Holly Ingraham
@hollyingrahamSF
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Discovery Sciences at #UCSF | Neurocircuits in the Brain and Gut | Hormone Signaling | Female Physiolgy and Women’s Health
San Francisco, CA
Joined March 2018
A thread acknowledging the many contributions of the @UCSF @UCDavisHealth team for our study, out online at 1/7—We identify a new hormone, CCN3, produced in the hypothalamus to build bones and offset bone loss during lactation - a 5-year journey. One
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Wow amazing that my best friend in life @DJuliusSF ❤️ and colleague @ardemp got the early phone call 📞 this morning for the #nobelprize2021
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Hey scientists - @UCSF is hiring - remember you don’t need a CSN paper or a K. We are looking for fresh ideas, curiosity, and desire to work in a public university with an awesome academic research community. Pls RT 👇
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A memorable night in Stockholm with @DJuliusSF, PAJ and so many others @NobelPrize banquet
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Reality ✔️. Discovered this week while chairing NIH panel that 50% of panel had no idea what @biorxivpreprint is. Others were skeptical. @cziscience @mbeisen @pollyp1 @superkash and others - We need to work on this. Any ideas?.
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Normalized post #nobelprize2021 for @DJuliusSF? .Definitely!!.🌺 for 25 yr anniversary today.🧺 attending to this weekly event
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Scientists Discover a New Hormone that Can Build Strong Bones | UC San Francisco . Thank you @LauraKurtzman for a great summary of team effort with @dr_ambrosi
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The golden @NobelPrize handshake 🤝 at lunch today with @DJuliusSF Randy Schekman and Richard Axel. And yes this cake was well worth all those calories!
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Other than Salk, perhaps the most beautifully designed research institute here @NCBS_Bangalore - dedicated to outstanding basic science in India 🇮🇳. Thanks for the opportunity to present our work.
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Honored to be up there with others @theNASciences #NAS159 meeting with family and friends (and wild hair!).
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SCIENCE RECOGNIZED! Watching @DJuliusSF credit his🏫 physics #teacher as he chats with @WhiteHouse Scientific Advisor @EricLander46 from the @WHOSTP after receiving #Nobelprize2021. "We know that education is the key to unlocking human potential” @FLOUTUS
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Danica Fujimori @FujimoriLab, our colleague and advocate for #WomenInSTEM ♀ announced as the 2020 Bowes Biomedical Investigator @UCSF. 👏🏽👏👏🏿
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Happy to announce that the Women in Basic Sciences at UCSF advocated, organized, and used data to have our awesome colleague Dr. Carol Gross recognized as the 2019 Faculty Research Lecture Awardee - our highest scientific honor at UCSF. @ucsf @wilsucsf #WomenInSTEM
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For those of you #postdocs interviewing for faculty positions, please be gracious to faculty who are spending their precious time to host you even if you have no intentions of taking the job. Paths will always cross at some point.
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Thank you 🙏🏼 Bill Krause and all of our fantastic colleagues for bringing this study to completion during the pandemic. @tollkuhn .@Profa_Correa .@xinduan.@NadavAhituv.
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Our neighbours provided the 🌶tie. Admitting that I was sound asleep 💤 when this aired - but headed to So Cal soon to see @DJuliusSF and @ardemp get @NobelPrize!!!.
Watching DJ giving his Nobel lecture wearing a pepper tie! 🌶🌶🌶
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The best note of congrats for election to @americanacad from my non-academic, non-science parents - noting my efforts to “open up the Science World 🌍 to many others”.
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Good bye 🇮🇳 .Last stop with @DJuliusSF.The Taj is truly STUNNING and Akbar’s tomb was also beautiful - so much history.
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Shout out to Sophie @DumontLab - who just received the 2018 Junior Award for Excellence in Research @ASCBiology and also the 2018 Outstanding Mentorship Award @UCSF. Thrilled to have Sophie as a colleague! #WomenInSTEM
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A hunt, a surprise, and then clarity - Congrats to the team! Love 😍 it. Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females
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Latest team effort to understand the cellular origins of #IBS and the sex-bias in women 🚺 with @DJuliusSF, @md_jrb and Brierley lab @Flinders. Gut Enterochromaffin Cells are Critical Drivers of Visceral Pain and Anxiety
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Headed to Bilbao now to find these two science geeks @DJuliusSF from @UCSF and @ardemp and celebrate discoveries in basic science.
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Capturing decades of tradition for @NobelPrize week with @DJuliusSF. These gentlemen work tirelessly in the 🥶 to snag autographs of every single laureate. Triple duty this year (2020-2021-2022)
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Truly honored - Awarded since 1977 by @TheEndoSociety for basic science & shared by scientific heroes | Wylie Vale (d) @salkinstitute | Pat Donahoe @MassGeneralNews | Al Gilman (d) @UTSW . Endocrine Society 2023 Laureate Recipients
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Passion and persistence in life ▶️ @brkthroughprize. Celebrating with @DJuliusSF @UCSF @UCSFPhysiology this morning.
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Wonderful to see that Women @UCSF and @GladstoneInst are finally taking a leadership role with the new appointment of Melanie Ott, MD, PhD @TheOttLab to lead the Gladstone Institute of Virology.
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Highlight for @DJuliusSF from @ucsf today - inspiring the next generation of scientists and world citizens by the @NobelPrize
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Truly honored. Thank you @FASEBorg for your sustained commitment over 3⃣0⃣ years to recognize #womeninscience - @TheEndoSociety, @APSPhysiology and @ASBMR.
🎉Congrats to the 2024 Excellence in Science Awards recipients: Holly Ingraham @UCSF, Pilar Alcaide @TuftsMedSchool, Mariana Byndloss @VUMCDiscoveries. The awards honor women scientists' excellence, leadership, and mentorship in their research fields.
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Introducing some of the amazing research being done by women @UCSF engaged in discovery/basic science. #WomenInSTEM
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My reflections.to younger trainees after 22 years in a male dominated enterprise. #womeninSTEM, #STEMdiveristy, and #WomendoingScience.
Be still my heart: @hollyingrahamSF now uses some of her keynote time to discuss issues in STEM for trainees, including underrepresentation of women in STEM and the nuclear receptor field. Powerful statements and some tips:
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“I’m not surprised” that women’s immune systems may do things in ways that men could learn from, Pinkerton said. For years, immunologists only studied males” @OSSDtweets
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Please note - I am grateful for the peer-review process, which prompted us to improve, refine, and expand our original posted preprint. Please take a moment to read the cordial and constructive points raised in the TPR (transparent peer review) file!.
Nature research paper: A maternal brain hormone that builds bone
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💰💰arriving soon @UCSF for @hollyingrahamSF lab after writing 8️⃣ grants this year. Contact me if you want to explore:.① How the female mind decides to use/store energy,.or.② Why females experience more visceral pain #IrritableBowelSyndrome #IBS.
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Great choice to appoint @OphirKlein permanent Director for Institute of Human Genetics (IHG) @ucsf. Klein’s group has done amazing working in development and regeneration.
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A powerful @nytimes image today of someone’s son, husband, father, or brother. Personal for me as my own son has Ukrainian roots, was born in Russia, and would no doubt be forced to fight and die for the lunatic in Moscow.
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What are the small things that irritate you as #WomenInSTEM - for me a recent request for $$$ from @UCBerkeley that relies on 1950 demographics. 🤦♀️🤦♀️
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Please @UCSF and @UCBerkeley ask yourselves why two top CA public institutions can’t diversify leadership in #neurohub etc. - do we need a law mandating change by @CAgovernor? We can do much better.
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As scientists, @DJuliusSF and I are smiling today Nov 7 2020 - facts are coming back to the USA after 4 long years.
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Last event of #nobelweek - dinner at Swedish Royal palace with one very long tablecloth, @DJuliusSF with cigar (not a fan) @perlmannlab and Prof Anna Wedell
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For you 🛋potatoes that might want more drive to #exercise - check out our new preprint done with the @nadavahituv @Profa_Correa @tollkuhn labs.
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Sharing our evolving thinking on Sex-Biased Diseases in Metabolism and Immunity. A beautiful study in collaboration with @gokcumen and @ethanjweiss .Brought to you by @joni_nikkanen (Presenting this at @OSSDtweets 2022) .
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Posing with a young Indian 🇮🇳 woman at Agra Fort built by Akbar
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Curious about #IBS and gut pain that degrades QoL, especially in women? Read our research briefing with S. Brierley @Visceral_Pain. Dialogue between specialized gut cells and nerves contributes to sex bias of gut pain
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Very cool study by two @UCSF colleagues - Androgen regulates SARS-CoV-2 receptor levels and is associated with severe COVID-19 symptoms in men
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Listening early this morning to Norwegian Academy of Science announcing the 2020 @KavliPrize @DJuliusSF and @ardemp
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Thanks Christina for the shout out.
What a treat to celebrate trailblazer @hollyingrahamSF yesterday as she received the 2023 @UCSF Lifetime Achievement in Mentoring Award!!! So well-deserved! 👏🏼👏🏼👏🏼. @CatherineRLucey @LowensteinMD @EVCProvost @TalmadgeKing .@MullinsLab
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A team effort by @moolakaari, @md_jrb and others @UCSF as well as the “down-under” gut gang @Visceral_Pain.
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Thank you for reiterating your policy on @biorxivpreprint and other #preprints - now can we get some meaningful education for panel members as not all of them are tuned into Tweeting.
In 2017, NIH announced (NOT-OD-17-050) that preprints and other interim research products can be cited in NIH grant applications. Common in other scientific fields, but relatively new in biomedical science.
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An amazing turnout for 2022 #HypoGRC power hour. Kudos to the all organisers for the highest turnout ever @GordonConf with 117 energetic participants -
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Two of my favorite @GairdnerAwards recipients celebrating @UCSF Ron Vale @ibiology and @DJuliusSF
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Here I am with @Shruti__apte from @TIFRScience. Congrats 🥳 and good luck on your scientific journey @Duke
Our congratulations to the 8 finalists of the 2024 Inspiring Science Award and the overall winner Abhinav Banerjee from IISc Bengaluru!. #2024InspiringScienceAward
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We could use some institutional muscle 💪 from @NIH and @HHMI and others to convince holdout 🙉 PIs that posting on @biorxivpreprint is essential for trainees. I keep hearing about PIs that continue to be skeptical. It is our job to convince them otherwise.
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A class of secreted mammalian peptides with potential to expand cell-cell communication | Nature Communications
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New faculty job in @UCSFPhysiology - Please apply #WomeninSTEM, #WomeninScience ♀︎♀︎♀︎ - Any research program in Cellular and Integrative Physiology considered, Deadline Dec 1.
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Leaving Bengaluru to Mumbai with @DJuliusSF, Mariam Ram (wearing one of her exquisite saris) and @emiliemarcus - No Contest BEST AIRPORT I have 🧳 through. FYI - every 🥻 is 6 yards which is why her suitcase is way bigger than mine. @TNQTechnologies
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Hey for the cool, minty scientists associated with the 2021 @NobelPrize and @UCSF - it's not all about the hot stuff - @davemc1968
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Getting to know the science (and 🥘) of @NeuroAlc in Alicante ES this week. Hosted by @neuroviana, Carlos B, S. Jurado Sanchez and others. Gracias 🙏 from us (@DJuliusSF)
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Why is @MarkusDellingSF @UCSFPhysiology so happy 😀- first R01 funded for innovative studies on cilia.
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TODAY Friday - A lecture and life story told by an exceptional scientist and leader who has inspired so many @UCSF, @UCSF_BioE, @Ucsf_Biochem and @ASMicrobiology.
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Sharing some morning joy from this Bagel 🥯 Birthday Creation made by @DJuliusSF. My son is smiling.
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Mark you calendars - the very FIRST Women in Discovery Science Lecture @UCSF given by @CWolberger from @hopkinsmedicine on #Histones and Ubiquitination 🧬. Thursday Jan 30th, 3:30 GH with Reception to Follow.
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At the @americanacad watching @Sifill_LDF sign after telling us to do more for all.👏🏻👏🏻👏🏼👏🏽 Standing ovation.
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Now it is real for @DJuliusSF Discussion thread on @Nextdoor in sleepy @WalnutCreekGov about @NobelPrize. Wonderful to know that the public appreciates what we scientists👩🔬do @UCSF. #EastBay proud!
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An amazing night celebrating 25 years of curiosity driven research for @DJuliusSF @brkthroughprize listening to Rachel Zhang (TS of China), @LennyKravitz and @iamwill.
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Publish houses of brick, not mansions of straw | Nature
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Me @brkthroughprize last night next to my all time favorite powerful #Woman J. Napolitano. Thank you for your service supporting public education @UofCalifornia and @UCSF
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Super excited to announce that @DrEmilyGoldberg will be joining @UCSFPhysiology and our neighborhood 🌁@UCSF to unravel secrets of aging and metabolism.
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Thanks for a full day of awesome science @UCDavisHealth. We definitely need to replicate this event @UCSF.
@LaSalleLabUCD @UCD_MMI @UCD_CBHA @MCIPUCD @BethanyCummings @hollyingrahamSF We also enjoyed time socializing and networking at the Great Bear Winery and distributing the awards to our trainees for Best Talks and Best Poster presentations. A great exclamation point to end the Basic Science Symposium Celebrating Women’s History Month 🎉
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Congrats to @DanielJDrucker - this weekend walking to sign in as newly inducted member of @theNASciences for his work on gut hormones @UofT
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Smiling with @DrEmilyGoldberg @UCSF and @AreyLab at @BCMHouston - two rising stars who just received the #NIHHighRisk DP5 Early Independence Award.
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Check out our new paper @NatureComms describing a brain-to-bone connection to increase bone density for #WomensHealth @SWHR. Led by C. Herber, a Young Investigator @ASBMR Awardee .
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Exceptional!. Quoting D. Julius (closed his X account) . “You’ve been an inspiration to so many of us (young and old) over the years, not only as an amazing scientist, but also as a first-class colleague, human being, and friend”. @JohnsHopkins.
Meet Jeremy Nathans, the 2024 World Laureates Association Prize (#WLAPrize) laureate in Life Science or Medicine. As a professor of molecular biology and genetics, neuroscience, and ophthalmology at the @JohnsHopkins School of Medicine, he has made groundbreaking contributions
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Happy 4th to 🇺🇸 Some shake, rattle and roll going to plant this 🍁 Spotted not by me but @DJuliusSF.
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Promoting science for the next generation - a main goal of the @KavliFoundation. Curiosity starts with kids @KavliPrize banquet
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And both of these gentlemen create sensational sounds playing the trumpet🎺🎺. 🙉Congrat to both of you.
Rosenstiel Award goes to @ardemp and @DJuliusSF for "fundamental and far-reaching studies of the molecular mechanisms of touch, temperature and pain" @UCSF @scrippsresearch @HHMINEWS @BrandeisU
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So Inspired by these young scientists from across our nation. Our faculty @UCSF and @GladstoneInst @seemaychou @genophoria @TejalDesaiUCSF @OphirKlein and many more helped make this event a great success!.
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👍 for upload to @biorxivpreprint by @herber_candice after advisor stalled for 5 yrs due to IP COI. Trainees SQUASH this repressive behavior, DEMAND academic right to publish your work, and TAKE back your career trajectory. Pls. RT.
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Thank you @Ucsf_Biochem for launching the @UCSF Friday Faculty Lunches IN PERSON (with social distancing etc) - what a treat to hear our colleague Adam Frost present on Progeria, lamin and escort proteins. Attention span easily 🔼100-fold over Zoom!
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What an honor to visit @UVA and meet grad students @UVA_BIMS Biomedical Graduate Program for the Larner Lecture - hosted by M. Bland and chaired by @baylissDoug.
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@kate_richerson Note the data for some institutions such as @Columbia show a 4x difference between men and women. Maybe start up packages for women should be 400% higher at these institutions.
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Pretty sure our Deans and Ex-Deans @ucsf are all on the same page when it comes to #DiversityInSTEM #WomenInSTEM.
Keep talking. This will make it only easier for us to recruit the best to @UCSF and raise money from donors.
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History with my mom visiting her outdoor playground that she left on November 1941 - a month before @PearlHarborOahu
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TODAY 1/31/19 @UCSF @Ucsf_Biochem - The 2019 Byers Award Lecture in Genentech Hall at 4:00 PM given by Hana El-Samad, an awesome UCSF Woman doing Basic Science.
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APPLY! 1st Review begins 12/1/21. Check out the science and faculty @UCSF CMP Department - DM any of us for more info:.@FaranakFattahi.@FujimoriLabUCSF.@AWilliamslab.@hollyingrahamSF.
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Major use of @biorxivpreprint squashed unless we take action. As two of my @UCSF colleagues just learned @NIH and @CSRpeerreview DISALLOW submitting preprints in supplemental materials prior to review. Must be cited in Bio or App at time of grant submission.
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Inspired to do more after visiting the Gandhi Smriti - a museum and site where Gandhi was assassinated. Powerful words during our trip hosted by @TNQTechnologies
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The Brain Body meeting @CSHL was the best. Diverse in scope, great talks and posters with blooming dogwood at ever turn. Repeating in 2026?
Brain-bone communication and a potentially exciting treatment for osteoporosis and other conditions. Jan Witkowski interviews @hollyingrahamSF (who reminded us that 5y survival after a broken hip is <50% in older men. )
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