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SCALE@Uni-Frankfurt
@SCALE_Uni_FFM
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We explore the SubCellular Architecture of LifE – from Macromolecules to complex Biological Systems. Partners @goetheuni, @MPIbp, @MPIbrain, @fias_science.
Frankfurt, Germany
Joined January 2022
RT @ShorterLab: Synthetic biomolecular condensates enhance translation from a target mRNA in living cells:
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RT @MolecularCell: RBBP6 anchors pre-mRNA 3′ end processing to nuclear speckles for efficient gene expression https…
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RT @MPIbp: Amazing work @jpkreysing , Maziar Heidarim, Vojtech Zila et al. 🥳 Congratulations on your @CellCellPress paper 🤩 https://t.co/…
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RT @MPIbp: Fresh out of the press! ✨Check out our new paper on the violent entry of the HIV capsid into the nuclear pore — watch it crack t…
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RT @HeilemannLab: We modified our STED🔬to make it more efficient ('smart') to acquire high-resolution data of small and rare objects in a 3…
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RT @WilflingLab: Our latest publication together with the @KraftLabFR, with a nice summary of the findings in this thread 🧵👇🏼
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RT @DormannL: New year, new career opportunity! The @LemkeLab @uni_mainz has 2 Postdoc or PhD student positions in Biophysics or Chemical S…
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The study identifies pressure-dependent fluid flow across NPCs as a key mechanism for rapid nuclear volume adaptation, with broad implications for cellular processes. @goetheuni @MPIbp @imprs_cbp
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RT @hauke_hillen: The peer-reviewed version of our paper on human tRNA 3' processing is now published in @NatureSMB. Many thanks to the rev…
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RT @mahipal_ganji: Check out a preprint from our lab! We've uncovered all possible speed imager sequences for DNA-PAINT. You can now do 10-…
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Beautiful!
Happy New Year, everyone🍀 Excited to see one of my live-cell STED super-resolution microscopy images featured in this year’s @ibidiCells calendar! 🎉 Mitochondria stained by PKMO by @ZhixingChen2 and 610CP-CTX by @AndImaging , recorded on an @Abberior Expert Line.
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RT @lab_nmr: Last action for this year, just in time: Our paper on the evolution of a regulatory RNA element is out! Thank you to the team!…
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RT @MPIbp: Ending 2024 with pride! 🎉 Our director, Gerhard Hummer, was named one of the world’s most cited researchers. 👏✨ His groundbreaki…
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RT @Beck_Laboratory: Difference between diffusion and flow? If you drip paint into a river it locally dissolves by diffusion. It goes downs…
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Introducing cryoTIGER - a computational alternative to denser sampling during tilt series acquisition in cryo-ET. Congratulations to SCALE @SCALE_Uni_FFM members Beata Turonova @MPIbp, Martin Beck @Beck_Laboratory & Gerhard Hummer @HummerLab!
cryoTIGER: Deep-Learning Based Tilt Interpolation Generator for Enhanced Reconstruction in Cryo Electron Tomography
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Huge congratulations to our SCALE @SCALE_Uni_FFM member Bonnie Murphy @_Murphy_Lab for being awarded the Clara Immerwahr Award 2025.
Bonnie Murphy wins Clara Immerwahr Award 2025! 🎉👏💪 Celebrating our faculty member for her outstanding achievements in catalysis research. Her work combines cryo-EM, biochemistry, and molecular techniques to unravel the structure and function of proteins vital to bioenergetics.
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RT @CellCellPress: In the latest issue! How to build the virtual cell with artificial intelligence: Priorities and opportunities https://t.…
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🌟 Huge congrats to @Beck_Laboratory, @FrydmanLab & collaborators on their groundbreaking work on TRiC, the protein-folding machine! Their study maps how TRiC folds proteins in cells, a process key to health & linked to cancer/neurodegeneration, using cryo-electron tomography.👏
Nature research paper: In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor
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