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Bo Wang Profile
Bo Wang

@BoWang87

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10K
Following
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Assistant Prof @UofT; CIFAR AI Chair @VectorInst; Chief AI Officer @UHN; former PHD, CS @Stanford; opinions my own. #AI #healthcare #biology #LLM

Toronto, Ontario
Joined September 2016
Don't wanna be here? Send us removal request.
@BoWang87
Bo Wang
5 days
DeepSeek-R1 is great, but it still does not handle genomics yet :) . ๐Ÿš€ Weโ€™re thrilled to announce that IntegrAO (pronounced "integral") ๐Ÿงฌ๐Ÿ”ฌโ€”our new multi-omics integration frameworkโ€”has been published in Nature Machine Intelligence!. ๐Ÿ“‘ Paper: ๐Ÿ’ป Code:
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@BoWang87
Bo Wang
2 years
๐ŸŽ‰Exciting Update of scGPT ๐ŸŽ‰: After receiving significant attention from the community since our April release, we're thrilled to announce the first major update for scGPT - a foundation model for single-cell multi-omic data. This update integrates community feedback and
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@BoWang87
Bo Wang
1 year
Interested in LLMs for genomic research but don't know where to start? looking for a review/survey to get started in this field? ๐Ÿ‘‡๐Ÿ‘‡๐Ÿ˜€. I am very excited to share that our review paper titled "To Transformers and Beyond: Large Language Models for the Genome" is now available as
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@BoWang87
Bo Wang
10 months
(1/5) Attention, Cellular Imaging Enthusiasts! . Thrilled to share that our Analysis "The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions" has been published in Nature Methods (@NatureMethods) ๐ŸŽ‰๐ŸŽ‰๐ŸŽ‰ . Cell segmentation is a critical component of
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@BoWang87
Bo Wang
2 months
Most MIT profs who I know are extremely honest and morally upright. I hope this is an exception.
@sunjiao123sun_
Jiao Sun
2 months
Mitigating racial bias from LLMs is a lot easier than removing it from humans! . Canโ€™t believe this happened at the best AI conference @NeurIPSConf . We have ethical reviews for authors, but missed it for invited speakers? ๐Ÿ˜ก
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@BoWang87
Bo Wang
11 months
๐Ÿ”ฌ Exciting News! Our manuscript, "scGPT: toward building a foundation model for single-cell multi-omics using generative AI" is now finally published in Nature Methods (@NatureMethods) ๐ŸŽ‰ !!! . (Re-)Introducing scGPT: A transformative foundation model engineered for single-cell
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@BoWang87
Bo Wang
1 year
๐ŸŽ‰ The best way to start the week is to find out that our MedSAM is finally published today in Nature Communications!. **Segment anything in medical images** .Paper: arXiv: Data & Code: MedSAM is the first
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@BoWang87
Bo Wang
6 months
๐Ÿš€ The Segment Anything Model (SAM) has been upgraded to SAM2, featuring an efficient image encoder for segmenting images and videos. But does SAM2 outperform SAM1 in medical image and video segmentation?. We're thrilled to present our paper "Segment Anything in Medical Images
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@BoWang87
Bo Wang
1 year
๐ŸŽ‰ Thrilled to announce the very first 2024 preprint from our lab: U-Mamba ๐Ÿ, a novel backbone for universal bio-medical image segmentation!. Background: Transformers have not transformed bio-medical images. While Transformers excel in general vision and language tasks, they
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@BoWang87
Bo Wang
1 year
Truly humbled to be promoted as the Chief AI Scientist at University Health Network, Canada's largest research hospital. My deepest gratitude to everyone who has supported and believed in me, especially the dedicated trainees and students in the lab. As we look to the future, I'm.
@UHN
University Health Network
1 year
Congratulations to Dr. @bowang87 UHN's Chief Artificial Intelligence (AI) Scientist. @camillebains1 of Canadian Press outlines how the pioneering role builds on the @UHNAIHUB and its potential to use machine learning to improve health care. Read more โ†’
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@BoWang87
Bo Wang
5 months
โ€œOur foundation model achieved state-of-art results on the benchmark!โ€
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@BoWang87
Bo Wang
11 months
couldnโ€™t agree more about the need for more computational biologists. More importantly, we must ensure they receive the recognition and support they deserve. Their work should never be dismissed as merely โ€œjust serviceโ€. Additionally, Iโ€™d like to remind everyone of the excellent
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@prmshra
parm
11 months
WE NEED COMPUTATIONAL PEOPLE IN BIOLOGY. WE NEED THEM IN DRUG DISCOVERY AND MULTI OMICS. WE NEED HARDWARE PEOPLE TO BUILD SPECIFIC AND PORTABLE DEVICES. BUT MOST IMPORTANTLY WE NEED DEVS. WE NEED TO MAKE OPEN ACCESS DATA AS ACCESSIBLE AS POSSIBLE. WE NEED COMPUTE GRANTS. GIVE.
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@BoWang87
Bo Wang
3 months
Excited to share CpGPT, a new foundation model for DNA methylation, crafted to understand the 'language' of epigenetics! ๐Ÿงฌ๐Ÿค–. Whatโ€™s CpGPT? .CpGPT is a transformer model pre-trained on CpGCorpus, a huge dataset of public DNA methylation info. By integrating sequence, positional,
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@BoWang87
Bo Wang
4 months
๐Ÿš€ We're thrilled to introduce Orthrus ๐Ÿงฌ๐Ÿ•โ€”a groundbreaking mature RNA foundation model designed to push the boundaries of RNA property prediction!. ๐Ÿ”ฌ What is Orthrus? .Orthrus is a Mamba-based RNA foundation model, pre-trained using a novel self-supervised contrastive learning
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@BoWang87
Bo Wang
11 months
**Is single-cell data integration a solved problem? **. Lots of great methods, but still not quite yet! Specifically, Check Dataset Imbalance! . ๐ŸŽ‰ Excited to announce that our study on dataset imbalances in single-cell analysis just hit Nature Biotechnology (@NatureBiotech)! ๐ŸŽ‰
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@BoWang87
Bo Wang
2 years
I usually don't talk about preprints, but I will make an exception here: .Introducing #MedSAM (Segment Anything in Medical Images for universal medical image segmentation! .๐Ÿ“ท 1st attempt adapting SAM to medical domains.๐Ÿ“ท Large-scale supervised training.
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@BoWang87
Bo Wang
1 year
State Spaces models (SSM) such as mamba have started to revolutionize languages, vision, and genomics, as a promising alternative to transformer architecture. How about graph data? . โค๏ธโ€๐Ÿ”ฅ Introducing Graph-Mamba, our latest innovation in Graph Learning for enhanced long-range graph
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@BoWang87
Bo Wang
1 year
Our recent preprint U-Mamba ( has sparked lots of interest in State Space Models (SSMs) or the Mamba model, particularly its adoptions in vision. Many people have reached out to request more educational materials for this new alternative to Transformers.
@BoWang87
Bo Wang
1 year
๐ŸŽ‰ Thrilled to announce the very first 2024 preprint from our lab: U-Mamba ๐Ÿ, a novel backbone for universal bio-medical image segmentation!. Background: Transformers have not transformed bio-medical images. While Transformers excel in general vision and language tasks, they
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@BoWang87
Bo Wang
2 years
(Re-)Introducing #ClinicalCamel ๐Ÿช: an innovative open-source conversational #LLM engineered specifically for healthcare: . Paper: Model weights in HF: Eval Scripts at Github: Live Demo:
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@BoWang87
Bo Wang
2 months
Biology is probably the only place with unlimited fossil fuel for AI ๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ”ฅ.
@_jasonwei
Jason Wei
2 months
Yall heard it from the man himself
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@BoWang87
Bo Wang
9 months
(1/3) ๐ŸŽ‰ Exciting News: Our WangLab team has won first place in the 2024 MEDIQA Clinical NLP competitions for the second consecutive year! ๐Ÿฅ‡๐Ÿฅ‡ . This year, MEDIQA 2024 has two tracks: 1) Medical Error Detection & Correction; 2) Multilingual & Multimodal Medical Answer
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@BoWang87
Bo Wang
1 year
One of the biggest challenges in #AI and #healthcare is how to collaboratively train large AI models from multiple hospitals without compromising patient privacy? . Thrilled to introduce our new paper, DeCaPH, which is now officially published in @TheLancet @eBioMedicine!
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@BoWang87
Bo Wang
1 year
**Updating the best open-source medical LLM**. ๐Ÿš€ Introducing Clinical Camel-70B, one of the best open-source medical Large Language Models for clinical research! Based on the new #Llama2-70B model from @MetaAI, our Clinical Camel-70B can surpass proprietary models like
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@BoWang87
Bo Wang
2 years
Thrilled to present our latest commentary in #NatureMethods on foundation models for biological image segmentation! A central task of leveraging biological images is the extraction of quantitative features that can be used to characterize and compare.
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@BoWang87
Bo Wang
2 years
@drkeithsiau Our medical chatbot (named Clinical camel, ) says it is Peutz-Jeghers Syndrome (PJS).
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@BoWang87
Bo Wang
6 months
After labor-intensive debugging, we finally deployed our MedSAM2 models available on Hugginface for medical and biological video segmentation. Welcome to try it. There are three advantages of this API: and upload videos of any length, no limitation on
@BoWang87
Bo Wang
6 months
๐Ÿš€ The Segment Anything Model (SAM) has been upgraded to SAM2, featuring an efficient image encoder for segmenting images and videos. But does SAM2 outperform SAM1 in medical image and video segmentation?. We're thrilled to present our paper "Segment Anything in Medical Images
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@BoWang87
Bo Wang
3 months
๐Ÿš€๐ŸŒฑ Large language of life models: foundation models for longevity and aging! . Our lab has recently been involved in two groundbreaking DNA methylation foundation models: CpGPT and MethylGPT! These โ€œLarge Language of Lifeโ€ models (@EricTopol) mark a new era in aging.
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@BoWang87
Bo Wang
10 months
(1/5) Very excited to announce that our paper titled "Tandem mass spectrum prediction for small molecules using graph transformers" has been published in Nature Machine Intelligence! . Paper: Code: This method, MassFormer, was
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@BoWang87
Bo Wang
4 months
I had the privilege of meeting Demis Hassabis and John Jumper at the Gairdner dinner in Toronto last year, where we discussed what the โ€œnext AlphaFold momentโ€ might look like. During our conversation, Demis shared his long-standing dream of creating virtual cellsโ€”an incredibly.
@demishassabis
Demis Hassabis
4 months
Winning the @NobelPrize is the honour of a lifetime and the realisation of a lifelong dream - it still hasnโ€™t really sunk in yet. With AlphaFold2 we cracked the 50-year grand challenge of protein structure prediction: predicting the 3D structure of a protein purely from its.
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@BoWang87
Bo Wang
2 years
๐Ÿ”ฌCan whole-slide Hematoxylin and eosin (H&E) stained histology images predict gene expression profiles in single-cell spatial omics? #spatial #SingleCell. Introduce our latest paper, BLEEP (Bi-modaL Embedding for Expression Prediction): a state-of-the-art tool predicting spatial
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@BoWang87
Bo Wang
1 year
Our #nature comment titled "To safely deploy generative AI in health care, models must be open source" is out today! ๐Ÿ™๐Ÿ™๐Ÿ˜€๐Ÿ˜€. In our Nature commentary (, we advocate for the essential role of open-source development in generative AI for healthcare. This.
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@BoWang87
Bo Wang
2 years
mRNA medicine has changed the world. Wonder how #AI can help with mRNA therapy development? Thrilled to share our latest collaboration with @BowenLi_lab! Our paper, "AGILE Platform: A Deep Learning-Powered Approach to Accelerate LNP Development for mRNA Delivery," showcases how
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@BoWang87
Bo Wang
1 year
Another amazing breakthrough of Mamba in Vision is just out: Vision Mamba (Vim) (paper: , a great work from @XinggangWang's group! . What is Vision Mamba?. Vision Mamba (Vim) is not just another model; Departing from conventional attention mechanisms, Vim
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@BoWang87
Bo Wang
2 months
๐Ÿš€ The era of foundation models for biology and medicine is hereโ€”and itโ€™s on fire! ๐Ÿ”ฅ. Our lab is at the forefront of this revolution, building cutting-edge models to transform biomedical research and healthcare:. ๐Ÿ”ฌ scGPT: Redefining single-cell omics with advanced foundation.
@gdb
Greg Brockman
2 months
During my sabbatical, one project I really enjoyed was training DNA foundation models with the team at @arcinstitute. I've long believed that deep learning should unlock unprecedented improvements in medicine and healthcare โ€” not just for humans but for animals too. I think this
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@BoWang87
Bo Wang
6 months
๐ŸŽ‰ Exciting News in Genomic Foundation Models! ๐ŸŽ‰. Genetic variants (GVs) are key in diagnosing and treating genetic diseases. With the plummeting costs of next-generation sequencing, we now have a treasure trove of GV data. But this surge presents a challenge for clinicians: how
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@BoWang87
Bo Wang
1 year
โœจ Excited to announce the first Workshop on Foundation Models for Medical Vision in #CVPR2024! . ๐Ÿ’กExplore the potential of foundation models in medical imaging to augment human intelligence and revolutionize patient care. โค๏ธโ€๐Ÿ”ฅWe are proud to host an esteemed lineup of speakers:
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@BoWang87
Bo Wang
6 months
๐ŸŽ‰ Excited to share our preprint: "ECG-FM: An Open Electrocardiogram Foundation Model"! ECG-FM is a transformer-based model, one of the pioneering open foundation models for ECG analysis. The electrocardiogram (ECG) is a widely used, cost-effective diagnostic test with great
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@BoWang87
Bo Wang
2 years
Every scientist has a lab website, but these websites are static, and often hard to navigate. The idea we had is, can we build a personalized chatbot for users to interact with the lab websites?. Say hello to Lab Walrus (, our #ChatBot designed to bring
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@BoWang87
Bo Wang
6 months
Thrilled to announce that our AGILE framework, an AI-guided LNP development for mRNA delivery, is now published in @NatureComms! ๐ŸŽ‰ This is a collaborative work with @BowenLi_lab. (Re-)Introducing the AGILE Platform: A Deep Learning-Powered Approach to Accelerate LNP Development
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@BoWang87
Bo Wang
2 years
mRNA medicine has changed the world. Wonder how #AI can help with mRNA therapy development? Thrilled to share our latest collaboration with @BowenLi_lab! Our paper, "AGILE Platform: A Deep Learning-Powered Approach to Accelerate LNP Development for mRNA Delivery," showcases how
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@BoWang87
Bo Wang
1 year
Great News: DeepVelo finally published in Genome Biology (@GenomeBiology)! ๐ŸŽ‰ ๐Ÿ™โค๏ธโ€๐Ÿ”ฅ. DeepVelo: Deep learning extends RNA velocity to multi-lineage systems with cell-specific kinetics. In-press: . #bioRxiv preprint (April 2022) :
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@BoWang87
Bo Wang
10 months
This is incredible! This trend, once unique to computer science, is now emerging in life sciences too. As AI continues to evolve, it prompts a big question: What does the future hold for academia? Could we see a shift, or even a disappearance, of traditional academic roles?.
@AlexJColville
Alex Colville
10 months
One of the biggest cultural shifts in life science PhD programs over the past decade - industry directly replacing academic jobs for graduates. Source: @NSF @DrChrisTSmith
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@BoWang87
Bo Wang
1 year
What is cooler than being featured by #nature once?.The answer is being featured by #nature twice in the same issue! ๐Ÿ˜€๐Ÿ‘‡๐Ÿ‘‡๐Ÿ‘‡. The first is a comment of ours titled "To safely deploy generative AI in health care, models must be open source". Details can be seen here:.
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@BoWang87
Bo Wang
11 months
Biologist collaborator : What visualization method should I use now? Everyone says UMAP is bad. Me: every visualization method is misleading, but some are usefulโ€ฆ. Biologist Collaborator: can you just tell me which one to use? . Me: โ€ฆ. Biologist Collaborator: can you create.
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@BoWang87
Bo Wang
1 year
Absolutely! Iโ€™ve seen it happen three times in my lab in the last year: We post our papers as preprints and share our codes on GitHub early, but then others slightly modify our work and get published first. Meanwhile, our papers languish in long review processes. To add insult to.
@Pdorrestein1
Pieter Dorrestein
1 year
@J_my_sci It depends. I personally prefer to preprint but we have noticed some labs repeating our experiments by monitoring our preprints. This is starting to happen to other labs as well as publishing can take months to years after submission while other journals it can take days.
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@BoWang87
Bo Wang
2 years
It's clear we need a visualization method for genomic data analysis that prioritizes reliability and honesty over aesthetic appeal. While tSNE and UMAP may yield visually pleasing results, a more truthful representation of the data's distribution should be the focus.
@slavov_n
Prof. Nikolai Slavov
2 years
This toy example may change how you look at tSNE & UMAP. They find clusters in the most uniform data possible.
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@BoWang87
Bo Wang
10 months
This study reveals something fascinating: Different packages (e.g., in terms of versions and programming languages) of the same algorithms/pipelines can lead to varied results in downstream analysis. Here are my thoughts:. Firstly, this should not be used to critique Seurat and.
@lpachter
Lior Pachter
10 months
The choice of whether to use Seurat or Scanpy for single-cell RNA-seq analysis typically comes down to a preference of R vs. Python. But do they produce the same results? In w/ @Josephmrich et al. we take a close look. The results are ๐Ÿ‘€ 1/๐Ÿงต
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@BoWang87
Bo Wang
1 year
Summary of 2023:.______________________________________________________. Without any doubt, 2023 is the year of LLMs/Generative AI. As a researcher in #AIforHealth and #AIforBiology, 2023 has been a GREAT year for me and the lab! Today is the perfect moment to reflect on our
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@BoWang87
Bo Wang
1 year
Our BLEEP is accepted by #NeurIPS2023 ! Congratulations to the team @RonaldXie1 @garybader1 ! BLEEP is ground-breaking because it finds predictive powers from the H&E images to gene expressions in spatial single-cell data! @VectorInst @UofTCompSci @UofT_LMP @DonnellyCentre.
@BoWang87
Bo Wang
2 years
๐Ÿ”ฌCan whole-slide Hematoxylin and eosin (H&E) stained histology images predict gene expression profiles in single-cell spatial omics? #spatial #SingleCell. Introduce our latest paper, BLEEP (Bi-modaL Embedding for Expression Prediction): a state-of-the-art tool predicting spatial
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@BoWang87
Bo Wang
3 months
๐Ÿ“ข Exciting news! Our preprint on OncoGAN, a novel pipeline for synthetic tumor genome generation using GANs and Tabular VAEs, is now live ๐Ÿงฌโœจ. ๐Ÿง  OncoGAN models eight tumor types, generating unlimited samples that mimic mutation patterns, tumor heterogeneity, and mutational
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@BoWang87
Bo Wang
10 months
AI & Biology/medicine is at its best time ๐Ÿ”ฅ๐Ÿ”ฅexciting time ahead!.
@BowTiedBiotech
BowTiedBiotech ๐Ÿงช๐Ÿ”ฌ๐Ÿงฌ
10 months
๐Ÿค–๐ŸงฌTechbio deals with biopharma and $NVDA
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@BoWang87
Bo Wang
10 months
Thanks @naturemethods for highlighting our work! Cell segmentation is moving forward fast @rita_strack ๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ™Œ๐Ÿ™Œ.
@naturemethods
Nature Methods
10 months
Is cell segmentation a solved problem? Maybe not yet, but the results of this multimodality cell segmentation challenge get us closer! (Spoiler, the winner is a generalist Transformer-based model). @BoWang87
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@BoWang87
Bo Wang
2 years
(1/4) Our BIONIC is finally published in @naturemethods (! Huge congrats to Duncan who really pulled this work off! Great teamwork with my amazing colleagues @garybader1 and Charlie Boone! @PMunkCardiacCtr @VectorInst @UofT_TCAIREM @LMP_UofT @UofTCompSci.
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@BoWang87
Bo Wang
1 year
Exciting news! Our MedSAM is featured in Computer Vision News! ๐ŸŽ‰๐ŸŽ‰๐ŸŽ‰๐Ÿ™Œ. Check it out: We are not stopping at papers and aiming to take integration to the next level by incorporating MedSAM with 3D Slicer, a top-tier medical imaging viewer. ๐Ÿฅ. **Segment
@BoWang87
Bo Wang
1 year
๐ŸŽ‰ The best way to start the week is to find out that our MedSAM is finally published today in Nature Communications!. **Segment anything in medical images** .Paper: arXiv: Data & Code: MedSAM is the first
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@BoWang87
Bo Wang
11 months
Due to numerous requests, I'm providing unrestricted (no paywall), view-only access to the paper through this SharedIt link: Appreciate the support!. PS: to avoid the slightest possibility of confusion, scGPT is unrelated to UMAP; it is not a.
@BoWang87
Bo Wang
11 months
๐Ÿ”ฌ Exciting News! Our manuscript, "scGPT: toward building a foundation model for single-cell multi-omics using generative AI" is now finally published in Nature Methods (@NatureMethods) ๐ŸŽ‰ !!! . (Re-)Introducing scGPT: A transformative foundation model engineered for single-cell
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@BoWang87
Bo Wang
8 months
Sometimes it takes 3-5 yearsโ€™ hard work and significant luck to publish in Nature; sometimes it takes an argument over X to publish in Nature ๐Ÿ˜‚
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@BoWang87
Bo Wang
4 years
I am truly honored to become a Temerty Professor in AI Research and Education in Medicine! Look forward to working with clinicians and data scientists within TCAREM to advance education and research for the next generation of AI-in-medicine researchers!.
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@BoWang87
Bo Wang
2 years
Very honored to be awarded with Gairdner Early Career Investigator Award! #AI is really changing the landscape of biology, particularly single-cell analysis! Thanks for the recognition from @GairdnerAwards! Excited to meet with this year's Gairdner Laureates and discuss science!.
@GairdnerAwards
Gairdner Foundation
2 years
Dr. Bo Wang (@BoWang87) from @VectorInst was one of two winners selected by Drs. John Dick and Stuart Orkin. Dr. Wang was selected for his work on machine learningโ€“based approaches to development trajectories of hematopoietic #StemCells.
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@BoWang87
Bo Wang
3 years
(1/6) Extremely happy to finally publish our OCAT paper! OCAT is a fast and scalable scRNA-seq integration tool that preserves biological variations while being robust to heterogenous data compared to state-of-the-art methods, such as Seurat, Harmony, and Scanorama.
@GenomeBiology
Genome Biology
3 years
OCAT: One Cell At a Time, from Wang, Zhang & @BoWang87, a machine learning method for integrating and analyzing single-cell RNA-seq data from multiple sources. It does not require explicit batch correction, and gives cell feature representations.
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@BoWang87
Bo Wang
12 days
Thrilled that โ€˜Foundation Models for Biologyโ€™ has been named one of the top 7 technologies to watch by @Nature! Thanks for highlighting our scGPT work! Also honored to contribute to such a visionary piece. 2025 will be an exciting year for AI & biology!
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@BoWang87
Bo Wang
3 years
(1/5) I usually don't Twitter about preprints, but this one is an exception since I am extremely excited about it. We present DeepVelo ( ), a deep learning velocity estimation tool for scRNA-seq.
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@BoWang87
Bo Wang
1 year
๐€๐ญ๐ญ๐ž๐ง๐ญ๐ข๐จ๐ง, ๐š๐ฅ๐ฅ ๐ญ๐ก๐ž ๐˜ผ๐™„&๐›๐ข๐จ๐ข๐ฆ๐š๐ ๐ข๐ง๐  ๐ž๐ง๐ญ๐ก๐ฎ๐ฌ๐ข๐š๐ฌ๐ญ๐ฌ! . ๐Ÿ”ฌ Thrilled to introduce our #๐๐ž๐ฎ๐ซ๐ˆ๐๐’๐Ÿ๐Ÿ ๐œ๐ž๐ฅ๐ฅ ๐ฌ๐ž๐ ๐ฆ๐ž๐ง๐ญ๐š๐ญ๐ข๐จ๐ง ๐œ๐ก๐š๐ฅ๐ฅ๐ž๐ง๐ ๐ž ๐ฌ๐ฎ๐ฆ๐ฆ๐ž๐ซ๐ฒ ๐ฉ๐š๐ฉ๐ž๐ซ(see ! Cell segmentation is pivotal in
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@BoWang87
Bo Wang
1 year
Thrilled to share that our MedSAM has been featured in the Nature Communications Editorsโ€™ Highlights. This recognition places MedSAM among the top 50 recently published papers in the field of AI and machine learningโ€”a true honor! ๐ŸŒŸ MedSAM is the first.
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@BoWang87
Bo Wang
11 months
Excited to see the @nytimes article featuring some recent line of work on foundation models like our scGPT in single-cell analysis! In my chat with @carlzimmer, we dived into how foundation models like scGPT are helpful in advancing the development of โ€œvirtual cells.โ€. So, whatโ€™s.
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@BoWang87
Bo Wang
10 months
(1/4) Great to see so much interest from the community regarding AI applications for cell segmentation. First of all, Image segmentation has been an active area of research for over half a century, evolving from heuristic methods and model-based approaches to deep learning
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@BoWang87
Bo Wang
10 months
(1/5) Attention, Cellular Imaging Enthusiasts! . Thrilled to share that our Analysis "The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions" has been published in Nature Methods (@NatureMethods) ๐ŸŽ‰๐ŸŽ‰๐ŸŽ‰ . Cell segmentation is a critical component of
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@BoWang87
Bo Wang
2 years
LLMs (e.g., chatGPT) have huge potential in healthcare, but they are limited without specific training in medical domains. Here we present Clinical Camel (, one of the first open-source medical language models. TLDR, see the chatbot's self-introduction!
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@BoWang87
Bo Wang
2 years
Revolutionizing modern chemistry and drug discovery, #GNN focuses mostly on single graph representations. Yet, the study of multiple graphs (e.g., drugs) interacting under specific conditions (e.g., cell lines) remains less explored. We present CongFu: Conditional Graph Fusion
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@BoWang87
Bo Wang
1 year
When talking about the positive impacts of AI, healthcare and drug discovery always top the list! They're what drives me to get up and make a difference every day. It's an exciting time to be alive!!.
@tsarnick
Tsarathustra
1 year
Geoffrey Hinton: 200,000 people a year die of incorrect medical diagnoses in the United States. AI will fix that in the next 10 years.
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@BoWang87
Bo Wang
10 months
The partnership between Nvidia and leading biotech and pharmaceutical companies brings together cutting-edge computing with vast biological knowledge and data. Recognizing the unique challenges that differentiate the fields of biology from languages, I am wondering: What else do.
@BoWang87
Bo Wang
10 months
AI & Biology/medicine is at its best time ๐Ÿ”ฅ๐Ÿ”ฅexciting time ahead!.
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@BoWang87
Bo Wang
11 months
Just to set the record straight, I'm not a UMAP-hater. I believe that both 2D and 3D visualizations are incredibly effective for conveying biological concepts and presenting data to audiences. I acknowledge the limitations inherent in all visualization techniques. Rather than.
@BoWang87
Bo Wang
11 months
Biologist collaborator : What visualization method should I use now? Everyone says UMAP is bad. Me: every visualization method is misleading, but some are usefulโ€ฆ. Biologist Collaborator: can you just tell me which one to use? . Me: โ€ฆ. Biologist Collaborator: can you create.
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@BoWang87
Bo Wang
1 year
Border agent: what are you coming to the US for?.Me: Attend a conference.BA: about what?.Me: AI.BA: what type of AI?.Me: Generative AI like chat-GPT.BA: do you know why openAI board fired their CEO? so much drama. Me: I really don't know tbh. BA: what is your best guess? Do they.
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@BoWang87
Bo Wang
3 months
๐Ÿงฌ๐Ÿš€ AI-first biology is hitting its stride, and itโ€™s exhilarating to witness!. A great read from @nathanbenaich at weekend: In just five years, weโ€™ve gone from isolated models to generative AI thatโ€™s transforming biology from the ground up. With scGPT,.
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@BoWang87
Bo Wang
1 year
Heading to #NeurIPS23 with two papers presented by my students and me:. 1. BLEEP, a pioneering transformer-based model linking H&E images to gene expression in spatial omics. This is a work led by my PhD student, Ronald Xie (@RonaldXie1 ). Paper: .Code:.
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@BoWang87
Bo Wang
9 months
(2/3) The first challenge is about using AI to detect and then correct medical errors. We've developed an innovative method to detect and correct specific medical errors in clinical notes, achieving top results in all three subtasks. ๐Ÿฉบ๐Ÿ” Key to our success? Utilizing the DSPy
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@BoWang87
Bo Wang
9 months
Thanks @AIatMeta for properly putting our clinical camel on the map of medical LLMs. We are proud to be one of the earliest open-source medical LLMs, laying the groundwork for many of the subsequent, more advanced LLMs in the field of medicine. More exciting development of
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@AIatMeta
AI at Meta
9 months
Researchers at @ICepfl & @YaleMed teamed up to build Meditron, an LLM suite for low-resource medical settings. With Llama 3, their new model outperforms most open models in its parameter class on benchmarks like MedQA & MedMCQA. More details โžก๏ธ
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@BoWang87
Bo Wang
11 months
What is the likelihood of this happening: . P(doom) = P( author i did not read the paper)^ 5 * P( reviewer j did not read the paper) ^ (2 or 3) * P(editor did not read the paper) * P( journal proofreading staff did not read the paper) . And yet it still happened ๐Ÿ˜‚๐Ÿ˜…
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@BoWang87
Bo Wang
11 months
The structure of the Arc Institute is fundamentally designed for success: significant investment attracts a team of world-class scientists, encompassing both wet-lab and dry-lab experts. By ensuring ample funding and providing robust computing infrastructure, it empowers these.
@Prof_Oak_
Professor Oak
11 months
Arc Institute has been on fire recently. LLM innovation, multiple new gene editing tools, bridgeRNA discovery / elucidation, and more, all in the past few weeks. Really encouraged to see a new academic research funding model proving out, and doing so very soon after inception.
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@BoWang87
Bo Wang
4 months
Why RNA Foundation Models?. While protein language models have hit their peak with recent Nobel prize recogitions and DNA language models are getting crowded and messy, RNA models hold unique importance for several reasons:. 1. Predicting mRNA properties is important for.
@BoWang87
Bo Wang
4 months
๐Ÿš€ We're thrilled to introduce Orthrus ๐Ÿงฌ๐Ÿ•โ€”a groundbreaking mature RNA foundation model designed to push the boundaries of RNA property prediction!. ๐Ÿ”ฌ What is Orthrus? .Orthrus is a Mamba-based RNA foundation model, pre-trained using a novel self-supervised contrastive learning
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@BoWang87
Bo Wang
2 months
This is an exciting milestone for our MEDSAM! ๐ŸŽ‰ Our paper "Segment Anything in Medical Images" has surpassed 1,000 citations! . Grateful to the amazing community advancing medical image analysis. This work introduced the first promptable medical image segmentation foundation
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@BoWang87
Bo Wang
7 months
Are foundation models all you need for computational pathology?. The recent benchmark paper from Gabriele et al. gave a comprehensive on the existing pathology foundation models on two series of downstream tasks: disease diagnoses and computation biomarkers. here are the.
@richardjchen
Richard J. Chen
7 months
Excellent work from Gabrielle Campanella, @ThomasFuchsAI @IcahnMountSinai! Benchmarking 8 pathology foundation models including UNI, Virchow and Prov-GigaPath on large scale datasets for clinical diagnosis and biomarker discovery and providing insights into data scaling laws and
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@BoWang87
Bo Wang
9 months
Hold my coffee โ˜•๏ธ๐Ÿ˜‚.
@david_van_dijk
Van Dijk Lab
9 months
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@BoWang87
Bo Wang
6 months
Our review paper on transformers in single-cell analysis @naturemethods is out! Great collaboration with @fabian_theis โ€˜s group! Congratulations to all the co-authors and particularly shoutout to @arturszalata for his leadership in this project! . More details can be seen ๐Ÿ‘‡.
@arturszalata
Artur Szaล‚ata
6 months
Thrilled to share @fabian_theis lab paper on transformers in single cell omics out in @naturemethods ! Check it out to learn about the latest models, how they are trained, applied, and their limitations. (๐Ÿงต1/7).
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@BoWang87
Bo Wang
1 year
Some personal predictions of the #AIforScience landscape in 2024 ๐Ÿš€:. 1.Expect a rise in non-transformer-based foundation models, like Mamba. 2.Genomic LLMs will gain traction in Pharma for drug discovery and genomic data analysis. 3.Medical LLMs will revolutionize.
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@BoWang87
Bo Wang
7 months
It looks like LSTM is making a comeback! This recent paper shows that simply replacing the Mamba module in our U-Mamba with xLSTM can improve medical segmentation performance. Currently, we're working on integrating Mamba-2 into U-Mamba and will update you on which architecture.
@HochreiterSepp
Sepp Hochreiter
7 months
Our new xLSTM performs well in vision: and Better than Transformer and Mamba. More applications with xLSTM will come soon.
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@BoWang87
Bo Wang
1 year
** ๐™๐™ฃ๐™ซ๐™š๐™ž๐™ก๐™ž๐™ฃ๐™œ ๐™ฉ๐™๐™š ๐™‹๐™ค๐™ฌ๐™š๐™ง ๐™ค๐™› #๐˜ผ๐™„ ๐™ž๐™ฃ ๐™๐™ง๐™–๐™ฃ๐™จ๐™ฅ๐™ก๐™–๐™ฃ๐™ฉ๐™–๐™ฉ๐™ž๐™ค๐™ฃ** . Excited to announce our recent publication in #NatureComm titled: โ€œA machine-learning approach to human ex vivo lung perfusion predicts transplantation outcomes and promotes organ
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@BoWang87
Bo Wang
10 months
โ€œThe next big game-changing revolution is in biology.โ€ . Cannot agree more!. We are at a pivotal moment where vast amounts of biological data are being generated, and large-scale models are increasingly accessible for analyzing omics and sequences. Thereโ€™s truly no better time.
@ericschmidt
Eric Schmidt
10 months
Biotech is just about to happen at a new and much faster scale !.
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@BoWang87
Bo Wang
3 years
(1/4)Is image segmentation a solved problem by #AI? maybe for natural images,but hardly true for cell segmentation! To address the gap, we announce the cell seg competition () in multi-modal high-resolution microscopy images in #NeurIPS2022.Join us and RT!.
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@BoWang87
Bo Wang
2 years
๐ŸŽ‰Big cheers for Emily So, an exceptionally talented master student co-supervised by Benjamin (@bhaibeka) and myself, on publishing her first first-authored paper in @NatureMachIntell! TL;DR:. AI models in healthcare are flourishing, but the issue of.
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@BoWang87
Bo Wang
1 year
Thrilled to announce that Trevor, a first-year undergrad @UWaterloo and our summer intern at @UHN, clinched 2nd place in the 2023 "A Tumor and Liver Automatic Segmentation (ATLAS)" Challenge! ๐ŸŽ‰ (see During his time in our lab, he crafted a DL pipeline
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@BoWang87
Bo Wang
2 years
Massive thanks to everyone for supporting our clinical camel! In just a week since going live, we've seen an amazing response worldwide. We're clocking an average of 5000+ daily users on our live demo with over 90% of thumbs-up! - that's incredible! So thrilled to see the.
@BoWang87
Bo Wang
2 years
(Re-)Introducing #ClinicalCamel ๐Ÿช: an innovative open-source conversational #LLM engineered specifically for healthcare: . Paper: Model weights in HF: Eval Scripts at Github: Live Demo:
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@BoWang87
Bo Wang
8 months
Our fourth speaker, @AI4Pathology from @harvardmed , is talking about recent foundation models in pathology! The workshop is so popular that we even have a line outside of the room .
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@BoWang87
Bo Wang
8 months
Third talk is about using LLMs to do biomedical parsing, delivered by Dr. Mu Wei from @Microsoft !
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@BoWang87
Bo Wang
1 year
AI & Biology ๐Ÿงฌ ๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ”ฅ.
@sethbannon
Seth Bannon
1 year
"Where do I think the next amazing revolution is going to come? And this is going to be flat out one of the biggest ones ever. There's no question that digital biology is going to be it.". Jensen Huang, founder & CEO of NVIDIA.
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@BoWang87
Bo Wang
11 months
Wow huge congratulations! AI & biology is really on fire ๐Ÿ”ฅ.
@czbiohub
Chan Zuckerberg Biohub Network
11 months
The CZ Biohub Network is pleased to welcome the biomedical & AI expertise of 3 new members to our Board of Directors: .๐ŸŒŸSam Altman/@sama, @OpenAI CEO.๐ŸŒŸSam Hawgood, @UCSF Chancellor .๐ŸŒŸMike Schroepfer/@schrep, Partner @Gigascale. View the full Board: .
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@BoWang87
Bo Wang
1 year
Please tune in and it should be fun! Thanks for inviting @Cornell @WeillCornell.
@WCM_AIDH
WCM Institute of AI for Digital Health
1 year
We are thrilled to have Dr. Bo Wang (@BoWang87) talking about biomedical foundation models in our February seminar. Register here to hear Dr. Wangโ€™s amazing work.
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@BoWang87
Bo Wang
1 year
#DiffusionModels have revolutionized generative AI, particularly in nature imagery. But how about medical images?. Our recent #MICCAI2023 paper, "Pre-trained Diffusion Models for Plug-and-Play Medical Image Enhancement", addresses it. Medical image enhancements often rely on.
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@BoWang87
Bo Wang
11 months
Very thrilled to witness Toronto General Hospital at @UHN secure a top 3 global ranking! This outstanding accomplishment fills us with pride, especially knowing our AI innovation in lung transplantation played a pivotal role in achieving this success!Congratulations!.
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@BoWang87
Bo Wang
2 months
Our perspective of how to build the #AI virtual cell is out in @CellCellPress ! This is an amazing vision led by @cziscience ! . Now it is time to get the work started! #scGPT ๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ”ฅ.
@EricTopol
Eric Topol
2 months
Towards the #AI virtual cell, which would represent one the most extraordinary achievements in life science.@CellCellPress @StephenQuake @czi @cziscience @_bunnech
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@BoWang87
Bo Wang
3 months
Honored to give the keynote for the Bigelow Lecture Series by @UofT Surgery @uoftmedicine! Discussed how generative AI can transform healthcare with our labโ€™s projects: Clinical Camel, MedSAM, and scGPT. Grateful for the amazing turnout from surgeons and trainees. Inspired by
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@BoWang87
Bo Wang
11 months
This seems out of control ๐Ÿ™ˆ๐Ÿ™ˆ
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@BoWang87
Bo Wang
11 months
What is the likelihood of this happening: . P(doom) = P( author i did not read the paper)^ 5 * P( reviewer j did not read the paper) ^ (2 or 3) * P(editor did not read the paper) * P( journal proofreading staff did not read the paper) . And yet it still happened ๐Ÿ˜‚๐Ÿ˜…
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@BoWang87
Bo Wang
2 years
Grateful to @globeandmail for featuring our progress in #AI for #singlecell analysis. A round of applause for @garybader1's outstanding leadership in orchestrating and guiding numerous extensive cell atlas projects! @UofT_TCAIREM @UofTCompSci @UofT_LMP @DonnellyCentre.
@globeandmail
The Globe and Mail
2 years
Scientists and AI are on a quest to map every cell in the human body, charting where and why disease happens
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@BoWang87
Bo Wang
1 year
Late to the discussion, but I always value insights from @mo_lotfollahi! ๐Ÿš€ Great seeing more evaluation papers on foundation models. Check out this recent one from other group too: While any comments I make about scGPT should be taken with a pinch of.
@mo_lotfollahi
Mo Lotfollahi
1 year
(1) This is an amazing paper on the limitations of (current) single-cell foundation models "Our results indicate that both Geneformer and scGPT exhibit limited reliability in zero-shot settings and often underperform compared to simpler methods.".
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@BoWang87
Bo Wang
9 months
Thanks for the shoutout @UofTCompSci ! Congratulations to all the award recipients!.
@UofTCompSci
U of T Department of Computer Science
9 months
U of T AI researchers Amir-massoud Farahmand, Gennady Pekhimenko and Bo Wang are recent recipients of Ontario Early Researcher Awards for projects on reinforcement learning; computer systems; and deep learning tools for heart failure prediction.
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