Fumiaki Ito
@FumiakiIto110
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Joint postdoc @UCLA @zhou_lab and @USC | Structural Biology of HIV and APOBEC | Cryo-EM
Los Angeles
Joined December 2010
RT @HuiWang007: Excited to share our latest work: Using cryoET, we unraveled the in situ structure of a methanogen surface layer and its ce…
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RT @ShihengLiu: Thrilled to share our latest work: native cryo-EM structure of the Dystrophin-Glycoprotein Complex (DGC) is now published i…
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RT @naturemethods: Introducing spIsoNet, a software tool that addresses the challenges of map anisotropy and particle misalignment in cryo-…
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Check out our latest study on the DNA polymerase theta (Polθ), a precision oncology target for HDR-deficient cancers. Our work uncovers the inhibitory mechanism of a potent Polθ inhibitor using cryoEM, accelerating rational drug development strategies:
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RT @biorxivpreprint: Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining #b…
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Check out our new preprint work on mechanistic insights into the action of DNA polymerase theta: Through six cryo-EM structures, we show step-wise DNA engagement by helicase domain of pol theta. A leap towards targeting HR-deficient cancers!
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RT @CorneliusGati: I am delighted to announce that we are hosting the 9th SoCal CryoEM Symposium, Oct 11th 2024 @USC @USCBridge in LA. We a…
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RT @RemiBuisson: Now online! APOBEC3A and APOBEC3B drive distinct mutational landscapes in tumors. We showed how A3A and A3B substrate pref…
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RT @biorxivpreprint: Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain
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Check out our latest preprint work on SARS-CoV-2 Nsp15: We present cryo-EM structures of SARS-CoV-2 Nsp15 bound to its physiological substrate polyU containing RNA, illuminating the basis for immune evasion tactics by coronaviruses!
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RT @HuiWang007: Our paper is out! We resolved the sheath structure from M. Hungatei cells using cryoET. Thanks to all the coauthors @zhou…
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RT @CorneliusGati: Please share far and wide: My lab has an opening for a postdoctoral researcher, to study the structural biology of membr…
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@CorneliusGati @CellCellPress Congratulations to the entire team! I agree that our Glacios/falcon-4 is far more than screening microscope
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Check out our latest paper on HIV Vif-APOBEC3H complex structure by cryo-EM: This has been a collaborative project between @zhou_lab and Xiaojiang Chen lab at USC.
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RT @zhou_lab: Check out our cryoEM result of mRNA editosome in Trypanosoma brucei! Awesome collaboration with Aphasizhev lab from Boston U.…
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RT @HiCryoEM: Our latest article on the role of RNA bridging APOBEC3G-Vif is out in @NatureComms Full text PDF her…
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RT @gonenlab: Dr Anna Shiriaeva completed her doctoral studies atvthe Cherezov lab studying GPCRs. Her focus was the vasopressin V1B recept…
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