Amar Sahay
@AmarSahay_
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Professor @harvardmed & MGH. Engineering strategies to enhance cognition since 2011. Dad. Husband. Marathoner. đŠ Diver. Also at https://t.co/WOlBKYMhir
Boston, MA
Joined July 2016
Unbelievable! Gracias âŠ@carlosalcarazâ© for taking the picture! Vamos! âŠ@Wimbledonâ© Defending Champion.
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@eperlste 1. Your tweet about reviewer disagreements & reproducibility. Academia is evolving & BTW despite flaws, peer reviewed science continues to generate incredible value in biotech via IP & startups. 2. Industry is more competitive? What? Discovery and drug dev are both damn hard
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@eperlste Excuse me. I read your tweets. I found them defensive and suggestive of academia as a failure. I am trying to reason with you here before you alienate biotech and academia. If you agree with my position then there is nothing to disagree.
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@eperlste 2/2 My suspicion is that all large institutions suffer from bloat, academia and pharma (vs biotech). But Disabling the machine rather than fixing it (a re-negotiated IDC w/ full transparency on both sides) will be very damaging to all stakeholders.
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@elonmusk lets now also see more transparency behind IDC calculations. On both sides. For real debate.
To be clear, what the @DOGE team and @USTreasury have jointly agreed makes sense is the following: - Require that all outgoing government payments have a payment categorization code, which is necessary in order to pass financial audits. This is frequently left blank, making audits almost impossible. - All payments must also include a rationale for the payment in the comment field, which is currently left blank. Importantly, we are not yet applying ANY judgment to this rationale, but simply requiring that SOME attempt be made to explain the payment more than NOTHING! - The DO-NOT-PAY list of entities known to be fraudulent or people who are dead or are probable fronts for terrorist organizations or do not match Congressional appropriations must actually be implemented and not ignored. Also, it can currently take up to a year to get on this list, which is far too long. This list should be updated at least weekly, if not daily. The above super obvious and necessary changes are being implemented by existing, long-time career government employees, not anyone from @DOGE. It is ridiculous that these changes didnât exist already! Yesterday, I was told that there are currently over $100B/year of entitlements payments to individuals with no SSN or even a temporary ID number. If accurate, this is extremely suspicious. When I asked if anyone at Treasury had a rough guess for what percentage of that number is unequivocal and obvious fraud, the consensus in the room was about half, so $50B/year or $1B/week!! This is utterly insane and must be addressed immediately.
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100%. Renegotiate IDCs, more transparency at both ends.âIf the issue is that people donât want the government to fund research, well then donât fund grants at all. Funding them, demanding that grantees do the work theyâve said they will, and then not paying for it is bullshit.â
âWhy donât universities pay research costs with their endowmentsâ is a bad argument. Grants arenât charity. These are contracts where universities are being paid to carry out work on behalf of the public. Why shouldnât the government be expected to pay the full cost of the work being done on their behalf? Universities shouldnât get everything they ask for - the government should absolutely only pay legitimate expenses, and I would fully support any effort to make sure that is happening. And many university endowments are absurd, and the push to accumulate large endowments has poisoned universities. If the government doesnât like how much money theyâre sitting on, they can tax them. But donât ruin science to punish rich universities. If the issue is that people donât want the government to fund biomedical research, well then donât fund grants at all. Funding them, demanding that grantees do the work theyâve said they will, and then not paying for it is bullshit.
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@AdrianoAguzzi Hilarious, applies everywhere. I no longer go out of my way to engage with people who only look out for their interests. There are many people out there with whom that time is better spent:)
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RT @DavidPepper: Q: Can people do anything right now to safeguard against the risks? What should be done going forward? A: âThe current âwâŠ
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RT @srikosuri: Itâs been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendrâŠ
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@melcregor Lol or âhow orange neurons enhance intelligence the mostâ or why people in glass houses shouldnt throw stones when stoned (Aim 1) or on ketamine (Aim 2)
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RT @DrPhiltill: Hmm. There are two errors in this, and also the new 15% limit is way too low. And finally this is an unintentional call forâŠ
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RT @GaryMarcus: I retired from the American University system at age 49 (after 26 years) so have no direct stake in this. But am here to sâŠ
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1. Cost/footprint basis for pharma >academia. 2. Medical centers, medical schools & medical institutions do not have similar size endowments like universities (Harvard U is not same as MGH or HMS). 3. I cant use my direct cost for my lab to pay for IDC. Renegotiate IDC. @DOGE
Can you believe that universities with tens of billions in endowments were siphoning off 60% of research award money for âoverheadâ? What a ripoff!
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@tedcruz @FoxNews @elonmusk This reduction of IDC will be crippling. Re-negotiate. Medical Schools and Hospitals dont have endowments. Red or Blue: Diseases dont care. We have the best biomedical enterprise, a source of hope for all of us.
Someone might consider reminding Texas senators and congresspersons how much money the MD Anderson Cancer Center got from the NIH last year, and that their overhead rate is 62%. @MDAndersonNews
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@TangleNews @FoxNews @joerogan This is very very very damaging to our biomedical research, the best in the world and the source of new therapeutics for brain diseases and cancers and it will receive bipartisan opposition. Do the Math. Renegotiate IDC!
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Indirect costs or IDCs can be re-negotiated rather than abruptly and drastically reduced to 15%. This will profoundly constrict the drug discovery pipeline for brain diseases and cancer. Academics & Industry folks Agree. Raise the cap, do the Math @DOGE @elonmusk
Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead, what is known as âindirect costs.â Today, NIH lowered the maximum indirect cost rate research institutions can charge the government to 15%, above what many major foundations allow and much lower than the 60%+ that some institutions charge the government today. This change will save more than $4B a year effective immediately.
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