FASTGA uses very efficient and flexible file format/library we are now using for multiple purposes. Compressed, indexed, schema-containing binary files with record-based text equivalent. Single C file interface with no dependencies.

Gene Myers just released super fast whole genome aligner He and @c1zhou and I have lots of ideas for downstream use.

Looking for genome assembly innovator to tackle hard problems arising in sequencing 1000s of species. #DarwinTreeOfLife

RT @Cichlid2022: 📢 Extension for abstract submissions! We are extending the deadline to Friday 22nd July - please share! We look forward…

RT @ilianaBista: Very excited to share our new paper on genome evolution of the amazing Antarctic notothenioid fish radiation, with insight…

@ewanbirney I have been using it for notes in talks/seminars since xmas. Lovely writing experience, backed up, and no email/web distraction. I collect series of talks into a single document to avoid lots of tiny files.

RT @erga_biodiv: This Sunday the world celebrated the #InternationalDayforBiodiversity. Listen as some ERGA members share their thoughts on…

RT @darwintreelife: On this @UN International Day for Biological Diversity, we're proud to be doing our bit in the field of #genomics to he…

@gunesaynasinda @DavidKoslicki @krsahlin @pashadag @ctitusbrown @RayanChikhi @shenwei356 @luizirber Well that is just with your construction. But any deterministic function that delivers a subset of the hashes will do, e.g. those divisible by h. The min is not essential to this in the sense it is in a minimizer. And Edgar's syncmer is a k-mer whose terminal s-mer is minimal.

@krsahlin @pashadag @ctitusbrown @gunesaynasinda @DavidKoslicki @RayanChikhi @shenwei356 @luizirber Or perhaps if you are hashing then modhash, minhash, frachash (frac-hash?), synchash...

Congrats @nygenome and all involved. Great to see 1000 Genomes data resource brought up to date.

RT @SangerToL: VACANCY: If you're an experienced leader with a background in project management for large-scale research programme, come jo…

@jcbarret Great job. Item 2, rate of increase in large N context, is the clincher for me: p(observed relative growth|number of parallel infections) is vanishingly small under random drift. Is viral titre higher in people infected with this strain?

PathPhynder for efficiently placing ancient DNA data into reference phylogenies, e.g. Y or MT, plus a new integrated Y chromosome data set on ~120k sites. Congratulations @ruidlpm

@arambaut @nbierne @firefoxx66 Also, are you now sequencing virus genomes intensively from long term/chronic covid patients, especially before and after convalescent plasma treatment?

@arambaut @nbierne @firefoxx66 In that case, especially under the hypothesis this is in response to selection to evade neutralisation by convalescent plasma, isn't that a concern about the capacity of this strain to avoid immunity from prior infection or vaccine?

RT @khmiga: What amazing work @GershmanAriel! The Human Satellites have such interesting genome biology and regulation. We are now gaining…

Thank you @aphillippy and @khmiga and the whole T2T team. This is an absolute triumph, the culmination of 30 years of human genome sequencing. Great to see the future of genomics - makes me so happy.

Join the call for the EU to strategically fund a #EuropeanReferenceGenomeAtlas as part of @EBPgenome. Sign here: Reference genomes for all life will underpin our future interactions with the living world.