Frances Arnold
@francesarnold
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Innovation by evolution, Linus Pauling Professor at Caltech, Nobel Prize in Chemistry (I am an engineer of the biological world)
Caltech
Joined June 2010
We are thrilled to present a new #enzyme to the world, the first shown to break the man-made carbon-silicon bonds in #siloxanes, which are persistent in the environment.
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I could not be happier about serving at this time and for this President. #ScienceisBack.
Science will always be at the forefront of my administration — and these world-renowned scientists will ensure everything we do is grounded in science, facts, and the truth.
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Thank you everyone! I love this supportive community. I'm stunned, and now I just have to get home from Dallas. .
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It is painful to admit, but important to do so. I apologize to all. I was a bit busy when this was submitted, and did not do my job well.
For my first work-related tweet of 2020, I am totally bummed to announce that we have retracted last year's paper on enzymatic synthesis of beta-lactams. The work has not been reproducible.
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#finally caught up with @CarolynBertozzi and Jennifer @doudna_lab #nobelweek #chemnobelles @NobelPrize
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For my first work-related tweet of 2020, I am totally bummed to announce that we have retracted last year's paper on enzymatic synthesis of beta-lactams. The work has not been reproducible.
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You might be interested to know that the binary code on the stage writes out "truth not lies." just ignore the person blocking it. #ScienceisBack
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How much fun is this? I get to play myself on The Big Bang Theory!.
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Four American #NobelLaureates gather before the #NobelCeremony. #NobelWeek @doudna_lab Andrea Ghez @CarolynBertozzi
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I cannot wait to see science back at the heart of decision making. So important for our Nation. #scienceisback with @eric_lander and @maria_zuber @https://buildbackbetter.gov/press-releases/president-elect-biden-announces-key-members-of-his-white-house-science-team/.
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Look how many University of #California #NobelLaureates I was able to gather in just 2 minutes. A great public university and a national treasure @UC_Berkeley @UCLA. #NobelWeek
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This is how I am listening to your zoom presentations these days. Some joys amidst the sadness. #grandmother
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Last week in London I added my signature to the great @RoyalSociety book, signed by #IsaacNewton and #CharlesDarwin (see photo), among many others. Grateful to be elected a foreign member.
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Wonderful day with Catherine Reynolds and @doudna_lab Jennifer Doudna (and Albert Einstein) in 2019. #NobelPrize @NobelPrize.
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This little guy, James Bailey, showed up in the middle of #COVID, and I am a happy #grandmother! His father got back from #Mars2020 launch of @NASAPersevere just in time!
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On my way to @NobelPrize festivities! Looking forward to celebrating #science and some wonderful friends. I’ve got everything in a carryon this time, takin’ no chances w travel demons…
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For those of us who were listening to our black colleagues last week #BLM, the timing of the Hudlicky essay in @angew_chem could not have been worse. How such a poorly written and poorly reasoned piece have been reviewed and published there is beyond me. TY @Joseph_DeSimone.
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#DonnaStrickland and I show off our (chocolate) #Nobel medals at the Nobel Foundation reception at the end of our magical week in #Stockholm for the @NobelPrize.
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Arriving @Caltech on October 3 after the @NobelPrize announcement! My sons and students were there to meet me.
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I'm looking for new team members (postdoc) to explore #chemistry not known in #biology with #directedevolution. If you are interested in #greenchemistry done biologically, read our publications & apply if Caltech and working at cutting edge is for you! #enzymes #biocatalysis.
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We need more women in #science and #technology, because there's so much to do, including making it safe for people. Plus, solving problems is fun! .
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What an honor to be chosen for the Priestley Medal. #Enzymes are the best chemists, of course, but the Priestley medalists are no slouches. and include many of my colleagues @CaltechCCE. Thank you!.
Congrats to #NobelLaureate @francesarnold, recipient of the 2025 Priestley Medal, the highest honor awarded by ACS which recognizes an individual for distinguished service to #chemistry. #ChemTwitter #Awards #NobelPrize
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#Chemists in Stockholm! @GRCPres came to see all the fabulous women scientists the @GordonConf have celebrated over the years.
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Life goal.
The only scientist to win both the Nobel and IgNobel prizes (for amazing science/very silly science respectively) is Andre Geim. He won the Nobel prize in 2010 for the properties of super-material graphene. He won his IgNobel in 2000 for making a frog levitate with magnetism.
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Please forgive my five-years-old flirt with forming an armed militia.
"No one knew what to do with a smart little girl in the 1960s.". Aged five @francesarnold spent as much time as she could outdoors going on adventures. Today Arnold is a celebrated engineer, who was awarded the Nobel Prize for the directed evolution of enzymes.
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Pope Francis gave me this beautiful necklace, as a new member of the Pontifical Academy of Sciences. #gratitude, #hope, #scienceforpeace.
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Yes this is Bob Langer and Steven Tyler @IamStevenT of @Aerosmith tonight at @metmuseum in #nyc. Party on!
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UCBerkeley @UCB_Chemistry very well represented tonight in Stockholm #nobelweek @doudna_lab @CarolynBertozzi @christhechang
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Today I decided that #directedevolution is finally ready to be run entirely by #machinelearning. No more painful experiments to get your long-dreamed-for #enzymes! Grad students and postdocs can just push a button.
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In my #scientist era at #TaylorSwift premiere in LA. @GordonConf made this tshirt for all girl scientists!
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My grandson watching @NASAPersevere landing live!! All of us were on the edge of our seats. Congrats! #Mars2020
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TY for support (or not), and for joining this important conversation! Realize now that tongue-in-cheek 'bit busy' remark was unclear to many. With more than 1500 invitations since Prize in 2018, just responding takes more time than I have. Can't do it all. It's ok.
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April 4 will be my appearance on @bigbangtheory. But don't blink or you'll miss me!.
At last #bigbangtheory adds real-world #WomenInScience representation w/ guest Dr. Frances H. Arnold, 2018 Nobel Laureate, only 5th woman to be awarded the prize. 🧪.Hanging w/ real and fake scientists.- #billprady .Laureates: G.Smoot (physics 2006), K.Thorne (physics 2017)
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My motto, shared for 29 years with my three children: "I'm not perfect, but I'm good enough." Works for me. Seems to work for a lot of us.
TY for support (or not), and for joining this important conversation! Realize now that tongue-in-cheek 'bit busy' remark was unclear to many. With more than 1500 invitations since Prize in 2018, just responding takes more time than I have. Can't do it all. It's ok.
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Well, I never thought i would end up on the same list as Dolly Parton and Kris Jenner! Never too late. .
😍😍😍Wow, alumna and @NobelPrize laureate @francesarnold joins @DollyParton, #AngelaBassett, and lifestyle guru @KrisJenner on this year’s @Forbes '50 over 50' list. A rock star in every universe!
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We were not sure it was possible, but we found a little activity in an engineered #cytochromeP450 #enzyme. Once you have a starting point, you are golden. #directedevolution.
Enzymes have been evolved to tackle one of the most difficult reactions in chemical synthesis, the direct functionalisation of alkyl C-H bonds, according to a study published in Nature.
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Celebrating Rudy Marcus’ 100th birthday @Caltech @CaltechCCE @NobelPrize . Still loving #chemistry!!
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I was saddened to hear that my friend Dan Tawfik died doing what he loved--climbing. I learned so much from him about protein evolution, always looked forward to reading, and teaching from, his papers.
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Thank you, @SundarPichai! I could not be more excited about having more work to do. front row seat to the future @google and Alphabet.
I’m thrilled to welcome @francesarnold to the Alphabet Board of Directors. Frances brings incredible academic and industry expertise with a career spanning chemistry, engineering, renewable energy and more -- and a Nobel Prize in Chemistry. Looking forward to working with her!.
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Tonight the @smithsoniannpg honored some very special Americans. Thank you, Dr. Fauci, for everything you have done for us. I encourage all of you to see his very moving portrait in the #NationalPortraitGallery. #NPG
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Sitting on my son's yard art--I mean motorcycle--project.
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With #BobGrubbs and Rudy Marcus at the Athenaeum. Can't feel so special when ten percent of the @CaltechCCE senior faculty had a #NobelPrize (Ahmed Zewail, too). Bob, we will miss you.
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Hmm. First female scientist cameo on #BigBangTheory in 12 seasons. Not such a good record, but at least it was done!.
The Big Bang Theory Season 12, Episode 18 Recap: Sheldon and Amy's Uncertain Nobel Hopes Frances Arnold, the first female scientist to play herself on the series try to help Amy and Sheldon with their Nobel hopes on The Big Bang Theory.
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Age appropriate wheels! What are YOU doing this weekend?
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Correction: it includes "Hope over fear. Unity over division. Science over fiction. Truth over lies.".
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So excited for David Baker, Demis @demishassabis, and John Jumper! #Proteins rock!.
BREAKING NEWS.The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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I am going to embarrass my wonderful fitness trainer (and nephew) @SamShapeTrain in #Pittsburgh by putting the word out that he is a lovely person who would like to meet a really nice girl. Maybe one of you #chem grad students?.
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Just when we thought it could not possibly get worse. .
Justice Ruth Bader Ginsburg, Champion Of Gender Equality, Dies At 87
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I snagged two cookies with the Presidential Seal on exiting the Oval Office yesterday. like the chocolate @NobelPrize medals, seems a shame to eat them.
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This is about as cool as it gets #syntheticbiology #directedevolution: Conversion of Escherichia coli to Generate All Biomass Carbon from CO2
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Just a peaceful cabin in the woods. No electricity, no phone. Running water is the stream. Back to another way of life, 10 miles from @Caltech .
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Scientists of Twitter! The world needs more reminders that we're living, breathing human beings with lives outside a lab. Quote tweet this with a picture of you doing not-science!. No water, no electricity, all home sweet home. I miss 137.
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OK, so now the cat's outta the bag--my role on #bigbangtheory is throwing away perfectly good xxx cookies! BTW that office/desk is way more neat than my own. .
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Nobel laureates and science groups demand NIH review decision to kill coronavirus grant
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@CarolynBertozzi @Caltech @NobelPrize There are many great women in #Chemistry-in fact, I expect to see a long train of Nobel Prizes to women like @CarolynBertozzi, Jennifer Doudna, Emmanuelle Charpentier, Judith Klinman, @Sanford_Lab, @sarah_reisman and many more.
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Thanks @sundapichai! Excited to work with you and the teams at Alphabet and @google.
I’m thrilled to welcome @francesarnold to the Alphabet Board of Directors. Frances brings incredible academic and industry expertise with a career spanning chemistry, engineering, renewable energy and more -- and a Nobel Prize in Chemistry. Looking forward to working with her!.
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When we published the first #enzyme to MAKE carbon-silicon bonds back in 2016, some people asked us to BREAK them, so these man-made compounds would not persist in the environment. We finally made the first steps toward that:
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I crashed her Royal Society induction and invited myself to dinner with you @ProfG! So happy for @carolynbertozzi #ChemNobel. #NobelPrize2022.
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Mothers and sons everywhere, enjoy my son's response to my early-morning call: Caltech Mom Wins #NobelPrize, Son Is JPL Mars Flight Tech
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The rain stopped long enough for us all to celebrate Mrs and Mr Hosea Nelson! @caltechCCE @theNelsonLab. And, how nice of them to choose flowers to match my outfit!
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I apologize for all the #cactus photos, but this was too good to leave out. Cactus gone wild. Be well.
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Greetings from a #Sinaloa cornfield that is protected by @Provivitm #pheromones. This is a project ten years in the making, and now in the hands of farmers who want to reduce #insecticides and protect #biodiversity. @pedroslcoelho @ProviviMx
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Another huge win for #PackardFellows! Do you know that all three US women who won #NobelPrize in the last 3 years are also #PackardFellows? TY to the @PackardFoundation for critical early support of scientists and engineers.
Jennifer A. Doudna, Packard Fellow and longtime Advisory Panel member, and microbiologist @e__charpentier receive this year's #NobelPrize in Chemistry for the development of a method for genome editing. Congrats @doudna_lab! @NobelPrize #PackardFellows.
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Photo taken in front of Latimer Hall @UCB_Chemistry in the early 1980s. Good ol' days.
The star of enzyme engineering and fifth woman to receive the Chemistry Prize - @francesarnold. Arnold uses the process of evolution to make new and better enzymes. Their uses include more environmentally friendly manufacturing of chemical substances, such as pharmaceuticals.
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These are not secrets to success. More like 'how to do it the hard way'. I hope my sons don't read this.
How does a teenage runaway turn into a @NobelPrize Laureate? @francesarnold did it - and told @IBDinvestors how. You won't look at your life the same after reading this.
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Pretty impressive! Perhaps we can now move to the protein function problem?.
.@DeepMind's incredible AI-powered protein folding breakthrough will help us better understand one of life’s fundamental building blocks + enable researchers to tackle new and hard problems, from fighting diseases to environmental sustainability.
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Like my outfit? @UniPadova. Finally I have a degree in #chemistry!.
Honoris causa PhD in Chemical Sciences, just before the opening @francesarnold @UniPadova @ServizioRicerc @DiSC_UniPD
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This is so @caltech: #basketballs signed by #NobelLaureates. (There's so many here that there was almost no room left.)
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So sorry this could not take place in Stockholm. but just wait a year. I'll be there to celebrate Emmanuelle and Jennifer again.
Watch the very moment 2020 Chemistry Laureates Emmanuelle Charpentier and Jennifer Doudna receive their Nobel Prizes. They are awarded the 2020 #NobelPrize in Chemistry for their work on CRISPR/Cas9, a tool used to edit genomes.
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Happy #MothersDay to all you wonderful mothers. I miss mine today. My children and grandchildren make the many challenges of being a mother wholly worth it.
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Proud to announce that Nobel Laureate Frances Arnold @francesarnold from @Caltech is Closing #LatinXChem Webinar speaker on September 18, 2020, 16:00 h (UTC). August 25. Registration deadline.September 7. LatinXChem Twitter Conference. Poster registration.
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Just some #scientists in beautiful #Chile @congresofuturo. #DonnaStrickland first female #NobelPrize in physics in 55 years.
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Now THIS is an #enzyme cocktail! Thank you @FourSeasons Oahu, such a beautiful, peaceful place.
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My son is the one in the bunny suit. He has not seen his wife or unborn child since Feb. 10. Launch to Mars is July 30. Baby due September. Dedication!
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I think it is stunning.
This year's #NobelPrize diplomas have been handed out today to Chemistry laureates Frances Arnold (diploma below), George Smith and Sir Gregory Winter.
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You can see me in the trailer!!! The Big Bang Theory teases Nobel prize plot ahead of final season return via @MetroUK.
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OMG I got to go to @NASAJPL, don planetary protection gear, and see what my son James is working on!
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My brother Bill Arnold with #DonnaStrickland and me, on our way to the royal palace for intimate dinner for 150 with the royal family! #Cinderella #nobelprize
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