Chris Clarke Profile
Chris Clarke

@tallcat78

Followers
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Following
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Tall, British-American, Scientist. Unashamed geek. Studying sphingolipids in cancer and making sudoku puzzles on the side. Thoughts, opinions are my own.

Stony Brook, NY
Joined November 2012
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@tallcat78
Chris Clarke
18 hours
@KoswasCrypto @cmonjussthetip @dietbrisk @whstancil Im all for IDC reform but this is not it
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@tallcat78
Chris Clarke
19 hours
RT @doristsao: I, and every scientist I've talked to, believe the end result of this devastating cut will be that Universities will simply…
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@tallcat78
Chris Clarke
19 hours
@cmonjussthetip @dietbrisk @whstancil The standard NIH research grant has a maximum request of $250K per year direct costs. There is an alternative that has a cap of $500K per year. For big ticket equipment, that would take an entire year or more of budget.
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@tallcat78
Chris Clarke
20 hours
Precisely this.
@mbeisen
Michael Eisen
2 days
The indiscriminate and ill-conceived slashing of indirects by the @NIH yesterday must be amended if want to restore America’s leadership role biomedical research. 15% simply isn’t enough for institutions to provide the basic infrastructure needed to run a successful lab. I say this as someone who has been and remains deeply critical of the NIH, its funding system and of the ways universities are structured and spend money. We would all benefit from a genuine reexamination of how and to what @NIH funds are allocated, and I remain optimistic that once the dust settles and new NIH leadership is in place that this is what will happen and this hack job by people who don’t understand or care about research will be forgotten. And I’m sorry but I can’t help but laugh at the people who are demanding a full-throated defense of the current indirect levels. Nearly every PI I’ve known for my entire career has complained about excessive indirect rates. This is mostly because, despite their importance, even most PIs haven’t bothered to actually understand them, and because they don’t FEEL that universities are actually spending the money to support their research. Whether they are or not nobody really knows because in the typically Byzantine maze of university budgets it’s often very hard to figure out. There are also lots of actual shenanigans that go on especially at places with the highest indirect rates to use funds to build out the institution and increase its power rather than to directly support funded research projects. And anyone who says administrative bloat at universities isn’t real and partially fueled by indirects is either blind or part of the bloat. So let’s get organized to have an actual constructive response to this firebomb. Scientists need to advocate for what is best for research - and we have to do it ourselves because the institutions that claim to represent us - universities and scientific societies in particular - have their own goals that often do not align with ours. We also have to remember that grants are not an entitlement. We are not owed anything. If we want to continue benefiting from the public support we have always enjoyed, we have to show the public and their representatives - even ones we might not always agree with - that we’re spending their money wisely.
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@tallcat78
Chris Clarke
20 hours
@cmonjussthetip @dietbrisk @whstancil Sure, I’ll blow two years of my grant budget on a mass spec. That’ll look good in my progress report “I didn’t do anything cause I spent it all on a mass spec”
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@tallcat78
Chris Clarke
20 hours
@cmonjussthetip @dietbrisk @whstancil Yeah, I need a mass spec for my work which costs about $500K. Pretty sure I won’t be able to buy that on a direct cost modular grant at $250K a year.
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@tallcat78
Chris Clarke
1 day
Yet where are the efficiency police to recoup some of the hundreds of billions of missing funds?
@The_Gilp
Gilp
2 days
The Pentagon budget in 2024 was $824 billion. These NIH “savings” of $4 billion amount to less than half of 1% of $824 billion. The Pentagon has failed six audits in a row.
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@tallcat78
Chris Clarke
1 day
@The_Gilp Yet it's still absolutely essential that they throw another few hundred billion at the DOD for....reasons.
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@tallcat78
Chris Clarke
1 day
Of course, all the money you are saving in indirect costs is going to be re-invested as direct costs for research grants, right? Right?
@NIH
NIH
3 days
Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead, what is known as “indirect costs.” Today, NIH lowered the maximum indirect cost rate research institutions can charge the government to 15%, above what many major foundations allow and much lower than the 60%+ that some institutions charge the government today. This change will save more than $4B a year effective immediately.
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@tallcat78
Chris Clarke
6 days
Highly encourage attending this conference. Should be a good one (and the registration is very competitive!)
@SL_Biology
Sphingolipid Biology
6 days
The early bird deadline may have passed but there is still plenty of time to register and submit abstracts for the 2025 FEBS/ICC! Come to historic Varna for sun, sea, and sphingolipid science!!
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@tallcat78
Chris Clarke
8 days
@SiskindLeah @BernieSanders Unfortunately the party in control of congress agrees with the lawsuits
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@tallcat78
Chris Clarke
16 days
RT @SL_Biology: @CaymanChemical have been stalwart supporters of the lipid community over the years and we are excited and grateful they ar…
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@tallcat78
Chris Clarke
18 days
RT @SL_Biology: 🚨🚨🚨 Only two days left to take advantage of lower registration for FEBS 2025 Sphingolipid Biology meeting! The final deadli…
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@tallcat78
Chris Clarke
22 days
RT @SL_Biology: 🚨🚨🚨 Important! At the request of attendees, we have extended the early bird deadline by one more week to Friday Jan 24th. T…
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@tallcat78
Chris Clarke
28 days
RT @SL_Biology: 🚨🚨🚨Attention all graduate students!! The deadline to apply for FEBS Travel Funds for the 2025 FEBS Special Meeting/13th ICC…
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@tallcat78
Chris Clarke
1 month
Moreover, the C16:C24-ceramide ratio - previously found to correlate with future adverse cardiac outcomes - was not as predictive in the anthracycline context, suggesting different mechanisms/pathways may be at play.
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