Multiple Sclerosis News Today
@MSNewsToday
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We are a free digital publication dedicated to sharing the latest news, research, and Multiple Sclerosis patient perspectives.
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Over-the-counter clemastine can repair myelin in MS, as evidenced by an MRI method measuring changes in the corpus callosum.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
7
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Ocrevus reduces brain volume loss with relapsing forms of MS to levels similar to those in healthy aging, a small study reports.
#news
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Baclofen, an approved therapy for spasticity in MS patients, could promote myelin repair. Further studies in MS patients are needed to confirm these preclinical findings.
#multiplesclerosis
#msnews
#msawareness
#msresearch
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Shout Out to
@AaronBosterMD
! Dr. Boster is a superstar in the MS community and known for being exceptionally patient-oriented and skilled at simplifying complex MS topics. We're thrilled to profile Dr. Boster and his amazing work on our Twitter today.
5
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Many MS symptoms can be hard to describe, especially fatigue. How do you best characterize this complex symptom?
#multiplesclerosis
#msnews
#msawareness
#mscommunity
27
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Fatigue, a feeling of mental or physical exhaustion that limits an ability to go about daily life, is one of the most common symptoms of MS.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
#mstreatment
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Has MS changed the way you relate to people? Tell us in the comment section below:
#multiplesclerosis
#msnews
#msawareness
#msresearch
43
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The second SPMS patient given experimental foralumab nasal spray showed significant functional improvements after six months and is now able to walk 100 meters without a cane or need for rest.
#multiplesclerosis
#msnews
#msawareness
#msresearch
2
16
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Repairing lost myelin is seen by many as a “holy grail” quest for disease treatment. Researchers are now closer with a new clinical trial that is testing whether an antihistamine in combination with a diabetes medication might promote remyelination.
#MSnews
4
18
60
Over-the-counter clemastine can repair myelin in MS, as evidenced by an MRI method measuring changes in the corpus callosum.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
4
13
60
FDA Approves Ocrevus as 1st MS Treatment for Both Relapsing and Primary Progressive Forms
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Treatment with polysialic acid increased myelin repair in a cell model of MS by altering the activity of brain immune cells called microglia, a study finds.
#news
0
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While more than 20 MS treatments work to reduce inflammation, no treatment has yet been proven to promote myelin repair. That may soon change.
#MS
#MultipleSclerosis
#MSResearch
#MSNews
1
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About three-quarters of those with MS experience symptom worsening as a result of heat. How do you manage?
#multiplesclerosis
#msnews
#msawareness
#mscommunity
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Through the activation of two types of nervous system support cells, XPro1595 may promote myelin restoration that could help MS patients.
#news
3
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Treatment with estriol, a hormone that's made during pregnancy, reduced disease severity and promoted myelin repair in a mouse model of MS.
#news
3
10
51
Caffeine tablets, which equal about two cups of brewed coffee a day, may help people with MS maintain their balance and move more easily.
#news
3
7
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Certain immune cells are able to take on healing abilities allowing them to repair damaged nerve fibers, a possible strategy for treating MS.
#news
1
11
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Experimental therapy NVG-291 has been shown to be well tolerated in an ongoing study. It is expected to help promote nervous system repair, including restoration of the myelin sheath that’s damaged in MS.
#multiplesclerosis
#msnews
#msawareness
#msresearch
6
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Janssen has obtained rights to develop PIPE-307, a potential oral therapy that aims to restore myelin sheath. A U.S. clinical trial for RRMS patients is expected.
#multiplesclerosis
#msnews
#msawareness
#msresearch
1
10
46
In MS, T-cells drive the body’s mistaken immune system attack on healthy parts of the nervous system. Researchers have now identified four new brain proteins targeted by these cells, which could result in new, more specific treatments.
#multiplesclerosis
0
15
48
Diet has emerged as an important factor that may impact MS progression, whether by modulation of the immune system or changes to metabolism.
#multiplesclerosis
#msnews
#msawareness
#msresearch
4
15
45
A new study reveals that in MS, damage to the myelin sheath causes increased levels of VLCFAs, which are converted into an inflammation-driving molecule called S1P, presenting potential treatment options.
#multiplesclerosis
#msnews
#msawareness
#msresearch
1
16
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The new system that can use MRI to measure myelin in brain tissue anticipates the approval of remyelinating drugs in the coming years.
#news
1
10
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Mavenclad showed sustained benefits for up to 15 years in MS patients, with over half not needing further DMTs and more remaining relapse-free, according to trial data.
#multiplesclerosis
#msnews
#msawareness
#msresearch
1
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Stem cell therapy was better than Gilenya and Tysabri, but not Ocrevus, at reducing disability for people with aggressive RRMS, an analysis suggests.
#news
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What are your biggest challenges in living with MS? Tell us in the comments below:
#multiplesclerosis
#msnews
#msawareness
#msresearch
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The Octopus clinical trial is testing multiple therapies at the same time to accelerate the development of treatments for progressive MS. The trial currently is recruiting participants in the U.K.
#multiplesclerosis
#msnews
#msresearch
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The over-the-counter antihistamine clemastine has shown an ability to repair myelin, as detected using a noninvasive MRI approach.
#news
3
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Immune response against cow milk with multiple sclerosis likey due to similarities between milk proteins and central nervous system proteins.
#news
1
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While more than 20 MS treatments work to reduce inflammation, no treatment has yet been proven to promote myelin repair. That may soon change.
#MS
#MultipleSclerosis
#MSResearch
#MSNews
1
10
44
Scientists have published a new framework to help guide research that seeks to understand how exercise benefits people with MS.
#news
1
9
42
Well-meaning questions or advice can still seem harsh. What sentiments would you prefer that people keep to themselves? Tell us in the comment section below:
#multiplesclerosis
#msnews
#msawareness
#msresearch
57
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43
Protein Mfsd2a deficiency was found to play a key role in myelin sheath production. Researchers now plan to conduct studies to see if dietary omega-3 can help remyelination.
#multiplesclerosis
#msnews
#msawareness
#msresearch
1
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42
Treatment with estriol, a hormone that's made during pregnancy, reduced disease severity and promoted myelin repair in a mouse model of MS.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
#msresearch
2
4
42
New study findings provide a proof of concept for how gut bacteria activate immune cells that trigger the inflammatory attack that causes MS.
#news
2
11
41
A protein in the COVID-19 virus is similar to proteins targeted by the immune system in MS, which may explain how COVID-19 could trigger MS-like diseases.
#multiplesclerosis
#msnews
#msawareness
#msresearch
4
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Researchers believe a single infusion of the CAR T-cell therapy may provide lasting disease control for those with progressive MS. Learn more:
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
0
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After nine years on Ocrevus, nearly half of those with relapsing MS who were treated early showed no evidence of disease activity.
#multiplesclerosis
#msnews
#msawareness
#msresearch
3
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Pipeline is working with Janssen to advance PIPE-307, a myelin-restoring oral therapy expected to enter a clinical trial in MS patients.
#news
4
9
39
Heat sensitivity is a real concern for MS patients. What helps you stay cool?
#MSAwareness
#ThisIsMS
#MSLife
#MSCommunity
#MSSupport
13
5
39
A
@mssociety
grant will help advance development of an experimental treatment designed to promote myelin repair. Read about it:
#MS
#MultipleSclerosis
#MSResearch
#MSNews
7
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41
Explore why scientists say resistance training may be especially beneficial for middle-aged and older MS patients:
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSAndExercise
2
9
41
Does coffee affect your MS symptoms in any way? If so, how? Tell us in the comment section below:
#multiplesclerosis
#msnews
#msawareness
#msresearch
23
6
39
Study in 234 MS patients with COVID-19 found a significant quickening in neurological disability (EDSS score changes) after a positive test.
#multiplesclerosis
#msnews
#msawareness
#msresearch
7
15
38
An MRI study provides the first evidence that an over-the-counter antihistamine may be able to repair myelin.
#multiplesclerosis
#msnews
#msresearch
#MRIstudy
0
9
39
Neurologists considered effective management of primary progressive MS and secondary progressive MS as the greatest unmet medical need.
#news
5
6
39
Supplements of coconut oil and green tea are linked to MS functional improvements, possibly by reducing triglycerides, a study suggests.
#ms
#multiplesclerosis
#msresearch
#msnews
1
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39
MS is known to damage myelin. Encouragingly, a new medication aimed at restoring myelin appears to be safe and well tolerated in healthy adults.
#multiplesclerosis
#msnews
#msawareness
#mstreatment
1
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An open-label Phase 1 trial will soon evaluate the clinical performance of a therapy designed to reset patients’ immune systems.
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
#ClinicalTrial
0
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38
New trial data indicate that most patients with up to five years of treatment with Kesimpta show no evidence of disease activity.
#multiplesclerosis
#msnews
#msawareness
#msresearch
2
7
38
Scientists in Iran have discovered a new way to convert astrocytes into oligodendrocytes, the cells that make and repair myelin in the brain.
#MS
#MultipleSclerosis
#MSResearch
#MSNews
3
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38
Many people with MS experience pain, though the type and severity vary. We cover all things pain-related in our resource on the topic.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
1
8
37
The
@mssociety
award will speed up development of a treatment that “could constitute a paradigm shift for the benefit of people with MS.”
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
3
6
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Did you know more than 10 potential treatments for progressive MS are currently in Phase 3 trials? See how the field has changed in recent years:
#ms
#multiplesclerosis
#msresearch
#msnews
#mstreatment
3
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Have you ever used medical cannabis to manage your MS symptoms? Has it helped? Let us know in the comments below:
#multiplesclerosis
#msnews
#msawareness
#msresearch
20
5
36
A new immune cell strategy in which microparticles activate Tregs has shown promise at reversing disease in a preclinical model.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
3
9
37
Benjamin Hofmeister acknowledges the difficulty in explaining MS fatigue, a common but variable symptom that can completely disrupt patients' lives.
#multiplesclerosis
#msnews
#msawareness
#msresearch
3
9
37
Over-the-counter clemastine can repair myelin in MS, as evidenced by an MRI method measuring changes in the corpus callosum.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
0
6
37
Explore how scientists converted star-shaped brain cells that support nerve function into cells that make and repair myelin in the brain:
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
0
11
35
A new treatment approach could prevent abnormal immune cells from reaching the brain and spinal cord and causing nerve cell damage — and it might do so without the side effects of current MS therapies.
#multiplesclerosis
#msnews
#msawareness
#msresearch
3
10
35
Vitamin D supplementation reduced the signs of progressive disease in a rat model of progressive multiple sclerosis (MS), a study showed.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
1
6
36
EBViously announced that it has developed a candidate vaccine against the Epstein-Barr virus. The company plans to move it to clinical trials in 2024 with the first test aimed at preventing mononucleosis.
#multiplesclerosis
#msnews
#msresearch
0
6
36
Welcome to Day 1 of the ACTRIMS Forum 2023! The MS News Today team is on-site and will be reporting live throughout the conference. We’ve got a lot of great stuff coming up. Stay tuned!
#actrims2023
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Research into the benefits of cannabis for MS is still ongoing. We break down what we do know in this dedicated resource on the topic:
#msawareness
#thisisms
#mslife
#mscommunity
#mssupport
8
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3
34
A small molecule triggered myelin sheath repair in a mouse model of MS, improving motor function and nerve cell communication, per a study.
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
0
5
33
Some patients report cannabis helping with MS-related pain and spasticity. What effects have you noticed?
#msawareness
#thisisms
#mslife
#mscommunity
#mssupport
20
2
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In MS, resistance training and aerobic exercise may be better than other exercise types at improving muscle, heart, and lung fitness.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
3
9
34
In MS, active lesions on MRI scans reflect inflammation, but there may be disease progression even when scans don’t show new activity.
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
2
5
32
In two clinical trials, a cannabis oral spray demonstrated potential to significantly alleviate MS muscle stiffness and spasms.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
1
12
34
Accepting an MS diagnosis is hard. Supporting loved ones through it can be equally as difficult. Consider these strategies:
#multiplesclerosis
#msnews
#msawareness
#mscommunity
1
7
34
EBViously reported having developed a vaccine against the Epstein-Barr virus and plans to test it in preventing mononucleosis in 2024.
#news
0
4
34
MS lesions start off as a core of a few inflammatory immune cells, and damage spreads outward from these cells, a new mapping study shows.
#news
0
9
33
A new study has found that drinking black and green tea, coffee, and nonalcoholic beer may reduce the risk of developing MS, while carbonated drinks, milk, and fruit juices may increase it.
#multiplesclerosis
#msnews
#msawareness
#msresearch
4
7
34
One study examining the impacts of stress on MS found that childhood and adulthood stressors contribute to disability levels.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
#msresearch
2
9
34
In MS, disability worsening independent of relapses often occurs alongside greater atrophy in the spinal cord and inflammation, a study found.
#news
2
6
32
Do MS patients experience fatigue the same way healthy people do? Read about researchers’ new insights here:
#multiplesclerosis
#msresearch
#msnews
#chronicfatigue
0
4
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Ben Hofmeister explains why he sometimes feels “half-sick” and “half-abled” — and why this in- between space is so frustrating.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
2
12
33
Ben Hofmeister shares the frustration he feels trying to explain MS fatigue but also understand it himself.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
1
11
33
Researchers note the compound had “a stunning effect on rescuing myelin and motor function in the lab models.” See how here:
#ms
#multiplesclerosis
#msresearch
#msnews
#mstreatment
1
5
27
Researchers from Johns Hopkins School of Medicine developed what they call “a promising platform for treatment of autoimmune diseases.”
#multiplesclerosis
#msnews
#msawareness
#mscommunity
0
5
32
Check out Damian Washington's favorite MS Life Hacks:
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Both are oral treatments whose pharmacological properties make them well suited as once-daily drugs. Learn how they work here:
#MSResearch
#MSNews
#MSTreatment
#ACTRIMS
#ACTRIMS2024
0
4
31
This columnist and MS patient couldn’t find a word for someone who falsifies being well, so he created one. He shares it here:
#msawareness
#thisisms
#mslife
#mscommunity
#mssupport
2
9
30
With MS, diet is important. Saturated fat intake has been linked to a risk of MS relapses and disease progression. We explain this further in our new resource on diet and MS.
#multiplesclerosis
#msnews
#msawareness
#msresearch
2
3
32
A four-week trial of nabiximols, a spray of cannabis compounds, worked to ease spasticity and improve arm and hand function in MS patients.
#multiplesclerosis
#msnews
#msawareness
#msresearch
2
7
31
New findings from Phase 2 study data reinforce the therapy’s potential to slow or halt MS disease progression. Learn more:
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
1
7
32
One study found increased neurofilament light chain protein among MS patients with no evidence of recent relapse activity or lesions.
#multiplesclerosis
#msnews
#msawareness
#mscommunity
1
4
31
The formulation is given twice a year as a 10-minute injection but appears to deliver the same clinical benefit as longer infusions.
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
5
5
31
Disability progression in people with MS reduces their life quality and ability to work, and increases healthcare costs, a study in Germany finds.
#news
13
8
31
In a preclinical study, Baclofen, an approved therapy for spasticity in MS, showed potential as a possible therapeutic approach to stimulate myelin repair.
#multiplesclerosis
#msnews
#msawareness
#msresearch
1
11
31
The device, about the size of an oral capsule, is implanted in the neck through a small incision done during an outpatient procedure.
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
0
4
31
Use of foralumab nasal spray was found to reduce fatigue levels in seven of 10 patients with nonactive SPMS in an expanded access program.
#news
0
4
31
The Neural Sleeve can help counter foot drop in MS, with studies showing its use resulted in an average 143% reduction.
#ms
#multiplesclerosis
#msresearch
#msnews
#mstreatment
1
4
31
Use of the nasal spray also led to stabilization or improvement in other clinical measures in all patients.
#MS
#MultipleSclerosis
#MSResearch
#MSNews
#MSTreatment
0
6
31
Lucid-MS, an oral treatment candidate, aims to prevent — or even repair — myelin damage without interfering with the immune system.
#multiplesclerosis
#msresearch
#mstreatment
#msnews
0
6
31
A candidate vaccine against the Epstein-Barr virus is set for clinical trials in 2024, with the first test targeting mononucleosis prevention.
#multiplesclerosis
#msnews
#msresearch
3
7
31