Ismail Raslan
@itraslan
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@reverendofdoubt @EMHighAK @TheShenger @drjgutt @SkylerLentz @sreeja_natesan @MikePallaci @davidcarr333 @PulmCrit @EMinMiami @Dane_o_MD @rob_cosentini @petrosoniak @skobner @AaronLacyMD @MRamzyDO @pulmtoilet @LWestafer LMWH is the answer 95% of the time. No UFH please!
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@nihardesai89 Educate everyone in healthcare on: how to take a menstrual history, what is non-anemic iron deficiency, and how to treat iron deficiency and heavy menstrual bleeding.
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@BijoyTelivala @ZhuoerXie My first thought but WBC too high and fib is normal… suspect flt3/npm1
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@Ruah_Mahmoud @DrRajivPruthi If you have ready access to factor testing I suggest skipping the mixing study, doesn’t add much. Rosner and Chang % can be helpful but checking for a LAC is faster.
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@richardbuka Or just don’t give it. The rate of TE events in a controlled RCT is 22% in pts not on AC (hint: majority of those with recent ICH). Will likely be higher in real world. Thanks for the great summary.
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RT @richardbuka: Thrombosis rates are much higher in patients receiving high dose andexanet (as are death rates - more on efficacy in next…
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RT @richardbuka: FDA's own review of thrombotic events reported 12 extra cases – 9 in andexanet & 3 in usual care – that were not assigned…
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RT @richardbuka: 1/ FDA hearing on #andexanet alfa is tomorrow (21 Nov 2024). The documents contain some more data on thrombotic events tha…
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👇🏻👇🏻👇🏻 Important key data re annexa-I
Nevertheless, the rate of thrombosis in patients who DID NOT received any anticoagulation was a whopping 26% vs 10% in the usual care arm. The other thing here is that restarting anticoagulation does not prevent events, as we have been led to believe previously.
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