Carl de Boer
@CarldeBoerPhD
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Assistant professor @BME_UBC studying eukaryotic gene regulation (cis-regulatory logic); amateur mycologist; parent; he/him/his Find me @carldeboer.bsky.social
Vancouver, BC, Canada
Joined September 2011
Made the move to bluesky... @ Giving it a shot as the experience on x has been increasingly dissatisfying. Keeping this account for now, but don't expect to engage me on x any time soon.
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New (and hotly anticipated - at least by me) preprint from my group describing a better way to partition training data for genomic-trained models to solve the long-neglected problem of homology-based data leakage. Thread from first author @muntakim_rafi 👇
0/ Essential reading for anyone training or using sequence-function models trained on genomic sequences! 🚨 In our new preprint, we explore the ways homology within genomes can cause leakage when training sequence-based models and ways to prevent it
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RT @muntakim_rafi: 0/ Essential reading for anyone training or using sequence-function models trained on genomic sequences! 🚨 In our new pr…
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@VK_Ulaganathan Certainly it is much more appreciated amongst complex disease geneticists. We give some examples in the paper but please let us know if there is anything we missed. Audience is mainly genetics-adjacent.
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RT @biorxiv_genomic: Variant effects depend on polygenic background: experimental, clinical, and evolutionary implications
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Great opportunity to gain experience with perturb-seq experiments and analysis in iPSC lung models. Joint PD with @nika_shakiba
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RT @KipoiZoo: Join us for the next Kipoi Seminar with with Abdul Muntakim Rafi (Rafi) @muntakim_rafi @CarldeBoerPhD @UBC! 👉Detecting and a…
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Interested in sequence-based gene regulation models? Updated tweetorial for the final version of the paper describing the Random Promoter DREAM Challenge 2022, wherein we make field-leading cis-regulatory models.
1/If you're training ML models on DNA sequences, u need to take a look at our new paper in @NatureBiotech! It contains analysis done by over 300 researchers, tells the story of how we built state-of-the-art for short regulatory DNA and developed a framework to keep improving
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RT @NatureBiotech: A community effort to optimize sequence-based deep learning models of gene regulation https://t.…
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RT @SBME_UBC: Join our vibrant, collaborative community. SBME is hiring an Assistant Professor of Teaching (tenure track) in the Education…
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