Excitation of photoactive electron donor–acceptor (EDA) complexes is an effective way to generate radicals. Applications in a catalytic regime typically use catalytic donors. Herein, we report that...

Organocatalyzed atom transfer radical polymerization (O-ATRP) is a light driven method employing organic photoredox catalysts to produce well defined polymers with precise structures. Shown here are...

Olefins are widely available at low costs, which explains the usefulness of developing new methods for their functionalization. Here we report a simple protocol that uses a photoredox catalyst and an...

We are proud to announce Professor Paolo Melchiorre as the 2021 Organic Division open award: Pedler Award winner. Read their full profile and share their achievement here.

Thioesters are important in synthesis, materials science, and biology, and their preparation traditionally relies on the use of disagreeable thiols. Here, we report a thiol-free protocol that...

Register now

We report on a readily available indole thiolate organocatalyst that, upon excitation with light, can activate via single electron reduction a wide variety of typically inert electron-rich substrat...

Reported herein is a visible-light-mediated organocatalytic direct C–H functionalization of toluene derivatives to afford enantioenriched β-benzylated aldehydes from the corresponding enals. The...

The association of an electron-rich substrate with an electron-accepting molecule can generate a new molecular aggregate in the ground state, called an electron donor–acceptor (EDA) complex. Even...

We report a photocatalytic strategy for the chemodivergent radical benzylation of 4-cyanopyridines. The chemistry uses a single photoredox catalyst to generate benzyl radicals upon N–F bond activat...

Nature Communications - In enantioselective catalysis, electron donor–acceptor (EDA) complexes are usually photochemically activated in an intermolecular fashion. Here, the authors report the...

A time to get, and a time to lose electrons: Electron mediators can alleviate limitations associated with the photochemistry of excited-state intermediates, including short lifetimes and low electr...

L’iniziativa, guidata dal professor Paolo Melchiorre e finanziata dallo European Research Council, ha l’obiettivo di usare la fotochimica per sfruttare gli enzimi come catalizzatori biologici e...

For molecules with a singlet ground state, the population of triplet states is mainly possible (a) by direct excitation and subsequent intersystem crossing or (b) by energy transfer from an appropr...

The merger of photoredox catalysis with transition metal catalysis, termed metallaphotoredox catalysis, has become a mainstay in synthetic methodology over the past decade. Metallaphotoredox cataly...

Asymmetric catalysis is a major theme of research in contemporary synthetic organic chemistry. The discovery of general strategies for highly enantioselective photochemical reactions, however, has...