How do drug delivery systems 🎯 help to modulate biological barriers and bio-material interactions? With a team of basic scientists 🧑🔬 and clinicians 🧑⚕️, we analyze the state-of-the-art and future directions of interfacial drug delivery. Open access 👉
Postdoc, PhD and Technician positions available
@UniklinikAachen
and
@RWTH
. Join our diverse and dynamic team to work on translational aspects of cancer nanomedicine and nano-immunotherapy. Projects funded by
@dfg_public
and
@ERC_Research
. Contact via email or DM. Pls retweet 🙏
“EPR effect vs. ATR concept” 🎯
Do nanomedicines accumulate in tumors passively or actively?
Is this different in different tumor types, or for soft vs. hard nanoparticles?
How do new targeting mechanisms contribute to clinical impact?
Check out
Insightful viewpoint on Cancer Nanomedicine in
@NatureRevCancer
. Reflection on achievements and challenges, and outlook to the future. Sangeeta Bhatia (
@snbhatia
), Xiaoyuan Chen, Marina Dobrovolskaia, and
@twan_lammers
. See
Las Vegas and Paris were great, in many regards. The people and science at
#CRS2023
were oustanding, and I even managed to see my student-time hero
@JerrySeinfeld
. Next
#CRS2024
will be in BOLOGNA 🇮🇹, JULY 8-12. Please mark your agenda and make sure to be there
@CRSScience
Out now in
@natrevbioeng
EPR Effect vs. ATR Principle
How do nanoparticles accumulate in tumors? Not surprisingly, the answer is “it depends”. On the intrinsic leakiness of the tumor and on the type of nanoparticle used.
Check out the full comment👇
Honored to have received the International Award from the Belgian Society of Pharmaceutical Sciences (BSPS) and proud to be among prominent previous recipients. Finally managed to deliver the accompanying invited lecture at the meeting in Blankenberge 🇧🇪🙏
“Negative results” are rarely published. Even though disproving hypotheses seems as valuable as proving them.
Based on previous work, we explored biophysical tumor priming with tamoxifen and found that there are no beneficial effects on drug delivery👇
How do bivalent
#COVID
#RNA
#vaccines
🦠 connect to the next frontier in
#nanomedicine
? What can we learn from the clinical multidrug nano-products Copaxone and Vyxeos? How to combine 3 drugs in 1 nanoparticle? Check out this perspective in
@NatureNano
👉
Hard work and dedication pay off. Over the past 5 years, the
@CRSScience
journal Drug Delivery and Translational Research
@DDTReMedia
has impressively increased its quality and impact (new IF = 5.7). Thumbs up for
@MariaJ_Alonso
and the editorial team 👍🏾👍🏻👍
Cool study coming out soon in
@JCRnEDITORS
, looking at collagen deposition and TME effects on drug delivery in multidrug-resistant breast cancer. Congrats to first-author team Okan, Asmaa and Karina👍. Thanks
@IMC_Prague
for the collaboration🙏.
“Clinical translation of gold nanoparticles” 🥇 First paper by Rui Zhang
@RWTH
, in
@DDTReMedia
. Concise and up to date overview of all therapeutic gold nanoformultions in clinical trials.
@CRS_FG_NANO
@ESMI_SG_IGDD
I correctly guessed the question! But I couldn’t believe the
#CRS2023
award talk would be about this. Waw,
@JustinHanesPhD
, that was amazing! Life lessons, things to think about, and a lecture not to be forgotten. My favorite was a bonus answer: “The secret of living is giving”👌
The tumor accumulation of antibodies is less than 1%.
This does not prevent antibodies and ADCs from inhibiting tumor growth and creating clinical impact!
Why do people in
#nanomedicine
worry about 0.7%?
Excellent
@ESMI_society
award lecture by Prof. Liesbeth de Vries!
Check out our up-to-date overview of nanoparticle formulations used in the clinic or in clinical trials for diagnostic and theranostic purposes 🧪 ⚗️ 🧑🔬 🩻 ☢️ in
@JournalofNucMed
.
@ESMI_SG_IGDD
@CRS_FG_NANO
👇
Outstanding PhD thesis and oral defense by our Maharaja of Microbubbles
Dr.
@Anshu_Dasgupta
👑🔉🫧👨🏽🎓
Exemplifies the original and impactful work done
@UniklinikAachen
@RWTH
in the
@dfg_public
project
#RTG2375
on tumor-targeted drug delivery 🎯
New PhD positions opening soon
Very happy to see that
@RWTH
is among the leading universities in Germany (
#2
) and Europe (
#4
) in innovation in the
@Clarivate
ranking. Beautiful city 🌆, closely connected to beautiful neighboring countries 🇳🇱🇧🇪🇫🇷, and lots of exciting science + entrepreneurship ongoing 💪
We are live - in person - at the Paris hotel in Las Vegas.
#CRS2023
starts with a full-day Biologics Summit, co-organized by
@CRSScience
and
@IPECAMER
. Many thanks to
@MatooriSimon
, Beate Bittner, Ron Smith and Nigel Langley for putting together an outstanding program 👌
Interested in Image-guided Drug Delivery?
🦠🔬☢️💊🔉🫧🧬
Check out 24 (!) high-quality papers and 2 insightsful editorials in 2 theme issues in
@ADDReditors
👇
and make sure to attend the IGDD sessions
@ESMI_society
in Porto and
@CRSScience
in Bologna
📣The results of the second round of ERC Proof of Concept Grant call are out.
66 researchers are to receive €150k each to explore commercial or societal potential of the results of their research projects.
Read more:👉
#ERCPoC
#FrontierResearch
Brilliant lecture by
@SMitragotri
on the fundamentals and challenges of targeted drug delivery 🎯, and on the potential of DDS engagement with cells 🧫
“A hitchhiker’s guide to drug delivery”
Thanks
@ChenYBecky
for putting together a great session on
@CRSScience
at
#wbc2024
Become a CRS member for FREE ✅
Are you passionate about drug delivery research, but unable to cover the membership fee? Then check out our new Sponsored Membership Program👇
Several sponsors have already signed up. Apply today to profit from their generosity!
Pls retweet 🙏
Learn more about the CRS Sponsored Membership Program!
More info: 👉
Interested in becoming a sponsor for our Sponsored Membership Program? Click the link above to visit our website for more information and sponsorship details.
#crs
#deliveryscience
Enjoying day 1 of the
@CrsIndian
@CRSScience
LC meeting in Mumbai 🇮🇳. Over 400 highly interested and engaged attendees, excellent speakers, and several well-deserved recognitions, incl. the Lifetime Achievement Award for Prof. N. Udupa. Outstanding hospitality and organization👌
Comprehensive overview of nanoparticle imaging agents. With lots of details on their production, characterization, application and translation. Thanks
@DavidCormode
for magnificently leading this👌
Turning 50 today: Fabian Kiessling from
@RWTH
and
@UniklinikAachen
🎉🎂. Still the same looks as at age 40, at
@WMISWMIC
and
@ESMI_society
in Dublin 🏍🤘. Featured in Nature Communications and for a change fighting balloons instead of boxers 🥊😜
Had a great time in China last week 🇨🇳, visiting Nankai and Tianjin University, meeting old and new collaborators, attending ChinaNano 2023, and seeing some architectural masterpieces🏅
Check out the 40 Years Anniversary Issue of JCR /
@JCRnEDITORS
Quality and quantity (978 pages!) of authors and contributions are amazing👌
Highlights include a masterpiece by Prof. Jindrich Kopecek and orations by
@AnaBeloqui1
and
@GormleyLab
👉
Five great pieces of advice for writing a great scientific paper ✍️🧑💻🖼️ :
1 - Start with why.
2 - Keep it simple.
3 - Pictures are 1000 words.
4 - Details matter.
5 - Failure is key to success.
Check out the full text and details for free in
@JCRnEDITORS
👇
Warming up 😅 and chilling out 😎 for a big grant evaluation tomorrow. 5k run and 50k gravel ride along La Meuse. Lowest tides in ages. Included several strategic site visits to ensure a smooth and successful outcome 🤞🤞🤞
Targeting neutrophils in sepsis with RGD-modified liposomal dexamethasone 🦠
Excellent first paper by MD student Ritvik Mathur from
@UniklinikAachen
@RWTH
Work performed within the framework of our
@dfg_public
funded doctoral training network
#RTG2375
Very well-deserved recognition for Hamid Ghandehari
@H_Ghandehari
from
@PHCEUutah
for having done a tremendous job as editor-in-chief of Advanced Drug Delivery Reviews
@ADDReditors
. Check out and be part of the upcoming Emerging Voices 🎤 theme issue:
Brilliant perspective on
#MOF
biomedical applications by Alec Wang, Madeline Walden, Quim Pena et al. Concise, comprehensive and contemplative! Thanks
@wuttkescience
@Gassensmith
@Kiessling_F
for contributing.
Available open access in AFM👇
Important new work in
@AdvSciNews
. On mRNA transfection in tumor vs endothelial cells upon the use of microbubbles and ultrasound 🧬🔉🫧
#RTG2375
@dfg_public
I congratulate Junlin Chen and co-workers to a new paper that was just published in Advanced Science about the use of ultrasound and microbubbles for mRNA delivery to tumors: Chen J, et al. Adv Sci doi: 10.1002/advs.202306139. PMID: 38342634
Check it out and enjoy reading!
Check out this super-exciting virtual symposium coming up in September. Addressing in vitro diagnostics 🧪, robotic delivery 🦾, AI in drug development 💊, etc. Organized by Beate Bittner,
@MatooriSimon
and
@CRSScience
. Sponsored by
@Roche
. Pls retweet 🔄!
Interested in contributing to the best journal in drug delivery science? Learn about our new aims and directions. And feel free to reach out!
@JCRnEDITORS
@CRSScience
Time to say goodbye to Dr. Ilaria Biancacci
@ilaria93_ilaria
👩🏼🎓⚗️🔬. One of our favorite
#RTG2375
doctoral researchers. Many thanks for your commitment and engagement. Happy that we will be seeing you again very soon, at our
#ExMI
lab-out in Egmond aan Zee in May 🌊☀️🏝️
Dr. Ilaria Biancacci successfully defended her PhD thesis today
@RWTH
🎓. With flying colors 🎉. Flawless oral exam, 3 papers published and 2 in prep. In 3.5 years of RTG funding, generously provided by the DFG
@dfg_public
. Many congrats and enjoy your family holiday in 🇧🇪🇳🇱
Very much looking forward
#CRS2022
@CRSScience
, July 11-15, in Montreal. Awesome meeting, much fun, big impact, great topics, fantastic speakers, lovely people.
Part 2 of Xiangyang Bai’s PhD thesis 🎓, on covalently self-assembled nano-, micro- and macromaterials. In press at Advanced Materials. Thanks
@Yang_Shi_1
for conceiving and coordinating 👍, and
@DeLaporte_Lab
and
@wuttkescience
for collaborating 🙏.
Looking forward to the lecture, and to inspiring and fruitful interactions on how to connect chemistry and medicine across disciplines and countries 🇺🇦🇩🇪🇧🇪🇳🇱🇪🇺🌍
Important new paper, by Sarah Schraven et al, showing that different fluorescent dyes have different effects on polymeric nanocarrier biodistribution. Part of
#CRC1382
@dfg_public
. Another nice collaboration with
@MedPolymers_Prg
and
@IMC_Prague
🙏.
Very much looking forward
#CRS2022
@CRSScience
, July 11-15, in Montreal. Awesome meeting, much fun, big impact, great topics, fantastic speakers, lovely people.
Very nice first paper by doctoral researcher Mirjavad Moosavifar from
@UniklinikAachen
@RWTH
Engineering microbubbles with porous polymeric shells, thereby enhancing their ultrasound imaging and drug delivery capabilities 🔉🫧
Available open access at
What a great way to start
@2024Wbc
Breakfast with former
@JCRnEDITORS
colleague and closing plenary speaker Prof. Ick Chan Kwon (
@DoubleParr
)
Followed by a wonderful opening plenary lecture by Prof. Nicholas Peppas (
@NPeppas
)
#wbc2024
Much looking forward to the
@CRSScience
Spain and Portugal local chapter meeting. Impressive lineup of invited speakers, many young scientist talks, and lots of time for social interaction and networking. Thanks
@CRS_SPLC
for splendid organization👌
In Lisbon, Portugal 🇵🇹ready for the
@CRS_SPLC
SPLC-CRS 2024 meeting, the XVth meeting of this organization. The
@CRSScience
President
@twan_lammers
is also here. My plenary is in 3.5 hours.
The 2023 Journal Impact Factors have been published today 📚🔖.
#JIF
#impactfactor
#JCR
. Great to see the good performance and post-COVID consolidation of our most important nanomedicine, drug delivery, biomaterials and biomedical engineering journals.
@CRSScience
@SFBiomaterials
Just hours to go until the annual Journal Citation Reports release, when 21,500+ trusted journals will receive a Journal Impact Factor. Is your journal one of the 9,000+ receiving a
#JIF
for the first time? Join the conversation using
#JCR2023
and
#TrustedJournals
.
Two tightly packed days of delivery science are coming to an end. Congratulations to all presenters for their interesting contributions, and to the four awardees! And kudos to everyone who made this meeting possible!
See you in Bologna at
@CRSScience
or in Bern. Safe travels!
CRS PhD thesis award lectures at 6:30 PM in room 710 🏆. Many thanks to a great team of judges for going through 25 impressive theses. And thanks
@ElsevierConnect
and
@JCRnEDITORS
for supporting the award 👍.
@CRSScience
Many thanks to Dmitri Simberg and Tom Anchordoquy for putting together a great meeting on mechanisms, barriers and future directions in nanomedicine and targeted drug delivery. Outstanding lectures and lecturers, nice venue, lovely people, and valuable discussions 👍🏻🙏👌🏻
The 2024 Journal Citation Reports is coming soon! More than 21,800 trusted journals will receive a Journal Impact Factor. Join the conversation using
#JCR2024
and
#TrustedJournals
.
Paper
#2
in PhD year
#1
for Rui Zhang ✌️. Showcasing the energy, engagement and efficiency of JPI fellows 💪. Thanks Roger Molto Pallares for study design and supervision 👍.
@JPhysChem
@RWTH
@UniklinikAachen
Warming up 😅 and chilling out 😎 for a big grant evaluation tomorrow. 5k run and 50k gravel ride along La Meuse. Lowest tides in ages. Included several strategic site visits to ensure a smooth and successful outcome 🤞🤞🤞
Meet Your Plenary Speaker!
Register now: 👉
CRS is excited to have Luigi Naldini, M.D., Ph.D., as a plenary speaker at
#CRS2024
! Don't miss out on his plenary lecture. Click the link above today to join us in Italy!
#crs
#deliveryscience
Fantastic viewpoint by
@AthinaAnastasa1
in
@angew_chem
on “How to obtain an ERC starting grant” 🇪🇺. Valuable description of process and criteria, tips and tricks, and the importance of persistence 💪. Must-read for ambitious PhD students and postdocs 🔎.
@ERC_Research
@CRS_YSC
My perspective on what matters for an ERC Starting Grant: The art of failing and how persistence (and other factors) ultimately leads to success.
@angew_chem
@ERC_Research
Link:
Head of Research - Attractive leadership position available at Thermosome. Innovative biopharmaceutical company located in Munich and dedicated to demonstrating the potential of temperature-sensitive liposomes. Clinical trials in 2023.
@CRS_FG_NANO
@CRS_GermanChapt
@ESMI_SG_IGDD