ari Melnick (
@LabMelnick
) of
@WCM_MeyerCancer
.
I am very excited to share the final story of my PhD, online now as a pre-print in
@biorxivpreprint
, where we dissect the opposing effects of antibody-feedback and memory T cell help on recall germinal centers (GCs). 1/n
#Pr
ésidentielle2022 🗳 | L’élection bat son plein au
@LyceeFrancaisNY
, où de nombreux lycéens se sont portés volontaires pour accueillir les électeurs !
I have met wonderful people & scientists throughout the interview and recruitment process and I hope I will keep interacting with them for years to come. 3/3
Starting our
#2020highlights
all the way back in March (which feels like a lifetime ago). Pre-pandemic lab visit to beautiful Banff, Alberta for the B Cell Renaissance: Epigenetics, Regulation and Immunotherapy
#keystonesymposia
meeting 🧬 ❄️
#throwback
#Research
by Drs. Coraline Mlynarczyk & Ari Melnick
@WeillCornell
found that BTG1 mutations can lead to more aggressive B-cell
#lymphomas
. Exploiting this genetic vulnerability could ultimately create new therapies for patients:
#ASH21
Last but not least, like Sisyphus condemned to push a rock up, for it only to roll back down, mutant BTG1 pushes a heavy GC (pic🌟 by
@LukaMesin
) for it only to recycle back to the DZ and clonally expand, forever. Lymphoma B cells EM in the back. Art by talented✨
@afterpartylost
First postdoc position ad out on the
#AAI2024
jobs board! we are starting July 1st and are also recruiting technicians & postgrads and will welcome grad students to join! Check the ad for details on the research and the lab!
#Immunology
.
@SciImmunology
is excited to announce
@hmisles
as a new Associate Editor. Dr. Isles did her PhD on neutrophil biology at
@sheffielduni
and joins
@AAAS
after a postdoc studying B cell lymphoma at
@WeillCornell
. Hannah, welcome to the immunology branch of the Force for Science!
@jdpereira
i use apple desktop mail. have all mailboxes in there, synchronized across devices. and now i create rules for less urgent emails (eg listservs) to go to a separate folder where i do not get notified and check them at night, so i don’t get constantly distracted :)
Mitochondrial function is essential for humoral immunity by controlling flux of the TCA cycle, phosphatidic acid and mTOR activity in ...
#biorxiv_immuno
📣 Calling BSc and MSc students enthusiastic about RNA Cancer biology: new PhD position funded by Cancer Research UK in my lab. This comes with amazing training and development opportunities by CRUK! . Only for UK or settlement students!
Read the profiles of the 2021 Career Development Award (CDA) and Postdoctoral Fellowship Grantees, in pursuit of
#lymphoma
and chronic lymphocytic leukemia (CLL) specific research projects. Click below to learn more:
with Thein Arulraj, Arnab Bandyopadhyay and Michael Meyer-Hermann for 📈deep mathematical modeling of germinal centers,
with Ken Hoehn for unraveling B cell clonal trajectories 🌴 2/
CCHMC Division of Immunobiology is hiring faculty (at all ranks).
Applicants should send a CV, 2-page research plan, and contact information for three
references to Immunobiology
@cchmc
.org by March 1st, 2024.
Watch “Fight for Sight 2022” on
#Vimeo
featuring pioneering science and a preview from the twitterless Nefeli Slavi styding retina
@drcarolmason
drcarolmason lab
@ZuckermanBrain
. More exciting retina research soon…
We are pleased to announce the recipients of the 2021 LRF early career
#lymphoma
research grants. Among the LRF grantee class are researchers within LRF's Health Equity Initiative, and the expanded Lymphoma Scientific Research Mentoring Program (LSRMP).