Edda Schulz
@EddaGSchulz
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Systems Biology, Epigenetics, X-chromosome inactivation Lise-Meitner Research Group Leader @MPI_MolGen in Berlin, @eddaschulz.bsky.social
Berlin, Deutschland
Joined August 2017
📢 New preprint from the lab! CRISPR-screening wizard 🧙 🧬 @TSchwammle figured out how different signals 🚦 are integrated at the Xist locus. See his tweetorial below.
How do cis-regulatory landscapes integrate information from many transcription factors (TFs)? Using CRISPR screens we map TF-RE wiring at the Xist locus and uncover two regulatory axes, driving basal activation & high transcript levels.
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RT @YildirimLabDuke: @LabSchirmer, @PlathLab @The_Lei_Team, Giacomo Cavalli lab @CNRS, @EddaGSchulz, @deWitlab, @MJordanRowley, @LabNamekaw…
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Together with PhD student @AlexandraMMar we wrote a News&Views @NatureGenet about the new paper📜 from @xielablife. A stunning data set on the 3D chromatin structure of the X chromosome in early embryos reveals unexpected large-scale structures: 🐭🧬🔺🔺
One of the X chromosomes in females is silenced with a microscopically distinct chromatin configuration. Happy to share our latest work on deciphering how the X chromosome folds during its inactivation for the first time in mouse female embryos!
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RT @bulutkarslioglu: Our new work is out today! Long time in the oven, this has been a really fun and informative collaboration led by Dhan…
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RT @amjeve: X-chromosome inactivation (XCI) A subject collection from @Dev_journal marking 60 years since Mary Lyon proposed the theory of…
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RT @rafaelgalupa: Don't miss Daniela Cecalev @cecalev's review on "Compensation of gene dosage on the mammalian X" together with Beatriz Vi…
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RT @maxplanckpress: Ready to lead your own research team-?😎The Max Planck Society offers you the chance to head an independent Research Gro…
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RT @lisamar2017: if you are passionate about the therapeutics of the future and want to be part of the 'RNA revolution' apply for this proj…
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@mpi_ie @maxplanckpress @Iovino_Lab @AsifaAkhtar1 @hilgers_lab @JumanaAHA @a_denboba @ValeFlury @GrosschedlL @guha_sukanya @CIBSS_UniFR @Nina_CabezasW That's great news! Congratulations, Nicola!
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Congratulations, Valerie!!
New job, starting next summer! Extremely excited to join the extraordinary scientific environment at @UniBasel and the @DepBiomedicine.
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RT @GontanCristina: 📢 WE ARE HIRING! We offer a position as Research Technician in Stem Cell Biology to work in sex differences in neurodev…
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RT @GallowayLabMIT: on unimodal setpoints and how to get them from synthetic promoters... tweetorial coming soon... or see you next Thur…
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It was a pleasure to write this review together with @nellykanata and Rachel Duffie @sneexish from the Lomvardas lab on the principles that govern monoallelic expression of olfactory receptors and Xist for @Dev_journal
Establishment and maintenance of random monoallelic expression In this Review, @nellykanata, @sneexish & @EddaGSchulz @MPI_MolGen give an overview of the regulatory mechanisms and current models for establishment and maintenance of monoallelic expression:
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