Stephen Fried JHU
@fried_lab
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Asst. Prof of Chemistry🧪 & Biophysics @JohnsHopkins; we ❤️ proteins; unofficial lab rabbi ✡️; ally 🏳️🌈; #TeamMassSpec; organizing @SSP2024 - join us!
Baltimore, MD
Joined March 2019
Why is there so much disorder in eukaryotic proteins? What is its relationship with condensates? Why can some proteins be saved but others get degraded? After years in the making, we think we have answers and they're all connected. Excited to share a 🧵:
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And that’s a wrap! It was a lot of work to put together, but was a great conference in the end! Thanks @broadinstitute for hosting @SSP2024. Next year in Italia 🇮🇹!
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Congrats to @fried_lab Edgar Manriquez @JHU_Mol_Biophys for winning a poster prize at @SSP2024 for his work with James Berger’s team on TOP2 condensation! #FriedLabNews
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RT @theliulab: Deeply honored to receive the MCP Lectureship award at @SSP2024. Thank you for this incredible opportunity to share our work…
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Third and final day of #SSP2024. Ed Huttlin @HMSBioPlex and Katja Luck @imbmainz kick things off modeling the whole human interactome. Integrating mass spec and AI, it feels like the future has come early!
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Congratulations to the six #SSP2024 poster award winners on your top-notch pioneering work! And thank you to @naturemethods and @JProteomeRes for supporting these awards and these promising scientists!
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Nevan Krogan @KroganLab @GladstoneInst @UCSF keynotes the first day of @SSP2024 with a manifesto on the universality of PPIs in human disease. “Every protein is important. And every protein is connected.” #TeamMassSpec #Proteomics
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RT @EveryWhereChem: Thanks to the @HubJHU for sharing my news... Johns Hopkins chemist Rigoberto Hernandez elected president of @AmerChem…
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Lan Huang @UCIrvine and @RappsilberLab kick off #SSP2024 with two talks on new trifunctional XL technology and in-cell XLing to discover new biology and annotate genes of unknown function! #TeamMassSpec
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#SSP2024 is almost here! Last thing to do is stapling together programs @broadinstitute with @FJ_OReilly and @Malvina_Pap! See all 235 of you tomorrow! #TeamMassSpec #proteomics
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RT @kdrew: Excited to share our preprint describing hu.MAP3.0. Here we integrate >25k mass spectrometry experiments to place ~75% of human…
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What can biophysics tell us about the Origins of Life? We brought together some of the leading minds in the field to @stonybrooku @LauferCenter to discuss. Many thanks to colleagues from traveling far & wide and @templeton_fdn for generous support
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Definitely gonna give this a try!! #FragPipe
Rethink the analysis of DDA data! Blurring the boundary between DDA, WWA, and DIA, #MSFragger-DDA+ Enhances Peptide Identification Sensitivity with Full Isolation Window Search. Fully integrated in #FragPipe, simply annotate your DDA files as DDA+ and RUN.
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One of the most fun and insightful collaborations! Beautiful work @shaharsu and glad @fried_lab could pull you into #TeamMassSpec proteomics 😊. @NSF
📢New paper alert!! With @boothbylab @alexholehouse @fried_lab we take a look at how an entire proteome survives desiccation. TLDR: Desiccation tolerance is encoded in specific residues on the protein surface, and occurs primarily in biosynthetic enzymes.
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A happy day for all protein folders out there! Now the question is can we ever figure out how to fold fitted sheets 😜?
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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Was one of my favourite talks at @BiophysicalSoc 2024! Congrats to the authors! 🎉
It was a long time (18 years!) waiting for this demonstration, but it's out, thanks to the leadership of @chancao123 and the great work of Verena Rukes, Mathieu Rebeaud and Louis Perrin. Entropic Pulling at single molecule resolution!
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Final days to register for #SSP2024! See you there 😄
Do you like proteomics? Do you like structural biology? Then you SHOULD be joining us in #Cambridge @broadinstitute for #SSP2024! Registration deadline is coming up soon, this Friday, 4th Oct. Note there will be no on-site registration. Get excited for the biggest SSP to date!
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@taghioskoui Hey I totally believe the scientists doing this work are doing great work with utmost integrity- but I also believe CASP was a great model for community-driven science that led to common benchmarks and an excellent outcome (AlphaFold2)
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