PLEASE RETWEET: We have two available post-doc positions to work on an
@ERC_Research
funded project to study transcription inhibition during mitosis.
@IGCiencia
More info:
I am thrilled that our
@ciencia_pt
FCT project TopoChromo was granted to study regulation of DNA topology in mitosis!!! This is my *very first* FCT project after 10 years in PT and from my experience, much harder to get than an ERC grant!!
BIG NEWS: As of today, I am an Associate Professor at the Católica Medical School (UCP) and will serve as vice-director of the new Católica Biomedical Research Centre. Excited to share this adventure with
@mjamorim1
@lmvteixeira
and
@ClaudioAFranco1
1/n
PLEASE RT *Job Alert* We have an open post-doc position to work on an exciting
@ERC_Research
project on
#transcription
inactivation during
#mitosis
. More info about the job ad/lab: PM for informal enquiries
Proud to announce the
#ERCCoG
to our lab, with the project ChromoSilence, and to contribute to "women gaining ground" in these prestigious awards!!!
@IGCiencia
@ERC_Research
PLEASE RT *deadline extended* We have an open post-doc position to work on an exciting
@ERC_Research
project on
#transcription
inactivation during
#mitosis
. More info about the job ad/lab: PM for informal enquiries
We are proud to see our work on mitotic transcription termination and sister chromatid resolution highlighted in the
@emboreports
cover. Isn't this the prettiest cover ever 😀 ?? Link to paper:
Have a look at our September issue.
The cover features work by Raquel Oliveira
@CHR_lab
@IGCiencia
and co-workers showing that a dual-function SNF2 protein drives
#chromatid
resolution and nascent
#transcript
removal in
#mitosis
.
A much-improved version (kudos to peer-review) of our exciting story on the link between sister chromatid resolution and removal of nascent transcripts in
#mitosis
is *now out*
@emboreports
**NEW PREPRINT** 👇Amazing work by
@MargaridaMArauj
, in a fruitful collaboration with
@IATelleyLab
, showing how ER membranes impact on mitotic spindle
On my way back from 4 days of GREAT science at
#EMBOcellCycle2022
!! It was a privilege to present our work and even more to hear so many nice stories about this amazing engine!
Final moments of the
#10yearsCHRlab
day!!! Seeing Lisbon by the river and a river-side dinner were just PERFECT!! Many thanks Alexandra Tavares and
@i_milagre
for the organization!!
Check this - 170 happy scientists at
#ChromoPloidy2022
;
@IMBA
Vienna. We had today again a great line up of speakers, with a main focus on the role of aneuploidy and chromosomal instability in cancer.
PLEASE RT *JOB ALLERT*: We have one available post-doc position to work on an
@ERC_Research
funded project to study transcription inhibition during mitosis.
@IGCiencia
More info:
Carvalhal et al
@IGCiencia
show that sister chromatid cohesion is highly resistant to cohesin loss. Nevertheless, partial cohesin decay compromises mitotic fidelity by impairing chromosome attachments
Proud to see the result of exciting office discussions and brainstorming sessions with my former office mate Diogo Castro (now
@i3S_UPorto
). And congratulations to Mario Soares (and all the others) for the excellent work!
@GenesDev
@IGCiencia
Here, Soares et al show an important role for differential binding of TFs to mitotic chromosomes, governed by their electrostatic properties, in defining the temporal order of transcriptional reactivation during mitosis-to-G1 transition.
@i3S_UPorto
*NEW PREPRINT* Excited to share our latest work on an unexpected link between sister chromatid resolution and mitotic transcription termination! Fruitful collaboration with
@martinho_lab
! Great teamwork by
@CatarinaCarmo19
,
@JoaoNSCoelho
et al
BIG CONGRATULATIONS to “our”
@SCarvalhalB
for winning one of the
@MaratonaSaude
awards. This is certainly well deserved and will be a major help to start her own lab on mitotic fidelity in rare diseases. You rock!!! Fly high!!!
Our manuscript on how SAC inhibition can restore mitotic fidelity in cells with sister chromatid cohesion defects. Great collaboration with
@martinho_lab
!!!
Pls RT: We have an open PhD position in our lab within the MSCA European Doctoral Network COHESINET to uncover novel regulators of sister chromatid cohesion. More info here:
What happens if someone suddenly messes with your
#chromosomes
? Novel tool for inducing chromosomal imbalance in
#FruitFlies
(cohesin depletion) in an acute & controlled manner reveals that the brain is most sensitive to abnormal karyotypes
#PLOSBiology
It was an honour to present at such a special meeting and get to know other recently nominated
@EMBO
members (and “older” too). Many thanks to
@mitosisrocks
for the nomination and to all members and staff for the warm welcome.
*please retweet* CHR lab is hiring! We are looking for research technicians to join our lab under the scope of an
@ERC_Research
-funded project to study transcriptional inactivation in mitosis. More info in the link or via PM
Today our PhD Students
@MargaridaMArauj
and
@AT_Eugenio
presented their PhD thesis work at the
@IGCiencia
seminars! Congrats to both for the hard work and amazing presentations! 🧬
Great gallery and happy moments shared!!! And so happy to see amazing messages from alumni and colleagues that could not be here!! No words to describe how emotional this was!!
#10yearsCHRlab
Check our latest work on acute and reversible
#cohesin
depletion and the fate of
#aneuploid
cells. Just ported on bioRxiv. Comments are most welcomed :)
"Delayed aneuploidy stress response of neural stem cells impairs adult lifespan in flies"
I never imagined I would once co-author a paper about gorillas and their (lack of) spermatogenesis efficiency but here it is!!! My contribution was really minor, all mastered by
@germcells
,
@DevoEvoMed
and others that really know about this stuff! And it’s a really cool story!!
Today, we will be tackling one of the great mysteries of biology: why are gorillas so bad at producing sperm? This was the challenge that mastermind
@DevoEvoMed
issued to a panel of experts (and to yr beloved
@germcells
as well 🤪). Want to know more? Let’s get this 🧵 rolling…
Partial
#cohesin
loss has little effect on sister chromatid cohesion but leads to increased duration of
#mitosis
and susceptibility to errors in chromosome segregation, say Carvalhal et al
@IGCiencia
🚨Newly-minted
#PhD
alert!🚨 Cíntia Ramos (and her Mini-me) fresh out of defending the great work she did
@CHR_lab
. Cíntia was part of the
@PGCD_IGC
program and she studied if there’s more to
#condensin
than just packing
#chromosomes
. Wishing her all the best for her career 💪
Check our review on
#transcription
factors binding to mitotic
#chromosomes
and gene expression re-activation after
#mitosis
🧬From a fruitful collaboration with my former office mate Diogo Castro, and our talented jointly student Mario Soares!
2022 has been a year full of new challenges. Working as career advisor at
@ChaperoneOnline
has been a truly rewarding one. I am very proud of this recognition and even more of all the young scientists that I interacted with in individual or group sessions!
Super happy to see this paper out! Great collaboration with
@larsjansenlab
on the centromeres of human pluripotent stem cells. Congratulations Milagre et al for such an amazing work!!!
In a great collaboration with
@CHR_lab
at
@IGCiencia
, Inês Milagre and Carolina Pereira characterize, for the first time the basic organization of human pluripotent stem cell centromeres in
#OpenBiology
@RSocPublishing
Great piece from IGC communication team (by Ivana Martins) describing our work, and how
@IGCiencia
environment was critical to foster and test new ideas!
#chromosomes
#mitosis
Congratulations to our former PhD student Mihailo Mirkovic for being awarded both an
#ETH
postdoctoral fellowship and an
#EMBOfellowship
to continue his great work at Yves Barral lab.
Congratulations to our DOCTOR MIRKOVIC for such great work and outstanding defense! And special thanks to the jury members for the stimulating discussion!!!! (Zuzana Storchova, Geert Kops, Elio Sucena, Catarina Homem and Miguel Teixeira).
Our latest review, spearheaded by
@i_milagre
on the suboptimal mitotic fidelity of human pluripotent stem cells. Many intriguing questions are still open!
I am an outsider to the field and I am not in a position to have say on this, but I have always admired
@AndreaMusacchi1
reasoning on others issues I could follow in more detail. So I would say this is at least some food for thought..
(1/) I hope you will appreciate that once you stop ignoring site-specific interactions, the entire PS idea applied to our cells reveals itself for what it is: a skyscraper of cards. There are no good reason to assume, and it is highly implausible, that physiological interactions
Another great celebration of “beginnings” by
@marianabs2
, former
@CHR_lab
master student, showing us her super interesting and thought provoking PhD work at
@Neuro_CF
at Rhiner Lab.
Call for Group Leader with tenure track, at the new Católica Biomedical Research Centre, is still open until 31 October. We are seeking researchers from basic biology to medical research, with a particular interest in Data Science. More details at:
CBR will be hosted within the
@IGCiencia
campus (so the move won’t be that big) and I will retain a double-affiliation for the next two years. I am deeply thankful to
@IGCiencia
for the excellent support over the past ten years that made this next step possible. 3/n
PLEASE RT *Job Alert* We have an open post-doc position to work on an exciting
@ERC_Research
project on
#transcription
inactivation during
#mitosis
. More info about the job ad/lab: PM for informal enquiries
Proud to be one of the 240 women scientists and staff that make
@IGCiencia
a special place to be!Diversity at all levels- from mathematics, physics, engineering, biology and biochemistry; from different continents.
#IDWGS2018
#Diversity
#WomenInScienceDay
I’ll be also presenting a poster on the Gene Structure and Transcription section on Wednesday 11am EST - P1036z come check it out :) I’ll be showing cool stuff on inactivation of
#transcription
during
#mitosis
!
It was particularly emotional to have such nice and touching words from my mentors, Claudio Sunkel and Kim Nasmyth
@Cohesin_Lab
!! No words to describe how much they influenced my passion for science and the way of doing science!! Thank you!!
Foi um prazer fazer esta viagem ao início da
@PARSUK_
:) mas um prazer ainda maior ver o “adolescente” maduro e sólido que esta associação é hoje!
#luso2023
#proudlab
Neide Silva completed her Masters with great success 🎊🎉🥳! Fruitful collaboration with
@germcells
!! Engaging discussion led by
@AnaRPFMarques
! Many thanks to all involved and huge congratulations to Neide!!
1/n - Twitterverse, let me introduce you to Neide Silva, as she fearlessly defended, earlier today, her Master's thesis on a new role for Condensin II during spermatogenesis (stay tuned for that one).
After a month working with us at
@CHR_lab
, Milica yesterday kick started the final day of the Summer school at
@IGCiencia
, a wonderful hands-on experience for students interested in science career. Well done!!👏👏👏
#proud
#grateful
Do not miss
@MargaridaAraj13
poster
#ASCBEMBO2019
!!! She will be presenting our work in collaboration with
@IATelleyLab
on how ER influences chromosome segregation!!! Looking forward to the always great feedback of this amazing community!
Really happy to represent
@IATelleyLab
and
@CHR_lab
as a first timer at the
#ASCBEMBO2019
!
Check out my poster (B226) on Tuesday from 1:30 to 3:00 pm at the Spindle Assembly 2 session! I promise a lot of cool images of the ER and mitotic spindle!
#mitosis
So nice to see the very first member of the
@CHR_lab
to present how 10 years later he keeps thinking about mitosis and chromosome segregation, now with some exiting new findings and ideas! By Mihailo Mirkovic from Yves Barral lab.
#10yearsCHRlab
@ChriZieri
Week 1 - Tuesday, May 19th at 11 am EDT
Keynotes: Beth Sullivan
@dicentric
(Duke University) and Aaron Straight
@astraight
(Stanford University)
Simon Giunta, Hiro Funabiki lab
Leonardo Gomes de Lima, Jen Gerton lab
PLEASE RT *JOB ALLERT*: We have one available post-doc position to work on an
@ERC_Research
funded project to study transcription inhibition during mitosis.
@IGCiencia
More info:
It is ON!!!! Call for Group Leaders at IGC! Experimental and Theoretical Science across scales! Looking for the best talent and fit for institute. Closes March 1st. Apply, apply, apply!!!! Great place, wonderful colleagues! Weather and food also ok :-).
CBR aims to strengthen the link between research, teaching, and the practice of medicine, promoting the discovery of solutions to improve the prevention, diagnosis and treatment of human diseases. 2/n
@IGCcentrioles
@IGCiencia
Many thanks! Quite excited to see where this goes and counting with IGC for its success :) I am also thrilled to continue to be part of IGC for the next 2 years, so we don’t need to say goodbye yet!
And now the institute's press release on our recent work on centromeres in stem cells (with
@larsjansenlab
). Congratulations
@i_milagre
et al for the excellent work!!
It's never too much to stress how much being part of the
@EMBO_YIP
community was important for my career so far, which certainly contributed to this
#ERCCoG
. Many thanks!!!
Final scientific talk of the day with great and inspiring work on neurodegenerative diseases by Ines Bras, former
@CHR_lab
intern. So nice to see how her career moved into great adventures :)
#10yearsCHRlab
@RibeiroCarlitos
I suspect no one is actually submitting it at the moment... that site is just impossible 😡
@ciencia_pt
will likely postpone the deadline given the technical impediments...