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eriksahailab

@eriksahailab

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we want to find out how life works because we're curious and because we'd like to improve the outlook for cancer patients

Joined May 2020
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@eriksahailab
eriksahailab
4 months
Very pleased to share our latest preprint on MAPK dynamics and cell fate decisions in lung cancer . Does EGFR mutation mean MAPK is always on? NO, it shows dramatic pulses👇1/4
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@eriksahailab
eriksahailab
3 years
Super excited to receive funding from @ERC_Research to understand why tumours look the way they do, and how they might be reorganised to benefit patients. Can't wait to get started. Also, thanks to lab members and colleagues for critiquing the grant.
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@eriksahailab
eriksahailab
3 months
The phrase ‘metastasis accounts for 90% of cancer deaths’ is one of the most widely used in cancer research, yet it is overly simplistic & imprecise. Here we dig deeper into the events leading to cancer mortality 1/2
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@eriksahailab
eriksahailab
2 years
A rare personal tweet: writing this made me reflect on many things. Notably, the amazing love and support I received, and my desire to do the same for both my family and the community of researchers that I am part of. Thank you Mum💛
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@eriksahailab
eriksahailab
4 years
Ever wanted to quantify the patterns in networks? Our tools is now out & free! Designed for the extracellular matrix, but works on F-actin and blood vessels too. Big congratulations to Esther Wershof & the team👏🍾. Tweetorial with non-science examples to follow next week...
@LSAjournal
LifeScienceAlliance
4 years
This work provides a quantitative tool for the analysis of fibrillar patterns in biology. We demonstrate its utility on in vitro generated extracellular matrices, mouse tissues, and patient samples. By Sahai & colleagues @eriksahailab
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@eriksahailab
eriksahailab
4 years
Delighted to share our work imaging metabolic heterogeneity in breast cancer – PI3K, actin, and epigenetics all matter! Big congrats to imaging guru🔬 Hiroshi and @CDHRatcliffe 🍾👏
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@eriksahailab
eriksahailab
3 years
Excited to share new optogenetic and analytical techniques to infer nuclear entry & exit rates of YAP1and bound fractions of proteins of interest @J_Cell_Sci and Key points in linked tweets 👇 1/6
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@eriksahailab
eriksahailab
8 months
Really pleased to share our latest pre-print. We characterise the diversity of matrix patterns in lung cancer using topological data analysis. Moreover, we infer how the matrix & TME change over time. Details below 👇🏽
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@eriksahailab
eriksahailab
2 years
The lab recently turned 18🎉! We can now vote🗳️, drive 🚗(with a licence), and drink🍾 (responsibly, and not in the US). It was great to celebrate with both current and former members. Looking forward to what we might achieve as an adult.
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@eriksahailab
eriksahailab
4 years
The fascination and beauty of art can’t really be quantified, but as scientists we need to quantify the beautiful patterns in nature. Our latest endeavours, together with the code, are available at
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@eriksahailab
eriksahailab
2 years
Now with pretty picture added. Delighted to announce the line-up for the 4th Crick International Cancer Conference @TheCrick Great speakers, numerous short talk opportunities, and we've kept prices low. Hope to see you there!
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@eriksahailab
eriksahailab
1 year
Opportunity to join our team & @TheCrick to work on the tumour microenvironment funded by @ERC_Research Applicants with diverse backgrounds encouraged. Please RT.
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@eriksahailab
eriksahailab
1 year
Q. What happens if YAP1 is lacking from mesenchymal cells? A. Vascular failure. Why? Because vessel formation needs YAP1-dependent tissue stiffening.
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@eriksahailab
eriksahailab
2 years
Please join us @TheCrick in October for our Cancer Symposium. Great line up and lots of opportunities to present and discuss new data. Discounts for students and early registration. Please RT
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@eriksahailab
eriksahailab
3 years
I found my mother’s old nursing text book recently – first edition 1939. Some interesting insights into how knowledge has developed (or not). Parts still look relevant, others reveal the progress in understanding of gene expression and cell metabolism!
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@eriksahailab
eriksahailab
4 years
Both the fun and frustration of research is that you don’t always end up where you planned. We wanted to control YAP-dependent transcription with light, but ended up learning more about its dynamic trafficking
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@eriksahailab
eriksahailab
4 years
Have been trying to suggest reading for new students - this is one of my favourites and pretty timeless Even after two decades, I still feel that I don’t know enough and understand little. And this makes me want to do research.
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@eriksahailab
eriksahailab
4 years
Happy that stromal fibroblasts are so popular. Thanks to all co-authors, @cshlbanbury and @NatureRevCancer
@NatureRevCancer
Nature Reviews Cancer
4 years
Finally (drum-roll please): our most downloaded article of 2020 was a Consensus Statement providing a framework for advancing our understanding of cancer-associated fibroblasts by 29 leaders in the field, led by Erik Sahai @eriksahailab @CSHL @cshlbanbury
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@eriksahailab
eriksahailab
6 months
Excited to share our latest work on cancer cell and fibroblast crosstalk. We derive a signature of stromal communication and unpick why it is bad news in squamous cell carcinoma More details are linked 👇🏽
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@eriksahailab
eriksahailab
4 years
The propensity of cancer to return after many years is devastating; especially for those who relapse, but also for those who live worrying about possible relapse. It is great to see how our understanding of this problem has advanced
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@eriksahailab
eriksahailab
4 years
Hope this leads to more discoveries about CAFs. We started working on them ~15 years ago when we realised they were easier to culture from patient biopsies than the cancer cells!
@XavierTrepat
Xavier Trepat
4 years
We published here a very detailed protocol to co-culture CAFs and Cancer Cells in 3D invasion assays. Led by @seforaconti , Takuya Kato and Anna Labernadie, with @eriksahailab @IBECBarcelona
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@eriksahailab
eriksahailab
4 years
COVID-19 saves you £100! The Crick Cancer Symposium is now free* and will have a hybrid in person & online format on 5&6 October. Sign up to present your data and hear exciting speakers *supply your own tea/coffee+biscuits
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@eriksahailab
eriksahailab
3 years
We are recruiting! If you're looking for scientific adventure, then check out @TheCrick PhD opportunities🎓. And if you want to study cancer + cell migration and like microscopes🔬, then this👉
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@eriksahailab
eriksahailab
3 years
Looking forward to presenting new data & meeting colleagues in Lausanne. First trip since 'you know what' hit. Thanks @unil & @Johanna_A_Joyce for the invitation, and the bonus of a beautiful sunrise over the Alps. Wow!
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@eriksahailab
eriksahailab
3 years
Register for the 3rd @TheCrick International Cancer Conference . Great line-up (see linked tweet) and hybrid format so you can meet up in person. Thanks to our sponsors in person attendance is now only £50 and virtual is free. Please RT
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@eriksahailab
eriksahailab
1 year
Thanks @eLife for plugging our work. Perhaps its just me, but I find cell migration movies endlessly fascinating 🔬
@eLife
eLife - the journal
1 year
Researchers have delved into the factors that determine the invasive patterns of cancers, from thin discontinuous strands to thick ‘pushing’ collectives.
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@eriksahailab
eriksahailab
3 years
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@eriksahailab
eriksahailab
7 months
Am getting excited about the @MetastasisRS meeting. Great speakers lined up. Just over 14 weeks to go. Registration and abstract submission are open - early bird rates are available until end of March 👇🏽 Please RT. Hope to see you there!
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@eriksahailab
eriksahailab
3 years
Ever wanted to know where metastatic cells arise within a primary tumour? Then read this Congrats to all authors🍾👏, especially Xiao who adapted admirably when COVID stopped the experiments feeding his evolutionary models.
@TheCrick
The Crick
3 years
📰 A multidisciplinary team of researchers led by @kevlitchfield at @uclcancer and @TurajlicLab , @SwantonLab and Paul Bates at the Crick has found that the cancer cells in the centre of tumours have the highest chance of spreading around the body.
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@eriksahailab
eriksahailab
3 years
Happy to share this Big credit to Takuya Kato and @jobrenkins at @thecrick for the skillful combination of modelling and experiments. Key findings below
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@eriksahailab
eriksahailab
4 years
Terribly sad to hear of Zena Werb's passing. A pioneering, fearless, kind, amazing scientist and person. She will be missed.
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@eriksahailab
eriksahailab
1 year
10 days left to register for this exciting meeting 👇🏼. Speakers include @MaraShermanLab @nlbigas @SerenaNikZainal @ReiseSousaLab @trevoragraham @ZanivanLab @BatlleLab Val Weaver, Adrienne Boire, Yifat Merbl & more. Would love to see you @TheCrick Pls RT
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@eriksahailab
eriksahailab
4 months
Happy to share this opportunity to join our team. Please apply if you are interested, or re-post if you are not on the look out for a new job
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@eriksahailab
eriksahailab
4 years
Happy to tell you about our latest work on 'dormant' breast cancer cells. Remarkably, the transcriptional state of indolent cells in vivo is phenocopied by interaction with lung epithelial cells in vitro -
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@eriksahailab
eriksahailab
1 year
Opportunity to join our team and collaborate with Helen Byrne to work on computational modelling of the tumour microenvironment @TheCrick @WCMBlog . Thanks to @ERC_Research funding. Applicants with diverse backgrounds encouraged. Please RT.
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@eriksahailab
eriksahailab
3 months
Seeing how smart and committed this group is fills me with hope for the future @MetastasisRS
@MetastasisRS
Metastasis Research Society
3 months
The mission of the MRS Early Career Leadership Council (ECLC) is to support ECRs to establish successful careers in #metastasis research. Here are our wonderful ECRs at the dedicated ECR workshop as part of the MRS 20th biennial congress in London #MRS2024
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@eriksahailab
eriksahailab
3 years
❓What are the best models to study metastasis❓ Join @AlanaWelm and Ilaria Malanchi in a wide-ranging discussion on the pros and cons of different models hosted by @MetastasisRS - 15th Sept, 3pm (UK summer)/10am (US East). Register for FREE
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@eriksahailab
eriksahailab
3 years
Only 5 days left to register for this great conference on cancer imaging at different scales. A key area for both research and clinical advances & also a source of some amazing images. Bursaries from @EACRnews should still be available Please RT
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@eriksahailab
eriksahailab
4 months
Thanks for giving me a bit of airtime with this piece. More importantly, thanks to the @MetastasisRS board and members for continuing to push for a focus on this lethal facet of the disease and initiatives to support trainees.
@MetastasisRS
Metastasis Research Society
4 months
Meet the presidents! We asked the current president of the Metastasis Research Society @MetastasisRS Dr. Erik Sahai @eriksahailab @TheCrick about his research and story with the society. 🧵 1/8
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@eriksahailab
eriksahailab
8 months
Great new work from @EishuHirata in @Dev_Cell ! Astrocytes favour brain metastasis by promoting mGluR1 expression in cancer cells and stabilising EGFR. Interesting therapeutic implications & cool brain TME mimetic culture method too.
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@eriksahailab
eriksahailab
9 months
Happy to add my thoughts to this piece on the importance of the microenvironment
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@eriksahailab
eriksahailab
3 years
A big thank you to PCR for funding us. Looking forward to unlocking the information in extracellular matrix patterns and working out the likelihood of metastatic relapse and who'll benefit most from therapy.
@PCR_News
ProstateCancerResearch
3 years
How can we predict which prostate cancers will return? Dr Anna Wilkins and Dr Erik Sahai at @TheCrick have developed computer software to identify features around prostate cancer cells that mean the cancer is more likely to return. #AI #software #CancerResearch
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@eriksahailab
eriksahailab
2 years
Last few days to register for this great (and cheap) meeting. Hope to see you @TheCrick in early October.
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@eriksahailab
eriksahailab
2 years
Happy to share In brief, collective cancer invasion comes in various forms influenced by MMPs and adherens junctions. Mechanisms that favour wide-strands also promote tumour growth and LN metastasis. 👏🏽 to all authors + 👍🏽 @TheCrick @ERC_Research funding
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@eriksahailab
eriksahailab
2 years
Big congratulations to Alix Le Marois @CultureOfCells for winning an @EmboMolMed poster prize👍🍾. Very well deserved! Thanks also to @CR_UK @TheCrick @AstraZeneca for funding over the years.
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@eriksahailab
eriksahailab
5 months
It was a pleasure, thank you for inviting me.
@QMBCI
Barts Cancer Institute (Queen Mary)
5 months
The day concluded with a fantastic keynote lecture from @eriksahailab @TheCrick , who unpicked how the tumour microenvironment sculpts cancer invasion and therapy resistance. Thank you for joining us Erik! #BCIShowcase24
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@eriksahailab
eriksahailab
3 years
Excited to be giving an in person talk today. Thanks to @cerys_manning & @UoM for the invitation. Have located and checked the batteries in my laser pointer 👍! Will have to remember how to talk🗣️and stand 🧍‍♂️ at the same time…
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@eriksahailab
eriksahailab
3 years
Glad you are enjoying it! Should be another great day tomorrow. Big thanks to @shouval_lab @megeblad @AshaniTW @LeilaAkkari1 @GoetzJacky @IMalanchi @cedricblanpain for amazing talks👏👏
@Othman_Al_Sawaf
Othman Al-Sawaf
3 years
First time attending the #CrickCancerConf @TheCrick (and first in-person conference in ages…) - fantastic program and great speakers!
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@eriksahailab
eriksahailab
3 years
Big wave of nostalgia: post-doc @GiovanniGiangr8 has just shown me a western blot on an x-ray film!!! Can still remember the smell of the dark room and the subsequent elation or despair as you squinted at the film.
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@eriksahailab
eriksahailab
4 months
You did an amazing job with this project. Tracking >28000 cells is a real tour de force!👋
@CultureOfCells
Alix Le Marois
4 months
Very proud to be sharing the pre-print for my work with @eriksahailab on signaling dynamics in EGFR-mutant non-small cell lung cancer! What if MAPK pulsing was driven by endocytic recycling? Read more here:
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@eriksahailab
eriksahailab
3 years
Please check our new work linking spatial growth patterns to cancer evolution @NatureEcoEvo . Congrats & thanks to @XiaoFu90 + @YueZhao97 + all authors - big team effort💪 Tweetorial 👉 See also
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@XiaoFu90
Xiao Fu
3 years
Super excited to share our latest paper in @NatureEcoEvo - Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study.
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@eriksahailab
eriksahailab
3 years
Congrats to all new #AMSFellows2021 👏👩‍⚕️👨‍🔬! Always nice to get nod of recognition from peers, but credit should go to lab members past & present. Looking forward to helping @acmedsci promote biomedical research
@acmedsci
Academy of Medical Sciences
3 years
Congratulations to our 50 new Fellows announced today Find out more about these prominent biomedical and health scientists and see the full list on our website: #AMSFellows2021
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@eriksahailab
eriksahailab
4 years
Just read this excellent review from @MetastasisRS member on the extracellular matrix and cancer. Definitely recommend 👍
@thomasrcox
Thomas R. Cox
4 years
New review in @NatureRevCancer on the importance and role(s) of the extracellular matrix in solid tumours | The Matrix in Cancer | → ← | @TCox_Lab @GarvanInstitute @NatResCancer #extracellularmatrix #ECM #cancer
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@eriksahailab
eriksahailab
2 years
Really looking forward to my visit - both reconnecting with old friends and meeting new colleagues. Just making some last minute adjustments to my slides...
@IRBBarcelona
IRB Barcelona
2 years
📢Tomorrow at #IRBBarcelona we will host Dr. Erik Sahai ( @eriksahailab ) from the @TheCrick . 📌 #BarcelonaBiomed Seminar: 📜"Unpicking How the Tumor Microenvironment Sculpts #Cancer Invasion and Therapy Failure" . ➕info & registrations➡️ @FundacionBBVA
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@eriksahailab
eriksahailab
1 year
Just over a week left to submit an abstract for 4th @TheCrick International Cancer Conference 8-10 Oct. Great speakers and lots of short talk opportunities. Please RT.
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@eriksahailab
eriksahailab
4 years
Like many, I’ve been reflecting on the past year looking for positives. Two things stand out. First, the resilience, adaptability, and hard work of our team. Thank you for covering for each other and still getting papers submitted/re-submitted🧑‍💻 & PhDs awarded👩‍🎓👨‍🎓👍👏. 1/2
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@eriksahailab
eriksahailab
3 years
Delighted to announce the line up for the 3rd Crick International Cancer Conference. Pandemic-permitting this will be an in-person meeting with options for online participation. Meeting 4-5 Oct '21, registration opens May.
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@eriksahailab
eriksahailab
4 years
Delighted that @EishuHirata has published his work on indolent brain metastases👏. Perhaps crystallins are a vulnerability of micro-metastases.
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@eriksahailab
eriksahailab
6 months
Great tweetorial summarising this data-rich study 👇🏽. Lots to enjoy for tumour microenvironment enthusiasts.
@CharlesSwanton
Charles Swanton
6 months
What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24 , out in @CD_AACR today Tweetorial👇
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@eriksahailab
eriksahailab
5 months
Only five days left to register for this great meeting organised by @MetastasisRS
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@eriksahailab
eriksahailab
3 months
We're delighted to host you. Big thanks to @BCRFcure for supporting you and #MRS2024
@HillStirSci
Hillary Andrews, PhD
3 months
MetARP connects advocates and researchers to improve cancer research. Our five pairs are attending #MRS2024 and sharing their experience with one another. A major thank to @MetastaticOdds , @MetastasisRS , and @BCRFcure for making it possible!
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@eriksahailab
eriksahailab
1 year
Thanks to all speakers, especially @Hodivala_Dilke for orchestrating amazing demonstration of stromal barriers using rope🪢, chocolates🍫, a sheet, tubes, and 14 volunteers🧑‍🤝‍🧑🧑🏾‍🤝‍🧑🏽🧑🏽‍🤝‍🧑🏼🧑🏽‍🤝‍🧑🏻🧑🏿‍🤝‍🧑🏽🧑‍🤝‍🧑🧑🏽‍🤝‍🧑🏽!!😃Impossible to do it justice with words.
@Hodivala_Dilke
Hodivala-Dilke Lab
1 year
Wonderful afternoon at @TheCrick with @ErezNeta @eriksahailab @IMalanchi and @JanowitzTobias chatting about the tumour microenvironment #MedicineAtTheCrick
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@eriksahailab
eriksahailab
2 years
Delighted to announce the line-up for the 4th Crick International Cancer Conference @TheCrick Great speakers, numerous short talk opportunities, and we've kept prices low. Hope to see you there!
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@eriksahailab
eriksahailab
4 years
Looking forward to the final day of #VKSTumor21 w/ @shouval @RJDLab and many others. Thanks @KeystoneSymp for making it work in the 'ether'. The one unexpected thing I have missed is giving speakers a heartfelt round of applause👏👏👏
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@eriksahailab
eriksahailab
4 years
join twitter is now crossed off my lockdown todo list
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@eriksahailab
eriksahailab
2 years
Love this single objective light-sheet system 🔬. It sounds to good to be true, but it is the real deal. No more hassle mounting samples + improved throughput 👍. So great and so grateful that @CR_UK are funding this work.
@MACH3Cancer
MACH3Cancer
2 years
The dOPM system can be used for high-speed volumetric imaging or for time-lapse imaging arrays of fixed or live specimens in multi-well plates, e.g. for 3D cancer models. Join us at our launch and tour, Friday 6th May (3:30-6pm). Contact a.kimonyo @imperial .ac.uk for more info.
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@eriksahailab
eriksahailab
2 years
Thanks Julio - I certainly have big shoes to fill.
@JAguirreGhiso
Aguirre-Ghiso Lab
2 years
Our brand new @MetastasisRS President Dr. Erik Sahai @eriksahailab delivering his lecture at our meeting in Buenos Aires. Good luck with your tenure as leader of MRS. It’s been a pleasure working with you these last 2 years.
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@eriksahailab
eriksahailab
4 years
If you’ve ever got frustrated squinting at figures and trying work out why the error bars seem unfeasibly small, or graphs where the p-value doesn't seem to fit with the data plotted, then this is a good read. And full of good advice
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@eriksahailab
eriksahailab
1 year
Come to an afternoon of great talks about the tumour microenvironment @ErezNeta @IMalanchi @Hodivala_Dilke @JanowitzTobias . Both in person and online tickets 🎟️available, and they're FREE 👍🏽 Hope to see you there. Please RT
@TheCrick
The Crick
1 year
🎟️ Free tickets are still available for our #MedicineAtTheCrick event next Thursday! Researchers and clinicians will explore the importance of how cancer cells interplay with their environment, hosted by @eriksahailab @CRUKresearch 📅 29 June 2023
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@eriksahailab
eriksahailab
6 months
4 days left of early bird rates. Top tip - the cost of @MetastasisRS members rate + joining fee is less than the non-members rate. Another reason to join. Hope to see you in London 🇬🇧 this summer * good weather is not guaranteed ☔️🌤️⛈️☀️
@eriksahailab
eriksahailab
7 months
Am getting excited about the @MetastasisRS meeting. Great speakers lined up. Just over 14 weeks to go. Registration and abstract submission are open - early bird rates are available until end of March 👇🏽 Please RT. Hope to see you there!
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@eriksahailab
eriksahailab
3 years
We have an opportunity for a computational/maths summer student. Applications from under-represented backgrounds are encouraged
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@eriksahailab
eriksahailab
3 months
Thanks for making the long journey ✈️✈️. Already looking forward to MRS2026 in Utah 🇺🇸 to be hosted by @AlanaWelm , although hope to catch before then.
@delphine_merino
Delphine Merino
3 months
Some of the Aussie @OzMRS1 crew enjoying sunny London ☀️😃 Thanks @MetastasisRS #MRS24 @eriksahailab and all board members for a fabulous #MRS24 meeting!!!!
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@eriksahailab
eriksahailab
2 years
Ever feel that you are adrift in a sea of data🆘? This review is both a map🗺️and navigational aid🧭. Worth reading👍
@NCIEytanRuppin
Eytan Ruppin, MD, PhD
2 years
What are the big-data analyses that transformed the understanding, diagnosis & treatment decisions of cancer? The next challenges to push this even further? & a compilation of all the major big-data resources to assist in this. Our review's full version:
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@eriksahailab
eriksahailab
1 year
This is really cool and important.
@SamStehbens
Dr. Samantha Stehbens PhD
2 years
Buckle in, it is #microtubule cell migration story time! We reveal a new role for microtubules as cellular sensors which detect and respond to compressive forces, enabling movement and ensuring survival in mechanically demanding environments; just like this little guy squeezing
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@eriksahailab
eriksahailab
4 years
Great to see this work out. Fascinating insight into how stromal HSF1 activation & ECM changes during inflammation promote tumour formation. Big congratulations to @OshratLeviG @shouval @shouval_lab
@NatureComms
Nature Communications
4 years
Stromal HSF1 activation leads to extracellular matrix remodeling associated with colitis-associated colon cancer. #CancerResearch @OshratLeviG @hagargir @Meirav95643474 @MayerShimrit @FriedmanGil @OfraGolani @eriksahailab @DrorShouval @shouval @shouval_lab
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@eriksahailab
eriksahailab
4 years
Do join us - lots of great speakers lined up. Plus side of a virtual Keystone - still great science, cheaper, no jet-lag, low carbon emission👍. Minus side of a virtual Keystone - no fun in the snow 🎿❄️.
@Johanna_A_Joyce
Johanna Joyce
4 years
Join us in late Jan for an exciting convergence of #TumorMicroenvironment and #Metabolism with a wonderful speaker line-up and 16 slots for selected short talks. Still time to apply for scholarships, or submit an ePoster up to Jan 11! @eriksahailab #AlecKimmelman @KeystoneSymp
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@eriksahailab
eriksahailab
8 months
If I was 25 years younger, I'd apply.
@christophertape
Chris Tape
8 months
A few more days left to apply for our new postdoc position. Please reach out if you have any questions!
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@eriksahailab
eriksahailab
2 years
Excited to be catching up with friends and colleagues at #AACR2022 😃 Spoilt for choice with so many amazing talks. Journey was long ✈️✈️, but got to NO last night. Sorry that others weren't so lucky with their travel @gerardevan @JAguirreGhiso ☹️
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@eriksahailab
eriksahailab
4 years
Exciting opportunity to work with @CharlesSwanton Yinyin Yuan @nextdrift and my group please RT
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@eriksahailab
eriksahailab
1 year
Such sad news. Jeff opened my eyes to the world of macrophages when our paths crossed @EinsteinMed twenty years ago. A big influence on many, this paper remains seminal
@MargaretFrame11
Margaret Frame
1 year
Very sad to hear of the death of Edinburgh colleague, Prof Jeffrey Pollard. Jeff was Director of the MRC Centre for Reproductive Health for 10 years after moving from Albert Einstein (NY). He did terrific research on breast cancer, especially the role of macrophages. A huge loss.
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@eriksahailab
eriksahailab
2 years
Worth reading - FAK inhibition 'normalises' the stroma to improve RT responses.
@ElizSMcKenna
Elizabeth McKenna
2 years
Now online in @CD_AACR : Stromal Reprogramming by FAK Inhibition Overcomes #RadiationTherapy Resistance to Allow for Immune Priming and Response to Checkpoint Blockade @DeNardoLabWUSM @WUSTLmed @SitemanCenter #PancreaticCancer #Immunotherapy
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@eriksahailab
eriksahailab
6 months
Delighted to see published. Lots to unpick, but the highlight is the uncovering links between neutrophil-rich TME, PIK3CA, and bad outcomes, especially in LUSC. Congrats to @EnfieldKatey @ColliverEmma @MihaelaAngel0va and all authors.
@CharlesSwanton
Charles Swanton
6 months
What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24 , out in @CD_AACR today Tweetorial👇
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@eriksahailab
eriksahailab
4 years
Thanks to all the speakers - @MVHlab @Johanna_A_Joyce @lyssiotis @MichaelPacold et al - and participants for a great day one of #VKSTumor21 . There is even a small dusting of snow in London to re-create the Keystone vibe for me. Looking forward to more exciting talks tomorrow!
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@eriksahailab
eriksahailab
6 months
I'm excited to be visiting. See you very shortly.
@roose_jeroen
Roose Lab UCSF
6 months
We are excited about seminars by @TMEM_Samuel and @eriksahailab tomorrow morning in our @TheMarkFdn Endeavor program @UCSFCancer @UCSF . Thank you, Michael & Erik for stopping by.
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@eriksahailab
eriksahailab
2 years
Delighted to welcome such a talented bunch to the MRS. Looking forward to working together.
@JAguirreGhiso
Aguirre-Ghiso Lab
2 years
@MetastasisRS Congrats to all our new board members @LeahCookPhD @valientelab @johannaivaska @lab_bcm @EishuHirata & Officers Rajeev Samant and @BravoCorderoLab for their appointment! And special congrats from @eriksahailab & me to @AlanaWelm , our new Incoming President Elect!
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@eriksahailab
eriksahailab
4 years
Do check out this exciting meeting organised by @EACRnews and @myESOI on imaging cancer at different scales in both model systems and patients
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@eriksahailab
eriksahailab
1 year
Many congratulations Colin!👏🏽 Well deserved. Looking forward to exciting insights into improving targeted therapy in breast cancer working with you, @EACRnews , @AstraZeneca , & @MACH3Cancer
@EACRnews
EACR
1 year
🎉 Colin Ratcliffe has been announced as the first recipient of an EACR-AstraZeneca Postdoctoral Fellowship, funding that is awarded for a period of up to 3 years to support excellent postdoc researchers in laboratories throughout Europe and the world:
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@eriksahailab
eriksahailab
2 years
Delighted that the MRS is able to support trainees presenting at meetings 👇🏽 If you're not already a member there is plenty of time to join before the deadline for travel bursary applications.
@MetastasisRS
Metastasis Research Society
2 years
The MRS board is pleased to announce the establishment of our Travel Bursaries program for Early Career Researchers to attend national & international metastasis conferences. More details can be found here: | First deadline is 24th March 2023 #metastasis
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@eriksahailab
eriksahailab
4 years
Intriguing work getting under the bonnet/hood of AI to predict metastatic capability - it comes back to cell protrusions
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@eriksahailab
eriksahailab
2 years
Great opportunity to set up your own lab @TheCrick 👇
@TheCrick
The Crick
2 years
Come start your group at the Crick! 💡 We're looking for creative researchers from all areas of biology and biomedicine to join our early career faculty community. #AcademicJobs | #ECRChat Learn more and apply by 6 October ⤵️
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@eriksahailab
eriksahailab
1 year
This is a great scheme. If you're not an MRS member then you can join and be eligible straight away 👍🏽
@MetastasisRS
Metastasis Research Society
1 year
Applications are open for the next round of MRS Travel Awards. More info on eligibility and how to apply can be found here: | Deadline is 24th Sept 2023 #metastasis #ECR
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@eriksahailab
eriksahailab
4 years
Second, the amazing results that can be achieved by scientists👨‍🔬 and clinicians🩺 work together. Plenty of COVID-related examples in 2020💉, but this from a few years back remains one of the most inspiring papers that I have ever read 2/2
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@eriksahailab
eriksahailab
1 year
Well done Colin! Now you can enjoy the rest of the conference.
@CDHRatcliffe
Colin Ratcliffe
1 year
Thank you for the opportunity to speak at #EACR2023 and present my organoid work from the @eriksahailab . @MACH3Cancer @AstraZeneca @TheCrick @EACRnews
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