Maya Schumer, PhD
@SchumerMaya
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Following
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Postdoc Fellow⚡️ @McLeanHospital / @HarvardMed | Neuro PhD💥 @PhillipsLabPitt / @PittPsychiatry | #BipolarDisorder ✖️ #Neuroimaging | #LivedExperience #DisabledInSTEM
Boston/Belmont, MA (USA)
Joined August 2022
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Pinned Tweet
I’ve been holding this in for 10 years: I first joined Twitter to keep up with the science of my peers, but I ended up finding an entire community that I was missing in my daily life: people living w/
#BipolarDisorder
…a community to which I also belong. 1/6
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As my wise peer & fierce mental health advocate
@DrDevikaB
said when she "came out"w/BD: “Stigma festers in the dark and scatters in the light.” My hands shake writing this, but I also know that my words may make it easier, & safer, for others to come out of the darkness too. 4/6
1
1
59
Dr. Nev Jones(
@viscidula
); Brandon Staglin(
@BStaglin
); Dr. Devika Bhushan(
@DrDevikaB
); Maj.Gen. Gregg Martin(
@GenGreggMartin
); Dr. Iain Campbell(
@IainCampbellPhD
); Dr. Andrea Vassilev; and my very first hero and inspiration: Dr. Kay Redfield Jamison. 6/6(end)
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Are there differential 🧠 network patterns that uniquely characterize risk for
#mania
vs
#depression
? Our new work, our now in
@JAMAPsych
, found
#replicated
❗️neural responses linked with syndromal and sub-threshold mania/hypomania & depression…🧵
Cross-sectional study identified neural markers distinguishing, and common to, risk for mania/hypomania and depression replicated in three independent young adult samples, with implications for bipolar disorder risk detection.
@SchumerMaya
@MaryPhillips23
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To also quote Anya Burčak(
@CalculatingMind
): “Disclosure should not be an act of bravery.” I envision a future where we can openly share our lived experiences without risk, consequence or prejudice. I'm grateful to my heroes &role models who've fearlessly paved the way for me:5/6
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#SOBP2024
was a very special & exciting one for me, as it was the first time that there was a panel/event on
#livedexperience
,
#stigma
&
#disclosure
@SOBP
. As a researcher w/ lived experience, this was something I had always wanted to see. Many thanks to our panelists & JEDI! 💙
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...studying bipolar disorder, ironically), I also believe in the power of community, and so I hope that by finally breaking my silence about my own
#livedexperience
w/ bipolar disorder, I can add to the collective effort towards ending this vicious stigma altogether. 3/6
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Are there reliable, reproducible neural differences in
#BipolarDisorder
, given heterogeneity? In our new work, out now in
@molpsychiatry
, we synthesize several decades of functional
#neuroimaging
in BD via a large-scale
#metaanalysis
of 205 studies
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It happened!!💥🤓🧠Defense done, PhD in sight⚡️Grateful to my support team et. al❤️especially my mentor,
@MaryPhillips23
@PhillipsLabPitt
& my 🎨mom. Excited to keep moving forward in this field while breaking the
#stigma
around
#BipolarDisorder
!
9
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It didn’t take long for me to begin connecting w/ others, thereby making me feel less alone (& less ashamed- rooted in my own internalized/self-stigma). While I’ve always believed in using science to help break the stigma around psychiatric disabilities (I’m a neuroscientist…2/6
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SO excited to co-moderate the‼️FIRST-ever‼️
@SOBP
🔥Fireside Chat🔥focused on
#InvisibleDisabilities
,
#Stigma
&
#LivedExperience
feat. Drs. Nev Jones
@viscidula
, Linda Williams
@EndInvisibility
& Andrea Vassilev, presented by SOBP's JEDI committee. Friday 5/10 @ 12:30 PM!
#SOBP2024
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‼️Excellent & important
@molpsychiatry
@DenfieldGeorge
piece drawing attention back to
#subjectivity
&
#livedexperience
arguing the many ways in which they greatly inform
#psychiatry
&
#neuroscience
- a must-read‼️
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Increasing visibility, solidarity & strengthening community among
#livedexperience
/
#disabled
research scientists & service users has the capacity to transform psychiatric neuroscience. We need meaningful
#co
-production & active inclusion of these groups in our field NOW.
@IainCampbellPhD
I feel like I have a front row seat to watching something historic happening in medicine. Thank you
@IainCampbellPhD
for all your work!
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In (belated) honor of
#WorldBipolarDay
, I share this painting by my mother/artist Sherri Wolfgang, on the prevalence of
#BipolarDisorder
in our society, especially among creatives. Now on tour with the Ryan Licht Sang Bipolar Foundation ()
#BreakStigma
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Pumped to be giving my first talk
@SOBP
next Thursday, presenting some cool data from
@PhillipsLabPitt
! Come by if you’re interested in hearing about ⚡️replicated⚡️neural network markers associated w/ mania/hypomania risk vs depression risk in young adults
#SOBP2023
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Back in 2011, when I was 17, I saw
@HelenMaybergMD
give a Grand Rounds talk
@Yale
on this research, where I learned the term “biomarker,” and that was the *moment* I knew I wanted to become a clinical neuroscientist. Congrats
@HelenMaybergMD
and team, thank you for inspiring me!
🧵
#5
The moment is here: our latest study is out in
@Nature
!
To catch you up: 20 years of investigating DBS for treatment-resistant
#depression
& we found a 🎯 (SCC), refined precision, gauged long-term efficacy & spotted early signs of recovery.
Now, we have exciting news...
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🎉 Congratulations to our newest cohort of
#NeuroScholars
!
Welcome to a growing community of over 1,300 underrepresented neuroscience researchers of all career stages.
#NSPeep
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“Jamison’s difficult decision to disclose that she has
#bipolar1disorder
—although she continues to prefer the term manic-depression for its descriptive accuracy—made her one of the early heroes of the bipolar community.”Eradicate
#stigma
so disclosure is no longer difficult/risky
Kay Redfield Jamison uses her own experiences with mania, psychosis, and suicidal depression to enrich research into the historical & cultural roots of psychotherapy in her new book Fires in the Dark: Healing the Mind, the Oldest Branch of Medicine.
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Great time reconnecting with
#BipolarDisorder
#stigma
-buster💥
@GenGreggMartin
in Boston celebrating the preview of
#BrainStorm
, an important upcoming documentary shedding light on the bipolar spectrum (led by
@SaraSchley
/
@BonnieWaltch
). Learn more: ❗️
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Had a great time presenting some of the latest work from
@PhillipsLabPitt
at
@ISBD4
and learning from others in the field doing exciting work on
#BipolarDisorder
#ISBD2023
@SchumerMaya
presented her amazing study on (replicated!!!) neuroimaging predictors of mood symptoms in bipolar disorder
@ISBD4
#ISBD2023
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New
@JAMA_current
piece by
@MelissaSuran
on
#BipolarDisorder
importantly quotes from persons with
#livedexperience
such as
@DrDevikaB
. We need WAY more
#livedexperience
inclusion/participation in psychiatric biomedical research‼️ They inform one another.
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Excited to be a panelist for the upcoming
#WorldBipolarDay
“Ask Me Anything" event starting on 3/19/2024! More info:
The BIGGEST
#BIPOLAR
Q&A event on the internet is happening on March 19th for
#WorldBipolarDay
! 🌍
Bipolar disorder experts from around the world will answer your questions on Reddit for over 48hrs! Learn about
@CREST_BD
's 6th annual "Ask Me Anything":
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In a
#mixedepisode
, it can feel like the brain is on fire. As the most high-risk mood state in
#BipolarDisorder
for suicidality, it needs more attention from the
#neuroimaging
field.
What symptoms do you experience while in the throes of a mixed mood episode?
Let's educate the masses.
#bipolardisorder
#bipolarclub
#bipolar
#MentalHealthAwareness
#MentalHealthMatters
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Interested in neural network functional connectivity patterns🧠associated with vulnerability to
#BipolarDisorder
?📈I'll be presenting these findings from
@PhillipsLabPitt
next Friday morning at
@ISBD4
's oral session on biomarkers, big data, machine learning, & genetics!
#ISBD2023
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Fascinating talk yesterday at
@ISBD4
by
@McClungColleen
on circadian rhythm alterations underlying
#mania
in
#BipolarDisorder
💤⏰🧬🐭💤 chaired by
@MaryPhillips23
#ISBD2023
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Let's reinvent how we assess neuropsychiatric disorder symptoms. Not all can be quantified/Likert-style rated. To better capture complex symptoms/sensations (e.g. brain feels like it's on fire), we need more creative measurement/reporting methods. We miss what we don't ask about.
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Many soundbites from this convo btwn
@awaisaftab
&
@dost_ongur
! My favorite re:the need for more imagination in our field:“the constant parade of fashions without genuine creativity makes me think that our field needs, like Proust, not to seek new landscapes but to have new eyes”
Building a Shared Scientific Understanding of Psychopathology: Q&A with Dost Öngür (
@dost_ongur
)
The editor of JAMA Psychiatry reflects on the state of psychiatric science
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A reminder that
#mania
is not just feeling 'euphoric' & symptoms aren't limited to 'talking fast' or 'disorganized thinking.' Mania can become a dangerous trick your brain plays on itself, resulting in a loss of control that can be
#disabling
.
#BipolarDisorder
How can something which can feel so good at the time simultaneously be a potentially harmful serious episode of illness?
Just one of the puzzles of bipolar - articulated very interestingly in this short article:
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#LivedExperience
inclusion is critical for moving all
#MentalHealthResearch
/-related fields forward & making tangible, positive impacts on those living with
#SMI
/
#mentalillness
&
#PsychiatricDisabilities
.
#BiologicalPsychiatry
/
#PsychiatricNeuroscience
fields, please take note!!
Nothing is more powerful than the voices of those of us who have lived through mental health challenges. Let's prioritize our inclusion in policy and program development for better
#mentalhealthforall
.
#LivedExperience
#InclusivePolicies
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@janellison
@Radiantbeasting
Jan! Thank you,
@BaszuckiMatt
and your family for changing the world of bipolar research and bringing more attention and gravity to how vicious this illness can be —and how important it is that we find answers.
@BD2Discoveries
is already doing so much for us, thank you again🙏🏻❤️
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@Claudia_I_Lugo
@aliceaizza
DM me I had similar experience when I got my NSF GRFP (and I have program suggestions)
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“Mental” health IS physical & we must keep working towards universal establishment of healthcare equity for ALL disorders/diseases/disabilities/chronic illnesses for ALL people and BREAK the stigma around “mental”/brain health.
I don't know many people who have spent more than $300K out-of-pocket on health care for "physical" disorders.
I know many people who have spent that much and more for mental health care.
#Injustice
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Fantastic fellowship opportunity from
@AWISNational
. Grateful to have received the doctoral dissertation scholarship last round, happy to answer any questions.
@Women_inNeuro
@500womensci
@QueerInNeuro
@LatinxInPsych
@LatinxInNeuro
@DisabledStem
@BlackInNeuro
@DisabledInPsych
🚨 Please share! 🚨 Applications are open for AWIS
#scholarships
, and we have even more to give this year! We have up to 13 awards for
#WomenInScience
who are pre-doctoral students, women re-entering the workforce, and undergraduates. Apply by February 28!
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Every day is
#WorldBipolarDay
for those living with the illness. If we’re going to improve quality of life, treatments, and outcome for those w/ bipolar disorder, we need to listen to, elevate, + include the voices of those w/
#livedexperience
in our research and anti-stigma work
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‼️Looking for a
#postdoc
in cutting-edge
#psychiatric
#neuroscience
? 🧠📈Check out these
@PhillipsLabPitt
postdoc opportunities
@PittPsychiatry
@PittHealthSci
‼️
@OHBM_Trainees
@WINRePo1
@AWISNational
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"We need to face the hypocritical ableism that exists within our field." / "Disclosure should not have to be an act of bravery." Great article with many important points made by
@CalculatingMind
.
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"There is a critical need for researchers and clinicians to advance the prevention and treatment of BD especially given recent findings that there is a pronounced lack of funding for clinical research and treatment development for BD." ‼️ Important article by
@EMC_ISBD4
@ISBD4
‼️
The EMCC conducted a global needs survey on barriers to and facilitators of success for early and mid-career professionals focused on bipolar disorder. Read about their study and results now published in Bipolar Disorders!
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@awaisaftab
“Unfortunately, “scientific” is often used as a tool to dismiss lived experience as anecdote, as an excuse not to take a phenomenon seriously until RCTs & meta-analyses have been carried out. A liberatory psychopharmacology should be…
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PSA re: the Mood Spectrum Self-Report(MOODS-SR)- can capture not only sub/threshold-level manifestations of manic/hypomanic & depressive symptoms over someone’s lifetime, but also behaviors/traits, mood dysregulation & mixed features associated w/ the phenomenology of mania...
Using the MOODS-SR (), a sensitive, comprehensive spectrum measure of mania and depression risk, and an approach emotion-related
#fMRI
task context, we identified 2 distinct neural network response patterns associated with mania vs depression risk…
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‼️We need more work like this, reevaluating these “gold standard” symptom measures…and we also need to take a second look at how we’re measuring
#mania
/
#hypomania
, starting with the YMRS‼️We miss what we don’t ask about.
8/ The HRSD was developed in 1960. Today, it remains the most commonly used depression scale in clinicals trials (≥90% of studies in recent meta-analyses).
We learned a lot about depression in the last 60 years. But we still measure depression with the knowledge of 1960.
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@ChrisPalmerMD
You’ve lit the path!! 🙏🏻❤️⚡️Thank you for uplifting my story and for all that you do for our community -and loved running into you @ McLean!
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Self-stigma and bipolar disorder: A systematic review and best-evidence synthesis
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Grateful to today’s visionaries and stigma-breakers such as
@viscidula
@BStaglin
@DrDevikaB
@IainCampbellPhD
🙏🏻🧠
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Thank you
@BBRFoundation
for your great coverage of our recent
@JAMAPsych
paper w/
@MaryPhillips23
@PhillipsLabPitt
@PittPsychiatry
! “Neural Activation Patterns That May Help Distinguish Elevated Mania/Hypomania Risk From Depression Risk in Young People”
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@FriesGabriel
@ISBD4
@EMC_ISBD4
@DrHosang
@RebekahHuberPhD
@DrSarahSperry
@jaircsoares
@fagomes1981
So excited for this! Thank you
@EMC_ISBD4
for putting this together 🙏🏻
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Mixed/dysphoric manic episodes are often harder to treat than "classical" i.e. euphoric mania, last longer, often get misdiagnosed as unipolar depression, and elevate risk for suicide. More education & research are needed. Thank you
@IntlBipolar
for drawing attention to this!
Bipolar disorder is not limited to a vertical experience of depression or mania; both can occur simultaneously at different levels. We understand what you are going through. 💚
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@DrSarahSperry
Also thank you for welcoming me into the close-knit
@EMC_ISBD4
community!!
@FriesGabriel
@fagomes1981
@erin_michalak
@TamsynVR
@RebekahHuberPhD
and more…I’m so grateful to be part of the team. ❤️🧠
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Being
#bipolar
is like being stuck on a roller coaster where one moment you're having fun and the next you want to vomit, but either way you aren't in control of the ride. People assume that bipolar is just
#moodswings
, but it's so much deeper, and darker than that.
#ihateit
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@Radiantbeasting
@SOBP
So amazing to finally meet you in person (along with
@LWSchizophrenia
and
@janellison
!!) at the tail end of the
@Metabolic_Mind
/Baszucki Group pre-meeting - I’m also about to email you to find a time to zoom-sorry for the delay 🙂
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@LowCarbEyeDoc
@GenGreggMartin
@SaraSchley
@BonnieWaltch
I highly recommend it!
@GenGreggMartin
is a force- not only through his enthusiastic and unwavering mental health advocacy and fight to end stigma, but also in his writing.
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@NatureCareers
@NIH
@BonnieSwenorPhD
@cjmoreland
@VirginiaGewin
Great to see this much-needed call-to-action for the inclusion and elevation (e.g., to leadership positions) of researchers w/ disabilities whose lived experience is sure to make an informative impact on research while dismantling systemic stigma/abelism.
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v important and valuable paper by
@TheTealTigerUK
and team: “Identifying the priorities for supervision by lived experience researchers: A Q sort study” ‼️‼️
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@UmaRChatterjee
@DisabledStem
@NatRevMater
This is amazing, Alyssa. Ditto to what Uma said. Keep going- you have all of us rallying behind you. 🙏🏻⚡️⚡️⚡️
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Researchers identified several patterns in
#brain
activity in young adults that appear to distinguish elevated risk of
#mania
/hypomania from elevated risk of
#depression
.
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@viscidula
@SusanRogersMH
Congratulations Nev!! I am honored and grateful to know you and look up to you in so many ways! Thank you for all you do for destigmatizing and advocating for those with psychiatric disabilities. 🧠❤️✨
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@Wal_yas
@TMP_HMS
@TheLancet
So many great and critical points, thank you
@Wal_yas
for laying it all out in this thread. This is a timely and extremely important commission that I hope becomes widely disseminated, especially the notable inclusion of PWLE in this discourse and their valuable insight.
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This was a great collaborative effort between
@PittPsychiatry
prof Henry Chase,
@PhillipsLabPitt
postdoc Renata Rozovsky, Simon Eickhoff
@INM7_ISN
and
@MaryPhillips23
.
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“equitable psychopathology understands pathology as the relationship btwn endogenous difference & ill-health…Understanding psychopathology in this way can reveal the judgments/norms incorporated in the idea of dysfunction & invites a collective responsibility for mental health.”
An interesting conversation between David Mordecai and
@awaisaftab
about the personal experience of bipolarity and psychopharmacology. Worth reading
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Public stigma perpetuates internalized stigma/self-stigmatizing.
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@DrSarahSperry
Also so excited for the many future collaboration opportunities that await us and
@dost_ongur
!
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scientific in the broadest & most virtuous sense of the word. It should be informed by all sources of evidence—experiences of individuals who use substances, the experiences of clinicians, the observations of families and caregivers, clinical trials, observational studies,…
0
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@EMC_ISBD4
@ISBD4
"The retention and success of EMCs [early and mid-career researchers] are essential in securing the future of the field. The benefits of this will be felt not only by the researchers and clinicians themselves but also by those who live with BD."
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@jimprisciandaro
@DrSarahSperry
Agreed on all of the above. Thanks for bringing attention to this issue that I also noticed when reviewing articles for the meta, and excited to see the efforts that come out of
@BD2Discoveries
to address this gap.
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Thank you to my committee,
@McClungColleen
@FabFerrare
@forbes_erika
@scottlangeneck1
& Tim Verstynen of
@cmupsych
!
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Using the MOODS-SR (), a sensitive, comprehensive spectrum measure of mania and depression risk, and an approach emotion-related
#fMRI
task context, we identified 2 distinct neural network response patterns associated with mania vs depression risk…
1
1
1
@UmaRChatterjee
@NAMIWisconsin
@IOCDF
@ocdaction
@TheOCDStories
@treatmyocd
@biohaven
@UWMadison
@uw_ntp
@NAMICommunicate
@AChatWithUma
@ipnpsychedelics
YES UMA‼️‼️‼️You’re amazing🙌🏻❤️
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@DrSarahSperry
@CDelawalla
@jimprisciandaro
@aidangcw
@HiTOP_system
“thirded”! We found this in my dissertation work in young adults with subsyndromal-subthreshold mania/hypomania -strong correlations between neg and pos urgency. Three-factor impulsivity index collapses negative and positive urgency together along with “feelings trigger action”
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@FriesGabriel
@jaircsoares
@uthpsychiatry
@McGovernMed
Thanks again for a fantastic talk, many exciting future directions and treatment applications for epigenetics in BD! 👏
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Also incorporating
#livedexperience
is key for improving and *creating new* measures for
#mania
,
#psychosis
, etc…
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❗️🧠❗️All files used for analyses, associated references for all included papers, and all meta-analytic maps and contrasts have been made available to download and visualize from the Archive of Neuroimaging Meta-Analyses (ANIMA) database:
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@FriesGabriel
@molpsychiatry
Thank you Gabriel! Would love to hear your thoughts on the findings and conclusions sometime soon.
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