Patrik Brundin MD PhD
@BrundinPatrik
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MD PhD, Therapeutic Area Leader for Movement disorders at @Roche Expert on #Parkinson and #Huntington disease. Views expressed here are my own.
Grand Rapids, MI, USA
Joined October 2018
#MJFox will receive Presidential Medal of Freedom! Among many things, Michael J Fox is recognized for his advocacy and research support regarding #Parkinson disease. Incredibly well deserved! #synuclein #biomarker #Lewybody #therapeutics
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Seismic shift in the US model for research funding. Look to Europe for inspiration!?
Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead, what is known as “indirect costs.” Today, NIH lowered the maximum indirect cost rate research institutions can charge the government to 15%, above what many major foundations allow and much lower than the 60%+ that some institutions charge the government today. This change will save more than $4B a year effective immediately.
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RT @NIH: Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead,…
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Svenskar tvättade och gnuggade. Munskydd förlöjligades. Och först nu börjar man gradvis erkänna att man gjorde så många fel…
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RT @JohnTadross: 🚨 New paper in @Nature! 🚨 We’ve mapped the human hypothalamus in unprecedented detail, revealing key differences from mice…
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@ScienceofPD It is odd that the Discussion mentions a clinical trial with GLP-1 agonist in PD that has not recruited in 7 years (NCT03659682), but in the same paragraph does not mention the Karolinska trial with exenatide in PD, that should already be finished (NCT04305002). Any insights?
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RT @MichaelOkun: The randomized trial results are in for the GLP-1 drug Exenatide for Parkinson's disease. Spoiler: NO symptomatic or disea…
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RT @darbysaxbe: I need people to understand how difficult it is to get an NIH grant. You spend months writing a proposal, following strict…
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No kiddin’, might it sometimes all start in the kidney? Propagation of pathologic α-synuclein from kidney to brain may contribute to #Parkinson’s disease | Nature Neuroscience. @ScienceofPD @peelaerts_w
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RT @AbhiLenka11: Neuro-PASC (post-COVID) patients exhibit similarly increased intraneuronal α-syn deposition, suggesting that α-syn accumul…
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@NiallHarbison Hoping there is not an underlying disease causing mechanical obstruction of her intestines. ❤️
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RT @uk_biobank: Today we’re launching the world’s most comprehensive study of proteins circulating in our bodies, which will transform rese…
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If you are feeling old, stay cool! You still have some time to go before you are 46,000 years old!
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Great review on #stemcell therapies from @Kirkeby_Lab who is affiliated with @Lund_Stem and @MultiparkL at @medfak_LU @lunduniversity
Since the derivation of hPSCs, technologies to control their differentiation and manufacturing have advanced immensely, enabling increasing numbers of clinical trials with #hPSC-derived products. 🔎 Learn more in this @CellStemCell review.
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RT @ESC_iPSC_News: Since the derivation of hPSCs, technologies to control their differentiation and manufacturing have advanced immensely,…
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RT @NEJM: Transthyretin amyloidosis is a progressive, fatal disease that often leads to cardiomyopathy. Research findings on vutrisiran for…
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@ScienceofPD @MichaelJFoxOrg Might be worth highlighting that this was in “early-stage Parkinson’s disease” with participants 2 years or less after diagnosis.
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