Andrew Octavian Sasmita
@AOSasmita
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Postdoc @YvonneMNolan @AnatNeuroUCC š¬š§ PhD @KlausNave @MPI_NAT | Alzheimer's x glia x sex differences x microbiome | (he/they) š³ļøāš
Cork, Ireland
Joined March 2022
Are you using 5xFAD mice to study Alzheimerās disease? Our work @NeuroCellPress may be relevant to you š Age and sex are known to influence AĪ² plaque burden in these mice. Here, we found that the transgene parentage is another strong determinant. (1/11)
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Microglial cGAS Deletion Preserves Intercellular Communication and Alleviates Amyloid-Ī²-Induced Pathogenesis of Alzheimer's Disease
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RT @SamuelBHume: This is like AlphaFold, but for protein localisation rather than folding It's a deep learning model that predicts a proteā¦
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RT @braincomms: Gentreau et al. report that statin use is linked to higher white matter hyperintensity volumes and lower grey matter volumeā¦
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RT @MasudHusain: Older ApoE female Īµ4 carriers show greater cognitive decline, but younger female homozygous Īµ4 carriers actually have a coā¦
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RT @LukensJohnR: Reducing microglial lipid load enhances Ī² amyloid phagocytosis in an Alzheimerās disease mouse model | Science Advances htā¦
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RT @DaniBeckman: In hard times like now, I hope scientists and society can continue together. This is a human neuron from a 94-YO man withā¦
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RT @ISMND1: Dr. Inhee Mook-Jung will be our next ISMND webinar speaker! Title: Bypassing the BBB? The role of vagus nerves in the transmisā¦
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RT @MolNeuro: 'Cellular #senescence induced by #cholesterol accumulation is mediated by #lysosomal #ABCA1 in #APOE4 and AD' Shaowei Wang,ā¦
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RT @EricTopol: Our gut microbiome and its metabolites have key interactions with our immune response to cancer and success from cancer immuā¦
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Great coverage of our new study by @DrShaena from @_TheTransmitter āØ
In a popular Alzheimerās disease mouse model, mice that inherit disease-related variants from their fathers have double the amyloid beta plaques seen in those with maternal inheritance, a new study shows. By @DrShaena
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RT @Roisin_McManus_: I am thrilled to share our latest article that has been published in @ImmunityCP. We describe a new role for NLRP3 outā¦
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RT @AlbertPol10: What are 26 different Rab GTPases doing on Lipid Droplets? Are lipids transferred by membrane contact sites? Moving the FAā¦
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RT @EricTopol: Precise 3D Imaging of the gut-brain axis in the Alzheimer's disease model @ScienceAdvances open-accā¦
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RT @DaniBeckman: Blood vessel in the brain for #FluorescenceFriday! Major components of the 'blood-brain barrier' are in this photo. This 'ā¦
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RT @ErikMusiek: This narrative that the amyloid hypothesis is a hoax based on a disgraced 2006 paper and has distracted us from the "real"ā¦
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Interesting systematic review on comorbid Alzheimerās disease and multiple sclerosis focusing on reported cases in the past 5 years.
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For #FluorescenceFriday, a side-by-side comparison of 5xFAD hemibrains at 6 months showing how AĪ² plaques can be modulated not just by sex but also by the transgene parentage. More details from our recent paper where we reported the transgene inheritance effect in 5xFAD mice š
Are you using 5xFAD mice to study Alzheimerās disease? Our work @NeuroCellPress may be relevant to you š Age and sex are known to influence AĪ² plaque burden in these mice. Here, we found that the transgene parentage is another strong determinant. (1/11)
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RT @erturklab: See our recent @NatureBiotech study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseenā¦
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