Vincent Weisser
@vincentweisser
Followers
18K
Following
259K
Media
574
Statuses
9K
cofounder/ceo @primeintellect 🤖 decentralized agi + science 🔬 co-initiator @bioprotocol @vita_dao / lets solve death
sf 🌁
Joined December 2011
Today, we release TOPLOC:. A hashing scheme for verifiable inference that detects modifications, works across setups, validates 100× faster, and cuts proof memory by 1000×. Building the foundations for peer to peer compute + superintelligence.
Today, we release TOPLOC: A Locality Sensitive Hashing Scheme for Verifiable Inference. - Detects modifications to models, prompts, or precision.- Robust across GPU types, tensor parallel configurations and attention kernels.- Up to 100× faster validation than generation.-
6
11
83
.@ilyasut full talk at neurips 2024 "pre-training as we know it will end" and what comes next is superintelligence: agentic, reasons, understands and is self aware
84
780
3K
Peter Thiel making the case for open source, decentralized AI. "The real AI risk is a totalitarian world government. Global compute governance would be very heavy-handed, creating a dystopian one-world nanny-state government.".
53
109
805
TIL there was a literal "Thinking Machines Corporation" in the 80s. With Richard Feynman, Marvin Minsky, Stephen Wolfram and other legends involved.
31
37
577
"What is your 10 year plan, and why can't you do it in 6 months?" - Thiel.
19
27
458
We've completed the first decentralized training of a 10B model!! . Trained across the US, Europe, and Asia 🌐. Full release coming in a week including base model, checkpoints, post-trained model and data.
We did it — the first decentralized training of a 10B model is complete!. Trained across the US, Europe, and Asia 🌐. Post-training with @arcee_ai is underway, and a full open-source release is coming in ~1 week, including: base model, checkpoints, post-trained model and data.
35
37
450
“There is nothing in biology yet found that indicates the inevitability of death. This suggests to me that it is not at all inevitable and that it is only a matter of time before biologists discover what it is that is causing us the trouble.”. — Richard P. Feynman.
20
53
435
We are open-sourcing INTELLECT-1, the first decentralized trained 10B model. Including base model, checkpoints, post-trained model, data, technical report and our decentralized training framework.
Releasing INTELLECT-1: We’re open-sourcing the first decentralized trained 10B model:. - INTELLECT-1 base model & intermediate checkpoints.- Pre-training dataset.- Post-trained instruct models by @arcee_ai.- PRIME training framework.- Technical paper with all details
15
38
351
Got my O1 visa stamped! 🇺🇸 . Huge thanks to @plymouthstreet, @lisawehden, and everyone who wrote recommendation letters for me. See you all in SF soon! 🫡
53
4
332
Decentralized science summarized by @balajis. - on-chain citation path.- meta-data of every experiment for accuracy (stored on-chain, enables reproducibility) eg. @lab_dao.- truly open access, permanent decentralized storage.- funding eg. @Molecule_dao.
12
61
323
Intellect-1 is successfully training across the world. Amazing to see the broader community contribute compute to truly decentralized and open source AI.
11
35
286
@MichaelTrazzi what concretely lies ahead? imo most likely outcome is that compounding capital will be highly relevant post agi/asi.
1
1
262
Decentralized science is now represented on thanks to @samonchain proposing and helping on this. Feel free to make a pull request and lets improve this page together:
10
60
225
Exciting milestone with @vita_dao to have $4m+ more to fund more longevity research! 🧬. Getting @pfizer ventures, @balajis, @ShineCapitalNYC, @L1Digital_, @beakerdao, @SpaceshipDAO, @bettslacroix and many more onboard! 🧑🔬
🤩 We are excited to announce that we've closed a $4.1m fundraising round🌱 from strategic members including:. • @pfizer Ventures.• @ShineCapitalNYC.• @L1Digital_.• @beakerdao.• @SpaceshipDAO.• @balajis.• @bettslacroix.and many more. 🧵.
16
19
222
A big day for decentralized science! After over two years of building infrastructure for permissionless research, @bioprotocol launches today. Bio accelerates science by empowering communities to collectively fund, develop, incubate, and own scientific research. It began with.
The next iterations of our scientific institutions will run on crypto rails
32
29
216
Today, @johannes_hage and I are excited to introduce @primeintellect – democratizing AI development at scale, from compute to intelligence. We’ve raised $5.5m, led by @DistributedG @Coinfund_io @CompoundVC, @Collab_Currency @ProtocolLabs @ClementDelangue @dylan522p and others.
Introducing Prime Intellect – democratizing AI development at scale, from compute to intelligence. We're excited to announce our $5.5M raise from @DistributedG @coinfund_io @CompoundVC @Collab_Currency @protocollabs @ClementDelangue @dylan522p and others
29
20
203
.@ilyasut full talk at neurips 2024 "pre-training as we know it will end" and what comes next is superintelligence: agentic, reasons, understands and is self aware
0
9
199
decentralized ai + science is just getting started. autonomously accelerating science
24
24
195
entering the intelligence age of planetary-scale computation
We did it — the first decentralized training of a 10B model is complete!. Trained across the US, Europe, and Asia 🌐. Post-training with @arcee_ai is underway, and a full open-source release is coming in ~1 week, including: base model, checkpoints, post-trained model and data.
8
20
197
AGI is progressing. Next major milestone may be long-horizon autonomous agents—including AI scientists—capable of independent, extended decision-making and research.
We announced @OpenAI o1 just 3 months ago. Today, we announced o3. We have every reason to believe this trajectory will continue.
6
23
196
We released a metagenomic foundation model to help detect and prevent the next pandemic early! 🫡. Open-source, decentralized AI can help differentially accelerate scientific progress to safeguard against risks like pandemics while deepening our understanding of nature.
Releasing METAGENE-1: In collaboration with researchers from USC, we're open-sourcing a state-of-the-art 7B parameter Metagenomic Foundation Model. Enabling planetary-scale pathogen detection and reducing the risk of pandemics in the age of exponential biology.
17
22
198
Decentralized science is just getting started.
The community of the DAO.Decentralized autonomous organizations are growing as alternative research funding models, but are also strong scientific communities. We should get on board
8
27
188
.@VitalikButerin sharing his ideas on decentralized science, longevity, public goods funding, ai and scientific progress broadly.
4
42
190
Kicking off the first ever decentralized training at 10b scale! 🫡.
Announcing INTELLECT-1: the first-ever decentralized training of a 10B model. Scaling decentralized training 10x beyond prior efforts. Anyone can join us to build open-source AGI 🦋
15
14
191
If you want to learn more about decentralized science, a few great starting points:. Excellent explainer by @juanbenet .
9
41
159
.@bioprotocol is building the foundation for citizen science — empowering individuals to incubate, fund and commercialize biotech research. From longevity and neuro to cryopreservation, psychedelics, synbio, women's health, rare diseases, hair loss, long COVID, quantum bio, and.
So what is BIO?. BIO is a launchpad and liquidity protocol for BioDAOs. Financial rails for the next generation of citizen science, allowing biotech to be funded and commercialized by individuals instead of institutions. > 8 BioDAOs launched to date.> $40m+ in tokenized IP.>
7
27
152
revenue acceleration ~4.4x monthly growth. glad to help reduce compute spend for an increasing amount of ai devs and startups through the cheapest compute 🫡
11
6
155
We've successfully closed ~$2.8M (1,108 ETH) for cryopreservation research together with @kaimicahmills, @emilkendziorra, @elimohamad and a fantastic community of scientists and cryo enthusiasts.
What a ride! 🥶. CryoDAO has successfully closed a monumental ~$2.8M fundraise (1,108 ETH) on Juicebox!. CryoDAO's goal is to solve death by funding, incubating and advancing cryopreservation research 👉
8
14
142
Looking to hire a Chief of Staff + COO at @primeintellect interested to work on decentralized AI — smart, hungry, AI-native. Ideally with prior startup ops and AI experience + SF based. Message me or apply here.
7
19
144
Decentralized Science is happening 🧑🔬🧪. Thanks so much for the @Molecule_dao @vita_dao @PsyDAO_ shoutout @pierskicks @RaoulGMI!! 🙏. Big fan of @RealVision!
11
22
136
Jensen bullish on decentralized training "Distributed training will have to work . distributed computing will be invented . some some form of federated learning . async distributed computing is going to be discovered, and I am every enthusiastic and optimistic about that".
BG2. Ep 17. Double $NVDA! System Level Comp Moat, “Insane Demand”, Inference Explosion 1 B x, Memphis Supercluster, OpenAI, & more. @altcap @_clarktang @bgurley. (00:00) Intro. (1:50) The Evolution of AGI and Personal Assistants. (06:03) NVIDIA's
11
22
137
Times new roman AI mafia
A little torn that my greatest contribution to tech might be bringing back 1997-style times new roman websites.
2
9
134
Incredibly excited for the next chapter of @Molecule_dao enabled by our $12.7m seed round led by @npv_vc!. is an open platform that links bio-medical researchers to funding in order to enable more therapeutics to reach patients.
16
17
127
Love @balajis idea of a dashboard showing potential network states like @PraxisSociety @CityDAO (other promising ones?) aggregating the cryptographically audited censuses: number of community members, acreage of real estate, community’s on-chain income etc. Anyone building this?
9
17
126
Looking forward to interviewing Vitalik about his thoughts on decentralized science and science in general. What questions would you like to ask him?.
🚨CALLING THE DESCI ECOSYSTEM🚨. @VitalikButerin will be joining us via zoom for DeSci London to share his thoughts on #DeSci, what questions would you like to ask him?. Comment below 👇
23
11
129
Great introduction to d/acc (defensive / decentralization / democracy / differential acc) by @VitalikButerin
Introduction to D/ACC. @VitalikButerin shared his insights on d/acc (defensive / decentralization / differential acc) — an approach to tech advancement focused on building resilient technology. Watch the full talk, including Q&A, here:.
7
15
128
Join us at NeurIPS to discuss decentralized training and to discuss the path towards open-source AGI!. 📍Vancouver, Saturday, December 14, 5+8:00 PM .
7
15
119
Some of the biggest challenges facing science according to 270 researchers, and how we can fix them potentially with decentralized science 🧑🔬. 1. Academia has a huge money problem 🫰.Use funding models like @vita_dao to provide more stable, long-term funding for scientists,
10
38
112
Inspiring to see the flourishing and progress of so many novel scientific efforts .- - .- .- - . And across DeSci
2
18
109
You want to get started into longevity and could benefit from a small grant to visit a conference, join or something else. Ping me with how much money you need (up to $3k) and how you would use it.
4
33
105
.@lab_dao is building an execution layer for the life sciences, enabling everyone to plug into powerful bioinformatics and labs, and collectively building this protocol 🧑🔬🧪. One of the most exciting communities and protocols to accelerate scientific progress🌿
4
12
108
Deepseek completely mogging the closed ai labs. Creating a state of the art model for $5.6m.
> $5.5M for Sonnet tier.it's unsurprising that they're proud of it, but it sure feels like they're rubbing it in. «$100M runs, huh? 30.84M H100-hours on 405B, yeah? Half-witted Western hacks, your silicon is wasted on you, your thoughts wouldn't reduce loss of your own models»
6
4
106
Decentralized and truly open AI is coming. @colinraffel beautifully making the case for decentralized ai!. An ecosystem of specialist models would likely be dramatically more efficient and effective than big models like GPT-4 on many measures.
6
13
101
Excellent essay, relevant in the current Q* discussion, by @finbarrtimbers (ex DeepMind). "Greedy sampling is the worst form of sampling, except all those other forms that have been tried from time to time." - Winston Churchill, if he worked in NLP". (h/t
3
4
105
H200s landed on
7
9
103
Asimov once called Robert McCall the "nearest thing to an artist in residence from outer-space."
4
12
98
@cz_binance Check out Decentralized science and biotech: DeSci Wiki, covering almost every project.
5
10
91
decentralized training.around the world
Releasing INTELLECT-1: We’re open-sourcing the first decentralized trained 10B model:. - INTELLECT-1 base model & intermediate checkpoints.- Pre-training dataset.- Post-trained instruct models by @arcee_ai.- PRIME training framework.- Technical paper with all details
12
5
94
Layer 0 "ideology layer" by @balajis: "we need to code laws faster than they can outlaw code"
0
10
89
Really excited for the upcoming open and decentralized science quadratic donation round with Gitcoin. Grateful to @VitalikButerin @juanbenet @protocollabs @StefanDGeorge @SCRForum @Molecule_dao (and hopefully more soon) for supporting with generous matching donations. True MVPs.
In GR15, there are four cause rounds: Climate Solutions, Crypto Advocacy, DEI (Diversity, Equity & Inclusion), and [NEW!] DeSci (Decentralized Science). Stay tuned for round eligibility criteria and available matching funds!.
5
16
89
@paulg Check out IP-NFTs, that we use to fund longevity research with @vita_dao enabled by @Molecule_dao .
2
12
88
Anything missing for this definition of fully open source AI?.- code accessibility: source code, training data, and pre-trained weights are openly available. - licensing: permissive licenses like apache 2.0, MIT, or GPL allowing unrestricted use, modification, and distribution.
The definition is pretty clear cut if you ask @vincentweisser . “Vincent Weisser the founder of Prime Intellect, an AI lab based in San Francisco, would prefer if the model were made “fully open on every dimension””. @TheEconomist
11
10
89
In SF for the next two months - ping me if you wanna chat scientific foundation models, ai alignment, longevity, applied metascience etc.! 🌁.
7
3
88
You can just start a hero run with 256 H100s on-demand on
5
8
85
We are making science autonomous with @PrimeIntellect @vita_dao @Molecule_dao @bio_xyz and many other amazing builders in decentralized science + AI!.
A Blueprint for Breakthroughs:. Our latest piece on DeSci <> AI where we deep dive into how this ultimate collab will revolutionise the entire medical industry. Here's a guide to how it's gonna play out 👇
2
9
83
Let's work towards making the proposed crypto-powered ARPA (Advanced Research Projects Agency) by @juanbenet a reality this year!. @Molecule_dao @foresightinst @protocollabs @hypercerts @lab_dao @vita_dao @bio_xyz @DeSciLabs @ResearchHub @uselateral . collaborating on this🧑🔬
9
16
83
Decentralized science is exploding. The Ethereum page and DeSci wiki getting outdated. Seeing dozens of new DeSci projects pop up in the Gitcoin DeSci round. Feel free to add 🙏.
8
17
81
Open source AI is catching up quickly. DeepSeek-V3 seems to be on-par/better than Claude, 4o etc on many benchmarks. Trained with much less compute.
🚀 Introducing DeepSeek-V3!. Biggest leap forward yet:.⚡ 60 tokens/second (3x faster than V2!).💪 Enhanced capabilities.🛠 API compatibility intact.🌍 Fully open-source models & papers. 🐋 1/n
8
3
82
New nanogpt speedrun record breaking 3min — just ~3 days after the last record we supported! . Amazing to see this continued progress in open-source. And excited @PrimeIntellect could support this incredible research🫡
Sub 3-minute NanoGPT Speedrun Record. We're proud to share that we've just breached the 3 min mark!. This means that with an ephemeral pod of 8xH100s that costs $8/hour, training a GPT-2-ish level model now only costs $0.40!. ---. What's in the latest record? A 🧵.
4
4
82
"Three monumental pillars looming on the horizon:.- limitless clean energy.- artificial superintelligence.- radical life extension. These aspirations seem disparate at first glance, yet they represent interconnected threads in the tapestry of our cosmic future. When viewed.
5
8
77
What are the most impressive ai knowledge tools that you've seen?. Big fan of obvious ones like . (@elicitorg).(@omniscience42). which ones am i missing?.
10
13
76
A landmark moment for network states! 🏴. Exciting to see the flourishing of so many network state initiatives. Check out and by @vita_dao 💛.
Here's the livestream for the Network State Conference (part 1 of 2).
1
9
76
Awesome event by binance + @bioprotocol discussing decentralized science and ai with Vitalik, CZ and many other amazing builders.
Learning at a small gathering of DeSci entrepreneurs organized by Labs.
4
6
76
First longevity biotech startup spinout from @vita_dao in collaboration with the amazing Vera Gorbunova and her lab 🧑🔬🥳. Matrix is leveraging the anti-cancer and pro-longevity effects of high molecular weight hyaluronic acid from naked mole rat to human 🐀.
🤯 VitaDAO becomes the FIRST DAO to 🌱 kickstart a BIOTECH company, MatrixBio. 🔬🧬. MatrixBio explores hyaluronic acid-based compounds, aiming to pioneer in cancer and aging treatments, utilizing insights from cancer-resistant naked mole rats 🐀. 🧵.
2
6
74
Ending death has the potential to become the most meaningful and unifying cause for humanity.
Ending death.
4
14
73
bio/acc: accelerating open, decentralized citizen science.
> scientist does science.> cures cancer.> the science™️: “no no, you can’t do that”. and then you wonder why most scientists are fleeing academia
9
9
71
We are working collaboratively on a page to explain decentralized science on . Feel free to take a read and suggest improvements .
8
17
69
From sparse, centralized to dense, decentralized networks. Power dynamics shift as networks decentralize.
3
7
72
.@cryodao community has crowdfunded a super exciting cryopreservation moonshot research project (within one day with $900k). focused on high sub-zero preservation and revival of a small mammal, led by the amazing @aschwindewolf
5
10
71
can u feel the acceleration, anon?.
Announcing INTELLECT-1: the first-ever decentralized training of a 10B model. Scaling decentralized training 10x beyond prior efforts. Anyone can join us to build open-source AGI 🦋
4
2
67
@ClementDelangue @ylecun @elonmusk We clearly need both, and nothing moves the world forward as much as scientists paired with entrepreneurs translating and bringing the research to market.
1
2
66
We are hiring! Join us fixing science funding at @Molecule_dao 🧑🔬🧪. - VP of Ops.- VP of Marketing.- UI Designer.- Head of Ventures. Read more here: If you have question ping @EzanneTess @paulkhls or me
9
18
68
Using crypto to crowdfund scientific quantum research ⚛️. 0.5 ETH needed to get this kicked off .
9
9
68
Assessing GPT-4's Role in Advancing Scientific Discovery:. An Excellent Study of Its Knowledge, Understanding, Numerical Calculations, and Predictive Abilities in Science.
8
5
69
Exciting to talk about Decentralized AGI at @MIT Decentralized AI Roundtable. Making the case for decentralized AI, exploring opportunities, addressing risks, and outlining research paths.
5
12
69
Decentralized science is applied meta- and open science . 🌐 A truly digital and open alternative to the current scientific system.⛓️ Using crypto-architecture and economics .🧑🔬 For ideation, collaboration, running experiments, funding, sharing data etc.
1
16
64
Excellent essay by James Brodie about decentralized science and biotech.
1
14
66
Decentralized training accelerating further! Great work by Nous on Distro/Demo. Excited to dive deeper, experiment with it, and integrate it into our framework as we collectively scale decentralized training 🫡.
Nous Research announces the pre-training of a 15B parameter language model over the internet, using Nous DisTrO and heterogeneous hardware contributed by our partners at @Oracle, @LambdaAPI, @NorthernDataGrp, @CrusoeCloud, and the Andromeda Cluster. This run presents a loss
1
7
67
Ilya is clearly among those most deeply involved on the frontier of AI and alignment, co-leading super-alignment. What concerns were significant enough to drive him to take this action?.
5
4
66
Decentralized training is the path forward in the inference-time compute paradigm that enabled o1. Our first release by @MatternJustus in this direction to effectively scale reasoning.
Today, we are releasing:. - INTELLECT-MATH, a frontier 7B parameter model for math reasoning.- The largest synthetic math dataset to date of 5M verified reasoning traces.- An outlook on decentralized training in the inference-compute paradigm.
7
7
66
If you are planning a decentralized science meetup and need a small sponsor of $0,2-1k - ping me. And if you wanna support global desci meetups and conferences, donate here .
13
9
65
@RyanSAdams - ImpactDAOs, DeSci, Refi: - Web2 integrating web3.- GameFi .- Broadening of NFTs to research (IP-NFTs), music, video and other verticals.- More pro and noob friendly defi.- Social crypto (next level on top of lens, POAP etc.).
3
3
62
Get a bounty discussing the different @longevityprize hypothesis prize winners and submissions from last year . (cc @ResearchHub).
3
9
63
Excited to introduce OpenDiLoCo - big step towards making decentralized training more accessible by our team reproducing, scaling and open sourcing DeepMinds research.
Introducing OpenDiLoCo, an open-source implementation and scaling of DeepMind’s Distributed Low-Communication (DiLoCo) method, enabling globally distributed AI model training.
2
10
64
Join my talk about decentralized science at @EthCC: . "Why DeSci? The purpose and impact of decentralized science" 🧑🔬. July 18th, 3:35 pm - 4:00 pm.Eiffel Stage.
4
11
65
Who is coming to #EthAmsterdam? 🇳🇱 . Excited for DeSci Amsterdam (@descieth), @gitcoin Schelling Point, @TheDAOist_ and much more.
14
6
64
We're launching Fast Compute Grants to support ambitious open-source AI research. Apply here:
We're launching Fast Compute Grants to support ambitious open-source AI research into novel models, architectures, techniques, and paradigms needed to make open and decentralized AGI a reality.
5
8
61