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ChemBark

@ChemBark

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News, Analysis, and Commentary for the World of Chemistry and Chemical Research. The site is maintained by Paul Bracher ( @ChemBarkPaul ).

St. Louis, USA
Joined August 2010
Don't wanna be here? Send us removal request.
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@ChemBark
ChemBark
2 years
Did you really need to buy that kilogram of RNA 40 years ago?
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@ChemBark
ChemBark
3 years
Organic chemists: how would you name this alkene?
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@ChemBark
ChemBark
2 years
The future of poster presentations is now. I’m at a conference. There’s a room full of poster-sized touch monitors. You can call up your poster and interact with items and zoom into boxes. Visitors can also quietly browse all posters alone. It’s all electronic. No more printing.
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@ChemBark
ChemBark
2 years
Orgo friends! As the academic year begins, this is just a friendly reminder that every major organic text gets the nomenclature of alkenes and alkynes wrong. IUPAC updated the rules in 2013, but our texts have not followed. Here's an easy way to fix your course materials...
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@ChemBark
ChemBark
3 years
A short thread on disability in chemistry and some food for thought. Again, I hate to be the one writing this. I'd much rather someone else did it so I could just retweet, but here we are... (1/12)
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@ChemBark
ChemBark
3 years
It's fine to wonder how legendary PIs thrived as major bullies in chemistry decades ago... ...but it's better to stop worshipping bully PIs in chemistry today. Stop inviting them to give talks and stop giving them awards. Speak up. Don't humor them. Warn junior scientists...
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@ChemBark
ChemBark
3 years
My wife and I met online. She was attracted to me because I was a man of Science. She left me when I became a man of Tetrahedron Letters.
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@ChemBark
ChemBark
4 years
If you think the toxic culture of organic chemistry needs to improve, consider giving fewer honors and invitations to PIs who built their careers on the broken backs of their students and more to PIs who offer their students’ helping hands.
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@ChemBark
ChemBark
3 years
The new version of ChemDraw is wild...
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@ChemBark
ChemBark
4 years
To all those suddenly reticent PIs who, in June, were blasting Hudlický and the lack of diversity in organic chemistry, don’t you think that the iniquitous demand of long work hours could be part of the problem?
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@ChemBark
ChemBark
1 year
Never underestimate the value of a well-rounded, liberal arts education.
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@ChemBark
ChemBark
4 years
Ok, I’ll say it… This letter is polluted by an undercurrent of hypocrisy in that some of these PIs are quite familiar to students as purveyors and beneficiaries of the toxic culture made manifest in the Hudlický essay.
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@ChemBark
ChemBark
4 years
I am surprised that this tweet has received over 900 likes and over 350 retweets without anyone having challenged its assertion that the toxic culture of organic synthesis has been “all but eradicated”.
@BaranLabReads
Baran Lab
4 years
A message to the @scrippsresearch chemistry community from @DonnaBlackmond and Phil regarding the @angew_chem essay posted here for anyone interested on Openflask:
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@ChemBark
ChemBark
2 years
I know humanities majors are probably cheaper, but publishers really need to dish out the extra cash when it comes to hiring people to curate online homework systems.
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@ChemBark
ChemBark
2 years
The Official @ChemBark Odds/Predictions for the 2022 Nobel Prize in Chemistry #ChemNobel
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@ChemBark
ChemBark
3 years
Darth Vader is one of the very few characters in film to portray just how effective and valuable we as disabled people can be to our organizations when supported with the proper adaptive equipment and other reasonable accommodations.
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@ChemBark
ChemBark
2 years
My thoughts are with those speakers (typically, grad students and postdocs) who will be giving talks tomorrow at ACS Chicago to near-empty rooms. It’s not your fault, and you deserve better.
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@ChemBark
ChemBark
3 years
I am no longer a member of the @AmerChemSociety because I now believe this organization does more harm than good to our field. Its iniquitous publishing model that drives librarians and faculty at smaller institutions mad, its absurdly unjustified executive compensation...
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@ChemBark
ChemBark
4 years
You know what I really miss? Two-page @J_A_C_S communications. This format made it easy to keep up with the literature in areas that were not my primary interest. The authors worked hard to distill their major advance to an economy of prose and a few key figures. They were great.
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@ChemBark
ChemBark
2 years
My favorite prank is from grad school, where a classmate from the Jacobsen Lab wrote a full fake JACS comm in proper format and loaded it on the ASAPs page, convincing his labmate that the Trost lab had scooped his enantioselective synthesis of quinine. I still have the PDF.
@beth_halford
Dr Bethany Halford
2 years
Hello #chemtwitter - do you know of any good chemistry April Fool's pranks or stories? I'm thinking of writing an upcoming #Newscripts column about this for @cenmag . Please RT.
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@ChemBark
ChemBark
2 years
First-Year Grad Student: "Do you have any challenging synthesis projects?" Assistant Professor at Scripps:
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@ChemBark
ChemBark
4 years
We apologize for the confusion.
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@ChemBark
ChemBark
4 years
With the Kitty Lawyer story in the news, here is my old account of blowing a Skype interview for a professor position because I appeared as the same kitty (in 2012). It was a DEFAULT setting on Dell's webcam software.
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@ChemBark
ChemBark
2 years
Well worth sharing this again. An absolute treasure. Evans' Chem 206 (Advanced/Graduate Organic) notes
@daddydog22
David A Evans
5 years
MY LECTURE NOTES: YOU MAY ACCESS MY DROPBOX FOLDER:
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@ChemBark
ChemBark
3 years
That molecule is properly named 4-ethenylheptane. This important news did not seem to travel to my friends or the people who publish organic chemistry textbooks. So, to my horror, I have been misleading hundreds of students for the past 7 years with antiquated rules.
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@ChemBark
ChemBark
2 years
I really would like to see JACS release stats on desk rejects broken down by investigator and institutional demographics. I think the community is owed this.
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@ChemBark
ChemBark
3 years
My PhD advisor acted supportive but really wasn’t. One night, I called him to report a tank of chlorine was leaking. He told me to relax and take a few deep breaths.
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@ChemBark
ChemBark
3 years
Instructors of organic chemistry who are interested in updating their lecture materials on alkene nomenclature to reflect the latest changes to IUPAC preferences are welcome to download a relevant slide deck (pptx or pdf) here (near top of page):
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@ChemBark
ChemBark
2 years
M.G. Finn now maybe the chemist closest to two Nobel Prizes without winning one.
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@ChemBark
ChemBark
1 year
Look, Harry Gray is nothing less than a fucking treasure. He is the most enthusiastic and supportive scientific mentor I’ve ever experienced or even heard of.
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@ChemBark
ChemBark
2 years
Just a reminder to all you remaining ACS members that this gentleman is one of the people making over $1M/year at this “non-profit” publishing house and software company masquerading as scientific society.
@cenmag
C&EN (Chemical & Engineering News)
2 years
After nearly 8 years of service, @AmerChemSociety CEO Thomas Connelly will retire at the end of 2022. During his tenure, his accomplishments include the continued growth of the ACS's portfolio of journals and refinement of the organization's core values.
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@ChemBark
ChemBark
3 years
If you began by identifying the longest chain *containing the double bond* and said 3-propylhex-1-ene or 3-propyl-1-hexene, you and I would have agreed last month. That is when I learned that IUPAC changed its nomenclature rules all the way back in 2013 (!)
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@ChemBark
ChemBark
2 years
I can’t remember who’s talk it was, but I will always remember the wonderful line, “That first week, we had collected enough data for three papers: a communication, a full article, and a retraction.”
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@ChemBark
ChemBark
4 years
Now is probably a good time to remind everyone that the ACS is not a scientific society so much as a publishing house where the revenue is used to enrich ACS employees with compensation packages beyond what is customary for a nonprofit organization.
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@ChemBark
ChemBark
4 years
Virginijus Šikšnys has everyone beat as far as most gutting desk rejection of all time.
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@ChemBark
ChemBark
3 years
I observed this relationship between a few labmates in graduate school but we called it something else.
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@ChemBark
ChemBark
4 years
If the pandemic and social distancing have got you down, considering purchasing hydriodic acid from @SigmaAldrich for a quick pick-me-up. It’s the friendliest reagent around.
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@ChemBark
ChemBark
2 years
Every year on the first day of classes, my wife snaps a photo on my way out the door. Happy Academic New Year to everyone who celebrates!
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@ChemBark
ChemBark
2 years
CV/résumé tip: be sure to note “extensive experience with in silica methods” if you use glassware
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@ChemBark
ChemBark
2 years
I woke up at 3 am. I have a recurring nightmare where I’m in the lab finishing an extraction and can’t find sodium or magnesium sulfate anywhere. I hate wet dreams.
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@ChemBark
ChemBark
2 years
If you’re going into organic chemistry for the colors, please don’t. I can send you a pair of my underwear and save you 5+ years of pain in grad school.
@KCGOrtiz
Dr. Ortiz, Your Fave Chemist's Fave Chemist
2 years
"there's so many colors in organic chemistry!!!!" The colors:
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@ChemBark
ChemBark
2 years
E.J. Corey is going to be pissed when he finds out who people think is the "greatest thing to happen to organic chemistry"
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@ChemBark
ChemBark
4 years
Excited to share that twins Corey House Bracher (Fig. 1A) and Woodward Hoffmann Bracher (Fig. 1B) were born on Monday afternoon near ChemBark World Headquarters in St. Louis.
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@ChemBark
ChemBark
2 years
Students: Come. To. Office. Hours. Lecture is like trying to distribute food from the rafters of a supermarket to 100 people waiting below. At office hours, I can get a good look in your basket to make sure you've got all the ingredients you need and your eggs aren't cracked.
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@ChemBark
ChemBark
2 years
Look, I have a Ph.D. in chemistry. I can tell when two people belong together.
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@ChemBark
ChemBark
3 years
Look around your departments. How many labs have hoods that could be used by someone in a wheelchair? How many have NMR instruments that are accessible? Would your boss have tolerated someone chronically ill who could not work 8+ hours/day? Would you?
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@ChemBark
ChemBark
1 year
Tip #72 for avoiding becoming department chair: drop hints you believe all faculty should take a turn teaching first-semester general chemistry
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@ChemBark
ChemBark
3 years
Shared a poignant moment of empathy tonight in IKEA when I found a salesman sitting in the corner in tears. He just had three desks rejected by the editors at @J_A_C_S .
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@ChemBark
ChemBark
3 years
The trouble with writing synthesis problems for exams after chapter 23 in our organic text is that some students find a “creative” way to use Pd coupling reactions for every C-C bond formation. I end up staring at the page wondering how the Heck I should grade it.
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@ChemBark
ChemBark
2 years
It feels *so* much better when a benevolent chemist who is genuinely supportive of students and colleagues is awarded a Nobel than when they give it to a notorious, taskmaster a—hole.
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@ChemBark
ChemBark
2 years
Very sorry to learn of the death of David Evans ( @daddydog22 ). I had the privilege of serving as one of his teaching fellows for Chem 30 at Harvard. As I stated in the Acknowledgments section of my dissertation, his lecture notes are an academic treasure.
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@ChemBark
ChemBark
4 years
There’s a ton of chemistry teachers out there that are having a bigger impact on students than they think they are. Especially so during trying times like the present.
@adchempages
Adrian Dingle Chemistry Educator & Communicator
4 years
There’s a TON of Twitter #chemistry teachers that think they are having a bigger impact on kids than they actually are having. You really are NOT that influential. Really, you’re not. Trust me. #chemed #apchem #apchemistry
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@ChemBark
ChemBark
2 years
Someone needs to learn Hund’s rule and the Pauli exclusion principle.
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@ChemBark
ChemBark
2 years
Students in orgo: now is the time of year you are studying IR spectroscopy. It uses some funny terms (e.g., wagging, rocking, etc.). This is an animation of scissoring. Please be careful searching the web for additional information on scissoring...
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@ChemBark
ChemBark
2 years
It's heartbreaking what is happening to @cenmag . A team of the highest-quality science journalists is being decimated by management, and the mission of the publication is being perverted away from journalism and toward a banal house organ, the extent of which remains to be seen.
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@ChemBark
ChemBark
4 years
While the editors of @J_A_C_S do not publicize it, when anyone has three submissions in a row accepted without revisions, the author goes "on fire" and subsequent submissions are automatically accepted until the next issue is put to bed.
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@ChemBark
ChemBark
4 years
It is not credible for administrators to claim their institution values teaching and research equally when their research faculty have a pathway to tenure while their teaching faculty do not.
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@ChemBark
ChemBark
2 years
@hholdenthorp @nytimes @nyuniversity Is it even true that "Organic chemistry is typically taught as a 'weed-out' class"? I think most orgo instructors try to teach the material with the hope that every student succeeds. If med schools are using it to "weed out" applicants, that's on them, not the teachers.
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@ChemBark
ChemBark
4 years
A stunning advance in femtosecond organic spectroschipy
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@ChemBark
ChemBark
2 years
A chaotic-good idea for your next faculty meeting: professors must recertify their tenure every 10 years by passing undergrad-level tests in general chem, organic, inorganic, physical, biochem, and safety.
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@ChemBark
ChemBark
3 years
I’m not trying to shame anyone. My simple point is that if the plight of disabled chemists is so easily overlooked by most of these organizations, leaders, and allies, what hope is there for meaningful inclusion? I fear the situation is not even slowly getting better, but worse.
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@ChemBark
ChemBark
3 years
@SigmaAldrich It's just 15 minutes later and the Nicolaou Lab has 6 postdocs working on it.
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@ChemBark
ChemBark
3 years
If you’re a chemist who uses a wheelchair and does wet/bench lab work, I’d like to bounce an idea off of you. Email paul.bracher at slu(dot)edu. Other chemtweeps, I’d definitely appreciate this being forwarded to people you know who fit the bill and aren’t on Twitter. Thanks!
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@ChemBark
ChemBark
4 years
I’m not on Twitter a lot, so I missed the “extensive public” aspects of this search. A quick Google search yields a letter that does not appear to be a letter of recommendation.
@J_A_C_S
J. Am. Chem. Soc.
4 years
Following an extensive public search Professor Erick Carreira will be the next Editor-in-Chief of the Journal of the American Chemical Society (JACS), beginning January 2021.
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@ChemBark
ChemBark
3 years
Anyway, sorry to be so negative. But accessibility—like avoiding sexism, racism, and discrimination of LGBTQIA+ chemists—is also something that we should think about more than we do.
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@ChemBark
ChemBark
4 years
Today’s @NobelPrize in Physics just makes me think of how easily Stephen Hawking could have shared it were he still alive. One of the few physically disabled great scientists in the modern era and and inspiration to wheelchair users like me. Can’t help but feel he got shafted.
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@ChemBark
ChemBark
3 years
As the solemn season of Lent begins, I am reminded of the time I was teaching orgo when my wife texted to say we couldn’t have sex that night because “no meat on Fridays”. Her message was projected on the classroom screen because I forgot to silence notifications on my iPad.
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@ChemBark
ChemBark
3 years
Roughly 10.4% of the American workforce is disabled, but only 2.7% of the workforce in science and engineering. Surveys of college freshman suggest disabled students are interested in STEM careers, but this interest does not translate into STEM degrees.
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@ChemBark
ChemBark
2 years
Grad students: it’s a little counterintuitive because talks are perceived as ‘better’ than posters, but if you’re at a conference and want a break, choose to skip a session of talks instead of skipping a poster session. The interaction afforded at posters is *way* undervalued.
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@ChemBark
ChemBark
3 years
It’s not like performing benchwork in organic chemistry is climbing Everest or battling a superhuman mythical beast. Many students with disabilities could do it if given accessible lab space with an accommodating advisor.
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@ChemBark
ChemBark
2 years
I always admired the PhD graduate who referred to our advisor as a “worthy adversary” in the Acknowledgments section of her thesis. I thought that was just about as far as you could go.
@DJGould94
Daniel Gould, MD, PhD
2 years
Let's start an anti-acknowledgement section for manuscripts, where you call out the people who unnecessarily made your life more difficult during the project
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@ChemBark
ChemBark
3 years
As I was wheeled into surgery after a diazomethane explosion in college, the anesthesiologist asked me the last thing I’d eaten. I sheepishly confessed a 1-pound box of Entenmann’s chocolate chip cookies and a quart of 2% milk at 2 am the previous night. A nurse muttered, “Ugh.”
@fuzzymittens
The Annasthesiologist
3 years
You can lie to your parents. You can lie to your boss. You can even lie to yourself. But never, ever lie to your anesthesiologist.
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@ChemBark
ChemBark
3 years
If a disabled student approached you and inquired about joining your lab, would you encourage them? Is your lab space welcoming? Do you have any idea how you’d accommodate someone deaf…paralyzed…blind…chronically ill? Would you secretly hope they’d choose another lab?
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@ChemBark
ChemBark
3 years
Barriers in finding accessible research opportunities could help explain this gap. Look around. In your training, how many disabled students did you encounter? How many talks did you attend where the speaker was disabled? Have you ever met a disabled research-active PI?
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@ChemBark
ChemBark
2 years
The latest “Dear Guido” letter in chemistry…
@chem_christian
Christian Seitz
2 years
Wow Erik it really sounds like you don't realize that students need to publish a thesis and pass departmental exams to graduate. If they don't do this they will be fired. Oh wait - you already told your new students to compete and that you'd fire the losers. nvm @UCSDChemBiochem
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@ChemBark
ChemBark
3 years
What I am asking for here is help. If anyone is teaching with the updated rules: do the following slides look correct? (slides 1-4 of 15)
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@ChemBark
ChemBark
3 years
A lot of PIs don’t even need to be able to perform complex experiments in the laboratory. The most critical skills required of PIs include management, creativity, writing, teaching, mentoring. Yet we base faculty jobs on the experimental productivity of students and postdocs.
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@ChemBark
ChemBark
4 years
I believe in the possibility of redemption of individuals who have made mistakes. But there is a clear "big picture" being painted by these brush strokes. Here are some of the troubling messages our field has sent to young faculty in the last ten years:
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@ChemBark
ChemBark
3 years
My sleeper pick for best book for organic chem instructors is 1992’s “Tandem Organic Reactions” by Ho. It’s not a proper text, but is fantastic inspiration for mechanism problems. Will also titillate those with organic synthesis kinks. What lesser known orgo books are your faves?
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@ChemBark
ChemBark
3 years
We can debate how much attention nomenclature deserves in sophomore organic chemistry, but I will not entertain a debate about teaching incorrect information to students. If there are standards set by IUPAC, we should use them.
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@ChemBark
ChemBark
4 years
My PhD advisor was adamant that nouns never be used as adjectives. He hated compound terms like "flow rate" and reiterated this regularly at our group meetings. So, one time, I asked him during such a meeting if he would order a pizza with pepperoni at the stadium for football.
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@ChemBark
ChemBark
3 years
It is the 5-year anniversary of my greatest accomplishment in life: buying $47.76 dollars worth of TicTacs for $0.24. Sometimes I lie awake at night wondering whether I will ever again feel as good as I did on Orange Friday.
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@ChemBark
ChemBark
4 years
Nothing is going to change anytime soon because this system is self-perpetuating. Those who bought into it and paid their dues now benefit from it. Finally, it’s their turn to run a lab of 15 privileged students with the same mindset and pick the winners. Wash, rinse, repeat.
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@ChemBark
ChemBark
3 years
@Chemjobber Remember kids: never ever pay out of your own pocket to go to grad school in chemistry. You should be the one getting paid (either by your school or your employer).
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@ChemBark
ChemBark
3 years
How did F. Albert Cotton really die?
@SamLemonick
Sam Lemonick
3 years
Hey #chemtwitter what's your favorite unsolved chemistry mystery?
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@ChemBark
ChemBark
2 years
Definitely cations. I can find nothing but positive examples of them.
@ChemistTree
The Chemist Tree 🇨🇦🇸🇬
2 years
What are your favourite ions? #chemistry #science
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@ChemBark
ChemBark
3 years
A few weeks ago, I ran a poll asking whether people had attended a scientific talk given by a speaker in a wheelchair. I imagine the responses were mostly weighted toward chemists, and 91% reported not having seen **one** such talk in the past **10 years**.
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@ChemBark
ChemBark
4 years
I will close by saying to tenured professors in leadership positions (chairs, editors): you know who most of these toxic advisors are. You hear the rumors in hallways and at happy hours. You had classmates in grad school who were wronged by them. Do something more than tweet.
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@ChemBark
ChemBark
1 year
My compromise when teaching named reactions is that I’ll use the names but I’m also going to spill the tea on those who deserve it.
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@ChemBark
ChemBark
2 years
Who's going to tell that big-shot PI that he's a villain in more grad-student stories than he is a hero?
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@ChemBark
ChemBark
4 years
It is the privileged who have the ability to work for little pay. It is the privileged who have the ability to subject their bodies to the stresses of a longer work day. It is the privileged who can bear the short-term opportunity costs of grad school.
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@ChemBark
ChemBark
2 years
When big chemistry textbooks went paperback, I grimaced but capitulated. But now these texts have transitioned to unbound/loose-leaf?! Is this really what students want? I want to have a proper book, not a mess of 800 pages perilously held together in a three-ring binder. Groan.
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@ChemBark
ChemBark
1 year
Paying 149-1. Please bring your tickets to the cashier.
@NobelPrize
The Nobel Prize
1 year
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2023 #NobelPrize in Chemistry to Moungi G. Bawendi, Louis E. Brus and Alexei I. Ekimov “for the discovery and synthesis of quantum dots.”
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@ChemBark
ChemBark
2 years
The first thing I always did when taking a new chem course in college: buy used versions of a different textbook and solutions manual. The first thing I do now teaching a new course: buy 3 pairs. Old editions are a dirt-cheap source of practice problems and alt explanations.
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@ChemBark
ChemBark
2 years
I made some slides (including review slides and a few problems) that demonstrate the updated rules. The ChemDraw structures are embedded and can be edited to suit your taste. Find them here (both PPTX and PDF files) at the top of the page:
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@ChemBark
ChemBark
3 years
When the Hudlický essay came out in June 2020, it was telling how many official statements were released (e.g., from RSC, ACS Publications, and individual PIs) that specifically mentioned avoiding discrimination based on race, gender, and sexual orientation but not disability.
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@ChemBark
ChemBark
3 years
The most exciting day of the year. 📷: My wife, Tara.
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@ChemBark
ChemBark
3 years
Have you ever hosted someone disabled to visit your department? It’s kind of taxing. Did you book an accessible hotel room for them? Is there reliable accessible transportation from the airport and hotel to campus? Is your seminar room accessible? Your workspaces? Restaurants?
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@ChemBark
ChemBark
3 years
On this most sacred week in the liturgical year, I remind myself that entrance to Heaven is determined by a linear combination of h-index, total citations, mean teaching evaluation score (out of 5), and grant expenditures measured in US dollars.
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@ChemBark
ChemBark
2 years
It feels like St. Louis will soon become the #chemtwitter capital of the United States.
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