Plath Lab
@PlathLab
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Twitter feed for the laboratory of Prof. Kathrin Plath @UCLA
Los Angeles, CA
Joined June 2019
📢 Ready to rethink XIST? Our latest work, now in Cell, challenges two fundamental assumptions about XIST: its cis-limited action, and its role in equalizing gene expression between XX and XY genotypes. Dive in 👇🤿(1/6)
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@SridharanLab @ISSCR @ChronisLab @RitchieHoLab @vincentpasque was fun seeing you all! Great meeting!
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RT @VashKurdistani: Excited to share our latest work: L126 fine-tunes enzymatic activity of histone H3, a discovery made possible by viewin…
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RT @andrea_cerase_: I'm delighted to have been mentioned in the celebratory article commemorating the 30th anniversary of NSMB #Xist_granul…
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RT @FrancoLabUCLA: Can you sense RNA with other RNA? Our characterization of #fluorogenic #aptamer #sensors in vitro is finally published…
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One of the most extensively studied lncRNAs continues to surprise us! A huge thanks to everyone who helped with this! @Iris_Dror @tsotnech @ClaraCanCanoe @Dr_Sahakyan @YolandaMarkaki @ChronisLab @Mandy_Collier @WeixianDeng @DingFangyuan, #lncRNA, #SexDifferences (6/6)
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In female naïve human pluripotent stem cells (PSCs), XIST is dispersed in the nucleus and X-chromosome dampening (XCD) occurs, raising the question of whether XIST mediates XCD. Knocking out XIST, we found that it is required for XCD in naïve hPSCs. (2/6)
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📢 Ready to rethink XIST? Our latest work, now in Cell, challenges two fundamental assumptions about XIST: its cis-limited action, and its role in equalizing gene expression between XX and XY genotypes. Dive in 👇🤿(1/6)
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In collaboration with @dinodicarlo, we used hydrogel nanovials to capture and measure the secretion of VEGF-A alongside mRNA transcriptomes. Surprisingly, we found that the VEGFA transcript was not the best predictor of secretion! 2/2
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Congratulations to Plath lab member @JustinLangerman who was awarded the UCLA 2023 Boyer/Parvin Postdoctoral Award. 🎉
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RT @JonesLabUCSF: Join us for this incredible @GordonConf on #StemCells and #Cancer in beautiful #Tuscany organized with @CedricBlanpain an…
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RT @NovitchLab: I’m happy to share our new paper with @LabMomoko published today which examines how differences in…
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Congratulations to @YolandaMarkaki and all other award winners for the UCLA 2022 Boyer/Parvin Postdoctoral Award. Tune in for her seminar on "How to silence a chromosome" July 20th at 12PM PT. 🧬
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RT @TTdevbio: It’s finally out! Many thanks to my colleagues @jacksongcheng and my mentor Andy McMahon at USC for making this happen. #orga…
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