Susan Hopkins
@SMHopkins
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Infectious diseases clinician & epidemiologist, Chief Medical Advisor @UKHSA , (also work @RoyalFreeNHS @UCLInfectImm ). Hon CBE. Research:
London
Joined January 2009
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So we have a difficult time ahead of us. Please keep your circle of contacts as small as possible. Wash your hands. Keep your physical distance (back to zoom quiz’s on a Saturday night). And if you can’t keep your distance wear a mask. Each effort counts.
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monkeypox - a short thread.
Firstly a huge thank you to the people coming forward with symptoms, clinicians that are taking samples and helping us find cases, health advisors and health protection teams for tracing contacts, vaccination teams and inpatient management teams 👏
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A short thread on Group A Strep (GAS), invasive GAS (iGAS), scarlet fever and other conditions.
@UKHSA
has released an epi report highlighting what we are detecting through notifications and reports from labs and clinicians 1/8
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Has anyone managed to get “Jesus, Mary and Joseph and the wee donkey” into casual conversation yet? Big effort tomorrow.
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Prof
@SusanMichie
is an expert in her field - she has given her time, expertise and energy to support the UK and global COVID response. Personal attacks on scientists, academics and clinicians are unacceptable.
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Can I just say thank you to every single individual working locally, regionally and nationally to protect the nations health in the ongoing covid19 pandemic. The
@PHE_uk
response officially stood up on 8 January - more than 9 months ago; 24/7 working by dedicated professionals.
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I lead the
#SIRENStudy
and have been studying the impact of prior infection with COVID-19 and COVID-19 vaccinations on immunity for more than 18 months. We have published multiple studies with collaborators. The most recent preprint is available here 1/6
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Tomorrow step 3 of the roadmap commences. This is the biggest step yet and even more uncertainty on how much cases will rise with the B.1.617.2 circulating in our communities. But there are things we can all do to keep case numbers low. 1/3
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Sadly due to Omicron work related activity I was unable to collect in person. Congratulations to all.
Our congratulations to Susan Hopkins on receiving the Presidential Distinguished Service Award today.
#PDSA
#GlobalIreland
@PresidentIRL
@dfatirl
@IrelandEmbGB
@SMHopkins
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I’m going to use this2 thank all
@ukhsa
working on
#Omicron
- health protection teams & lab scientists who are unseen heroes; data scientists, tech, it- who we couldn’t see/analyse the data without; our ops & NCRC staff who coordinate our meetings organised & keep us in line 1/2
Unbelievably, all this work is pulled together into a single coherent thread & risk assessment by the super-human
@meera_chand
@SMHopkins
gives expert insight & oversight of the Technical Briefings
Thanks goes to them both for their tireless work 🙏🏼
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I ❤️ this. We, anyone who works in healthcare, will always be happy to treat people when you come forward. For COVID vaccinations or anything else. That is our job. That is why we do what we do. We do not judge. People are hesitant. Come when U R ready. The sooner the better!
Can I just say, if you're unvaccinated, and change your mind but worried about people judging you at the vaccination center, this will absolutely not be the case.
We will welcome you with open arms.
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Merry Christmas one and all. Thank you all for your support over the last 12 months. Hope everyone working in health, social care and public health manages to get a break as the work we do will continue 24/7 on
#COVID
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Updated technical briefing on
#voc202012
/01 (new variant
#sarscov2
#covid
) now available - amazing work from
@PHE_uk
colleagues over Christmas bank holiday weekend.
@WHO_Europe
@ecdc
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Hurray. My Dad received his COVID vaccine today. Well done Ireland. Now waiting for my mum to be called. And then I will feel calmer about their safety than I have done for the last year.
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Off for my second AZ vaccine this morning. Delighted to get an immune boost and fingers crossed it doesn’t knock my for six for the weekend.
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#SIREN
#vaccine
effectiveness preprint now available
Thank you so much to all the participants, research teams
@NHSEngland
, study team
@PHE_uk
,
@NIHRresearch
#UPH
,
@DHSCgovuk
for supporting this study in your many different ways.
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Anyone else feel a little bit more hopeful for the world tonight?
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1. Work from home if you can
2. Keep your contacts as low as possible
3. Do regular asymptomatic LFD tests
4. If meeting people indoors in peoples houses, open windows and doors and let fresh air in
5. Wear a face covering as much as possible
6. Wash your hands regularly
2/3
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7. Take a PCR test if you have COVID symptoms
8. Isolate with your household if you test positive
9. Give names of all contacts and places visited when asked by contact tracing teams
10 FINAL AND MOST IMPORTANT. Get vaccinated as soon as you meet the age, or other criteria
3/3
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Thank you Tulio and all South African scientists, researchers and government for rapid sharing of your data and insights. It helps us all. Supporting countries to increase sequencing, have labs to grow virus and study, epidemiologists to deliver studies essential. 👏👏👏
Busy day on B.1.1.529 - a variant of great concern - The world should provide support to South Africa and Africa and not discriminate or isolate it! By protecting and supporting it, we will protect the world! A plea for billionaires and financial institutions. 1/8 tweets
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Agree. We are all hoping but we just don’t know. Underlying immunopathology remains uncertain. What is clear is being vaccinated & boosted is essential for our own health. preventing transmission essential for all.
1. Vaccinate
2. Mask
3. Reduce contacts
4. Ventilate
5. Hygiene
For those asking whether this is good/bad news, simple answer: I don't know. While omicron may infect the lung cells less efficiently, a higher viral load may worsen immune response. We discussed the pathogenesis w/
@KindrachukJason
@KrutikaKuppalli
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In this pre-print, which is under peer review, we demonstrate that 2 doses of vaccination on top of prior of infection, significantly reduces both asymptomatic & symptomatic infection compared to infection alone - Table 3 - the longer since primary infection the more effect 2/6
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Festival revellers returning home tonight. I hope you all had a great time. Now take a few steps to protect others on your return.
1. Access asymptomatic testing and do a test regularly (at least twice this week)
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Thank you to everyone who has messaged me over the last couple of days. grateful for all of your support over very many years & especially the last couple. This honour is thanks to all of you in public health & infection community who are tireless in your service and dedication.
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Thank you to all the
#SIREN
participants, research teams in many trusts
@NIHRresearch
@PHE_uk
- antibodies/prior infection protect the majority the majority but not all from reinfection. Keep using
#ppe
#ipc
#handsfacespace
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#covid19
Infection rates are up, hospitalisation rates have increased, more suspected outbreaks are reported. Actions you can take. 1. Get vaccinated if you are offered 2. If you have respiratory symptoms, stay away from those at higher risk of severe disease AND mask up
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delighted the latest
#SIRENstudy
paper is released in
@NEJM
tonight
Firstly, thank you so much to all the Site PIs, research teams, staff & participants at each hospital - we couldn't do it without you.
Thanks funders
@DHSCgovuk
@UKRI_News
@NIHRresearch
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So I’m going to call out all those supporting us in healthcare and around the country - bus & train drivers, shopkeepers, taxi drivers, binmen, utilities to keep us running, cleaners, teachers and many more that will help us all keep going.
#COVID19
#community
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Who else wants an internationally agreed COVID variant nomenclature that is stable over time and describes significant changes better? Similar to storm nomenclature designated by first country. But needs to be consistent, non country specific, consistent and understandable.
@WHO
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When to wear a fluid repellent face mask (FRFM) versus FFP3 mask - poster below. Health and safety exec advise that FRFM can be worn TIL damp and FFP3 for at least an hour (ie more than one patient) But once removed from face (eg to have a drink) then must be disposed safely.
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If they hadn’t come forward and if clinicians had not recognised something unusual we would still be in the dark with no possibility of preventing spread. This is sexual health and public health in action.
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Can’t believe how far we have come in 13 months… LFDs are not perfect but a great tool our population can use to
1. Test frequently at home
2. Safely allow people to not isolate as a contact of a case
3. Allow people out of isolation early safely
~50k positives today on LFDs.
delighted to see Oxford Uni
@ModMedMicro
and
@PHE_uk
report for
@DHSCgovuk
on the preliminary results of Innova lateral flow antigen test for detection of
#COVID19
released and available
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This morning I did an interview on
@r4Today
to highlight how we can use rapid tests for
#covid19
to help find cases. These tests are not a panacea but another tool for us to use. They are not a screening test and if negative people still need to
#HandsFaceSpace
#reducecontacts
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That is wonderfully brilliant. Tweeps best
#handhygiene
video and
#cough
etiquette too - can we get this rolling on repeat - sound on essential -
#infectionprevention
#covid19
Beautiful
#handhygiene
PSA by Iranian comedian Danial Kheirikhah - you definitely want sound on for this 🎶
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PHE now publishes real time data across the UK on cases of confirmed
#COVID19
- future iterations coming
@PHE_uk
@DafyddSiencyns
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People keep saying that SA is over the peak. I think this related to them changing over their reporting systems. (See tweets from 10 dec). Reporting 37.8k cases today.
#omicron
#getvaccinated
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Worrying increasing in
#COVID
cases throughout Europe. Cases have started to rise in the UK over the last 10 days. The immune response wanes so book your COVID booster dose ASAP if you are over 50 here (will open for over 40s next week) - easy to book here
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Key points:
1. iGAS and Scarlet fever Season is earlier than pre-pandemic and higher levels have been seen throughout this year than during the pandemic
2. Rates of infection are 2-3 times higher than seen pre-pandemic at the same time of year
2/8
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Happy Jubilee weekend. Thank you to all the
@UKHSA
teams working as normal to do lab tests, process data, contact trace, provide advice & expertise on infections and hazards, support NHS and LA.
#24
/7
#publichealth
#dedication
👏👏👏
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This is false. Vaccines not only prevent infection. They are even more effective (above 90%) at preventing severe disease, hospitalisation and death. Get vaccinated.
@kallmemeg
@meera_chand
@PHE_uk
@sadizid
@epb41l2
@jcbarret
@erikmvolz
@SMHopkins
@vickichalker1
@PBBlomquist
@elsonmeister
@IsaacATFlorence
@NatalieGroves92
The data shows that while the vaxed are less likely to get it, they're significantly more likely to die when they do.
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So. I am starting to see people’s bios on
@Twitter
saying they are a
#COVID19
expert! Wondering how you can be an expert in 3 months. Expertise in viral infections or related fields and applying knowledge - agree that is what we are all doing. But
#COVID19
?
#porkypies
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Can you deliver to everyone who has had to claim benefits? Key workers are still getting paid! Those who have had to claim universal credits might value a free meal.
Calling all
@NHSuk
workers! 📣💙We’re giving every NHS worker a free meal. Big thanks to our partners
@AmexUK
, The Reuben Foundation,
@Bridgepoint
,
@CocaColaEP
,
@benandjerrysUK
and
@MagnumUK
, for their generous support in making this happen.
#ThankYouNHS
#HereToDeliver
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iGAS is a sepsis syndrome so if your child is dehydrated, is very drowsy or floppy or you are worried (parents know when their child is not themselves) seek medical help. It can be difficult to assess how sick young children are and parent's judgements are important. 4/8
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It’s a great infographic from Ireland 🇮🇪- all the rules on one page.
The Government has decided today that from midnight tonight, the entire county and city of Dublin will be placed on Level 3 of the Framework for Restrictive Measures. Dublin will remain at Level 3 for a period of 3 weeks, until Friday 9 October.
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Today is Nollaig na mBan - Little Christmas or Women’s Christmas as it is known in Ireland. A night for women to rest, recuperate and celebrate with women. To the Mna na hEireann, go raibh maith agaibh and Slainte.
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Principles of monkeypox IPC for UK Management now available
Key points presented by
@UKHSA
DR Cat Houlihan from RIPL and
@uclh
@RCPhysicians
@BASHH_UK
@BritishHIVAssoc
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Great to see so many scientists and healthcare staff being honoured for their COVID-19 work in the Birthday honours.
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As more people vaccinated we will see more deaths in vaccinated individuals. The key is that the vaccine is preventing cases, hospitalisations & deaths. We know that vaccination is preventing hospitalisations by over 90% (95% CI 78-98%). Drugs eg dex, toci & soon mAb will help.
I am still seing a few alarming tweets about double vax and deaths retweeting this from last week 👇
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I’m off to get my first professional (ie not my own bathroom fringe trim) haircut since last September!
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#SIRENstudy
one year anniversary. A blog to highlight what we have learnt from this important research. Thank you all.
@phe_uk
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From June to August, many people were saying that the virus went away by itself, its got milder, nothing to worry about. All of a sudden the virus has changed again. My view.
#smartvirus
No
#peoplebehaviour
Yes
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Loving this celebration of great women involved in COVID data. Great to see
@ukhsa
on the list. And there are loads more…
@meera_chand
who leads variant tech group
@JVRobotham
modelling nosocomial COVID
@stat_sarah
chief ix coronavirus survey
@Susannajd
leading PITCH & many more
The female 'data lads' crunching Covid numbers and keeping us informed through the pandemic
🔴
@KasiaLDelgado
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Tips to prevent Covid-19 transmission in the workplace. When you have finished at a workspace clean the high touch areas before someone else sits there. Be that at a desk, bus drivers changeovers (steering wheel, door handles etc). Also carry hand wipes or alcohol gel and use it!
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Severe disease & death is an extremely rare outcome from GAS , we are highlighting the symptoms to parents & healthcare practitioners to ensure they know the signs.
1. Scarlet fever is a rash syndrome associated with scarlet fever - feels like sandpaper & needs antibiotics 3/8
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From typing of samples sent from NHS labs to
@UKHSA
, we are seeing the same strains that were already in circulation. No evidence of change though deeper analysis ongoing. Rises may be due to reduced immunity from last 3 yrs and high levels of viral co-infections circulating. 7/8
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Penicillin = treatment of choice - GAS remains fully sensitive and using Penicillin mean that children are getting the right treatment while having minimal impact on other bacteria. Pls take a throat swab if you can and if suspect iGAS, needs ED assessment & blood cultures 5/8
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Delighted that
@UKHSA
#techbriefings
are shortlisted for the NHS communications initiative of the year
#COVID19
#MonkeypoxVirus
#Hepatitis
@HSJ_Awards
Brilliantly led by
@meera_chand
, supported by dozens of
@UKHSA
staff, academic & clinical collaborators
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Today is the 1st day of
@UKHSA
- I look forward to continuing the work on COVID19, ensuring the new organisation delivers excellent science, protecting the nation from infectious diseases, chemical, radiation & environmental threats with
@DHSCgovuk
(OHID)
@NHSEngland
@ADPHUK
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And finally
@UKHSA
is a new organisation but it has a long legacy of work with sexual health teams. Our lab staff
@RIPL_Porton
, health protection teams, clinical, guidance, IPC, policy, strategy, data, epidemiology, genomics, admin, finance, commercial are singleminded in focus.
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Very honoured & delighted to be elected - look forward to working with the academy. Many thanks to the many individuals & teams who have supported me & my work over the last 25 years. Particular shout out to
@nihr
@HPRUamr
@ModMedMicro
with directors Alison Holmes & Sarah Walker
Congratulations to our new Fellows announced today 👏
Find out more about these outstanding biomedical and health researchers and see the full list on our website:
#AMSFellows2023
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English Surveillance Programme for Antibiotic Use & Resistance 2019/20 report out today. Fantastic collaborative effort. Thank you all on oversight group and contributors.
#amr
⬆️
#amu
⬇️ especially in GP and dental practice 🙏 but more to do.
#KeepAntibioticsWorking
#EAAD2020
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Just listening to US
#covid19
@BBCr4today
- tiny amount of testing, charging for testing, hospital visits etc. We in Europe and especially in UK - healthcare free to all. So important when dealing with public health emergency
#PHEIC
@NHSEngland
@DHSCgovuk
@PHE_uk
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Great read. Resonates. Hardest 17 months of my working life. Wouldn’t exchange it as have learnt and grown a lot. But “our people” - public health, clinical, scientists, policy - are exhausted and we still have a long road.
#bekind
“Public service is difficult. The past year and a half left many among our ranks exhausted, threatened, saddened and sometimes sidelined.”
Yes, but also extremely rewarding at times, being able to make a difference.
Good read from Anne Schuchat
@CDCgov
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Finally . Pillar 1 and 2 data published for England
@DafyddSiencyns
all downloadable in csv and Json. Thanks
@PHE_uk
data science team
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An important study to understand the effectiveness of antivirals at scale in the UK. If you know people over 50/ over 18 with eligible health conditions then highlight the study. The sooner after test positive the better. The faster people randomised the better.
#panoramic
Have you tested positive for COVID-19 with symptoms starting in the last 5 days? Are you aged 50 or over? Or aged 18+ with an underlying health condition? Then you could be eligible to join the PANORAMIC study looking at new COVID-19 antiviral treatments
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Good infection control is essential - at home, in schools, in healthcare
Wash hands
Cover faces with coughs and sneezes
Stay at home if you can [for GAS recommend that people stay at home until 24 hours after starting antibiotics]
Wear a face covering if you have an infection 8/8
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Massive shout out to colleagues and partners who have rapidly worked together on a system approach to
#PPE
for
#covid19
in uk
@PHE_uk
@NHSEngland
@DHSCgovuk
@AoMRC
@PublicHealthWA
@NHSScotland
@publichealthni
@NHSuk
- we will c/t update with new evidence
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Sunday night
#covid
tests in our house. On a personal note feels important as we mix more to do these tests, find cases and reduce transmission. I know there are many who don’t like the fact that there are rare false positives but a confirmatory PCR test is available for all. 1/2
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Technical briefing 3 for lineage B.1.1.7 VOC202012/01. Great work from the
@PHE_uk
and academic collaborator team
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Thank you - all research teams
@NHSuk
@NHSEngland
Trusts & all the staff participants for coming on board to
#SIREN
@PHE_uk
study - 10k participants which will help us understand whether those with antibodies get fewer/ no
#COVID19
re-infections - Amazing
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So husband developed myalgia and fever yesterday. I stayed in a hotel last night. Today reviewed his timeline and decided his symptoms started about 6 hours after I had left home so I am now in Home Quarantine. Looking forward to Home Working!
#COVID19
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I want to add an additional thanks to organisations supporting us getting the message out in the best way possible
@BASHH_UK
@BritishHIVAssoc
@THTorguk
@Grindr
and all other professionals who are working on Twitter and through their social contacts.
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Worth a read. None of us have answers. Waiting anxiously for data. Every day brings more and only when we have enough data can we call this. Huge uncertainty at present.
Another round-up of London hospital data. TL;DR: still no clear sign of a changed severity profile for omicron, but it remains early days – while omicron is already dominant in London 18-64 cases, it’s probably only a third of recent admissions and even lower for inpatients.
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Well done
@RoyalFreeNHS
for allowing the cameras in so people can see the work that happens. On
#IND2020
Big shout out to my favourite nurse ever.
@BredaAthan
- matron infectious diseases; no nonsense, kindhearted, hardworking and all round fab ☘️ woman.
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Thank you & the
@ukhsa
dashboard team for your amazing service to health, the public, the media, the mathematicians/ modellers. There are so many amazing features on the dashboard… so happy you will continue to support. -of course I want this for every pathogen in the future ;)
Some personal news (a 🧵):
On 4 October 2021, I resigned from my role as the Deputy Head of Software Engineering for Web and Data at
@UKHSA
.
This means that 1 January 2022 will mark my final day in the agency — but *not* on the dashboard, so this is not goodbye.
...[1/10]
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delighted to see Oxford Uni
@ModMedMicro
and
@PHE_uk
report for
@DHSCgovuk
on the preliminary results of Innova lateral flow antigen test for detection of
#COVID19
released and available
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Well done
@kallmemeg
@ukhsa
senior epidemiologist and covid variant tweetorial blog expert.
Nature's 10: An Omicron investigator, a Mars explorer and an AI ethics pioneer are some of the people who helped to shape science in 2021
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Amazingly well summarised as always by
@kallmemeg
- cautious optimism but sheer force of numbers will still bring challenges & half the severity only buys us one doubling time.
#getvaccinated
#FlowbeforeUGo
#keepContactsLow
- thanks team
@ukhsa
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My career choice was driven By HIV and AIDS, the inspirational leadership & teaching of Fiona Mulcahy
@tcddublin
and my first infectious diseases job
@stjamesdublin
#GUIDE
clinic with her & the brilliant
@colm_bergin
. Equity and Equality were at the heart of GUIDE.
#WorldAIDSDay
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If you find new spots, ulcers or blisters, come forward for a test. Our teams will work with you confidentially to ensure close contacts are aware and you are monitored carefully. Thank you all.
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& finally a huge thank you to all the
#SIRENStudy
participants and research teams for their commitment to this study over the last 18 months - 2 weekly PCR, monthly bloods, numerous questionnaires. And to collaborators from
#PITCH
,
#Crick
,
#G2P
,
#Genomicc
@UKHSA
@NIHRresearch
6/6
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Definitely the toughest 5 months of my life. We all need to continue to speak up, listen and support each other. Thanks
@CotterMeaghan
@CrisSuFe
@StrangVirusLab
@devisridhar
@ViralRNA
@DrAngelaH
@ZaniaStamataki
@SMHopkins
@sarahlogan76
@LongleyNicky
@ZulmaCucunuba
It's been a tough 5 months. Though there are prominent women trying to lead, are they (we) being listened to?
@SMHopkins
particularly impressive and has maintained professional diplomacy in a world with increasing bureaucrazy and revolving around meaningless numbers.
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Hope you have all had a great
#IWD21
- so many inspirational female leaders in my life. Thank you all for your support.
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Time to use all those empty hotels and put to good use. London paying for hotel rooms. Let’s use this crisis to help solve homelessness
Stay home and self-isolate. But what if “home” is the street?
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Delighted to see this paper out. Fantastic work led by Laura Shalcross. “Reduced transmission from staff associated with adequate sick pay, minimal use of agency staff, increased staff-to-bed ratio, staff cohorting with either infected/uninfected residents.”
#vivaldicarehome
New in
@LancetLongevity
> Factors associated with
#SARSCoV2
infection and outbreaks in long-term care facilities in
#England
: a national cross-sectional survey
#COVID19
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New evidence released today on the use of
#LFDs
for Covid. Brilliant work done by fantastic colleagues
@PHE_uk
@NHSTestTrace
@ModMedMicro
@UniofOxford
@uniofliverpool
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Another Friday night and thanks to
#nervtag
@benkillingley
@Lisaritchie111
we have the uk
#pandemic
#COVID19
#ipc
guidance live. well done guys.
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Healthcare practitioners - pls notify your local health protection team so that they can detect clusters and provide appropriate support and recommendations where necessary - details available here 6/8
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Saying this gives people the right information to focus efforts and prevent transmission through early recognition. These individuals have always worked with sexual health services to protect each other. This enables them to do this.
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Thanks Meaghan for all the hard work by you, the PHE and academics for working so hard on another great brief. And big call out to
@meera_chand
Right - who is ready for another
@PHE_uk
variant update? 💬
Tonight you get *3 new* publications
1️⃣ India B.1.617.2 TECHNICAL BRIEFING 11
2️⃣ ALL VARIANT DATA UPDATE
3️⃣ INDIA B.1.6172 RISK ASSESSMENT
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Massive team effort
@PHE_uk
; feels strange not to be at the
@NHSuk
coal face
@RoyalFreeNHS
- but I know how hard every
#infection
specialist is working at the moment
#united
to care for
#patients
and
#population
#COVID19
Shout out to
@SMHopkins
and team at PHE for remaining calm under pressure in these extraordinary times (and in the face of a certain amount of provocation from colleagues who are also feeling the pressure). We need to pull together like never before
#COVID19
#coronavirus
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Increasing evidence that this is droplet not aerosol. Therefore preserving ffp3 masks for aerosols generating procedures the appropriate measure.
@SMHopkins
@jim_crawfurd
@PHE_uk
@NHSEngland
@NHSImprovement
@OutbreakJake
@cstewartb
@meera_chand
@Lindajdempster
Why the change to only surgical masks for suspected cases with symptoms when we’ve been telling the population these are not effective enough?
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Huge thanks to the
@ukhsa
epi (led by
@SuperbugKiller
today) and NCRC team for getting out the Omicron daily brief today. . Data lagged & as the proportion of cases due to SGTF above 90% almost everywhere, the dashboard now pretty representative of
#Omicron
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Wow. Thank you
@WomenMedIreland
for the shout out. Standing on the shoulders of female mentors and leaders.
#SundayWiMIN21
Week 29: Dr Susan Hopkins, Healthcare Epidemiologist and Consultant in Infectious Diseases and Microbiology
@PHE_uk
,
@RoyalFreeNHS
and
@ucl
. Member of UK's Scientific Advisory Group for Emergencies (SAGE). Lead
#SIRENstudy
.
Read more:
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