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Dr. Paul De Santis, PharmD Profile
Dr. Paul De Santis, PharmD

@DrPaulyDeSantis

Followers
6,609
Following
4,153
Media
2,098
Statuses
45,189

Opinions are my own: Former GLG Council Member (Oncology, IO, CAR T)

Joined August 2012
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@jimiuorio Best ROI in our history, we have destroyed 50% of the Russian army, our 75+ year enemy. Furthermore the “billions” given to Ukraine isn’t cash, its mostly BILLIONS in contracts to Lockheed Martin, Raytheon, and other major defense contractors who are hiring as many American’s as
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@jimiuorio Best ROI in our history, we have destroyed 50% of the Russian army, our 75+ year enemy. Furthermore the “billions” given to Ukraine isn’t cash, its mostly BILLIONS in contracts to Lockheed Martin, Raytheon, and other major defense contractors who are hiring as many American’s as
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@RALee85 That’s what I’ve been saying. Interesting to note Japan making territorial claims against Russia today on the far east:
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 months
@DavidSacks Absolutely the worst hot take I have ever read on this devolving platform
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
When you peddle Russian propaganda as a US congressman = Compromised by the Russian FSB… #CompromisedRepublican
@BasedMikeLee
Mike Lee
11 months
Putin is evil. And he has nukes. So let’s not go to war with him—either directly or through a proxy—if we can possibly avoid it. We can. #NotOurWar
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@Heritage This is deplorable and disinformation.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@SpencerGuard The longer this goes the better for Ukraine to achieve military stalemate, but painful/tragic for the populace. Hope we can establish a supply chain of food, water, meds, and other supplies to sustain all major population centers.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@lavern_spicer Try reading a history book on the period of 1930-1945 and will become ABUNDANTLY CLEAR why there is no greater strategic imperative for the United States than making sure Ukraine crushes genocidal Russian aggression. #StandWithUkraine 💯
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@ChuckPfarrer “Deep Fake” I believe this is called
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@BasedMikeLee 1000% YES 🙌
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@GermanAmbUSA @POTUS @Bundeskanzler This is what i was asking for the other day. Bravo, Germany's MORAL COMPASS is finally slowly turning back to true North.👏 🇩🇪🤝🇺🇸
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
13 days
@AndrewPerpetua I appreciate Ukraine finally reintroducing the element of surprise and being unpredictable. We’ve lost that since summer 2023
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@ZelenskyyUa @SpeakerPelosi Wow 👏🏻 🇺🇦🇺🇸
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@RALee85 Maybe, but time is not on Russia’s side, their replacement forces will only perform worse, morale can only go so low before widespread desertion.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@Eric_Schmitt BOOM 🇺🇦 🇺🇦🇺🇦 supporting Ukraine is the way forward.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@ashlee_leeee @JacquiHeinrich More interested in his connection to Russian FSB
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
20 days
@the_engi_nerd Now imagine being Putin, shaking right now thinking about 300 of these infiltrating Russian air space undetected…😆
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@MarkHertling @Acosta You nailed the assessment of Azovstal today 🙏🏻🇺🇦. It was a victory even though it doesn’t seem that way. The military objective was accomplished (delay flow of up to 12K russians elsewhere for 2 months).
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@SenRichardBlack What planet do you live on? It is certainly not earth sir. Prescription: stop drinking Vatnik tea (propaganda) and cease accepting all vatnik “donations” (bribes) ✅
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@mtracey CRIMEA IS UKRAINE...Only sanctuary Russia has moving forward is IN RUSSIA. They don't like the heat, then they can retreat and head back to RUSSIA.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@ForIn2020 @JoshuaDrakes2 @haynesdeborah Or like UK going to war with Ireland… oh wait… that happened
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@McFaul We need more than sanctions...Sanctions are weak. This is Poland 1939!!!!
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@jimiuorio Got your back @jimiuorio 👍 From now on when you hear the disinformation on “billions to Ukraine,” please think instead “long dollar” and “buy more Lockheed Martin” because American economy and our industries are the ones benefitting, while unfortunately Ukrainian’s are making
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
4 years
For the CAR-T folk out there. $FATE now is at $JUNO takeover valuation ~$10B and could reach $KITE soon at this rate. All on <5 patients worth of data and probability of success <30% at this point vs >50-100 pts worth of data with $JUNO and $KITE 💡 THINK about that🤔 #TcellRx
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 months
@afnanullahkh Hamas are Nazis see above ⬆️
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 months
@UNGeneva YOU HAVE STAYED SILENT DURING RUSSIAS WAR IN UKRAINE…. YOU HAVE LOST ALL CREDIBILITY
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
8 months
@mattgaetz Tell Putin to seek peace he is the one waging the war… leave Ukraine and there shall be instant peace call your people in Russia and demand full military withdrawal from Ukraine and stop blaming the victims and start blaming the aggressor.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@mattgaetz Support Ukraine and stop peddling Russian propaganda.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@jimiuorio Here is a chart of the funds from UKR Security Assitance flowing into US Industry showing ~$15B just for 4 major defense contractors...note this isn't comprehensive...and underrepresents the full amounts:
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@JoeyMannarinoUS You are deplorable and a shame to every Italian American, please go away 🤡
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@ClementLeeMD Agree, but what triggered this tweet today?
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@RepDonBacon Thank you sir 🇺🇸 🤝 🇺🇦.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 months
@MarkHertling Worth a thread 🧵
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@noclador @Volksbund Big opportunity for DNA analysis to ID MIA soldiers and recovery of there remains… likely German, Italian, and Soviet will be recovered
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
7 years
Most biotech's around 20-years + before being acquired, notable outlier $RCPT acquired by $CELG after 6 yrs, and $VRUS by $GILD after 13-yrs
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@Teoyaomiquu This is the most brilliant russian tweet in history. You CANNOT win!
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@RandPaul How much did the Russian FSB give you to sell your soul?
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 months
@KateGoesTech I don’t think such comparisons or criticisms are conducive to building strong support for Ukraine in the US. Which is critical right now.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@AndrewPerpetua Plenty more good times ahead “remember that time Ukraine retook Melitopol and Berdyansk” etc etc…
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@mattgaetz Yet you support Russia-->who supports Iran--> who supports HAMAS....You need to: Support Ukraine--> Defeat Russia --> weaken Iran --> weaken HAMAS....
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 months
Even with CAR T or ASCT, only ~25% of pts are “cured”…unmet need remains pretty high, despite meaningful improvement over past 7 years. #EHA24 #lymsm via: @AnnaSureda5
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@randymot4 It will probably just “additional types of munitions for HiMARS”
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@CasualArtyFan About 5,000 sq.kms the past 5-6 weeks 👏🏻
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@RandPaul Your comrade below has a message:
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@IAPonomarenko As am I, an American in awe of their bravery, courage, and undying patriotism. We are all supporting them and praying for them.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@AndrewPerpetua Yes you do need to
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@bizzlewizzle22t @SpencerGuard Everywhere… in WWII Stalin mobilized entire population of Moscow/Stalingrad (many more) and built defenses around entire cities.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@ACTBrigitte @Eric_Schmitt Move to Russia then, or get ready to send your kids to Europe in another world war… UKR must defeat Russia… if you don’t support defeating our #1 enemy since 1945 then you should be investigated by the FBI for potentially being compromised by the FSB in Russia.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@julianbarnes @John_A_Ridge @KofmanMichael another nail in the coffin of Russia. I’ve always pushed back against those who fell into the Russian propaganda that they’d never run out of munitions. Victory lap. @CraigM_Regan
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
Never forget Russian civilian culture praises Wagner war criminals as celebrities.
@Osinttechnical
OSINTtechnical
1 year
Definitely something indicative about the general Russian populace’s feelings for the Russian government and especially the MOD/Army as the people of Rostov cheer and celebrate Wagner as they leave.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@SecDef Agenda Item 1: ATACMS for 🇺🇦
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
8 months
@McFaul Legitimately, what is Biden administrations problems with being strong instead of weak cowards?
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
3 years
Pola-R-CHP BEATS R-CHOP on PFS in 1L DLBCL… no data provided, will be presented likely at #ASH21 @graham74GC called it 12+ months ago… hopefully its > 2-3% improvement #lymsm
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
7 years
Drug Spend (% of total healthcare spend) has remained between 9-12% since 2000 vs 55-60% for Professional Services & Hospital Care $IBB $SPY
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
8 years
All I-O Combination Trials as of YE16, via Chen et al @genentech thx for the most impressionable I-O review YET $AZN $MRK $BMY $ROG $INCY
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@rajan_menon_ Goodbye Kissinger
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@Teoyaomiquu @LibertyUkraineF This defines “force multiplier” effect… cc: @CasualArtyFan
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
3 years
@AriFleischer Genocide Olympics, refuse to watch a single event, or watch any news covering it.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
7 years
Surprising comments from $GILD on IO and CART space $JUNO $KITE
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 month
@EdwardTHardy @noclador Sorry, seeing someone get shot, and able to get themselves up after immediately does not support your claim.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@RepTroyNehls Your country is ashamed of you for supporting Putin. Sounds like the FSBs influence campaign (bribes etc) has worked on Republicans. #NAFO #Article5
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
7 years
#ESMO17 loving beautiful Madrid... what a great place.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
7 years
Summary Results: Top 3 Most Promising Agents $INCY $CRVS $ADRO $BMY $NVS $PBMD
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 months
@ShaykhSulaiman Flagging for others that this is propaganda and completely inaccurate
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@SpencerGuard I reject the claim “many Americans are growing weary of supporting Ukraine”
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
3 years
@DGlaucomflecken What about stem cell transplanters/ “CAR T Cell therapist” what would they make?
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@vonderleyen @calxandr For what it’s worth, I will be glad to pay $10/gallon to support EU independence from Russian energy. Very happy to see EU make the only moral choice 🇺🇸🇪🇺
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 months
@RepCori Pro-terrorism is a thing now apparently?
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
4 years
@Fxhedgers Cancel Culture is real...and its beyond absurd how the sheep (population) just accept this.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@J_GansMorse @nytopinion Jesus the @nytimes published this? Clearly infiltrated by Russian payoffs.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@RALee85 Curious how Russians are procuring Austrian weapons…
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@krshya @RepDonBacon @Ming_the_Husker Wrong Russian BOT… Ukraine has recaptured >50% of territory Russia captured since Feb’22
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@SecDef ATACMS
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
3 years
@RealJamesWoods Literally true, we could be sitting here 4-12 wks from now wondering how Taiwan fell in <24 hrs.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@SrihariNaiduMD @AjKavanaugh @hospital_adm @SCAI @ACCinTouch @djc795 @CMichaelGibson @DrJMarine @JCigarroaMD @heartdoc45 @AnkurKalraMD Its the 300 administrators (bureaucracy) salaries that are the enemy… thanks for taking those late night calls 🙏🏻
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@oleksiireznikov @POTUS @SecDef God bless Ukraine 🇺🇦
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
9 months
@Spartan_News1 @StarskyUA @RealJakeBroe @ArturRehi More importantly, the black sea fleet has lost its ability to operate freely in the black sea… and that is the strategic victory accomplished this summer.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@vcdgf555 No, I disagree, time to put an end to this.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 days
@PhilGordon46 @VP Can you explain your close ties to Iran? Hard to take anything you say seriously until that is clarified. How much money have you received from the IRGC? Serious question and open to discussion.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 months
Glofit+GemOx had an incredible topline mOS of 25 months vs. 12 months with RGemOx...however, subgroup analysis shows patients from Europe (21 mo) and North America (13.3 mo) had significantlly less OS benefit vs. RGemOx...this is likely due to CAR T and CD20 BsAb available to
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
1 year
@AndrewPerpetua Sounds like a snitch revealed the troop rotation
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
3 years
$CRSP: 1/n: Sell-Side Analysts completely miss the point. 1) The crux of the debate is that the efficacy of allo-CAR T is inferior relative to both CD20 bispecifics and auto-CAR T, not to mention weaker than Polivy and Monjuvi, but barely better than Xpovio.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
7 years
UPENN discontinued anti-CD22 CAR-T trial citing “lack of efficacy” $JUNO $NVS $GILD
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@AndrewPerpetua Test complete ✅💥
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
10 months
@UAWeapons This is very disappointing and a huge loss
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@ChuckPfarrer Heard there have been a lot of Wagner surrendering past 2 weeks.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
3 years
"I can imagine more patients will get bispecifics than CAR T" once said by @JohnPLeonardMD around #ASH20 . Updated glofitamab data (n=175) #ASH21 by @mike_dickinson1 54% ORR / 39% CR (13.4 mo f/u), mDOR 29.4 months! 😍with "fixed tx duration & ‘off-the-shelf’ accessibility" 1/2
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
4 years
As if 2020 couldnt get any more weird...Pic taken over middle pacific at ~45-49,000’ by family member (pilot)
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@RealCynicalFox @CSIS Your friendly Reminder @CSIS DOESNT KNOW what they’re talking about or do any serious deep dive work into this as evidenced by their factually incorrect “analysis” on this topic last time you propagated their name.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
8 years
Biotech just exited the longest bear market on record according to Bespoke $IBB $GILD $CELG $AMGN $JUNO $KITE $BIIB
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
@McFaul Don’t worry sir, I think you also do not realize how many millions of us suffer in silence and choose not to engage with these genocidal sympathizers. You are not alone.
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
2 years
@SpencerGuard @ZelenskyyUa Beyond tragic, but with very heroic actions like this, they will live-on for generations to come #SlavaUkraini 🇺🇦
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
11 months
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@DrPaulyDeSantis
Dr. Paul De Santis, PharmD
19 days
@Teoyaomiquu @Atlas_Hellfire Sweden gave UKR a similar type of ISR plane
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