Twan Lammers
@twan_lammers
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Professor of Nanomedicine @RWTH | Past President @CRSScience | Council @ESMI_society | Editor @JCRnEDITORS | Science🧪 | Sports⚽️ | Traveling🌍 | People🧑🤝🧑
Maaseik, Belgium
Joined June 2022
Postdoc, PhD and Technician positions available @UniklinikAachen and @RWTH. Join our diverse and dynamic team to work on translational aspects of cancer nanomedicine and nano-immunotherapy. Projects funded by @dfg_public and @ERC_Research. Contact via email or DM. Pls retweet 🙏
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Biomarkers are needed to improve cancer nanomedicine clinical translation. Check out our work on identification of tumor tissue / biopsy biomarkers in @natBME . Thanks @AstraZeneca @IMC_Prague @LaBOORatory @UniklinikAachen @RWTH @dfg_public @ERC_Research.
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Insightful viewpoint on Cancer Nanomedicine in @NatureRevCancer. Reflection on achievements and challenges, and outlook to the future. Sangeeta Bhatia (@snbhatia), Xiaoyuan Chen, Marina Dobrovolskaia, and @twan_lammers. See
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Grateful and honored to be recognized with the 2022 JNB Trailblazer Award from @JNanobiotech, together with @WeiboCai. For details, see
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Las Vegas and Paris were great, in many regards. The people and science at #CRS2023 were oustanding, and I even managed to see my student-time hero @JerrySeinfeld. Next #CRS2024 will be in BOLOGNA 🇮🇹, JULY 8-12. Please mark your agenda and make sure to be there @CRSScience
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Out now in @natrevbioeng. EPR Effect vs. ATR Principle. How do nanoparticles accumulate in tumors? Not surprisingly, the answer is “it depends”. On the intrinsic leakiness of the tumor and on the type of nanoparticle used. Check out the full comment👇.
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How do bivalent #COVID #RNA #vaccines 🦠 connect to the next frontier in #nanomedicine? What can we learn from the clinical multidrug nano-products Copaxone and Vyxeos? How to combine 3 drugs in 1 nanoparticle? Check out this perspective in @NatureNano 👉
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Hard work and dedication pay off. Over the past 5 years, the @CRSScience journal Drug Delivery and Translational Research @DDTReMedia has impressively increased its quality and impact (new IF = 5.7). Thumbs up for @MariaJ_Alonso and the editorial team 👍🏾👍🏻👍
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Cool study coming out soon in @JCRnEDITORS, looking at collagen deposition and TME effects on drug delivery in multidrug-resistant breast cancer. Congrats to first-author team Okan, Asmaa and Karina👍. Thanks @IMC_Prague for the collaboration🙏.
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“Clinical translation of gold nanoparticles” 🥇 First paper by Rui Zhang @RWTH, in @DDTReMedia. Concise and up to date overview of all therapeutic gold nanoformultions in clinical trials. @CRS_FG_NANO @ESMI_SG_IGDD
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Does nanomedicine have a delivery problem?. How to improve cancer nanomedicine clinical translation? . Many informative video recordings out now on @YouTube from #Clinam2023👇. Thanks @FedericaDeLore3 @JanNiklasMay1 @AshfordFell for contributions.
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I correctly guessed the question! But I couldn’t believe the #CRS2023 award talk would be about this. Waw, @JustinHanesPhD, that was amazing! Life lessons, things to think about, and a lecture not to be forgotten. My favorite was a bonus answer: “The secret of living is giving”👌
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Enjoying #SFB2023 @SFBiomaterials. Getting ready for #CRS2023 @CRSScience. And brainstorming about #CRS2024 with @pgdecuzzi 🎬🧠🇮🇹
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The tumor accumulation of antibodies is less than 1%. This does not prevent antibodies and ADCs from inhibiting tumor growth and creating clinical impact!. Why do people in #nanomedicine worry about 0.7%?. Excellent @ESMI_society award lecture by Prof. Liesbeth de Vries!
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Two “papers of the month” in 1 week🥇🥇. Brilliant job by @JanNiklasMay1 and Chris Hark from @UniklinikAachen @RWTH, as part of #RTG2375 @dfg_public . Both papers are available open access @DDTReMedia @natBME 👇.
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Check out our up-to-date overview of nanoparticle formulations used in the clinic or in clinical trials for diagnostic and theranostic purposes 🧪 ⚗️ 🧑🔬 🩻 ☢️ in @JournalofNucMed. @ESMI_SG_IGDD @CRS_FG_NANO 👇
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Outstanding PhD thesis and oral defense by our Maharaja of Microbubbles. Dr. @Anshu_Dasgupta 👑🔉🫧👨🏽🎓. Exemplifies the original and impactful work done @UniklinikAachen @RWTH in the @dfg_public project #RTG2375 on tumor-targeted drug delivery 🎯 . New PhD positions opening soon
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We are looking for outstanding doctoral research and researchers in drug delivery science 💊🦠🧑🔬🧫 💉. Thesis awards come with many benefits. See website for details. Nominate yourself or a colleague. Pls retweet🙏. @CRSScience @ESMI_society @JCRnEDITORS @ADDReditors @DDTReMedia
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Full house of friends - at 8 am YSC standard time - for the truly brilliant @CRS_YSC Exceptional Leadership Award lecture of Dr. Sara Cordeiro 👌. @asaracordeiro @dmuleicester @CRSScience #CRS2024
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Very happy to see that @RWTH is among the leading universities in Germany (#2) and Europe (#4) in innovation in the @Clarivate ranking. Beautiful city 🌆, closely connected to beautiful neighboring countries 🇳🇱🇧🇪🇫🇷, and lots of exciting science + entrepreneurship ongoing 💪
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Pleased to see this out. Great work by @Anshu_Dasgupta on active targeting of shape-optimized microbubbles to brain endothelium. Many thanks @SMitragotri for co-leading this and all others for support🙏. #RTG2375 @UniklinikAachen @RWTH @CRSScience
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We are live - in person - at the Paris hotel in Las Vegas. #CRS2023 starts with a full-day Biologics Summit, co-organized by @CRSScience and @IPECAMER. Many thanks to @MatooriSimon, Beate Bittner, Ron Smith and Nigel Langley for putting together an outstanding program 👌
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Nonspherical ultrasound microbubbles .🔊🫧. Many thanks to @Rob_Palomba and @pgdecuzzi for margination analysis, to @FUSLab for ultrasound guidance and to many local collaborators @UniklinikAachen and @RWTH. Led by @Anshu_Dasgupta @_taosun_ @SMitragotri 👉
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Clean and lean new study in Small @AdvSciNews: Intermittent Fasting improves Tumor-Targeted Drug Delivery and Nanotherapy Treatment Efficacy 🥗🎯.#RTG2375 @DFG__Official @ERC_Research @RWTH @UniklinikAachen . Available open access👇.
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Happy and proud to be one of the grantees😊. Great to see 3 @RWTH @UniklinikAachen #DWI proposals in the selection. Congrats @rkramann and Andreas Herrmann💪. Thanks @ERC_Research for the support🙏
📣The results of the second round of ERC Proof of Concept Grant call are out. 66 researchers are to receive €150k each to explore commercial or societal potential of the results of their research projects. Read more:👉 #ERCPoC #FrontierResearch
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Interested in Image-guided Drug Delivery? . 🦠🔬☢️💊🔉🫧🧬. Check out 24 (!) high-quality papers and 2 insightsful editorials in 2 theme issues in @ADDReditors👇. and make sure to attend the IGDD sessions @ESMI_society in Porto and @CRSScience in Bologna
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Brilliant lecture by @SMitragotri on the fundamentals and challenges of targeted drug delivery 🎯, and on the potential of DDS engagement with cells 🧫. “A hitchhiker’s guide to drug delivery”. Thanks @ChenYBecky for putting together a great session on @CRSScience at #wbc2024
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Become a CRS member for FREE ✅. Are you passionate about drug delivery research, but unable to cover the membership fee? Then check out our new Sponsored Membership Program👇. Several sponsors have already signed up. Apply today to profit from their generosity!. Pls retweet 🙏
Learn more about the CRS Sponsored Membership Program!.More info: 👉 Interested in becoming a sponsor for our Sponsored Membership Program? Click the link above to visit our website for more information and sponsorship details. #crs #deliveryscience
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Enjoying day 1 of the @CrsIndian @CRSScience LC meeting in Mumbai 🇮🇳. Over 400 highly interested and engaged attendees, excellent speakers, and several well-deserved recognitions, incl. the Lifetime Achievement Award for Prof. N. Udupa. Outstanding hospitality and organization👌
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Comprehensive overview of nanoparticle imaging agents. With lots of details on their production, characterization, application and translation. Thanks @DavidCormode for magnificently leading this👌 .
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Very well deserved gold medal award winner🥇: Dr. Jason Lewis @LewisLabMSKCC @WMISWMIC #WMIC2022. Many congrats🥂
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Turning 50 today: Fabian Kiessling from @RWTH and @UniklinikAachen 🎉🎂. Still the same looks as at age 40, at @WMISWMIC and @ESMI_society in Dublin 🏍🤘. Featured in Nature Communications and for a change fighting balloons instead of boxers 🥊😜
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Check out the 40 Years Anniversary Issue of JCR / @JCRnEDITORS . Quality and quantity (978 pages!) of authors and contributions are amazing👌. Highlights include a masterpiece by Prof. Jindrich Kopecek and orations by @AnaBeloqui1 and @GormleyLab . 👉
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Five great pieces of advice for writing a great scientific paper ✍️🧑💻🖼️ : .1 - Start with why. 2 - Keep it simple. 3 - Pictures are 1000 words. 4 - Details matter. 5 - Failure is key to success. Check out the full text and details for free in @JCRnEDITORS 👇.
[Editorial] Lessons learned from a decade as an editor of scientific journals. By Christine Allen @ChristineAllenW .[50 days' free access].
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Very happy to announce this worked out well! Five more years of funding for #RTG2375 for 24 more PhD/MD students @RWTH @UniklinikAachen ✌️🙏.
Warming up 😅 and chilling out 😎 for a big grant evaluation tomorrow. 5k run and 50k gravel ride along La Meuse. Lowest tides in ages. Included several strategic site visits to ensure a smooth and successful outcome 🤞🤞🤞
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How many PhD students do you know who have co-conceived, supervised and senior-authored a Q1 peer-reviewed research paper?. @JanNiklasMay1 💪
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New PhD position available at @RWTH and @UniklinikAachen. Focus is on the development and testing of metal (pro)drugs and nanomedicines for cancer immunotherapy. Pls retweet 🙏. @CRSScience @CRS_FG_Immuno .@ESMI_society @ESMI_SG_IGDD .@CRS_GermanChapt @CRSBeNeLuxFr
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Pleased and proud to see our perspective being received so well 😊. We describe smart - i.e. rational and realistic - strategies to promote cancer nanomedicine translation and exploitation. @rvdmnanomeds @ESulheim @Yang_Shi_1 @Kiessling_F @WillemNANO
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Summarizing 10+ years of efforts to promote the clinical translation of core-crosslinked polymeric micelles. @ADDReditors @JCRnEDITORS @UUPharmaceutics @SFB_DD_SIG @ESMI_SG_IGDD .
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Very well-deserved recognition for former JCR editors Kinam Park from @PurdueBME and Wim Hennink from @UUPharmaceutics 🏆 @JCRnEDITORS
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Targeting neutrophils in sepsis with RGD-modified liposomal dexamethasone 🦠. Excellent first paper by MD student Ritvik Mathur from @UniklinikAachen @RWTH . Work performed within the framework of our @dfg_public funded doctoral training network #RTG2375.
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Brilliant perspective on #MOF biomedical applications by Alec Wang, Madeline Walden, Quim Pena et al. Concise, comprehensive and contemplative! Thanks @wuttkescience @Gassensmith @Kiessling_F for contributing. Available open access in AFM👇.
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Very well-deserved recognition for Hamid Ghandehari @H_Ghandehari from @PHCEUutah for having done a tremendous job as editor-in-chief of Advanced Drug Delivery Reviews @ADDReditors. Check out and be part of the upcoming Emerging Voices 🎤 theme issue:
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Important new work in @AdvSciNews. On mRNA transfection in tumor vs endothelial cells upon the use of microbubbles and ultrasound 🧬🔉🫧. #RTG2375 @dfg_public .
I congratulate Junlin Chen and co-workers to a new paper that was just published in Advanced Science about the use of ultrasound and microbubbles for mRNA delivery to tumors: Chen J, et al. Adv Sci doi: 10.1002/advs.202306139. PMID: 38342634.Check it out and enjoy reading!.
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Insightful and inspiring session on ERC funding at #CRS2024. Incl. opening speech by Prof. Maria Leptin + Samyang award lecture by Prof. Maria Vicent. @ERC_Research @CRSScience . @mleptin @pgdecuzzi @AnaBeloqui1 @AviSchroeder @LabMerkel @Prakash_UTwente @A_Wykowska @MariaJVicent1
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Check out this super-exciting virtual symposium coming up in September. Addressing in vitro diagnostics 🧪, robotic delivery 🦾, AI in drug development 💊, etc. Organized by Beate Bittner, @MatooriSimon and @CRSScience. Sponsored by @Roche. Pls retweet 🔄!
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Interested in contributing to the best journal in drug delivery science? Learn about our new aims and directions. And feel free to reach out! @JCRnEDITORS @CRSScience .
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European Society for Molecular Imaging mentors and mentees 2022-2023 meeting up at #emim2023 @ESMI_society
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Check out this very cool conference: “Nanomedicine meets the tumor microenvironment”. Great science and speakers. 🧪🥼🧬. @CRSBeNeLuxFr @CRS_GermanChapt @CRS_FG_NANO @ESMI_SG_IGDD.
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Time to say goodbye to Dr. Ilaria Biancacci @ilaria93_ilaria 👩🏼🎓⚗️🔬. One of our favorite #RTG2375 doctoral researchers. Many thanks for your commitment and engagement. Happy that we will be seeing you again very soon, at our #ExMI lab-out in Egmond aan Zee in May 🌊☀️🏝️
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Dr. Ilaria Biancacci successfully defended her PhD thesis today @RWTH 🎓. With flying colors 🎉. Flawless oral exam, 3 papers published and 2 in prep. In 3.5 years of RTG funding, generously provided by the DFG @dfg_public. Many congrats and enjoy your family holiday in 🇧🇪🇳🇱
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Very much looking forward #CRS2022 @CRSScience, July 11-15, in Montreal. Awesome meeting, much fun, big impact, great topics, fantastic speakers, lovely people.
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Insightful discussion on challenges in nanomedicine clinical translation 🎙️🖥️. Many thanks to @MariaJ_Alonso for moderating and asking the right questions, and to @CSLVifor for hosting and enabling. 👉 See also @DDTReMedia:. 👉
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Part 2 of Xiangyang Bai’s PhD thesis 🎓, on covalently self-assembled nano-, micro- and macromaterials. In press at Advanced Materials. Thanks @Yang_Shi_1 for conceiving and coordinating 👍, and @DeLaporte_Lab and @wuttkescience for collaborating 🙏.
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CRS - Connecting People 💙. @CRSScience . @rvdmnanomeds @MJMitchell_Lab @AviSchroeder . #BeilsteinNanomedicine2024
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Important new paper, by Sarah Schraven et al, showing that different fluorescent dyes have different effects on polymeric nanocarrier biodistribution. Part of #CRC1382 @dfg_public. Another nice collaboration with @MedPolymers_Prg and @IMC_Prague🙏.
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What a great way to start @2024Wbc . Breakfast with former @JCRnEDITORS colleague and closing plenary speaker Prof. Ick Chan Kwon (@DoubleParr). Followed by a wonderful opening plenary lecture by Prof. Nicholas Peppas (@NPeppas). #wbc2024
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Very nice first paper by doctoral researcher Mirjavad Moosavifar from @UniklinikAachen @RWTH . Engineering microbubbles with porous polymeric shells, thereby enhancing their ultrasound imaging and drug delivery capabilities 🔉🫧. Available open access at
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Good morning Haifa! Getting ready for day 1 of the Umbrella Symposium co-organized by @TechnionLive @fz_juelich @RWTH. Strengthening existing partnerships and creating new ones. @ZingerAssaf @AviSchroeder @MachlufLab @santorof14 @vanvanka123 @SachseGroup @neuroccino @LaBOORatory
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Starting in less than 💯 hours: #CRS2022 Plenary lecture 1, by the 1 and only Kinam Park, from @LifeAtPurdue and @JCRnEDITORS. Be there! @CRSScience @CRS_FG_bMimetic @CRS_FG_Gene @CRS_FG_Immuno @CRS_FG_NANO @CRS_FG_Ocular @CRS_FG_Oral @CRS_FG_SkinMuco @CRS_FG_Nervous @CRS_YSC.
Very much looking forward #CRS2022 @CRSScience, July 11-15, in Montreal. Awesome meeting, much fun, big impact, great topics, fantastic speakers, lovely people.
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Much looking forward to the @CRSScience Spain and Portugal local chapter meeting. Impressive lineup of invited speakers, many young scientist talks, and lots of time for social interaction and networking. Thanks @CRS_SPLC for splendid organization👌
In Lisbon, Portugal 🇵🇹ready for the @CRS_SPLC SPLC-CRS 2024 meeting, the XVth meeting of this organization. The @CRSScience President @twan_lammers is also here. My plenary is in 3.5 hours.
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400+ people at the #CRS2023 Translational Science & Entrepreneurship roundtable discussion on #mRNA and #LNP, moderated by @pgdecuzzi and Maria-Teresa Peracchia, featuring @peer_lab, @sahayg, Patrick Baumhof, Roger Pak and Jeewon Joung. @CRSScience
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Very successful @CRS_YSC industry session. Neither seating not standing space available 👍🏻👍👍🏿
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The 2023 Journal Impact Factors have been published today 📚🔖. #JIF #impactfactor #JCR. Great to see the good performance and post-COVID consolidation of our most important nanomedicine, drug delivery, biomaterials and biomedical engineering journals. @CRSScience @SFBiomaterials
Just hours to go until the annual Journal Citation Reports release, when 21,500+ trusted journals will receive a Journal Impact Factor. Is your journal one of the 9,000+ receiving a #JIF for the first time? Join the conversation using #JCR2023 and #TrustedJournals.
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PhD project #25 completed today. Special moment, special number, special person. Congratulations, thumbs up, very well done Dr. Mengjiao Liu 🔉🫧💊
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Very well deserved 🏆 - Close to 1 kg of beautiful images and innovative drug delivery science 👌
Super proud🥹 of @SendersMax! He won the best thesis award from the @ESMI_society.at the #EMIM2023 in Salzburg! . Thank you @ESMI_society for this great honor and @twan_lammers for his beautiful words🙏🏼. Beautiful
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Full house for Khuloud Al-Jamal @aljamal_khuloud from @KingsCollegeLon sharing impressive recent results on SNALP and RNA delivery at #CRS2022
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Looking forward to seeing some Dutchmen 🇳🇱 at #CRS2022 at @Palais_Montreal. Including a unique look at Vincent van Gogh @immersivevango
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CRS PhD thesis award lectures at 6:30 PM in room 710 🏆. Many thanks to a great team of judges for going through 25 impressive theses. And thanks @ElsevierConnect and @JCRnEDITORS for supporting the award 👍. @CRSScience
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Happy and proud to note that our #RTG2375 @dfg_public PhD students @JanNiklasMay1 and @RahafMihyar from #ExMI at @UniklinikAachen @RWTH were recognized with awards for best oral and best poster presentation @CRS_GermanChapt. Thanks @PRC_Heidelberg for organizing a great meeting!.
Two tightly packed days of delivery science are coming to an end. Congratulations to all presenters for their interesting contributions, and to the four awardees! And kudos to everyone who made this meeting possible!.See you in Bologna at @CRSScience or in Bern. Safe travels!
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Summary of the lecture in written form:. …
Our fearless @CRSScience leader @twan_lammers gave a great talk at the @CRS_SPLC meeting in London on Cancer Nanomedicine.
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New 2023/2024 impact factors released 🎖️. Very good news for our @CRSScience journals:. JCR = 10.5 @JCRnEDITORS .DDTR = 5.7 @DDTReMedia .ADDR = 15.2 @ADDReditors . #JIF2023 #JCR2024 @Clarivate.
The 2024 Journal Citation Reports is coming soon! More than 21,800 trusted journals will receive a Journal Impact Factor. Join the conversation using #JCR2024 and #TrustedJournals.
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Congrats to Dr. Maryam Sheybanifard, for completing her PhD 🎓. One of the best doctoral researchers in our #RTG2375 @dfg_public, focusing on Tumor-Targeted Drug Delivery 🎯 @UniklinikAachen @RWTH. Great work on continuous flow manufacturing @LabonaChip. Next stop @AstraZeneca 🇸🇪
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Paper #2 in PhD year #1 for Rui Zhang ✌️. Showcasing the energy, engagement and efficiency of JPI fellows 💪. Thanks Roger Molto Pallares for study design and supervision 👍. @JPhysChem @RWTH @UniklinikAachen
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👇 Timely, comprehensive and complete review in @NatRevNeph on imaging tools and technologies for monitoring chronic kidney disease. Note that CKD will be one the major disease challenges for the 21st century… @DrugTrain_ITN @LaBOORatory @rkramann @ESMI_SG_IGDD #RTG2375 #KFO5011.
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“Polymeric materials for ultrasound imaging and therapy”. Nice new perspective in @ChemicalScience @RoySocChem. Great work Roman Barmin, MirJavad Moosavifar et al @UniklinikAachen @RWTH 👌.
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Join us for #CLINAM next week. Online and in person. In Basel, Oct 8-10, at @Novartis campus. Exciting session on polymeric micelles on Tue, with @LuxenhoferLab @VicentPTLab. Congrats to abstract/poster award winners Shiva, Karina/Paul, @Anshu_Dasgupta 💪.
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Networking in a spectacular environment. Starting at 9 PM Montreal time at #CRS2022. @CRS_YSC @CrsIndian @SouthAfricaCRS @AustralianCRS @CRSBeNeLuxFr @brazilCRS @CC_CRS @CRS_Italia @CRS_GermanChapt @KoreaCRS @CRSMalaysia @CRSNordicLocal @nz_crs @CRS_SPLC @CRS_TW_Local @UKICRS
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Infinitely proud 🥹 @ESMI_society . YIA 🏆 winner 2023 - Asmaa Elshafei.
Asmaa Elshafei wins the #EMIM2023 Young Investigator Award!! Well-deserved, congratulations! It was such an amazing presentation! 🤩🥳
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Fantastic viewpoint by @AthinaAnastasa1 in @angew_chem on “How to obtain an ERC starting grant” 🇪🇺. Valuable description of process and criteria, tips and tricks, and the importance of persistence 💪. Must-read for ambitious PhD students and postdocs 🔎. @ERC_Research @CRS_YSC
My perspective on what matters for an ERC Starting Grant: The art of failing and how persistence (and other factors) ultimately leads to success. @angew_chem @ERC_Research .Link:
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Did you know?. Now in PNAS: “Our immune system consists of 1.8 trillion cells, weighing 1.2 kg. Lymphocytes are 40% of the number and 15% of the mass. Macrophages are 10% of the number and 50% of the mass, because of their large size”. @CRS_FG_Immuno 🦠.
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