A Danish cohort study indicates individuals with #Headache disorders face a higher risk of #Suicide. The study highlights the need for early evaluation and targeted behavioral health interventions. @jamaneuro

#New insights into JAK enzymes reveal their competitive binding to cells, paving the way for novel therapies targeting autoimmune disorders and immunodeficiencies. This could transform future treatment strategies. @scisignal

A detailed immune map of #PancreaticCancer reveals potential for precision treatments, highlighting macrophage-based therapies as a promising avenue for targeting specific tumor environments. @NatureComms

#Mitochondria in the hippocampal CA2 region play a crucial role in #SynapticPlasticity, impacting learning and memory. This insight could inform therapies for #NeurologicalDisorders like Alzheimer's. @SciReports

#Excessive #ScreenTime in toddlers is linked to lower language development, while book exposure and shared screen time with adults enhance #LanguageSkills. Pediatric guidelines recommend limited screen use. @PLOSONE

A key enzyme, GUK1, has been identified as a metabolic driver in #LungCancer, particularly in ALK-positive cases. Targeting GUK1 could pave the way for novel #Cancer therapies. @harvardmed @CellCellPress

#Brain scans of infants show that early #BrainActivity in response to smiling faces may predict social behavior in toddlerhood, highlighting the role of the #MedialPrefrontalCortex in social development. @uva

#Oxytocin-secreting neurons are disproportionately disrupted in a mouse model of #Autism. Stimulating these neurons restored social behaviors, suggesting potential therapeutic strategies for autism. @riken_en @NatureComms

#Neural oscillations are crucial for #Brain information processing, enhancing #Network performance and offering insights for energy-efficient AI development, according to recent findings in neurobiology. @PNASNews

#Researchers identify brain mechanisms in mice that suppress instinctive #Fear, potentially paving the way for new treatments for phobias, anxiety, and PTSD by targeting specific neural pathways. @swc_neuro @sciencemagazine

#A recent intervention reduced unnecessary preoperative tests from 37% to 14% in low-risk surgeries, maintaining patient safety and optimizing resource use. This model is now being tested statewide. #HealthcareEfficiency @umich @JAMASurgery

A short form of IL-18, produced by ##TumorCells, activates natural killer cells, enhancing their anti-tumor function. This finding could lead to new #CancerImmunotherapy strategies. @natimmunol

#Granzyme K (GZMK) activates the complement system, driving #Tissue damage in autoimmune diseases. Targeting GZMK could lead to therapies that inhibit this harmful pathway while preserving immune function. @MassGenBrigham @nature

#Electrical spinal cord stimulation shows promise in restoring neural function in spinal #Muscle atrophy. A pilot trial reports improved motor function and reduced fatigue in participants after one month. @NatureMedicine

New research identifies two #Ocd subtypes with distinct #GrayMatter patterns and disease epicenters, offering potential for personalized treatment strategies based on neuroanatomical differences.

#CBD use during pregnancy may pose risks, including impaired #FetalGrowth and behavioral changes in offspring. New findings highlight the need for caution and further research on #Cannabis consumption during pregnancy. @mcmastereng

#GutMicrobes may influence #Anxiety through microbial metabolites like indoles, suggesting potential probiotic therapies. This gut-brain connection could revolutionize #MentalHealth treatments. @dukenus

Scientists identify fibroblasts as key contributors to #PulmonaryFibrosis, with Runx2 as a critical factor in their harmful transformation. Targeting Runx2 may offer new therapeutic avenues. @ColumbiaMed @nature

#Schizophrenia cases linked to #CannabisUseDisorder in Ontario have risen from 4% to 10% post-#Legalization. The increase highlights the need for targeted prevention strategies, especially for youth. @ICESOntario @jamanetworkopen

#Meditation alters activity in the amygdala and hippocampus, key areas for memory and emotional regulation, as shown by intracranial EEG. This insight could enhance meditation-based mental health interventions. @mountsinainyc @PNASNews