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Stephen Fried JHU Profile
Stephen Fried JHU

@fried_lab

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Asst. Prof of Chemistry🧪 & Biophysics @JohnsHopkins ; we ❤️ proteins; unofficial lab rabbi ✡️; ally 🏳️‍🌈; #TeamMassSpec ; organizing @SSP2024 - join us!

Baltimore, MD
Joined March 2019
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@fried_lab
Stephen Fried JHU
1 year
Why is there so much disorder in eukaryotic proteins? What is its relationship with condensates? Why can some proteins be saved but others get degraded? After years in the making, we think we have answers and they're all connected. Excited to share a 🧵:
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@fried_lab
Stephen Fried JHU
2 years
What makes these amino acids different from all the other amino acids? Together with our collaborators @KlaraH_lab , we think we know. The answer is foldability. Protein folding steered the course of the Origin of Life, out now in @J_A_C_S .
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Stephen Fried JHU
3 years
Very excited to share that our work on Protein Nonrefoldability is out today in @J_A_C_S ! #AlphaFold might be great at finding proteins' native structures... but turns out many proteins themselves are not! Short 🧵1/7
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@fried_lab
Stephen Fried JHU
3 years
Feeling so thankful for our new baby girl!! #HappyThanksgiving #FriedLabNews (well more like FriedFamilyNews!)
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@fried_lab
Stephen Fried JHU
2 years
Excited to share our story out in @NatureComms in collab. with Ed O'Brien's lab @psu_chemistry led by the amazing Dan Nissley @OxfordStats . We show that many E.coli proteins can misfold in subtle ways that would bypass the proteostasis network. Short 🧵
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@fried_lab
Stephen Fried JHU
3 years
When I was a student, I hated troubleshooting. Now as a Jr. PI, that’s what I do: I’m the troubleshooter-in-chief. But now I like it. Why? 1) it’s easier when you have more psychological distance from the failed result. 2) the joy on a student’s face when you help them solve it
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@fried_lab
Stephen Fried JHU
3 years
In taking time away from work because I need to (or want to) spend time w/ Liora, I have found a special camaraderie with female colleagues and scientific heroes. Because of the work YOU did over the past generation, we are ALL beneficiaries. Gender Equity is Equity for Everyone
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@fried_lab
Stephen Fried JHU
3 years
We are over the moon to introduce our baby girl: Liora Ilana Fried (ליאורה אילנה פריד)! This name is very special to us...
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@fried_lab
Stephen Fried JHU
7 months
Honoured and proud to be part of the 2024 cohort of #SloanFellow s! Would not have been possible without mentors, collaborators, and brave graduate students willing to take on new ideas and try difficult experiments. Thank you @SloanFoundation ! @JHUChemistry @JHU_Mol_Biophys
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@fried_lab
Stephen Fried JHU
4 years
Very happy to share that our @NSF #CAREER proposal has been selected for funding! @fried_lab will be “leaving the fold” and exploring #proteinFolding on the #proteome scale with mass spec. Big thanks to @PtoChem for initiating, mentors @JohnsHopkins & reviewers! #FriedLabNews
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@fried_lab
Stephen Fried JHU
6 months
If you teach a biochemistry class, consider adopting the terminology of Watson-Crick-Franklin base pairing 👩‍🔬 🧬. It rolls well off the tongue. Your students will appreciate it. And we can do a small part to right a bad scientific injustice from the previous generation.
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@fried_lab
Stephen Fried JHU
5 months
Just submitted my tenure dossier! And now onto taxes! 😆 #FriedLabNews @CbiJhu @JHU_Mol_Biophys @JHUChemistry @JHUArtsSciences
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@fried_lab
Stephen Fried JHU
2 years
#USHUPO2023 was my first @us_hupo but certainly will not be my last! We in proteomics are lucky to have such a fun and supportive community. The PI poster session is a great idea: helps lower barriers for trainees to interact with PIs; more conferences should try this!
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@fried_lab
Stephen Fried JHU
3 years
Hey directed evolution people, our little improvement to error-prone PCR is published in Analytical Biochemistry. Potentially useful to some of you. Great work to @fried_lab 's Sea On Lee for discovering this. A short 🧵: 1/5
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@fried_lab
Stephen Fried JHU
4 years
Honored and excited to share the news that @fried_lab will be receiving the @NIHDirector 's New Innovator Award to "Watch proteins fold (and misfold) in vivo with crosslinking mass spec!” @NIH_CommonFund #NIHHighRisk @NIH @JohnsHopkins #FriedLabNews . 1/n
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Stephen Fried JHU
1 year
Thank you @dreyfusfndn for recognizing our work - none of which would be possible without amazing students, colleagues, and collaborators. Congrats to all awardees, looking forward to meeting y'all! #FriedLabNews @JHUChemistry @CbiJhu @JHU_Mol_Biophys
@dreyfusfndn
The Camille and Henry Dreyfus Foundation
1 year
Congratulations to Dr. Stephen Fried, @JohnsHopkins , for being named a 2023 Camille Dreyfus Teacher-Scholar! @fried_lab @JHUChemistry #DreyfusAwards
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@fried_lab
Stephen Fried JHU
2 years
Excited to share that Proteome-wide Photo-crosslinking Mass Spec (💡⚔️-⚖️📊) is now a "thing!" Thanks to @AphettoChemist & @rx_piyoosh , we can now visualize protein networks and quinary interactions at residue-level resolution in cells. 1/8 #TeamMassSpec
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@fried_lab
Stephen Fried JHU
2 years
Science is about people. The scientists who get this are the greatest scientists.
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@fried_lab
Stephen Fried JHU
2 years
Okay yes, I also got these books along with all the other needy parents. I can assure you they are great fun, and your baby will learn no QM (so don’t have to worry about any spoilers). Can we please get Proteomics For Babies now? 😅
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@fried_lab
Stephen Fried JHU
3 years
Filling out recommendations for my undergrad applying to grad school... Just want to say: big shout out to @UChicago 👐for NOT asking those goofy numerical questions that pigeon-hole students. More unis should do this. @AcademicChatter #phdlife
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@fried_lab
Stephen Fried JHU
1 year
Some exciting news from @fried_lab undergrads, who have been up to wonderful things! Update #1 : Our amazing Ashma Pandya will be headed to @CalTech / @NASAJPL for grad school as an @NSF #GRFP pre-doctoral fellow, to continue her explorations of astrobiology. 1/4. #FriedLabNews
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@fried_lab
Stephen Fried JHU
3 years
Don't think I've announced this yet... but here is my registration to @GordonConf #ProteinFolding #Dynamics ! Life's dynamics are going to get a lot more complicated soon! 😅 (Oh and BTW, registration is open for GRC PFD... check it out, it will be an amazing program!)
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@fried_lab
Stephen Fried JHU
7 months
This is what a new fellow of the ⁦ @BiophysicalSoc ⁩ looks like! Congrats Gary, ⁦ @uncchemistry ⁩: One of a remarkable class of inductees. #BPS2024
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@fried_lab
Stephen Fried JHU
2 years
Very excited to share our team's work @BiophysicalSoc #FutureOfBiophysics , along with friend and inspiration, Lauren Porter! See you all in San Diego! #FriedLabNews @JHU_Mol_Biophys @JHUChemistry
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@fried_lab
Stephen Fried JHU
5 months
1 yr ago, a talented Turkish biochem student emailed me that she was passionate about #ProteinFolding ... and now İdil Demiralp will be starting grad school at @scrippsresearch ! So happy @fried_lab could be a small part of your scientific journey! Good luck, İdil! #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
It's official– @fried_lab is the FIRST to get trained on the @Quantum_Si single-molecule protein sequencing platform! Great work to @ManriquezEdgar loading our first chip with peptides. Excited for what we will discover on this cool new platform! #FriedLabNews @JHUChemistry
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@fried_lab
Stephen Fried JHU
3 years
#Folding can be hard. Fortunately E. coli proteins #DontHaveToFoldAlone . The cytosolic medium and its chaperones can ~nearly~ fully restore an unfolded E. coli proteome. In our new preprint, we show how. Short thread 1/8.
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@fried_lab
Stephen Fried JHU
4 years
Super excited that our story is finally out in . @NatureBiotech ! By combining bioinformatics with a new screening method, we have upped the number of orthogonal tRNA/synthetase pairs for #geneticCodeExpansion from 3 to 8!! . #FriedLabPubs 1/n. . @MRC_LMB
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@fried_lab
Stephen Fried JHU
3 years
To my amazing partner, Daniela: you are my HSP70. When I’m all tangled up, you straighten me out… and then let me slowly become myself again. You are essential to my viability. 🥰😅 #AcademicChatter #proteinFolding
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@fried_lab
Stephen Fried JHU
3 years
Big congrats to @fried_lab ’s Sea On Lee and April Xia who both received #bps22 travel awards @BiophysicalSoc !! Come hear them talk about loopable translation and crosslinking mass spec on the nonrefoldable proteome! #FriedLabNews
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@fried_lab
Stephen Fried JHU
6 months
So proud of @AphettoChemist for brilliantly defending her PhD this week! Anneliese demonstrated high-res proteome-wide photo-crosslinking is possible, and the field of structural biology is transformed because of her! Mazel tov 🎉 ❤️ #ProudPI #FriedLabNews
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@fried_lab
Stephen Fried JHU
9 months
Particularly proud of this report in @JPhysChem on how we are lowering the barrier to students' success in physical chemistry. If you teach p-chem, and want to help diversify our discipline and enrich students' experience, please read and join #LABSIP !
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@fried_lab
Stephen Fried JHU
3 years
Everything in science is harder to do than your PI thinks. My old advisor used to say "That will take 1 picosecond to do, right?" 😅 Answer: No. (It takes the molecule 1 picosecond to do it, and me much longer to understand why.)
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@fried_lab
Stephen Fried JHU
4 years
Really honoured to share our work on non-refoldability with @bioplymrsinvivo #BPS2021 . Thank you to everyone there for your thoughtful questions! Really looking forward to Day 2.
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@fried_lab
Stephen Fried JHU
3 years
Very sad to miss all of you cool #biophysicists at #bps22 this year, esp. today’s amazing @bioplymrsinvivo program. Though on the flip side, you don’t get to hang out with Liora- so maybe an even trade? 😜 I’ll catch you next year or perhaps earlier @GordonConf !
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@fried_lab
Stephen Fried JHU
4 years
Really honoured to be selected for this award and to join other incredible biophysicists @dallandrummond @LisaMJonesLab1 . Thank you so much to the academy! 🤣 🎉 And to @fried_lab for all your creativity and hard work to make this possible!
@bioplymrsinvivo
Biopolymers In Vivo
4 years
📣Very happy to announce that Stephen Fried @fried_lab from @JHUChemistry is the winner of the 2021 @BiophysicalSoc BIV Young Investigator Award!🏆🎊🎉
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@fried_lab
Stephen Fried JHU
2 years
Congrats to @fried_lab 's Sea On Lee for successfully defending her dissertation AND for being awarded a Gompf Family Fellowship from @JHUChemistry ! You really impressed your committee and set a high bar for all future grads from the group! 🎉😁 #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
Feeling very happy today 😁; two stories that had long (and at times bumpy) roads both got accepted! Will share tweetorials in due course... for now, just want to thank the peer reviewers out there who (1) are willing to listen to new ideas; (2) want to make papers BETTER. 🙏
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@fried_lab
Stephen Fried JHU
4 years
Coming back home to Baltimore from Wilmington, DE. What an incredible opportunity to hear #JoeBiden and #KamalaHarrisVP address our divided nation with hope and humility. #Election2020 “Now is a time to heal.”
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@fried_lab
Stephen Fried JHU
4 years
Hey all, some good news! Today, I am Assistant Professor (by courtesy) in the Department of #Biology . @JHUArtsSciences . Excited to do some awesome proteomics experiments with these great supportive colleagues: @microjoce @rkuruvi1 @tatkatrcek + more. #JohnsHopkins #FriedLabNews
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@fried_lab
Stephen Fried JHU
1 year
And one belated #FriedLabNews — major congrats to Sea On Lee for being our very first Doctor to graduate from the lab! ⁦ @JHUArtsSciences ⁩ hooding ceremony was beautifully done. Was my 2nd time ever wearing ⁦ @Stanford ⁩’s gown (hard to hide in it!) To many more!
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@fried_lab
Stephen Fried JHU
2 years
Big mazel tov to @fried_lab 's Divya Yadav for getting an ACS travel reward to attend #ACSSpring2023 in Indy! Divya has done a proteome-wide assessment of cotranslational protein folding and will be sharing it for the first time! #FriedLabNews @JHUChemistry
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@fried_lab
Stephen Fried JHU
2 years
Blast from the past! ⁦ @DrJ_RNA ⁩ and I first met in ⁦ @lindaunobel ⁩ 2013. At the time we said- would be cool to postdoc abroad and then come back. Decade later - seeing her at #bps2023 made my day
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@fried_lab
Stephen Fried JHU
7 months
Congratulations Steve Boxer @stanford on receiving the ⁦ @BiophysicalSoc ⁩’s founders award! Very happy we had a chance to reconnect lab alumni and friends from several generations! #BPS2024
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@fried_lab
Stephen Fried JHU
8 months
So excited to be co-organizing the 2024 Symposium for #StructuralProteomics with @FJ_OReilly & @Malvina_Pap at @broadinstitute in October! Save the date (28-30 Oct) for this event bringing together leaders in structural mass spec, cryoET, comp. structure prediction, and more!
@SSP2024
SSP 2024
8 months
Save the date for #SSP2024 For more information:
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@fried_lab
Stephen Fried JHU
3 years
I am so excited by the mission of this @RCSA1 program and grateful for the opportunity to be part of the #CotttellScholar cohort. There is a lot of work to do to improve equity and learning outcomes in STEM! Looking forward to meeting the other scholars.
@RCSA1
Research Corporation for Science Advancement
3 years
RCSA has named a diverse group of 24 early career teacher-scholars in chemistry, physics and astronomy as recipients of its 2022 #CottrellScholar Awards. Each awardee receives $100,000.
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@fried_lab
Stephen Fried JHU
2 years
Exited to share with y'all that @ManriquezEdgar 's program for accurately assigning domain architectures, DomainMapper, is now published! Code is on github. Pretty easy to install use. Hope that you find it useful, and happy to get feedback. .
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@fried_lab
Stephen Fried JHU
6 months
#ProudPI moment! Haley Tarbox explains to @us_hupo her data showing a general connection between cognitive decline and protein misfolding. Come find her to get your LiP-MS questions answered! @impetusgrants @NIGMS
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@fried_lab
Stephen Fried JHU
3 years
First-ever @fried_lab #yoga 🧘 led by the fabulous Divya Yadav in beautiful Keyser quad!! @JohnsHopkins @JHUChemistry #MentalHealthMatters #Humpday #FriedLabNews
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@fried_lab
Stephen Fried JHU
4 years
Tissue culture room in @fried_lab is becoming a thing! Excited to start exploring #proteinFolding in the context of human health and disease. #FriedLabNews
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@fried_lab
Stephen Fried JHU
1 year
The secret is disorder. The more disorder a protein has the better it refolds (like a built-in chaperone). Yeast proteins have higher levels of disorder than E. coli's, and this neatly explains why they refold better. Same goes for N. crassa, another fungus. 4/10
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@fried_lab
Stephen Fried JHU
2 years
Great time had by all at Gibbs36! @rx_piyoosh 's first conference in USA, Haley Moran gave a great talk on Tuesday, @ManriquezEdgar shared news with friends about his Prot.Sci. paper getting accepted. Looking forward to next year's! #FriedLabNews
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@fried_lab
Stephen Fried JHU
4 years
Do you like #massSpec and #biophysics ? Registration is now open for the @BiophysicalSoc workshop on "Mass Spectrometry in the Cell!"
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@fried_lab
Stephen Fried JHU
4 years
Our lab’s first paper (with @KarenFlemingPhD lab) was accepted in @PNASNews !! Big congrats to @DaganMarx and @Anneliese_MTG for driving this really thought-provoking collaboration. #FriedLabNews
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@fried_lab
Stephen Fried JHU
6 months
What an amazing two days at @WashUChem and @WUSM_BMB , where I had the pleasure to be hosted by friends @jenheemstra and @alexholehouse and meet many other amazing scientists doing trailblazing biophysics. Thank you for a lovely visit!
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@fried_lab
Stephen Fried JHU
2 years
Celebrating with the Biophysics crowd of PHYS #ACSFall2022 @LouMalnatis #Chicago !! Great times and conversation with ⁦ @thedavislab ⁩ ⁦ @PRESSELAB ⁩ ⁦ @TarasPogorelov ⁩.
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@fried_lab
Stephen Fried JHU
1 year
Can we teach bacteria to autonomously synthesize and assemble biomaterials? @Qi_Xieqi and coworkers thing so! Excited to share our work on secretion-catalyzed assembly, out now in @angew_chem . Bacillus's translocon can act like a nano silk spinneret!
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@fried_lab
Stephen Fried JHU
1 year
Many of you have asked; now we are beginning to work on it! Xinzhe gives his 1st group meeting to @fried_lab on methods to probe phospho and glyco on protein folding. Thanks to @us_hupo colleagues @riley_nm1 @GarciaLabMS who inspired us to take on this new direction. #glycotime
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@fried_lab
Stephen Fried JHU
4 years
New grad student doing first Western Blot in the Lab. Me on Slack: Is all well on the Western front? 🤪🤠 #AcademicChatter
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@fried_lab
Stephen Fried JHU
3 years
First lab social since Christmastime 2019!! Thank you 🙏 all for your culinary 🍲 skills and for vaccines 🧬💉that make it possible! Grateful for the chance just to all be together and chat. What’s next??— camping trip? #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
These awesome authors just submitted their manuscript, and took my suggestion to take the afternoon off! Look out for a tweet on the pre-print soon! #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
For proteins that can refold spontaneously (like most engineered FPs), folding may not be so sensistive to translation speed. I would be very careful about extrapolating this result to complex proteins whose folding is affected by translation schedule.
@NicoC_MicSynBio
Nico Claassens
2 years
See our latest work on the influence of codons on gene expression. Full codon-randomization of a gene in E. coli shows only the first 8 codons really matter! Freely adapting Bill Clinton slogan: It's the first few codons, stupid!
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@fried_lab
Stephen Fried JHU
2 years
First in-person @fried_lab group meeting in... two years😅! (slightly embarrassed to admit -better late than never tho, right?) Thank you @DivyaYa09490300 for kicking it off with some exciting updates on your new project! #FriedLabNews
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@fried_lab
Stephen Fried JHU
3 years
Really happy to share that @fried_lab UG alum, recent @JHUArtsSciences grad, John Abili, will be starting soon at @Regeneron . First lab alum to get a 'real' job!! 😅🎉 Good luck and stay in touch! #FriedLabNews @BlackInBiophys
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@fried_lab
Stephen Fried JHU
1 year
Very excited for the opportunity to continue work with @KlaraH_lab and @ELSI_Fujishima on Origins of Life work with support from @HFSP . Looking forward to traveling more and seeing y'all in Prague and Tokyo. #2023HFSPAwardee #FriedLabNews
@HFSP
HFSP
1 year
It's official! The 2023 #HFSP New Awardees are here! Congratulations to the 34 winning teams of #HFSPResearchGrants and the 52 researchers awarded #HFSPFellowships ! 🥳Are you a #2023HFSPAwardee ? 🏆Tell us! +info:
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@fried_lab
Stephen Fried JHU
3 years
Really excited to kick off #FiGURE (first-gen undergrad research experience) today! Six @JohnsHopkins freshmen will be exploring protein folding throughout the Tree of Life, and joined their first group meeting today. Looking forward to see what you discover! #FriedLabNews
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@fried_lab
Stephen Fried JHU
1 year
We're lucky to have some awesome summer students in @fried_lab ! Joy Brewer is refolding Bacillus proteomes whilst Mark Fakler and İdil Demiralp are figuring out how protein structures get perturbed when chaperones are missing. Excited to learn what y'all discover. #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
Statements to this effect seem to have become fashionable lately. "Science is on the decline." "Progress is slowing down." @ezraklein interviewed Pat Collison on so-called "Progress Studies" to the same effect. These thinkers are missing something very basic and are very wrong
@maxdkozlov
Max Kozlov 🇺🇦
2 years
'Disruptive' science has plummeted — and no one knows why. Research in the 2000s is much more likely to incrementally push science forward than to veer off in a new direction. Check out my latest for @Nature with @russellfunk , @dashunwang , @yian_yin
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@fried_lab
Stephen Fried JHU
4 years
Our new group photo and first time we’ve all been in the same wide-angle lens frame. Big kudos to Qi Xie for this capturing this brilliant shot even with social distance! #FriedLabNews
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@fried_lab
Stephen Fried JHU
4 years
Happy #YearOfTheOx to our students of Asian heritage! You contribute so much to the scientific community of @JHUChemistry (and across the US)! This year, may you stay 💪as an 🐂 when experiments go wrong; sometimes a little stubbornness and bullheadedness can go a long way 😁
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@fried_lab
Stephen Fried JHU
3 years
Thank you @fried_lab for making my birthday special with such a clever gift and beautiful card! I’m lucky to have you all! #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
An important read for anyone interested in enzyme mechanism from my PhD mentor (twitterless Steve Boxer @StanfordChemis1 ) and the talented Zhe Ji! The electric field catalysis model explains evolution of beta lactamases.
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@fried_lab
Stephen Fried JHU
2 years
@fried_lab ⁩’s Haley Tarbox ⁦ @CbiJhu ⁩ gave a fun and exciting lightning talk at ⁦ @us_hupo #USHUPO2023 ! Come to her poster to learn about the molecular basis of cognitive decline. #FriedLabNews
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@fried_lab
Stephen Fried JHU
3 years
Do you want to continue hanging out with cool #biophysicists after your post-doc? Biophysics @JohnsHopkins is hiring! We are trying's @YaleMBB method to try to lower bias & diversify the applicant pool. Consider applying! Please RT. @BlackInBiophys
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@fried_lab
Stephen Fried JHU
3 years
So excited that this is out in @NatureSMB ! Firstly, a HUGE shout-out and thanks to the amazing @valendraica , @S4yanDas , Greg Bowman, and Ilana Nodelman for their #CryoEM wizardry 🪄. So what can you learn about nucleosome remodeling at 2.3 Å? It turns out, QUITE A LOT. 1/5
@valendraica
Jean-Paul Armache
3 years
Very excited that our paper is finally out in @NatureSMB ! Working together with Ilana Nodelman, Greg Bowman, @fried_lab , @AphettoChemist and @s4yandas , we were able to solve the nucleosome-bound yChd1 at 2.3Å 1/2
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@fried_lab
Stephen Fried JHU
4 years
First time in the office since March 17. Was starting to miss this place! Thanks to ⁦ @JHUArtsSciences ⁩ for permission to commence a #COVID19 project. Working with Matthias Heyden & Carlos Simmerling to stop SARS-CoV-2 by throwing a wrench in its #ribosome #frameshifting
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@fried_lab
Stephen Fried JHU
2 years
Big shout-out to ⁦ @fried_lab ‘s ⁩ ⁦ @PtoChem ⁩ , April Xia, and Atharva Bhagwat for venturing to #PS36 @ProteinSociety ⁩! If you’re there, go meet with these awesome rising young scientists to learn what biophysical properties help proteins refold!
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@fried_lab
Stephen Fried JHU
2 years
We’re 3 for 3! All of the 2nd years have passed their GBO exams and are ready to dig more into their projects! Congrats Haley, April, @ManriquezEdgar ! #FriedLabNews
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@fried_lab
Stephen Fried JHU
3 years
Sad that it’s the last day of FiGURE (first-gen undergrad research exp)! Was such a pleasure to teach brilliant @JohnsHopkins freshmen about #LabLife & #ProteinFolding ! Excited to see what we discover in your data. @NSF -funded #MCB .
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@fried_lab
Stephen Fried JHU
3 years
Thank you @fried_lab for the nerdiest (and my personal favourite) gift for Liora!! #FriedLabNews
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@fried_lab
Stephen Fried JHU
6 months
Just submitted our first manuscript to @PRX_Life ! -actually first time ever to an @APSphysics journal. Looking forward to connecting more with the community of physical biologists that this journal is coalescing together. (Wish us luck with our reviewers! 😅)
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@fried_lab
Stephen Fried JHU
5 years
Big news! It's @fried_lab 's first publication (or at least pre-print!) Working with @KarenFlemingPhD 's group, we used #XLMS and #SANS to see how one 'groove-y' periplasmic chaperone works! #FriedLabPubs
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@fried_lab
Stephen Fried JHU
1 year
We unfolded yeast's proteome and challenged it to refold spontaneously. The result? 🥁... Yeast proteins are surprisingly efficient refolders, much BETTER than E. coli's, despite being larger, having more domains, & more β content. How can this be? 3/10
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@fried_lab
Stephen Fried JHU
11 months
We made it! @fried_lab has trekked to Carbondale for the 37th annual Nerds in the Woods (AKA, #Gibbs #Biothermodynamics conference). Looking forward to digging into some exciting science from old friends and new acquaintances! #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
I seldom tweet political but I am so proud of Kansans for voting down an amendment that would have removed constitutional protections for the right to have an abortion in a decisive 60-40 split.
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@fried_lab
Stephen Fried JHU
11 months
More #FriedLabNews : Big congrats to @fried_lab students Edgar Manriquez and Yilin Shen for getting travel awards to give talks at @ABRCMS ! They're going to talk about some new improvements to the @Quantum_Si protein sequencing technology and #chaperones
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@fried_lab
Stephen Fried JHU
4 years
I ams SO PROUD of @fried_lab 's first three students, @PtoChem , @Anneliese_MTG , and Sea On Lee ALL becoming Ph.D. candidates at @JohnsHopkins ! You three inspire me with how much you've grown as scientists in 2 years! #FriedLabNews #phdchat #AcademicTwitter
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@fried_lab
Stephen Fried JHU
7 months
@fried_lab shows up for #BPS2024 ! I remember how special it was when as a grad student the whole lab traveled together to the ⁦⁦ @BiophysicalSoc ⁩ meeting when it was close. So happy I have the chance to carry on that tradition! #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
My brother taught me that short toasts are always the best. So this one was simple: “To new friends” #BPS2023 #SanDiego
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@fried_lab
Stephen Fried JHU
2 years
@fried_lab undergrads are going to #GradSchool ! Patrick Prochazka will be starting at @DukeMedSchool and Nitya Vissamsetti is heading to @UChicagoBMB ! So proud of you both 😇; it has been a pleasure to see you grow as scientists! #ProudPI #FriedLabNews
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@fried_lab
Stephen Fried JHU
2 years
Congrats to Edgar and Divya for running in the Baltimore half-marathon. You both can run circles around me!! #FriedLabNews
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