Isaac Garcia Bosch
@IsaacGB9
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Chemist. Associate Professor at CMU (Pittsburgh)
Pittsburgh, PA
Joined April 2012
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It’s finally official! Thrilled to share that our lab has been awarded with an R35 ESI MIRA from the
@NIH
@NIGMS
: 5 years of funding (1.7M!!!) to develop functional synthetic models of Cu-dependent monooxygenases!
#Yes_Cu_can
#NIHfunded
@SMU
@SMU_Chemistry
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Our group has been awarded with the NSF CAREER! Research on Cu catalysis and cool bilingual outreach activities for youngsters in TX. Thanks to present and past grad and undergrad students. You guys make my job easy!
@NSF
@SMU_Chemistry
@SMU
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JACS paper accepted! Great way to finish a fantastic week. Congrats
@Tong_Wu_1997
! And thanks to our collaborators at Cornell,
@LancasterLabCU
! Will post the link soon...
#Yes_Cu_Can
#CuOH
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Today my 1st grad student (Rachel) obtained her PhD! I am really proud of you! Dr. Trammell is a super star: has published numerous papers, mentored grad and undergrad students and has been involved in many outreach activities. Can't wait to see what is next in your career! 🍾
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Stay tuned because this one is going to blow your mind!!! 🤯
@Tong_Wu_1997
@KhashayarRajabi
@AnkitaPuri20
@Marcel_Swart
@CMU_Chem
#Yes_Cu_can
#4protons4electrons
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I brought my daughter to a GRC conference this year. Very surprised to see that she is the only child attending. I guess people are a little shocked seeing a male PI bringing children to a conference. Crazy. 🤷🏻♂️
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We are hiring a postdoc! Come and work with us in our NIH-funded project "Functional Synthetic Models oF Cu-dependent Monooxygenases". Send me a DM or email at igarciabosch
@smu
.edu. Start date: ASAP!
@SMU_Chemistry
#Yes_Cu_can
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Richel (high-school student in front) teaching Rama (undergrad) how to run a Cu hydroxylation. Keep an eye out for Richel's applications to college, she is a very talented and smart individual with a bright future in front of her. I'm so proud of my lab! 😊
#Yes_Cu_Can
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Our latest paper on controlling the geometry of metal complexes via jntramolecular H-bonding interactions is finally out! >2years of hard work by
@AnkitaPuri20
and the rest of the team. Enjoy!!! 😉
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And here it is! A 4H+/4e– Electron-Coupled-Proton Buffer Based on a Mononuclear Cu Complex: SCXRD, spectroscopy, DFT, uncoupled substrate dehydrogenation, BDFE analysis, mechanism and more. Enjoy!!!
@CmuScience
@CMU_Chem
#Yes_Cu_Can
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Paper alert! After >2 years of hard work, we report the regioselective hydroxylation of unsymmetrical ketones using DGs, Cu and H2O2. Work led by Shuming Zhang (soon to be Dr. and looking for a PD position) and many others (including 5 UGs), $$$ by
@NIH
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I'm happy to share that our lab has been awarded (again) with the
#WelchFoundation
research grant! 3 more years of Cu, redox-active ligands and H-bonding! Thanks to all of my amazing undergraduate and graduate students who made this possible!
#Yes_Cu_can
@SMUChemistry
🍾🎉😊
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This paper made my day! Organic chemists using our Cu-promoted hydroxylation method!!!! 😍
#Yes_Cu_can
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I received my green card today!!! Visca Catalunya i visca els U.S.A.!!!! PS: got some figs from the garden too... pretty sweet day!!! 😉
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Prof. Hartwig is the recipient of the Third Annual Edward R. Biehl Lectureship from
@SMU_Chemistry
. Hartwig will be giving a "virtual" seminar on Tuesday 15th (3pm CST) entitled "Selective Catalytic Functionalization of C-H bonds". If you want to attend (ZOOM), please send a DM!
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Tonight we said goodbye to Dr. Zhang, the 4th PhD student from our lab. Shuming work focused on Cu-directed C-H hydroxylation reactions and his last paper is one of the most downloaded articles this year in JOC. Congrats Shuming, we are very proud of you!
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Today I received the best news a PI can get: Rachel Trammell (4th year PhD student in our lab) was awarded with the SMU Dean's Dissertation Fellowship 2020-2021.
@SMU
@SMU_Chemistry
I'm very very happy because Rachel is a very talented chemist and a great person. 😊
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I'm "visiting" Texas A&M this week. Weirdly, when I think about chemistry in Texas, it is still the department that first comes to my mind (Darensbourg, Cotton, Barton...). I'm so nervous! 😅 Thanks for the invitation
@Powers_Lab
!!!
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After two hours of gen chem, I guess I needed a break... ⚽️⚽️⚽️
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More news from our lab! In this EJIC paper, we describe an unusual Cu complex capable of binding H2O and H2O2 reversibly, which might help explaining the peroxidase and peroxygenase chemistry in LPMOs. Thanks
@NIH
for funding our Cu/H2O2 research!
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I taught the inorganic chemistry course in person this week for the first time since Fall 2019... I forgot how much I love it! 😊
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Today I recorded the lectures for my advanced inorganic class for next week. Electronic spectra of metal complexes. I love Tanabe-Sugano diagrams! :)
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The REU Chemistry Summer Research Program at CMU is finally here! Fully funded positions to work in awesome labs (including ours! 😊), please spread the word and apply!!!
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Happy to announce that the Garcia-Bosch lab has been awarded with an NIH grant to study bioinspired Cu-promoted hydroxylations. Thanks to the entire lab (present and past graduate and undergraduate students) for all of your hard work! 👏✌️🍾💪
@SMU_Chemistry
@SMU
#yes_Cu_can
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Rachel's paper on Cu-directed hydroxylation of sp2 and sp3 C-H bonds is finally out! Lots of oxidations, inorganic synthesis, spectroscopy, kinetics and DFT (with
@Marcel_Swart
) that you can read in
@InorgChem
.
#Yes_Cu_can
@SMU_Chemistry
🍾✌️🎉
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The great Ken Karlin is visiting our department today! We are very excited to hear about the recent finidings from the
@KarlinLab
!!!! Cu, Cu and more Cu (and maybe some heme...)!!!
@SMU_Chemistry
@SMUDedman
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😊
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Congratulations Dr. Wu!!!!
@Tong_Wu_1997
is the third PhD from our lab. We are extremely proud of you! Time to celebrate!!!! 🍾🍾🍾
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Tenure-tour continues! After visiting U. of Girona and ICIQ this summer and giving two invited talks at ACS in San Diego, I'll be travelling to U. of Mississippi (Thursday), U. of Memphis (Friday), Duke (next Wed.) and NCSU (next Thu.). East coast November!
#Yes_Cu_Can_Tour
😃✈️
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This weekend I drove from Dallas to Pittsburgh. Is it weird that I thought I was following the U.S. Cu route? Memphis (
@doktor_clark
), Cincinnati (
@WeiLiuLab
), Columbus (
@ZhangLabOSU
), West Virginia (
@Hoover_Lab
) and Pittsburgh (
@MatyPolymerLab
)! 😊
#Yes_Cu_can
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Should I include this in my tenure package? 🤔 PS: I would like to thank my collaborator and artistic director Èlia Garcia-Bosch. 😊
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My very talented graduate student Khash has been awarded with the ACS-DIC Student Travel Award to support his trip to the Fall 2019 ACS Meeting in San Diego. Congratulations
@RajabiKhashayar
!!!
@SMU_Chemistry
#HBonding
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Today I posted the firsts videos of my gen chem online lectures. I offered extrapoints to students to watch the video today and send me their feedback via email. A) Around 50% send me an email; B) very useful comments ; C) they are prepared for this! 💪 I love them! 😊
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Our JACS paper in now online! Congrats to my amazing grad student
@RajabiKhashayar
and our three undergrads (Yousef, Umy, Sidney and Dylan). Many thanks to Max (JHU, X-ray) and
@Marcel_Swart
(
@IQCCUdG
, DFT)!!!
#Hbonding
#Yes_Cu_can
#Im_so_fxxxing_proud
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New paper online (J. Coord. Chem., Emerging Leader Special Issue)! We report a detailed analysis of the intramolecular H-bonding interactions in Cu complexes (more than 20 crystal structures!). Good job
@RajabiKhashayar
!
#Yes_Cu_Can
@SMU_Chemistry
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I really enjoyed the group dinner tonight. I love this people! 😊
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I had so much fun visiting
@DukeChemistry
today! Such an amazing department with such an awesome chair! Lots of Cu, redox-active peptides (maybe? 😉) and cool organic transformations. Plus great traditional NC BBQ for dinner!
@FranzLabDuke
@roizengroup
#Yes_Cu_can_tour
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Watching my 10-days old daughter and working on our next paper on Cu hydroxylations. Feels like heaven.
#PI_life
#newdad
#sleepfor5moreminutes
Èliaplease
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Come and be my colleague at
@SMU_Chemistry
! We are hiring tenure track assistant professor (all experimental areas)! I would love to see applications from individuals with identities historically minoritized in the sciences! Please RT!
@Chemjobber
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I had a lot of fun visiting Auburn today! Definitely one of the best chem departments in the south! I learned about catalysis, electrochemistry and Cu C-H activation. And we established new collaborations! I couldn't be happier! Also, breakfast, lunch and dinner were awesome!
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First time I put my daughter to sleep by myself (Gina enjoying an Ali Wong live show tonight with some friends)! Èlia took a bath, ate half a bottle of milk and fell asleep right away. Feeling proud of myslef! 💪👼🏻👨👧💃🏻
#homealone
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I canceled my Tuesday class. I'll be in my office for office hours. So please guys, vote!!! Do it for me (I wish I could vote in a free Catalonia) and for my 2 months old Texan daughter!!!
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On my way to
#ACSSanDiego
! I'll be presenting some of my group's research on H-bonding tomorrow afternoon in the Emerging Research in Molecular Synthesis symposium. 😊
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I visited UAH yesterday and I'm giving a talk tomorrow at Sewanee, so today we decided to explore Huntsville with Gina and Èlia.
#PI_life
#tenuretour
#Yes_Cu_can
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Richel, a high school student doing research with us at SMU, has won the science fair in Duncanville presenting some cool copper complexes that she synthesized in the lab. And now she is headed to the regionals! We are so proud of you! 😊
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Thanks
@ReginaBaglia
!
@Tong_Wu_1997
and
@KhashayarRajabi
did an amazing job: a mononuclear CuOH complex (very rare species) in three (!!!) oxidation states. Synthesis, spectroscopy, reactivity, lots of kinetics... What else do you need in life? 😉
Congrats,
@IsaacGB9
and lab! 🥳 See below if you are up for some *radical* copper chemistry this morning:
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And many many many thanks to my own special editors: It’s ALL for you and ALL because of you!
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I had a blast at ICIQ today!!! They do beautiful chemistry and Tarragona is a wonderful catalan city! The dinner with students was awesome (great seafood) and the lunch with
@JulioLloret
was the best meal I had in a while! Now we will explore the city with Èlia and
@ReginaBaglia
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Grantwriting before visiting
@DukeChemistry
tomorrow. I found a nice brewery close to the hotel. I love NC! 😊
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After watching Frozen for the 300th time, Èlia decided to spice things up and watch it upside down. And we've only been confined for 5 days. 🙄
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Watch out
@ReginaBaglia
, we have a new editor in the family!!! Èlia was clearly not convinced about this figure so I changed it! I hope the reviewers like it now! 😉
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The only way to go back to "normal" asap (I assume Spring 2021): 1) lockdown now!; 2) impose mask requirements; 3) universal healthcare; 4) universal unemployment checks; 5) support companies that implement working from home.
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We are not attending
@4Pcet
but we talked about PCET during Tong's thesis defense... Some do 1, some do 2, but Tong does 4 protons and 4 electrons at a time... 😉
#Yes_Cu_can
@Tong_Wu_1997
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Paper submitted!!!! 🍾🍾🍾💪
#Cu
I'm very happy for the very talented
@Tong_Wu_1997
!!! Good job Tong!! 👏👏👏
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Last night, Èlia asked for the second "gata" to go to bed. I told her that since she has two "gates", we should name them. She told us that one should be named "PINK" and the other one "ROSA". And that is the smartest thing I heard this year.
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CHEMICAL REVIEWS ACCEPTED!!!! 🍾🎉 🍾🎉 Stay tuned chemtweeps!!!!
#Yes_Cu_can
#whataNovember
@SMU_Chemistry
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Having coffee with Èlia in the backyard. We saw a hawk, a squirrel (that got too close to the hawk), a cardinal and many other birds I could not name. We like it in here... 😊
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Congrats grad student
@GoswamiSunipa
and undergrads Jimin, Sheng, Karan, Daniel, Yi Lin and Emma for the Departmental awards!!! 🍾🍾🍾
@CMU_Chem
@CmuScience
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Cool!!! We are working on the MO diagram for this molecule in my AIC class this week (symmetry of the AO of the metal, LCAO for the ligands, etc.) Published just in time to change my notes for this afternoon... 😊
Check out the latest
@InorgChem
article:
@Jules_Oppenheim
and first-time author Jayce Miller et al. revisit the electronic structure of [Ni(CN)4]2-, which has been debated since the 60's.
#ChemTwitter
#TeamGray
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It's finally here!!! Our Chemical Reviews on Cu is online. Check it out:
#Yes_Cu_Can
#triplewordscore
@SMU
@ACSChemRev
@SMU_Chemistry
Congrats Rachel and
@RajabiKhashayar
!!!
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Rachel Trammell, amazing PhD student and expert in Cu-promoted hydroxylations, is featured by SMU in this article. Check it out!
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I had the chance to work for a WHOLE hour on a manuscript we are writing with
@Tong_Wu_1997
and
@LancasterLabCU
! Oh man, I love my job!!! Thanks
@ReginaBaglia
for taking care of È! I'm so excited about this paper!!!
#weloveCu
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I can't belive it's been almost a month since my second grad student,
@KhashayarRajabi
defended his thesis!!! We are very proud of him and wondering what he will be doing next (stay tunned...😉)! We miss you here in Pittsburgh!
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To summarize my 2018, I only need 4 letters: ÈLIA! Per resumir el meu 2018 només necessito 4 lletres: Èlia! 😍👼🏻👨👩👧
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First PT appointment after my knee surgery 9 days ago... Let's do this!!! 💪💪💪
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Hey twitter friends. Do you know of any case of tenure denial following the 2008 economic crisis? Asking for many friends...
#chemtwitter
#AcademicTwitter
@chemjobber
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Congratulations
@francesarnold
for the
#ChemNobel
award. Glad to see some bioinorganic chemistry!!! And also, finally a woman! 🍾🍾🍾
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Working from home this week (it's hard!!!)... but I feel lucky!
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Healthy family, JACS, Chem Rev and an amazing research group! Tonight we celebrate. 🍾👨👩👧📝
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Hey chemtweeps, you can find our
@J_A_C_S
paper as ASAP online. Congratulations
@RajabiKhashayar
!!!! 👍👍👍
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Not at the
#ACSFall2023
but 3 of our UG students (Daniel, Karan, Sheng) and 2 grad students (Sunipa, Shuming) are presenting posters and oral communications. If you have a chance, go and check it out!!!
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If you need to buy a new glovebox be aware: We sent the purchase order ten days ago and I have been told by the company (that will remain nameless) it won't be delivered until mid February! 😔
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I think about this song every time I propose a mechanism... 😊
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