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Kosuke Inoue Profile
Kosuke Inoue

@ki_endoepi

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Associate Prof: Kyoto Univ, Hakubi, L-Insight fellow, PhD: UCLA, Epidemiology, MD: Univ of Tokyo. Causal Inference, Endocrinology, CVD epi. JST Presto. IJE.

Kyoto, Japan
Joined May 2011
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@ki_endoepi
Kosuke Inoue
1 year
昨年、東大・京大・ハーバード・UCLA・UoM・TXPなどで講演させていただいたHigh-benefit approachの研究が国際疫学会の公式雑誌IJEより出版されました。今後の個別化医療の議論に一石を投じることができたらと思います。
@univkyoto
京都大学
1 year
高血圧診療における次世代の個別化医療戦略を提唱-機械学習により個人の治療効果を予測する時代へ-
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@ki_endoepi
Kosuke Inoue
2 years
因果フォレストという機械学習モデルを用いて「誰をターゲットにCAC(冠動脈石灰化)スクリーニングを行うべきか」について議論した論文が、AHAでの発表に先立ち、Circulationから出版されました!今週Early Career Awardセッションで発表するのでシカゴにいる方は少し覗いていただけると嬉しいです🤗
@ki_endoepi
Kosuke Inoue
2 years
Our new paper is out in Circulation @CircAHA ! We applied #machinelearning causal forest model to uncover the heterogeneity in the association between positive CAC and incident CVD. This will be presented at #AHA22 Early Career Award session! #HTE #grf #CAC
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@ki_endoepi
Kosuke Inoue
2 years
フロントドア基準(FDF)を一般化し、医学研究に応用した論文を出版しました。FDFには因果推論の様々な思想が散りばめられているので、方法論に興味ある方は是非、eTextまで含めご一読いただけますと幸いです。日本語の簡単な解説についてはこちらをご覧ください。
@ki_endoepi
Kosuke Inoue
2 years
Is there an effect of #chronicpain on death mediated through physicians’ #opioid prescriptions💊? To answer this public health question, we extended and applied a generalized form of #FrontdoorFormula in @EpidemiologyLWW . @oacarah @beate_ritz (Thread) 1/
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@ki_endoepi
Kosuke Inoue
1 year
Our new paper @IntJEpidemiol showed that the high-benefit approach (treating🧍‍♀️with high estimated benefit) using #ML #CausalForest outperformed the conventional high-risk approach (treating🧍with high risk) in BP management. (thread) 1/
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@ki_endoepi
Kosuke Inoue
2 years
「因果推論・機械学習の疫学応用」というテーマで、篠崎先生 @she_knows_a_key と原稿を書かせていただきました。TMLE・Causal forestについて簡単にまとめていますので興味ある方はご覧下さい。
@she_knows_a_key
Tomohiro Shinozaki
2 years
『医学のあゆみ』11/19号の井上先生 @ki_endoepi の原稿を枝葉末節部分だけお手伝いさせてもらいました。
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@ki_endoepi
Kosuke Inoue
9 months
Honored to receive MIT Technology Review's Innovators Under 35 Japan Award in 2023!! Hope the high-benefit approach will be one of the key strategies in the future precision medicine & public health era.
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@ki_endoepi
Kosuke Inoue
6 months
Exciting collaboration with @_KSphs !
@_KSphs
Koichiro Shiba
6 months
Excited to announce our new paper in @AmJEpi ! With @ki_endoepi , we discussed how causal forests (and other ML methods for estimating heterogeneous treatment effects) can advance research in population health and health equity, along with practical tips for its implementation.
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@ki_endoepi
Kosuke Inoue
2 years
Is there an effect of #chronicpain on death mediated through physicians’ #opioid prescriptions💊? To answer this public health question, we extended and applied a generalized form of #FrontdoorFormula in @EpidemiologyLWW . @oacarah @beate_ritz (Thread) 1/
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@ki_endoepi
Kosuke Inoue
1 year
Our latest paper led by @naito_tatsuhiko (& @okada_yukinori & Oki-sensei & team!) is out in Circulation @CircAHA ! Hope this #GWAS study advances our understanding and highlights the importance of #PrimaryAldosteronism -common #endocrine disorder as a cause of secondary #HTN .
@naito_tatsuhiko
TatsuhikoNaito
1 year
Our #GWAS paper on primary aldosteronism (PA), the leading cause of secondary hypertension, is published today in Circulation @CircAHA ! Our cross-ancestry study revealed novel risk loci and an unexpectedly large genetic contribution of PA to hypertension.
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@ki_endoepi
Kosuke Inoue
1 year
In our new @JAMANetworkOpen paper, walking ≥8000 steps for 1-2 days/week showed a substantial mortality risk⬇️ as did those who were active more regularly🚶‍♀️.
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@ki_endoepi
Kosuke Inoue
4 years
I’m honored to receive an NIH F99/K00 transition award. This would not have been possible without the help of @beate_ritz , @ER_Mayeda , and Dr. Duru. I also appreciate heartful support from my mentors/collaborators around the world. So excited to keep working on this project.
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@ki_endoepi
Kosuke Inoue
2 years
Honored to present my research at Elizabeth Barrett-Connor Research Award session! #AHA22 #EPI Congratulations to all of our five presenters🎊 Here is a quick overview of my research simultaneously published in Circulation @CircAHA . (thread) 1/
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@ki_endoepi
Kosuke Inoue
2 years
Our new paper is out in Circulation @CircAHA ! We applied #machinelearning causal forest model to uncover the heterogeneity in the association between positive CAC and incident CVD. This will be presented at #AHA22 Early Career Award session! #HTE #grf #CAC
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@ki_endoepi
Kosuke Inoue
4 months
Japanese ver of ME4 is coming soon! いよいよ疫学の聖書が日本語で出版されます。佐藤先生はじめ、監訳された先生方本当にお疲れ様でした🙇‍♂️!
@Shuntarooo3
Sato Shuntaro|佐藤俊太朗
4 months
『Modern Epidemiology, 4th edition』の邦訳『現代疫学』が5/30に出版されます!!!! 圧巻の1308ページ!!!! カバーがかっこいい!!!! Amazonページもできました(予約注文できるようになったらまた告知します). #モダンエピ
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Kosuke Inoue
2 years
Our new research demonstrated the bias amplification feature of adjusting for a perfect/near- instrumental variable in #gcomputation under the time-varying settings. @ki_endoepi @she_knows_a_key @naoki_kondo Dr. Goto.
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@ki_endoepi
Kosuke Inoue
4 months
私を疫学の道へと導いてくださった後藤温先生(横市)と杉山雄大先生(NCGM)との共著です。執筆に際して、多くの先生方にご指導いただき、深く感謝しております!この場を借りて改めて御礼申し上げます。
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@ki_endoepi
Kosuke Inoue
1 year
Happy Spring & New office🌸
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@ki_endoepi
Kosuke Inoue
4 months
@HakubiProject
白眉センター
4 months
井上浩輔 特定准教授(13期 医学研究科)の記事が京都大学広報誌『紅萠』第45号に掲載されました。 一人ひとりに恩恵を。AIを駆使して拓く医療戦略の新地平(コーナー:萌芽のきらめき・結実のとき) @HakubiProject @univkyoto @ki_endoepi
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@ki_endoepi
Kosuke Inoue
2 years
We described increasing socioeconomic disparities in obesity prevalence among US adolescents. Collaboration work with @Dr_KID_ & Roch, and great thread by our first author/rising star, @Ryunosuke_Goto
@Ryunosuke_Goto
Ryunosuke Ryan Goto, MD | 後藤隆之介
2 years
1/ New research published in @JAMAPediatrics with Drs Roch Nianogo, @Dr_KID_ , and @ki_endoepi ! We evaluated the trends in adolescents' obesity prevalence by socioeconomic status in the US.
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Kosuke Inoue
2 years
来年の米国疫学会SER @Portland (6/14-16)のTravel scholarshipの締切は12/9までです!日本在住で応募を検討されている学生・ポスドクは私までご連絡/DMいただけたら幸いです。今回は日本に焦点を当てたセッションも開催されますので、都合つく方は是非奮ってご参加下さい!
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@ki_endoepi
Kosuke Inoue
4 years
Our recent paper was selected as a High Impact Paper for fall 2020 in @HyperAHA ! This study highlights the importance of aldosterone levels (even within the reference range) with respect to the cardiovascular system and overall health. @kewatson
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@ki_endoepi
Kosuke Inoue
2 years
Wonderful time in LA & Chicago🇺🇸, huge thanks to my friends, colleagues, mentors, and family🙏 #SER2022 by @societyforepi was the best conference ever! Will come back soon✈︎ #UCLA #LakeArrowhead
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Kosuke Inoue
3 years
Our recent paper described the concept and application example of Generalizability & Transportability analysis for the general audience. @ki_endoepi @uclawillhsu @oacarah Ashley, Deni, and Alex.
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Kosuke Inoue
10 months
Emphasized the importance of funding opportunities for early career researchers at Japanese-German University Presidents’ Conference (HeKKSaGOn). Even a small amount of money would be helpful to build international networks and start collaborations for larger projects in future!
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@ki_endoepi
Kosuke Inoue
1 year
NHK, 各社新聞、ネットニュースなど日米複数のメディアでも取り上げていただきました。暖かくなってきたのでぜひ週1日からでも歩いてみましょう🤗
@ki_endoepi
Kosuke Inoue
1 year
In our new @JAMANetworkOpen paper, walking ≥8000 steps for 1-2 days/week showed a substantial mortality risk⬇️ as did those who were active more regularly🚶‍♀️.
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@ki_endoepi
Kosuke Inoue
4 years
Our recent work using #NHANES with @AngelaLeung9 , @beate_ritz , @ConnieMRhee showed the #CVD #mediation of the association between #TSH and mortality.
@JAMANetworkOpen
JAMA Network Open
4 years
Cohort study finds even subclinical, mildly elevated TSH levels are associated with all-cause mortality, and cardiovascular disease mediates the association.
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Kosuke Inoue
1 year
なおHigh-benefit approachについては6月の内分泌学会@名古屋とSER @Portland でもお話しする予定なのでいらっしゃる方は是非🤗
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@ki_endoepi
Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA Thank you @DrDudenbostel , @Hyper_AHA , and all who attended this twitter live. This was so intense! I really enjoyed and learned a lot today!! #HYPHIP
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@ki_endoepi
Kosuke Inoue
3 years
Congratulations @oacarah !! Our new president-elect @societyforepi . He is an amazing mentor, researcher, and leader!
@UCLAFSPH
UCLA Fielding School of Public Health
3 years
Dr. Onyebuchi A. Arah ( @oacarah ), #UCLAFSPH professor of epidemiology, has been chosen as president-elect of the Society for Epidemiologic Research ( @societyforepi ). Read more: #epitwitter
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Kosuke Inoue
3 years
@brandimwynne @NakagawaPablo @HyperAHA @DrDudenbostel The most challenging part would be to make clear temporality between these hormones and aldosterone when we tried to see some causal relationship between ald and CVD or CAC. But I would love to see them after this live!! #HYPHIP @HyperAHA @DrDudenbostel
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@ki_endoepi
Kosuke Inoue
3 years
@fjorios @HyperAHA A12. Thank you! Yes, our mediation analysis showed that aldo may increase CVD in both pathways through BP and not through BP. Thus it would be really important to target aldo in addition to BP itself #HYPHIP @HyperAHA @DrDudenbostel
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@ki_endoepi
Kosuke Inoue
6 months
Our @JAMANetworkOpen commentary with @uclawillhsu explores recent thought-provoking work on transportability analysis by Robertson et al. #transportability "Transportability Analysis—A Tool for Extending Trial Results to a Representative Target Population"
@uclawillhsu
William Hsu
6 months
Interesting analysis in @JAMANetworkOpen showing estimated effects from NLST were similar when data was reweighted to match a nationally representative target population. Paper: Commentary on transportability methods w @ki_endoepi :
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA Also, I would love to give special thanks to @TheEndoSociety (SRF) & BWF fellowship which supported my work, my PhD mentors at #UCLA , and all MESA participants, collaborators, staff, and sponsors (including #NIH funding)! #HYPHIP @HyperAHA @DrDudenbostel @ki_endoepi
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Kosuke Inoue
3 years
@DrDudenbostel @fjorios we did not see clear difference in BMI and urinary sodium between those with suppressed renin and unsuppressed renin. This is a little tricky because we are examining general population rather than PA patients #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
Our latest in @IJEeditorial with @beate_ritz @ER_Mayeda @AGOTO_EPI @ytsugawa1 @epi_vahe and Drs. Nianogo, Telesca, Sugiyama, showed increased all-cause mortality risks among people with low HbA1c without DM. Careful monitoring may be needed for them. #hba1c #death #gformula
A recent @IJEeditorial article uses #g -formulas and #machine learning to examine low #HbA1c levels and all-cause or #cardiovascular #mortality among people without #diabetes : #NHANES @ki_endoepi @beate_ritz
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A1-3. In our study, we found that aldosterone was associated with increased risk of subclinical CVD (i.e., higher CAC) and death particularly when renin was suppressed. Moreover, around 45% of this association was mediated by BP↑. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@NakagawaPablo @HyperAHA @DrDudenbostel A14-3. Thus, the question I have is "is the current clinical practice for PA enough to detect people who will have damage due to autonomous aldo secretion?" Will we need to cover more patients (including subclinical PA or even more?). #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@brandimwynne @HyperAHA @DrDudenbostel A7. Interesting question. No, I haven't, but will look at whether we see the associations if variables seem to be available. Thank you! #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A4-3. Thus, before our study, we needed more evidence as to whether aldosterone also plays an important role in CVD pathogenesis among general adults (even without PA or essential HTN). #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A11-1. In general, renin (at least partially) regulates aldo secretion in #RAAS , thus low renin & high aldo indicates autonomous secretion of aldo independent of renin (and suppress renin through negative feedback system) #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@NakagawaPablo @HyperAHA @DrDudenbostel A14-2. At the same time, before jumping to treatment strategy, I think we need more evidence about who we need to think about treatment targeting aldo (e.g., MR) #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@frank_spradley @DrDudenbostel @HyperAHA A9. I am not familiar with this topic, but probably this might be helpful (). I need to search more though, sorry! #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA Hi all, I am a physician-scientist at #KyotoUniv and #UCLA . My background is an #endocrinologist ( #UnivTokyo ) who loves #adrenal and #thyroid glands, and now specializes in #causal modeling in clinical epidemiology as an epidemiologist. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
5 years
@yusuke_tsugawa 困りますよね。自分はグリーンランドのこちらの論文を用いてDefenseすることが多いです。ご参考いただけたら幸いです。
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A1-2. Thus, we investigated the association between Aldo and CAC/death. Given the direct and indirect organ damage of aldo↑, we also estimated the extent to which BP↑ mediated the association. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A4-2. Aldo↑ is associated with many kinds of CVD including heart failure, coronary artery disease, and stoke. However, most of the previous studies have been investigated among people with primary aldosteronism (PA) or essential HTN. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel A3. MESA is a multicenter longitudinal cohort study of adults (45-84 years) free of CVD from 6 communities in the US. Its main goals include the identification of the risk factors for clinical and subclinical CVD progression. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@NakagawaPablo @HyperAHA @DrDudenbostel A10. Base on previous studies, I assume aldo this is not specific to CAC. It would also related to calcification of other arteries but not aware of studies on this topic about people without PA. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@fjorios @HyperAHA A5-1. PA is not a deterministic disorder, and there are people who are between PA and non-PA (including subclinical PA). #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A4-1. Aldo is an essential hormone regulating sodium reabsorption, water retention, and BP. Thus, inappropriately aldo↑ can increase BP, Moreover, excessive stimulation of mineralocorticoid receptor increases CVD risks independent of BP↑. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
Our new research using MESA with the amazing team at UCLA showed the association between elevated urinary stress hormones and incident hypertension/CVD events. Findings highlight the critical role of stress hormones in the pathogenesis of HTN.
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Kosuke Inoue
3 years
@NakagawaPablo @HyperAHA A14-1. Really important point. We can make our findings close to causation using some causal modeling, but it does not tell causality because this is still obs data and suffer from many biases. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
2 years
効果の異質性に着目した個別化医療の実現に向けて様々なプロジェクトを進めているので、興味ある方は是非一緒に研究しましょう!
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A20-2. I am also interested in identifying who we really need to consider treatment/intervention for aldo↑ to prevent CVD (i.e., heterogeneous treatment effects). Any advice & collaboration would be greatly appreciated!! #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@guto_montezano @DrDudenbostel @HyperAHA A6-1. Yes, CAC is "coronary artery calcium" and one of the major markers of subclinical cardiovascular disease. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A11-2. This is one of the major characteristics of primary aldosteronism (PA), the common type of secondary hypertension. Recently, the spectrum of subclinical PA has been established for normotensive persons (). #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
2 years
Honored to receive a paper award from @uja_info (United Japanese Researchers Around the World)! A short presentation will be on May 8th, 10am JST. #UJA 論文賞2022 #Aldosterone #MediationAnalysis
@uja_info
海外日本人研究者ネットワーク(UJA)
2 years
#UJA 論文賞2022 京都大学(留学先UCLA)の井上さんは臨床疫学分野の研究にて見事に受賞されました。おめでとうございます!研究内容や受賞コメントなどは特設サイトをご覧ください。
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Kosuke Inoue
3 years
Lovely figures to describe basic rules of DAG🏃‍♂️ @ki_endoepi @AGOTO_EPI
@igakukaishinbun
医学界新聞
3 years
今回は,因果関係に関する仮説を整理する上で有用なアプローチである「DAG」を解説します。図解された基本事項と具体例を元に,変数の調整を考えていきましょう。 週刊医学界新聞[連載]臨床研究・疫学研究のための因果推論レクチャー(3)(井上浩輔,杉山雄大,後藤温)
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A20-1. Because the present study used a single point of aldo measurements, I am very interested in further investigating the possible cardiovascular burden of dynamic change in aldo (and other hormones) over time. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
AMAZING time to discuss our paper about #aldo and #CAC using #mediation analysis!. Thank you so much for this great opportunity. I learned a lot!! #HYPHIP @HyperAHA @DrDudenbostel @ki_endoepi
@DrDudenbostel
Tanja Dudenbostel, MD, FASH, FAHA
3 years
Today’s fantastic chat is complete and on behalf of @HyperAHA #SoMe Editor team we thank @ki_endoepi for a great discussion and for joining us today! Good luck with ongoing research & we look forward to seeing you join us again for #HYPHIP
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Kosuke Inoue
3 years
@Carmendemigue12 @HyperAHA A21-1. Given that we see the sex difference particularly among adults<60 yrs (Table S1), we assume this difference might be attributed at least in part to difference in sex hormones (i.e. protective effect of estrogen). #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@Carmendemigue12 @HyperAHA @DrDudenbostel A22-2. Also the sensitive to mineralocorticoid receptor may also differ by sex, but definitely further epidemiological and biological studies are needed to understand the potential sex heterogeneity. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@NakagawaPablo @HyperAHA A15-1. I agree with your idea. Although we did not use the measurement of arterial stiffness (e.g., PWV) in our study, several studies have already investigated the association particularly among hypertensive patients, as you know #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
1 year
明日です。興味ある方はご笑覧下さい🤗
@kura_office
京都大学 学術研究展開センター(KURA)
2 years
【イベント情報】 KURA共催でシンポジウム「若手研究者の海外留学・海外転職、再考--パンデミック後の研究キャリア選択」を2023年1月27日(金)に対面・オンライン同時進行のハイブリッド形式で開催します📢 詳細・お申込みはこちらから(要予約)👇
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Kosuke Inoue
3 years
@guto_montezano @DrDudenbostel @HyperAHA ample evidence has shown the relationship between CAC and CVD. e.g., #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A1-1. It has been well known that aldosterone has a key role in the pathogenesis of CVD, but the evidence as to the long-term health outcomes of aldo↑ had been limited particularly among the general population. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
Are physicians who receive industry marketing payments for high-cost 🫀drugs like #PCSK9i more likely to prescribe the drugs? Is the sky blue (on average)? We offer a nuanced take on this controversial topic in @CircOutcomes . (thread) 1/
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Kosuke Inoue
3 years
@brandimwynne @NakagawaPablo @HyperAHA Yes, these topics are really important but were a little beyond the scope of this study. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
5 years
Our new research w/  @liew_zeyan (PI),  @beate_ritz and amazing collaborators in Denmark finds some gestational-week–specific associations between PFAS and TSH in early pregnancy. @EHPonline .
@liew_zeyan
Zeyan Liew
5 years
Credits go to @Koinoue1989 , a talented endocrinologist and a PhD candidate in epidemiology @UCLAFSPH @beate_ritz and the DNBC teams in Denmark @AarhusUni @dceaarhus .
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Kosuke Inoue
3 years
@NakagawaPablo @HyperAHA @DrDudenbostel A15-2. Given a recent meta-analysis of RCT showed the benefit of MR blocker on arterial stiffness (suggesting the critical role of aldo on arterial stiffness (), I believe this mechanism would explain a part of our findings. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A19-3. Not sure about Asian Americans, but ample evidence has shown the CVD burden of aldo↑ among Asians. Thus, I hypothesize that our findings may be applied to all of these racial/ethnic groups but need more studies to validate my hypothesis. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A19-1. A previous MESA study () showed that AA/Black individuals had lower aldo and Hispanics had higher renin. They also showed the association between aldo and SBP only among Hispanics. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
@fjorios @HyperAHA @DrDudenbostel A5-2. Thus we assume some people maynot have PA diagnosis, but mild autonomous aldosterone secretion. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA A19-2. Meanwhile, the Jackson Heart Study (a cohort of AA/Black individuals) showed the association of aldo↑ with SBP (), CVD, and death (). #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
Our new paper linking industry payments with physicians' prescription of insulin was just published in @PLOSMedicine ! Hope this will advance the discussion about the insulin affordability crisis in the US. @ki_endoepi @yusuke_tsugawa @CMM_UCLA @OKenrik
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Kosuke Inoue
1 year
今年のSER @Portland に参加される日本人研究者の方は5/19金までに以下のFormへ記入いただけますと幸いです。 6/15夜にはシンポジストの皆様も囲んで懇親会を予定しています(※出欠確認あり)。ここ数年では最多の日本人出席率なので、色々な刺激を共有できるのが楽しみです!
@ki_endoepi
Kosuke Inoue
1 year
Can't wait to have this international session focusing on #Japan at #SER2023 ! See you in Portland next month.
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Kosuke Inoue
1 year
大学時代からの親友、内藤先生とメンターの岡田先生、鯉党×内分泌で昔からお世話になっている沖先生との共同研究がCirculationから出版されました!臨床・研究に深く携わってきた原発性アルドステロン症の病態解明に貢献することができ光栄です。 プレスリリースはこちら:
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Kosuke Inoue
1 year
Our latest paper led by @naito_tatsuhiko (& @okada_yukinori & Oki-sensei & team!) is out in Circulation @CircAHA ! Hope this #GWAS study advances our understanding and highlights the importance of #PrimaryAldosteronism -common #endocrine disorder as a cause of secondary #HTN .
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA @TheEndoSociety Lastly, this work could not have been done and published without huge help and support from Dr. Watson @kewatson , Dr. Allison, Dr. Goldwater, Dr. Seeman, and Dr. Kestenbaum,. Thank you so much!! #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
2 years
Honored to contribute to this prestigious journal in clinical endocrinology. Thank you very much, @vtangpricha , and all editorial staff of #EndocrinePractice !
@vtangpricha
Vin Tangpricha, MD, PhD
2 years
Thank you top reviewers of #EndocrinePractice including @dclieb @AngelaLeung9 @ki_endoepi Drs Barzilay, Ospina, Lansang, Szalat, Guan, and Grajower
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Kosuke Inoue
3 years
@fjorios @HyperAHA A18. Yes, our data include many people with aldo within the reference range but renin suppressed. Increased CAC even among these people is important for our reconsideration of "what the reference range is" for this nasty hormone. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
1 year
Can't wait to have this international session focusing on #Japan at #SER2023 ! See you in Portland next month.
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Kosuke Inoue
3 years
@asouth_neph @fjorios @HyperAHA @DrDudenbostel Thank you, @asouth_neph !! Yes, one of my PhD thesis topics was how to implement causal modeling (particularly #MediationAnalysis ) in clinically important research questions (related to endo and CVD). #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
2 years
Marvelous work by @YMcardio at #AHA22 with publication in @TheEndoSociety # JCEM. In this meta-analysis, #SGLT2i were associated with incident #T2DM risk⬇️among #prediabetes with #HF or #CKD . SGLT2i might be useful in preventing #DM among such high-risk populations. @univkyoto
@YMcardio
Yuichiro Mori, MD, MPH
2 years
Our recent work was published from #JCEM @EndoSocJournals !. Also presented in #AHA22 . Sodium-Glucose Cotransporter 2 Inhibitors and New-onset Type 2 Diabetes in Adults with Prediabetes: Systematic Review and Meta-analysis of Randomized Controlled Trials
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Kosuke Inoue
3 years
@brandimwynne @NakagawaPablo @HyperAHA A17. We did not analyze the data, but given the weak or null association between aldo and pulse pressure in PA patients, I would assume there won't be significant difference. #HYPHIP @HyperAHA @DrDudenbostel
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Kosuke Inoue
3 years
Congratulations @ER_Mayeda !!
2020 Brian MacMahon Early Career Award Winner Elizabeth Rose Maveda @ER_Mayeda is an assistant professor of epidemiology at @UCLA . Her research interests include racial, ethnic, and other social inequalities in Alzheimer’s disease and methods. Award sponsored by @HarvardChanSPH .
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Kosuke Inoue
2 years
Congratulations on this great achievement Dr. Ritz @beate_ritz ! She has been a wonderful advisor and helped me a lot to build a career path as an epidemiologist. I was so lucky to be her advisee at @UCLAFSPH
Congratulations to #SER2022 Kenneth Rothman Career Accomplishment Award Winner @beate_ritz from @UCLAFSPH ! Award sponsored by @BUSPH
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Kosuke Inoue
3 years
@DrDudenbostel @HyperAHA Thank you very much @DrDudenbostel and @HyperAHA for giving me such a great opportunity!! Looking forward to the discussion about our paper today! #HYPHIP
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Kosuke Inoue
3 years
@georgehret @HyperAHA @DrDudenbostel A2. This is a great point. MESA (the cohort we used for this study) has a standardized protocol to measure CAC.
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Kosuke Inoue
3 years
@guto_montezano @DrDudenbostel @HyperAHA A13. Sorry, I don't have the answer to this. Let me check this after this live and will let you know!
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Kosuke Inoue
4 months
@nishiurah @Toshi_FRKW 本当にたくさんのinsightが散りばめられていて、ずっと聴いていたいご講義でした!
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Kosuke Inoue
3 years
Excited to learn/improve "global insight" with great mentors and colleagues as L-INSIGHT fellow @KyotoU_News over the next several years! #LINSIGHT
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Kosuke Inoue
2 years
@YuyaMatsue 異質性を把握・許容することが、格差を是正するための戦略を考える上で重要だからかなと思いました🤔  #AHA22
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Kosuke Inoue
11 months
Farewell ceremony for #Hakubi researchers 2023. Very inspiring 7 talks!! Congratulations to all presenters & thanks to all attendees. @HakubiProject
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