Josette Schoenmakers
@JosetteSchoenma
Followers
7,487
Following
396
Media
5,292
Statuses
32,592
Explore trending content on Musk Viewer
ジャンプ
• 186853 Tweets
JUMP
• 138418 Tweets
FOURTH COMEBACK
• 135463 Tweets
ACTRESS ENGFA FIRST MOVIE
• 115287 Tweets
#CDTVライブライブ
• 114686 Tweets
あと5話
• 112268 Tweets
呪術完結
• 100088 Tweets
HUNTER×HUNTER
• 88275 Tweets
大社高校
• 84849 Tweets
神村学園
• 69882 Tweets
KARA
• 61987 Tweets
#音が出たら負け
• 38382 Tweets
#INZMフルZM
• 33633 Tweets
1st MV OF POND
• 31650 Tweets
カウントダウン
• 29514 Tweets
カミガタ
• 27090 Tweets
GEMN
• 26979 Tweets
#海のはじまり
• 25968 Tweets
Gege
• 25745 Tweets
ゲリラ豪雨
• 25542 Tweets
紫耀くん
• 24264 Tweets
ハンターハンター
• 22477 Tweets
familie
• 21330 Tweets
ズマズマ
• 20053 Tweets
キタニタツヤ
• 16600 Tweets
残り5話
• 15858 Tweets
ファタール
• 13643 Tweets
土砂降り
• 12760 Tweets
海ちゃん
• 12117 Tweets
Aqua Timez
• 11747 Tweets
エンティーム
• 11278 Tweets
サラスト
• 10710 Tweets
Pinned Tweet
FLiRT (JN.1* met F456L+R346T), zelfs diegene met een extra S31del mutatie, zijn al een tijdje op hun retour.
KP.3 is al een tijdje dominant en ik verwacht dat nu, week 31, KP.3 met extra S31del mutatie (KP.3.1.1) de scepter zwaait!
3
25
65
We have an unprecedented situation in the Netherlands.
JN.1 is probably taking over this week, which is expected to boost cases.
But at the same time sewage concentrations of SARS-CoV-2 are already climbing and near an all time high.
Ideal for co-infections and recombinants!
26
188
456
Here we go!
A dominant BA.2 in Denmark on the 9th of January 2022.
2 days later than I predicted and maybe some extra when data will be complete. But the 2k samples available on the 7th, make it quite clear were it was going already, if you ask me.
I still dare say BA.2 has become the dominant variant in Denmark in the last couple of days!
(But I accidentally removed my last tweet about it 🙃).
Newest graphs based on
@GISAID
data here, based on 700+ samples on the 2nd of January)
7
44
106
35
173
421
XBB.1.5 is not the only fastly growing variant we should be keeping an eye on!
Fortunately Denmark is still sequencing a lot of samples fast. Around 3k per week!
Plus, they have many of those variants around.
A 🧵 on BR.2.1, CH.1.1(.1), XAY.2, XBB.1.5, XBC.1, XBF and XBK!
1/6
9
163
420
Denmark:
"Preliminary calculations indicate that BA.2 is one and a half times more contagious than BA.1."
18
178
372
OMT-lid Menno de Jong zegt net bij Eenvandaag dat ze bij het screenen van een paar honderd positieve samples, vorige week maandag 2,5% Omicron vonden, afgelopen maandag bijna 12% en gisteren (woensdag) bijna 25%!!!
57
143
342
We jumped to 74 BA.2.86!
A first for (Western) Australia and Spain. A new one for France, Canada and Israel. 2 new ones for Scotland and the USA (Pennsylvania and Colorado).
26 for England, which have a combined new mutation (G2527A), which indicates (a) cluster(s).
1/2
We are at 39 BA.2.86.
3 new ones from England and 1 from Israel. All from the "European" branch. My compliments on very fast sequencing!
I altered the Sc2rf output to compare the samples with basic BA.2.86 and to have more space for sample details. I removed likely artrfacts.
6
90
260
16
120
338
I made some new charts, since BA.2 has now clearly passed BA.1 in Denmark.
Delta seems to be reduced to less than 1% since 13th of January.
I cut of the last 3 days, because I think those days will change when more data comes in.
Here we go!
A dominant BA.2 in Denmark on the 9th of January 2022.
2 days later than I predicted and maybe some extra when data will be complete. But the 2k samples available on the 7th, make it quite clear were it was going already, if you ask me.
35
173
421
7
102
269
We are at 39 BA.2.86.
3 new ones from England and 1 from Israel. All from the "European" branch. My compliments on very fast sequencing!
I altered the Sc2rf output to compare the samples with basic BA.2.86 and to have more space for sample details. I removed likely artrfacts.
35 BA.2.86.
New ones from Denmark (2), France and Scotland.
13
55
191
6
90
260
This EG.5.1.1(HK)/JN.1 recombinant has been designated and is called XDD.
It has a JN.1 Spike, but 2 parts of HK at the outer parts of its genome.
Only 4 samples for now, but all recent and from 3 different countries.
Let's see where it goes!
7
76
238
We are at 24 BA.2.86.
Denmark 10
Sweden 4
USA 3 of which 1 traveler from Japan
Portugal, South Africa 2
Israël, England, Canada* 1
Newest al from mentioned branch.
Tree not completely correct, but still handy for dates etc..
Recent extra Spike mutations S:T299I and S:E748Q
21 already, with extra ones from Denmark and Sweden with extra N and Spike mutations. I will tweet more details when they stopped pouring in every few minutes...
11
42
153
7
78
219
Zouden jullie deze informatie aan willen passen
@NOS
? Het aantal ziekenhuisopnames in Denemarken blijft niet dalen, dat aantal stijgt juist juist gewoon door. En is zelfs hoger onder 0-2 jarigen dan onder 80-plussers (waar het ook niet bepaald laag is).
11
63
203
Aangezien ik denk dat we aan het begin van een gigantische JN.1 (BA.2.86.1.1) Corona besmettingsgolf zitten, wil ik er nog even op wijzen dat iedereen (behalve heel jonge kinderen?) nu een vaccinatie kan halen.
Vaak zelfs zonder afspraak.
Zie
@GGDGHORNL
@VerzWrk
@anatwitje
De coronaprik is niet voor iedereen nodig. Behoor je niet tot de doelgroepen, maar wil je vanwege een kwetsbaar gezinslid of op advies van een behandelend arts toch de coronaprik, dan kan je een afspraak maken. De GGD'en doen geen triage op de locaties.
15
13
19
112
110
198
35 BA.2.86.
New ones from Denmark (2), France and Scotland.
31 BA.2.86
New ones from Sweden, France (1st) and Scotland.
4
50
149
13
55
191
JN.1 seems to be already dominant in Iceland and the fastest in France, Denmark and Canada as well!
I have cut off weeks that are probably less then half complete. Be aware that for Iceland, France and Canada that still means that the most recent week is incomplete.
9
84
193
About 3.5k new sequences from Denmark were uploaded to
@GISAID
today. BA.2 is still growing faster there than the most common Omicron (BA.1)!
I really hope this variant is going to be included (separately) in all kinds of studies that are going on.
Latest weeks incomplete!
I just made a new overview, since new BA.2 data are coming in extremely fast on
@GISAID
, especially from Denmark. Could somebody please tell me there is a huge bias in those data, because otherwise we have a variant on our hands that's growing even faster than BA.1 (both Omicron)
3
14
64
15
56
185
Great work!
Immune evasion by XBB.1.5, even after 3 mRNA vaccins plus a BA.5 infection.
Detailed information for the experiments described here can be found in the newly uploaded preprint:
11
76
195
9
63
176
2 more "representative" BA.2.86 samples from Portugal with the A613G mutation. From the 15th of August, which makes them the most recently found.
So 13 now, from 6 different countries.
It seems to miss S:R403K. Artifact?
And T11614C and C17288T=ORF1B:T1274I as extra mutations.
Indeed. The 11th BA.2.86 from Ohio has a A6183G=ORF1ab:K1973R mutation, like the English and 2 out of 3 Danish samples.
As far as I can see, all the other mutations it has are shared with all the other BA.2.86. Which makes sense, because it is one of the oldest samples found.
0
11
50
6
70
177
Because I think India is too big a country, I have analysed some of its provences.
Gujarat: BA.2.75 from 1 to 9% in 3 weeks, BA.5 fluctuating around 7%
Maharashtra: BA.2.75 from 0 to 60% in 4 weeks, BA.5 stable around 3%
Tamil Nadu: only 1 BA.2.75, BA.5 grown from 18 to 60%
>>
11
47
172
As numbers are going up in New South Wales and other parts of Australia, I want to tell you about the newly designated and fastly growing BR.2.1.
BR.2.1 = BR.2.75.4.2.1
It is a BA.2.75 with 3 extra spike mutations (L452R, F486I, R346T (sometimes reversed)), plus ORF8:S67F.
1/6
New COVID-19 update from NSW Chief Health Officer, Dr Kerry Chant.
This week’s surveillance report can be found on our website:
64
23
64
7
69
170
26 BA.2.86 now.
New ones from England and Scotland from the 16th of August.
I used good old Sc2rf to show the mutations.
You can read the nucleotide from top to bottom, see the original in black and a different letter in red underneath if BA.2 already had the mutated version.
We are at 24 BA.2.86.
Denmark 10
Sweden 4
USA 3 of which 1 traveler from Japan
Portugal, South Africa 2
Israël, England, Canada* 1
Newest al from mentioned branch.
Tree not completely correct, but still handy for dates etc..
Recent extra Spike mutations S:T299I and S:E748Q
7
78
219
6
46
164
An immunocompromised man, who was chronically infected with BA.1.17 for more then 1,5 years, until unfortunately he died because of his underlying disease, was tested repeatly. 50 nucleotides mutated
Big thanks to this patiënt and to Magda Vergouwe,
@Viroloog
,
@Flahless1
et al.
Nederlandse man had 613 dagen corona, virus muteerde meer dan vijftig keer
166
40
142
5
45
164
BQ.1* and BQ.1.1 are growing fast in Europe. XBB in Asia.
BQ.1.1 seems faster than BQ.1 worldwide.
I included BQ.1* in these charts though, because it becoming dominant will have an impact on case numbers. And it includes some other sublineages that might be fast, like BQ.1.8.>
2
62
159
@rivm
@mauricebre
Jawel hoor, alleen noemen jullie alles Delta. En moesten ze tot aan vandaag gevonden worden door naar 2 specifieke mutaties te zoeken, omdat de naam AY.4.2. nog aan de samples toegekend moest worden.
Bij deze dan de primeur (wat eigenlijk geen primeur is).
10
22
157
@chrischirp
New faster variants, one after the other. That's what's going on. Just like in the rest of the world.
(Plus waning vaccine effectivity probably, which many countries are (consciously) not fixing!)
Purple: CH.1.1*, green: XBB.1.5, Orange: XBB.1.9*
Graph: CovSpectrum.
8
57
159
Et voilà!
We hebben in Nederland inmiddels 2 SARS-CoV-2 dagrecords in het riool, maar nog net geen weekrecord. Maar dat kan nooit lang meer duren.
In het tweede figuur zie je het weekrecord. Dat was tijdens de BA.2 golf, begin maart 2022.
13
30
97
19
54
154
21 already, with extra ones from Denmark and Sweden with extra N and Spike mutations. I will tweet more details when they stopped pouring in every few minutes...
3 BA.2.86 from Sweden.
1 from Stockholm (7th of August), 2 from Vasternorrland (18th, 19th).
Again from the A6183G, C12815T branch, but with an extra A2127G. One has S:S1249P extra.
That makes it 16 from 8 countries probably. (I forgot 1 US one came from a traveler from Japan)
8
67
143
11
42
153
84 BA.2.86 now, because of 10 new ones from South Africa.
Gauteng 6
Mpumalanga 3
North West 1
In total since the 15th of July, 13 out of 103 samples were BA.2.86 in SA.
8/57, 3/3 and 1/1 for the 3 provences resp.!
Please note how different this chart looks. No cluster!
We jumped to 74 BA.2.86!
A first for (Western) Australia and Spain. A new one for France, Canada and Israel. 2 new ones for Scotland and the USA (Pennsylvania and Colorado).
26 for England, which have a combined new mutation (G2527A), which indicates (a) cluster(s).
1/2
16
120
338
4
62
151
31 BA.2.86
New ones from Sweden, France (1st) and Scotland.
I miscounted. 27. Thanks
@CovidSafeNZ
!
But 28 already, because of a new South African one (from Gauteng) from the 17th of August. Thanks
@OliasDave
!
6
44
126
4
50
149
Petitie van huisartsen!
Morgen 19 juli laatste dag.
Stel de overgebleven vaccins beschikbaar aan COVAX
8
141
144
Hier zakt mijn broek toch wel van af, hoor. Een maand lang hoor je amper wat van het RIVM over BA.2 en dan komen ze uiteindelijk als eerste hiermee?
'Deze subvariant is besmettelijker, wat kan betekenen dat de besmettingspiek mogelijk vroeger zal komen'
34
40
144
3 BA.2.86 from Sweden.
1 from Stockholm (7th of August), 2 from Vasternorrland (18th, 19th).
Again from the A6183G, C12815T branch, but with an extra A2127G. One has S:S1249P extra.
That makes it 16 from 8 countries probably. (I forgot 1 US one came from a traveler from Japan)
2 more "representative" BA.2.86 samples from Portugal with the A613G mutation. From the 15th of August, which makes them the most recently found.
So 13 now, from 6 different countries.
It seems to miss S:R403K. Artifact?
And T11614C and C17288T=ORF1B:T1274I as extra mutations.
6
70
177
8
67
143
New graphs.
Picking countries that sequence fast, because a few weeks make a big difference!
Week 37 for England and especially week 38 for Denmark and Belgium are still preliminary.
England en Denmark both just got their first XBB!
Btw, not the only growing sublineages around
Hopefully this will demonstrate how crazy the battle between various variants/sublineages is right now. 😳
A selection even!
XBB is a BM.1.1.1/BJ.1 recombinant. BM.1.1.1 is a BA.2.75 sublineage and BJ.1 is BA.2.10.1.1.
BQ.1 = BA.5.3.1.1.1.1.1
Week 37 is preliminary!
4
28
90
9
52
143
Wat een ontzettend slechte timing!
Je hebt kans dat hierdoor al die carnavalsvierders, die deze week positief zijn, maar alvast de isolatie gaan laten varen. En dat terwijl deze golf nog opwaarts gaat en we helemaal niet weten of de vaccins niet al te lang geleden gegeven zijn.
Corona volgens OMT nu een alledaagse infectie: 'Schrap testen en isolatie'
3
2
2
10
34
142
I am not as sure about FLiRT becoming the dominant one, as I was before
The competion is growing, especially KP.3 (F456L+Q493E, no R346T), which is not surprising seeing that
@yunlong_cao
found it most immune evasive and
@BenjMurrell
found it to have the biggest growth advantage
Since we just started week 15, I think these graphs could be telling us that in several countries in the world JN.1 plus S:R346T and S:F456T (
#FLiRT
) has reached or will soon reach 50%.
Therefore spring waves might be starting.
Be aware! Data of recent weeks is often incomplete
8
46
132
7
43
140
@NOS
Jullie vergeten er bij te vertellen dat wij in Nederland dit vaccin niet krijgen!
Maar in plaats daarvan een vaccin dat gebaseerd is op de BA.1.
9
40
138
'Kuipers wil dat eerste Kamer terugkomt van reces om coronamaatregelen China'
1- Hypocriet om China op te voeren, omdat ze nu doen wat wij allang deden.
2-En dat terwijl we zelf niet eens de kiemsurveillence op orde hebben!
Een schoffering naar de GGD en labs die sequencen!🧵
8
55
138
I miscounted. 27. Thanks
@CovidSafeNZ
!
But 28 already, because of a new South African one (from Gauteng) from the 17th of August. Thanks
@OliasDave
!
26 BA.2.86 now.
New ones from England and Scotland from the 16th of August.
I used good old Sc2rf to show the mutations.
You can read the nucleotide from top to bottom, see the original in black and a different letter in red underneath if BA.2 already had the mutated version.
6
46
164
6
44
126
Please notice that the blood from 19 out of 27 vaccinated subjects, that had had one breakthrough infection, did not show any sign of neutralising BA.2.86.
This was the case for 4 out of 54 vaccinated subjects that had had 2 breakthrough infections.
Sharing some new experimental data on BA.2.86:
1) BA.2.86 is antigenically distinct compared to XBB.1.5.
2) BA.2.86 can significantly escape XBB-infection/vaccination induced antibodies.
3) However, the infectivity of BA.2.86 may be much lower than XBB.1.5 and EG.5. (1/n)
59
620
2K
8
45
134
🤯
Ik dacht dat we dat inmiddels wel achter ons hadden gelaten, dat fabeltje dat kinderen bijna nooit ziek zouden worden van Corona.
En al die kinderen met RSV in het ziekenhuis, waar zijn hun 1000x zoveel 'antistofcellen' dan gebleven?
Waarom worden kinderen bijna nooit ziek van corona? Omdat hun afweersysteem fantastisch werkt. Zij kunnen tot wel 1000 x sneller antistoffen aanmaken dan mensen boven de 60. Zo hebben ze veel meer antistoffen paraat dan volwassenen..
#CoronaCollege
405
37
82
15
36
132
Since we just started week 15, I think these graphs could be telling us that in several countries in the world JN.1 plus S:R346T and S:F456T (
#FLiRT
) has reached or will soon reach 50%.
Therefore spring waves might be starting.
Be aware! Data of recent weeks is often incomplete
8
46
132
I think European countries should not only keep an eye on XBB.1.16, but on XBB.2.3 as well.
XBB.1.16 might be a bit faster, but XBB.2.3 seems to still be a little ahead (depending on the country).
@HarrySpoelstra
@Emmanuel_microb
True.
In the Netherlands 7 XBB.1.16 and 27 XBB.2.3 have been found so far.
In Belgium 2 XBB.1.16 and also 27 XBB.2.3, I think.
XBB.2.3 does not seem to grow when XBB.1.16 is already dominant, but if not, it might be different.
Note: last week NSW is still prelimary!
2
11
26
1
47
130
A huge jump to 7% in Amsterdam for BA.4/5 (L452R)!
For comparison, only 6/1861 samples on GISAID since the 10th of April have that mutation of which 4 were BA.4 and only 1 BA.5.
Be aware that mostly vulnerable people and their caretakers, plus those unboostered, get tested now.
A total of 181 randomly selected SARS-CoV-2 positive samples, collected 2nd&4th May 2022 at
@GGDAmsterdam
testing facilities, 0/181(0%) indicated a BA.1-like, 168/181(93%) a BA.2-like and 13/181(7%) a BA.4/5-like variant. Thanks to
@amsterdamumc
&
@inBiome
.
1
36
74
6
56
130
Wat vreselijk jammer!
Naast dat we nog geen flauw idee hebben hoe hoog deze (XBB met S:F486P) golf gaat worden, mede door de afnemende effectiviteit van de vaccins, krijgen we door een Omicron infectie waarschijnlijk amper een booster van onze antistoffen tegen Delta etc..
18
23
130
Found in the Netherlands, France, England and Iceland.
I just realized that there is already a BA.2.86.1 sublineage with a mutation in this spot (L455S). There are only 4 sequence (from 4 different countries), but I bet there will be many more. This is almost certainly a class-1 escape mutation. Last hurdle.
4/
7
101
541
1
26
130
New hospitalizations do not form a plateau any longer in the Netherlands (bottom graph).
Source: from
@kalahiri
We have an unprecedented situation in the Netherlands.
JN.1 is probably taking over this week, which is expected to boost cases.
But at the same time sewage concentrations of SARS-CoV-2 are already climbing and near an all time high.
Ideal for co-infections and recombinants!
26
188
456
4
49
129
This is quite extraordinary.
We had another Delta/Omicron recombinant XAY.2 approaching 6% in Denmark recently, but 30% and rising!
I thought it might be a reflection of XBC putting more people in hospital and testing/sequencing going down, except in hospitalised, but ...
1/2
XBC.1.6 could be behind a wave in South Australia it is around 30% of samples after 15th of March.
@trvrb
@firefoxx66
@PeacockFlu
@CorneliusRoemer
@Rajeev_The_King
@NathanGrubaugh
@dfocosi
@EmMicucci
@EllingUlrich
@MoritzGerstung
@tom_wenseleers
2
18
68
3
47
125
There is some discussion going on about where BR.2.1 came from.
Spoiler: most likely IMO, New South Wales / Australia
Let me give some extra info. 🧵
BR.2 = BA.2.75 that subsequently gained spike mutations L452R (BA.2.75.4), R346T and F486I
BR.2.1 = BR.2 plus extra ORF8:S67F
10
47
126
Gisteren leek het al de hoogste maandag in lange tijd, maar met deze dinsdag erbij denk ik dat het hogere aantal nieuwe ziekenhuisopnames geen toeval meer is.
Met dank aan
@kalahiri
, die de website up to date houdt!
Dit is niet eerder voorgekomen
Een nieuwe duidelijk snellere variant, die het overneemt op een moment dat de rioolwaarden (en dus waarschijnlijk het aantal infecties) nog duidelijk aan het stijgen zijn EN op een zeer hoge waarde zitten
Wat zal dit doen met de ziekenhuisopnames?
38
52
111
16
55
127
This tenth BA.2.86 has an extra C21T, T4579A and S:G594S mutation. The one at the bottom of the top branch.
One more BA.2.86 case have been found, increasing the number of Danish cases detected in Denmark to 4.
3
43
106
6
35
125
Een nieuw dieptepunt is bereikt.
Er komt inmiddels meer info over onze varianten uit de USA en Zuid-Korea, die reizigers testen, dan van het
@rivm
.
31 samples op GISAID voor week 20/21. 14 van het
@amsterdamumc
, 9 uit het buitenland en 8 van het RIVM.
1/2
8
41
126
"2 tot 3 weken beschermd'
Nét hersteld, raak je weer besmet: met omikron lijkt het te kunnen"
"Volgens het onderzoek kun je op dit moment – als je niet bent geboosterd – heel snel na je laatste infectie herbesmet raken met omikron."
19
61
126
Dus:
Dag 1: De Delta oplopen
Dag 3: Janssen vaccinatie halen
Dag 4: Naar de disco, met fellow net gevaccineerden, zonder 1,5m afstand (maar wel met gewassen handen!)
Dag 5: Beetje hoofdpijn. Het zal wel een kater zijn..
What could possibly go wrong?
13
49
120
Surprise! 😉
Besides the title, this is one of the best written and complete pieces about BA.2 I've read so far.
'Sudden rise of more transmissible form of Omicron catches scientists by surprise'
10
37
124
The 3rd Danish BA.2.86 has been uploaded to GISAID. 🙏
It looks very similar to the earlier Danish and the English sample.
New one at the bottom.
EPI_ISL_18114953
Collected on the 7th of August 2023.
BA.2.86. Three cases of the new SARS-CoV-2 variant now detected in Denmark. The subvariant differs significantly from the other omicron variants that have been seen in the past, and it is designated as ‘Variant under monitoring’ by the WHO.
22
125
377
3
39
125
In de Europese vaccinatiecampagne worden die hoopgevende, op BA.4/5 gebaseerde, vaccins misschien wel gegeven, maar in de Nederlandse vaccinatiecampagne niet hoor!
15
40
120
Zo! Het
@rivm
heeft BQ.1.1, BQ.1 en XBB in hun kiemsurveillence tabel opgenomen. 🥳
Aan de hand hiervan is mijn inschatting dat BQ.1* in de loop van volgende week (43) dominant zal gaan worden.
1/3
2
49
119
Australia will be a nice one to keep an eye on, because they have the top 5 of fastest growing variants.
The last week is still prelimary. And numbers are still low, but that might change quickly.
Data from GISAID.
9
56
119
This shows very well how different BA.1 and BA.2 are, in my opinion.
From the Norwegian report (which I cannot read).
10
33
116
SARS-CoV-2 infections are rising passed the levels of last Christmas's JN.1 wave in NSW Australia
Mostly KP.3
But FLiRT plus S:S31del or F, not in this chart, were rising fast and around 10% in the most recent week covered on GISAID a week ago
And a single KP.3 plus a S:S31P!
Influenza levels are rapidly increasing. Now is the recommended time to get your influenza vaccine. COVID-19 and RSV are at high levels.
Full report:
More info:
41
34
50
3
35
118
A big new upload from Spain/Andalusia/Sevilla shows an even bigger share for KP.3 there, mostly because of a lot of KP.3.1.1, which has the extra S:S31del mutation.
Only samples from Monday and Tuesday (28/29th of May) for week 22 so far.
Portugal has experienced a large increase in Covid cases and hospitalizations recently, and the latest figures indicate that KP.3 (with S:Q493E) makes up about 67% of the most recent sequences, higher than in any other country. 1/2
13
192
456
7
45
117
Dit is niet eerder voorgekomen
Een nieuwe duidelijk snellere variant, die het overneemt op een moment dat de rioolwaarden (en dus waarschijnlijk het aantal infecties) nog duidelijk aan het stijgen zijn EN op een zeer hoge waarde zitten
Wat zal dit doen met de ziekenhuisopnames?
Ik gok dat wij in de loop van deze week (49), de grens van 50% JN.1+XDD passeren.
Let op! Week 46 is waarschijnlijk nog niet eens half compleet.
1/2
2
17
60
38
52
111
The BA.2 share keeps growing in Germany as well. Seems around 3% on the 8th of January.
Nice graph from
@LenaSchimmel
and
@CorneliusRoemer
👏
4
27
106
There were also 4 BA.2.86 (not .1) found in NSW/Australia (1 from week 37, 3 from week 38).
And the EG.5.1 growing seems partly due to its sublineage HK.3, which is one of several FLip lineages growing in NSW.
Together those accounted for 3% in week 35, but 38% in week 37/38!
COVID-19 weekly update – Friday 29 September 2023
In the 7 days to 4pm Thursday 28 September, there were:
• 2,232 new cases, 1,114 positive rapid antigen tests (RATs) and 1,118 positive PCR tests.
• 17 lives lost
25
48
66
4
31
109
After not uploading to
@GISAID
for a while, Gauteng (South Africa) uploaded some samples again.
It looks like BA.2 has become dominant there in week 2.
A bit soon to tell, but I will be keeping an eye on that red line (cases in Gauteng), to see if it's going to rise again.
6
34
106
I still dare say BA.2 has become the dominant variant in Denmark in the last couple of days!
(But I accidentally removed my last tweet about it 🙃).
Newest graphs based on
@GISAID
data here, based on 700+ samples on the 2nd of January)
7
44
106
The first XBB.1.16 has been found in China.
On the 7th of March in Guangdong.
2
29
103
Groot onderzoek in Scandinavië.
Beide bivalente vaccins bleken effectief in het beschermen tegen ernstige ziekte, maar de BA.4/5 versie gaf meer bescherming dan de BA.1 versie die we in Nederland kregen.
Fjerde stik med variantopdateret covid-19-vaccine beskyttede effektivt mod alvorlig sygdom.
Læs mere om det nye store studie fra Danmark, Norge, Finland og Sverige her 👇
151
20
107
9
52
104
De eerste XBB is gevonden in Nederland. In week 38 in Gelderland.
Verder zijn er nu 3 BA.2.3.20 gevonden. 1 in week 37 in Groningen en 2 in week 40 in Limburg en Utrecht.
De BQ.1.1 groeit het hardst.
BQ.1*= BQ.1+BQ.1.1+BQ.1.2+BQ.1.3
Voor week 40 zijn nu 8 uit 99 samples BQ.1*
8
30
102
JN.1 with extra S:R346T and S:F456L have been growing all over the world in many different sublineages.
Be aware that these graphs are based on a very small amount of samples and are incomplete for recent weeks.
NB
@xz_keg
is doing a marvelous job finding recombinants as well!
2nd generation JN.1s are on the way, with the combo of S:R346T+S:F456L. KP.1.1=JN.1+S:V1104L+S:F456L+S:K1086R+S:R346T KP.2=JN.1+S:V1104L+S:F456L+S:R346T
KR.1=JN.1.1+S:R346T+S:F456L
(More to be designated)
4
21
79
5
32
101
"Na één schooldag alweer klassen in quarantaine: “Overviel ons compleet”"
18
37
98
@MarionKoopmans
@blijfthopen
Je bevestigd mijn punt.
Ik heb helemaal niet gezegd dat elke individuele ziekte of sterfte voorkomen zou moeten worden, maar vaccinatie is een niet ingrijpende maatregel die de laatste keer, volgens de meeste cijfers (ook die van het
@rivm
), ongeveer 50% extra bescherming gaf!
5
5
100
'What is ‘stealth Omicron’? The rise of the subvariant is alarming some scientists who say it needs its own Greek letter'
Met mijn tweets. 😀
12
19
99
Dit begint echt surrealistisch te worden. Wil iemand me effe knijpen, zodat ik wakker wordt?
Of moeten er juist andere mensen geknepen worden?
20
32
100
#kiemsurveillence
#randomsurveillence
Hetzelfde beeld als in veel andere landen in de wereld. Een strijd tussen BA.4, BA.5 en BA.2.12.1, die de BA.5 lijkt te gaan winnen.
1/3
5
34
98
29% BA.2 in Amsterdam op 7 februari.
Zou die automatisering van het melden van positieven net op tijd komen? Zodat we zometeen snel kunnen zien hoe hard het aantal positieven weer stijgt als BA.2 dominant wordt?
Genoeg geboosterden over, die 3x zo vatbaar zijn voor BA.2 dan BA.1
A total of 55/77(71%) randomly selected SARS-CoV-2 positive samples, collected 7th Feb 2022 at
@GGDAmsterdam
testing facilities, were positive for a BA.1-like variant and 22/77(29%) for a BA.2-like. Thanks to
@amsterdamumc
&
@inBiome
.
1
13
34
9
41
99
As we see BQ.1(.1) rising and becoming substantial in Europe eg. and XBB to an even greater extend in Singapore and Bangladesh eg., BA.2.3.20 seems to have become dominant in the Phillipines.
About 30 samples per week from airport surveillence of South-Korea, Japan, Singapore.
3
32
98
#kiemsurveillence
(random)
De BA.5 groeit ook het hardst in Nederland! Voor de mensen die mij een beetje volgen, geen verrassing.
>>>
4
26
96
We hebben in Nederland inmiddels 2 SARS-CoV-2 dagrecords in het riool, maar nog net geen weekrecord. Maar dat kan nooit lang meer duren.
In het tweede figuur zie je het weekrecord. Dat was tijdens de BA.2 golf, begin maart 2022.
13
30
97
I have submitted an issue for the most peculiar variant I ever investigated.
It looks most like a BA.5.2.1, but it has the BA.4 N:P151S, BA.2/4 ORF:D61L (3 nuc muts), T15096C like Delta, T6979G like BF.1 plus 11 extra private mutations.
25 samples and only in Denmark for now.
3
28
95
In Israël zijn 2 BA.2.75's gevonden, in reizigers uit Frankrijk, die met sequencing gelinkt worden aan het Nederlandse sample.
@rivm
Weten jullie inmiddels al meer over de bron van het Nederlandse geval? Wellicht is deze informatie nog nuttig.
H/t
@shay_fleishon
@dirkeggink
>>>
5
23
97
Echt minimale verschillen tussen al die verschillende Omikronvarianten. Toch? Daarom is de BA.1 natuurlijk ook volledig van de kaart geveegd door BA.2* en BA.5*! 🤯
@ChapmanSysy
Hi Syreetha, we prikken sinds de 19e met vernieuwde vaccins tegen de BA.1-stam. De BA.4-5 volgen zeer binnenkort. Het OMT-V adviseert om geen onderscheid te maken tussen de vaccins tegen subvarianten van omikron. Toelichting: ^JM
19
7
8
8
29
90
Time for a new world update on BA.2.
A 🧵 this time. I always mention that the latter weeks are not complete and that this differs per country/region. I am including the regions this time, to show that.
Also, these samples are not solely collected randomly. So, be aware of bias
2
29
93
Maar even een draadje 🧵.
Ik heb de laatste tijd niet meer wekelijks de Nederlandse cijfers geplaatst met grafieken. Dat komt niet omdat ik de cijfers niet meer analyseer, maar omdat ik het steeds lastiger vind worden om zicht te hebben.
Hieronder wat voorbeelden daarvan.
1/13
7
29
91
7 samples in 4 countries already!
One in Denmark as well.
This EG.5.1.1(HK)/JN.1 recombinant has been designated and is called XDD.
It has a JN.1 Spike, but 2 parts of HK at the outer parts of its genome.
Only 4 samples for now, but all recent and from 3 different countries.
Let's see where it goes!
7
76
238
1
21
91
Ik geef BQ.1/BQ.1.1 in Nederland de grootste kans om binnenkort dominant te worden. Omdat ze heel hard groeien en al regelmatig gevonden zijn in Nederland. En daar lijkt de immuniteit na basis vaccinaties en BA.1 infectie dus minder goed tegen te beschermen dan immuniteit na BA.5
From the top 10 growing variants that were researched, only BN.1 evaded immunity after 3 CoronaVac + BA.1 infection a bit less than after BA.5 inf..
XBB, CA.1 and BA.2.3.20 evaded BA.1 immunity a bit better, but BQ.1 and BQ.1.1 evaded BA.1 immunity much better then BA.5 immun.!
2
8
29
6
28
89
Beste
@rivm
,
BA.2.86 is juist geen XBB!
(En het riool zou eigenlijk juist ideaal zijn om snel te v kunnen zien of JN.1 (BA.2.86.1.1) al dominant is in Nederland.)
3
23
92
Flinke slag om de arm, omdat we inmiddels op maar 52 samples voor week 21 zitten, maar XBB.1.16 lijkt wel flink te stijgen.
Nu ook de rioolwaarden niet meer dalen, zou het binnenkort wel weer eens kunnen gaan stijgen.
XBB.1.16 zal samen met XBB.2.3 de 50% al wel halen..
#KS
1/2
6
27
92
Hopefully this will demonstrate how crazy the battle between various variants/sublineages is right now. 😳
A selection even!
XBB is a BM.1.1.1/BJ.1 recombinant. BM.1.1.1 is a BA.2.75 sublineage and BJ.1 is BA.2.10.1.1.
BQ.1 = BA.5.3.1.1.1.1.1
Week 37 is preliminary!
4
28
90
Jawel hoor, alleen noemen jullie alles Delta. En moesten ze tot aan vandaag gevonden worden door naar 2 specifieke mutaties te zoeken, omdat de naam AY.4.2. nog aan de samples toegekend moest worden.
Bij deze dan de primeur (wat dus eigenlijk geen primeur is).
7
23
89
Hoe kunnen we zo in hemelsnaam weten wanneer er hier een nieuwe snellere variant dominant wordt, met bijbehorend golf?
Wel 'Oh Oh China' en mensen terugroepen van reces, maar zelf, na bijna 3 jaar, nog niet eens een goede tabel maken met gegevens die al wel verzameld zijn!
2
15
90
Nou, dat was snel 🙃.
Het RIVM heeft net 1k samples geüpload waaronder 1 BA.2.75. Uit Gelderland, test afgenomen op 26 juni.
Thanks,
@RajlabN
, for letting me know!
5
26
87
CH.1.1* has the highest percentage of those. That makes sense, since it's very common in the UK.
But it doesn't seem to grow as fast as DeltaOmicron recombinant descendant XBC.1, which was very common in the Philippines and which is common and growing in Western Australia
2/6
4
25
87
@mvankerkhove
@dmaccannell
@WHO
Let's look at Denmark.
They went from around 2k sequenced samples per week (at a low point) before Omicron to less then 50 per week in the last few months.
That means a new variant is seen first at 2% instead of at 0,05%.
That's 5 weeks later if the variant doubles per week!
3
18
88
The US is joining the rest of the world in having significant and rising amounts of JN.1 + S:R346T + S: F456L.
Attention, the more recent the weeks are, the more incomplete the data is. I have cut off the last 2, because of that.
Since we just started week 15, I think these graphs could be telling us that in several countries in the world JN.1 plus S:R346T and S:F456T (
#FLiRT
) has reached or will soon reach 50%.
Therefore spring waves might be starting.
Be aware! Data of recent weeks is often incomplete
8
46
132
3
26
87
We zijn Omicron zelfs al aan het exporteren...
8
24
85
In Australia KP.3 seems to have already passed JN.1 plus FLiRT and might even be dominant at this moment.
Since several sequences miss coverage near amino acid 450 of the Spike, I used very simple queries. S:R346T in early weeks therefore include HK.3 etc. besides JN.1*.
I am not as sure about FLiRT becoming the dominant one, as I was before
The competion is growing, especially KP.3 (F456L+Q493E, no R346T), which is not surprising seeing that
@yunlong_cao
found it most immune evasive and
@BenjMurrell
found it to have the biggest growth advantage
7
43
140
1
36
83
21% BA.2 in de laatste steekproef in Amsterdam!
Samples afgenomen op 31 januari.
Heel fijn dat ze er daar nog op screenen, waardoor we snel de resultaten kunnen zien.
In de steekproeven van vorige week zaten ze nog op 3-4% BA.2.
A total of 76/96(79%) randomly selected SARS-CoV-2 positive samples, collected 31st Jan 2022 at
@GGDAmsterdam
testing facilities, were positive for a BA.1-like variant and 20/96(21%) for a BA.2-like. Thanks to
@amsterdamumc
&
@inBiome
. We will continue to monitor BA.2 closely...
6
23
65
3
33
83
@GGDGHORNL
@BOinK_info
We gaan weer voor een flinke verspreiding via de kinderdagverblijven, zie ik. Met keelpijn, neusverkoudheid of reuk/smaakverlies hoeven ze niet eens een zelftest te doen? Lekker voor de zwangere vrouwen die daar komen!
4
30
86
CovSpectrum query to follow 4 major variants in the world
Purple=CH.1.1
Orange=XBB.1.5
Red=XBB.1.9
Green=XBB.1.16
Just enter a country on top and/or click "show regions"
Click "Log scale" to be able to compare growth
Click "Show CI" for reliability
2
32
83