Murphy Lab
@_Murphy_Lab
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Structural and mechanistic study of proteins, especially redox- and metalloproteins
Frankfurt, Germany
Joined September 2021
Happy to share that our work on the FDX2-bound core ISC complex is now published in @NatureComms 🎉 By the way, we are now also on @bluesky! 🦋
🎉 Our latest preprint is now online 👉 Congrats to @RalfSteinhilper who determined #cryoEM structures of the ferredoxin 2-bound core iron-sulfur cluster assembly complex under reducing and turnover conditions at 2 Å resolution. More below! 👇 🧵 1/8
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Our elemental mapping work, combining cryo-EM and EELS to REEL analysis, is now also published on Nature Methods: For a highlight “reel”, see here 👇
Happy to announce that our efforts to establish elemental mapping for cryo-EM ❄️ by EELS 🌈 are now shared on bioRxiv: Congratulations to @zoliviapg and co-authors! But wait - Can we map elements in 3D? 🧵👇 1/6
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Congrats to @MaxYin_211013 and co-authors! Big thanks to X-ray team: Tristan Wagner, Olivier Lemaire and Mélissa Belhamri @MarineMicrobio; computational team: Gerhard Hummer and José Guadalupe Rosas Jiménez @HummerLab; MS team: Anna Shevchenko @mpicbg for the great collaboration!
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Happy to see our study on the structure of 46-kDa Streptococcus pneumoniae NOX out in @NatureSMB! Congratulations to the authors @PABLOSANSEGUND3 and @vicsnorr 🥳 Check it out here (open-access) 👉
Excited to share our preprint: “Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase” in which we obtained a structure of a 46-kDa membrane protein to 2.2 Å resolution without fiducials.
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More research will be needed to reach single-atom sensitivity. In the meantime, we’d be grateful for any feedback and hope you enjoy the read! Also, if you’d like to join the team: We do have an open post-doc position! ^^ 🧵 6/6
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