Charles Gersbach
@cgersbach
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Professor of Biomedical Engineering at Duke University, Director of the Center for Advanced Genomic Technologies
Joined April 2011
We're very excited to launch of the Duke Center for Advanced Genomic Technologies @DukeCAGT, a joint venture of @DukeEngineering @DukeMedSchool and @DukeTrinity. We are supporting collaborative research efforts to tackle grand challenges in genome sciences and engineering.
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Led by Sean McCutcheon, Dahlia Rohm, and Nahid Iglesias - we are thankful to the editors and reviewers for their contributions to enhancing this review.
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We explain the technology and its context among other genome editing tools, provide a catalog of common epigenome editors, survey recent technical advances, and summarize use cases in functional genomics, cell engineering, and gene/cell therapy.
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Epigenetic control is incredibly powerful for bolstering cell therapy. We’re very excited to continue to build on the foundation established with this publication.
Scientists have engineered a modified CRISPR technology targeting the epigenome capable of modulating T-cell behavior. In the process, they discovered a master regulator of the genome that reprograms T cells and enhances their cancer cell-killing ability.
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RT @MyBioTechniques: Using a new CRISPR-based methodology, a team of researchers led by @cgersbach @DukeU has identified a “master regulato…
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RT @NatureBiotech: Epigenetic CRISPR screening in human T cells reveals that BATF3 overexpression enhances T cell function, reduces exhaust…
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We are incredibly thankful to our collaborators and co-authors, and our funding sources for supporting this new research direction! @somaticediting @ENCODE_NIH @IGVFConsortium @genome_gov @NSF @AllenInstitute @DukeU @DukeCAGT
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Looking forward to a great meeting!
FGE23 @bitsgoa is less than a week away and the whole team @IGIBSocial is excited to welcome guests and participants from all over the world! @BKleinstiver @palermo_lab @randall_platt @cgersbach @AngelaEGGLEST17 @XueSherryGao @Ajit_IISER @MohankumarKMur1 @WeixinT @KomorLab
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