John Haughton MD, MS 🌻
@doc4care
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Health better for all. Geriatric Rehab Physician, payer, patient, engineer, family, friend. WorkFocus: #longcovid/inflammation #pophealth #riskadjustment/HCC
Annapolis, MD
Joined February 2011
Thread attached about how the “confused” immune system drives covid / long covid and some things that can be done now to help reverse it. #LongCovid #Treatment #Science
1/n - Easier way to see TLR4 impact from viruses (TLR4 generally reacts to LPS and causes inflammation in sepsis. Some viruses - 4 shown in this paper “turn o TLR4 too”. (The confusion talked about in immune response in Covid?) k
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RT @RepGregMurphy: Tax-exempt @NYULangone’s $8 million Super Bowl ad caught my eye, and I have questions. I’m asking the hospital system a…
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RT @NBoydGibbins: Our approach: Building a database that links molecular disease signatures with deep patient classification data Using ML…
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Attached article with deep Evaluation of metabolic pathways in mecfs vs control at rest, exercise w/wout PEM. Has subgroup pathway analysis too.
More evidence that #MECFS is a brain disease. This is also a good study to review for those who continue to say that MECFS is simply deconditioning. One of the study's conclusion is: "Exercise led to consumption of lipids in ME/CFS and controls while metabolites were consumed in ME/CFS but generated in controls."
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@dullunlivin @newtgingrich @EpochTimes 1) new longevity institute. 2) Path to intervention approval that crosses conditions. 3) Funding to study the underlying drivers of aging. Good policy to help Baby boom population avalanche.
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RT @beappbeapp: It's been a busy start to the year for us at @theA4LI as we continue to push for these bold initiatives and set the stage f…
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RT @drpablocorral: 🤔Could IL-6 inhibition be the next frontier in CVD therapy? 👉IL-6 and Cardiovascular Risk: A Narrative Review ☝️Evide…
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@scott_scientist Agree, can.t be the sole root cause (and functionally, an inflammation and microclot instigator in most vs ongoing cause). And as you do too, so important to approach from a systems perspective.
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RT @MVGutierrezMD: Impact of NIH funding in Texas: NIH AWARDS FUNDING: $1.85 B JOBS SUPPORTED: 29,563 ECONOMIC ACTIVITY SUPPORTED: $5.8 B…
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RT @TheNicotineTest: Reminds me of @remissionbiome @RenegadeRes Euphoria =Remission Event...similar to what 25% of users of low-dose nicot…
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@seanstidston And could do it every other day for the first couple of tries (so if issues can clear it faster). Note - many have gi / gas for a week or two. Less at lower dose, such as 500/day
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@seanstidston It.s “both and”. U shaped dose response. And if someone is already inflamed and with damage/less reserves can cause issues at lower dose. If using for inflammatory reasons, in such situations as long covid or mecfs, makes sense to try small doses 1st to see what happens.
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@RenzPolster Looks as if it quiets MTOR ( other approaches include rapamycin direct effect and metformin or berberine indirect effect via AMPK). Though is quieting MTOR increases Autophagy and gets rid of dead tissue residual in area of TBI - so it doesn’t increase local inflammation.
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