The Zhou Lab
@zhou_lab
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We are the Zhou Lab @UCLA. We use #cryoEM and #cryoET to study viruses, viral proteins, protein assemblies, and membrane proteins. Student-curated account.
University of California, Los
Joined May 2019
We're so proud to be featured on the cover of @nature! Brilliant work from Dr. Peng Ge and team, uncovering intricacies of the fascinating P. aeruginosa bacteriocin at high resolution using #cryoEM.
This week on the Nature cover: Molecular syringe. High-resolution structures shed light on the workings of an antibacterial nanomachine. Browse the issue here:
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RT @HuiWang007: Excited to share our latest work: Using cryoET, we unraveled the in situ structure of a methanogen surface layer and its ce…
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Please check out our just published Nature paper "Native DGC structure rationalizes muscular dystrophy-causing mutations", the excellent teamwork from @ShihengLiu @ tiantiansu and @xianxia13
Thrilled to share our latest work: native cryo-EM structure of the Dystrophin-Glycoprotein Complex (DGC) is now published in Nature! This discovery sheds new light on the molecular basis of muscular dystrophies and pave the way to novel therapies.
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RT @ScienceMick: Excited to share our new work! We shed light on the sociology of virus-induced condensates supporting reovirus assembly a…
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Proud to see the spIsoNet is online now! Hope you enjoy using it!
Introducing spIsoNet, a software tool that addresses the challenges of map anisotropy and particle misalignment in cryo-EM caused by the preferred orientation problem. @zhou_lab @yuntaoinnit @hongcheng_fan
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RT @mimi1inh: We have a fully-funded postdoc position in the @cmholab in #NYC to study how #membraneproteins drive host-pathogen interactio…
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RT @HuiWang007: TomoNet is now published in Biological Imaging! It is a 100% GUI-based cryoET integration pipeline package. Specifically, w…
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@Jiaxing_Tan_ Thanks for trying it out! Dr. Liu regularly check the issues/questions in Google group, he should reply your question in the next few days.
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Beautiful work from Xian @xianxia13 and our amazing collaborators!
Excited to share our latest work in @CellCellPress on how bluetongue virus packages its RNA & assembles its capsid inside host cells! Using #cryoET & #cryoEM, we've visualized this process with 11 structures. Great collab w @gonenlab @zhou_lab 🦠🔬
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RT @FumiakiIto110: Check out our latest preprint work on SARS-CoV-2 Nsp15: We present cryo-EM structures of SARS-C…
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RT @HuiWang007: Our paper is out! We resolved the sheath structure from M. Hungatei cells using cryoET. Thanks to all the coauthors @zhou…
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Congrats!
Check out our latest paper on HIV Vif-APOBEC3H complex structure by cryo-EM: This has been a collaborative project between @zhou_lab and Xiaojiang Chen lab at USC.
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Check out the recent cryoET work with our beloved colleagues in Hill lab on the flagella structure of T. Brucei.
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Check out our cryoEM result of mRNA editosome in Trypanosoma brucei! Awesome collaboration with Aphasizhev lab from Boston U. Many congrats to Bruce @ShihengLiu and other coauthors for another wonderful piece of work!
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Congrats to Jason, Jane and Yuntao @yuntaoinnit
The group of Hong Zhou @MicrobioUcla & their collaborators determined the cryo-EM structure of filamentous 3-methylcrotonyl-CoA carboxylase from Leishmania tarentolae and discuss its mechanism @zhou_lab
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RT @FumiakiIto110: Long-lasting enigma in HIV study: how HIV antagonizes the host antiviral systems and evades the immunity? We are addres…
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RT @NatureComms: Atomic model of vesicular stomatitis virus and mechanism of assembly @zhou_lab
#virology #CryoEM #structures
https://t.…
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Isonet paper is published online now on nature communications! Congrats to Yuntao @yuntaoinnit and Heng!
Isotropic reconstruction for electron tomography with deep learning #MachineLearning #NatureJournal #AI
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