Zain Munir Patel
@zafateniac
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Postdoctoral fellow at Harvard Med, Mass Gen Hospital and Broad with Luca Pinello. Ph.D. from UofT in Molecular Genetics with Tim Hughes
Joined September 2009
Happy to get this work out. We developed CRISPR-CLEAR to dissect enhancers at nucleotide resolution with some nice implications for CAR-T cell therapy. Work co-led with @BasheerBecerra & @SWittibschlager under the supervision of @lucapinello, @DSeruggia and @danielevanbauer
First pre-print from the lab! Together with @lucapinello and @danielevanbauer we developed CRISPR-CLEAR, an experimental and computational pipeline to dissect enhancers at nucleotide resolution.
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RT @srikosuri: It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendr…
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@MazMHussain Interesting paper recently from AI safety researchers on gradual disempowerment of humans due to AI development.
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RT @halfacrocodile: A brief reminder: the IBIS conference is going to happen on Nov 27 = today (or tomorrow, depending on your timezone). G…
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RT @hsnajafabadi: Super excited to finally share the results of a massive effort with @ProfTimHughes to characterize the intrinsic sequence…
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RT @halfacrocodile: (1/13) Excited to present the results of the large-scale benchmarking of DNA motif discovery tools using the Codebook d…
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@michael_nielsen Don’t remember the quote from skunk works but just reading about the test pilots blew my mind. Tom Wolfe really captures it well in the Right Stuff! The risk tolerance of these pilots was off the charts.
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RT @hsnajafabadi: Super excited to finally post about our RNA foundation model, led by our very own Ali Saberi (not on Twitter), with @geno…
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RT @quaidmorris: 💥💥💥New preprint 💥💥💥on the EuPRI resource. Where we reconstruct the motifs for 34,736 RBPs and study their function and evo…
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RT @halfacrocodile: Glad to see this beast out in the wild, incredible collab. with @CarldeBoerPhD's lab on modeling promoter sequences wit…
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Okay this made me emotional. One of the greatest athletes of all time. It was a pleasure to watch all those matches.
Mil gracias a todos Many thanks to all Merci beaucoup à tous Grazie mille à tutti 谢谢大家 شكرا لكم جميعا תודה לכולכם Obrigado a todos Vielen Dank euch allen Tack alla Хвала свима Gràcies a tots
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RT @dominickmatthew: Timelapse flying by Hurricane Milton about 2 hours ago. 1/6400 sec exposure, 14mm, ISO 500, 0.5 sec interval, 30fps…
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RT @JSheltzer: Another scientist whose work initially didn't get the recognition that it deserved - Victor Ambros was denied tenure at Harv…
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Honestly this was amazing! Maybe one of my fav podcast episodes of all time.
Episode w @dylan522p and @asianometry out! A bonanza on how the semiconductor industry actually works. & what Xi could do if he becomes scaling pilled, how we can train models with 10,000x GPT-4's compute by end of decade, & much more. This one is very fun. Enjoy! Links below. 0:00:00 – Xi’s path to AGI 0:05:05 – Liang Mong Song 0:09:10 – How semiconductors get better 0:12:01 – China can centralize compute 0:19:35 – Export controls & sanctions 0:33:45 – Huawei’s intense culture 0:39:45 – Why the semiconductor industry is so stratified 0:41:50 – N2 should not exist 0:46:47 – Taiwan invasion hypothetical 0:50:15 – Mind-boggling complexity of semiconductors 1:00:06 – Chip architecture design 1:05:29 – Architectures lead to different AI models? China vs. US 1:11:06 – Being head of compute at an AI lab 1:17:17 – Scaling costs and power demand 1:37:59 – Are we financing an AI bubble?
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RT @pkoo562: Excited that CREME (Cis-Regulatory Element Model Explanations) is published in @NatureGenet! Work led by @ToneyanSh! tl;dr CR…
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RT @GallowayLabMIT: Nifty! A relatively small reduction in CD19 rescues cells from aCD19-CAR-T. Interesting for understanding antigen escap…
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RT @UrnovFyodor: This is phenomenal. The initial collaboration between @danielevanbauer and yours truly used the kernel of this approach to…
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And wanted to thank others including Ana Kutschat, @justindelano_ ,Eric Che, Ting Wu, Marlena Starrs, Martin Jankowiak and others.
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