Nick Talbot
@talbotlabTSL
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Interested in plant pathology, fungal development, cell biology. I study a disease called rice blast. Executive Director, The Sainsbury Laboratory- Views my own
England, United Kingdom
Joined May 2010
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I don’t often tweet personal news, but I feel compelled to tell the story of my mother Rosita Talbot, who died recently and whose funeral was held this week. She had a remarkable life.
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The window through which a fungal spore blew and changed medicine forever. St. Mary’s Hospital Paddington tonight.
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I am grateful and honoured to receive an ERC Advanced Grant to study the role of septins during rice blast infections– SEPBLAST - exploring these remarkable morphogenetic proteins during plant disease 1/2
@TheSainsburyLab
#ERCAdG
📣 The results of the 2021 ERC Advanced Grants competition are out.
More than €624 million in funds were allocated to leading researchers in the European Union and
#HorizonEurope
associated countries.
All info 👉
🇪🇺
#EUfunded
#FrontierResearch
#ERCAdG
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My mother Rosita had a remarkable life. It is an honour to be her son.
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Passport stamped in Spain for first time since Franco died….I’ll never forgive the charlatans and liars who robbed me of my citizenship of Europe
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For any people confused about social distancing, who also know me (a small number I expect, but here goes). I am just over 2.0m tall. Separate yourselves in units of Nick T. - You're welcome.
#FlattenTheCurve
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Macho nonsense. We need self-reflective, self-critical scientists. I am much more worried about those that have never felt like imposters.
If you're a scientist and are constantly obsessed with "being an imposter", then either get over it, or get out of it, one of the two.
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I felt very sad queuing up to get my passport stamped in Germany. A big sense of loss for the freedoms taken away. I am a European above all else. Haven’t had my passport stamped in EU since I was about 10 yrs old!!
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Congratulations
@KamounLab
Recognised by award of the 2021 RKS Wood prize - BSPP - The British Society for Plant Pathology
@BS_PP
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We used a combination of cell biology, genetics, biochemistry & mathematical modelling to reveal that a sensor kinase controls turgor-driven plant infection by Magnaporthe.
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Rotem Sorek - Remarkable how many eukaryotic innate immune systems have evolved from bacterial systems for protection against phage (including cGAS-STING, TIR domains, viperins, gasdermins, SAMHD1) -
#EESImmunity
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As you are so happy to use a GM product to keep you healthy, isn't it time to reconsider Green Party opposition to GM technology that offers such potential for agriculture to cut GHG emissions & fossil fuel dependency, & become truly sustainable in a green economy??
So grateful to get my Astra Zeneca vaccination from
@BrightonCentre
today. Huge thanks to all the amazing staff & fab volunteers who make this happen every day - brilliantly efficient & so inspiring to see 🙏
When your time comes, do take it!
@nhs_scft
@SiobhanMelia
#Brighton
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GANTT charts for grant proposals - useful in the same way as a chocolate teapot.....
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Congratulations
@AliceEseola
for successfully defending her PhD today. Thanks to examiners Regine Kahmann and
@neil_gow
- PhD
#42
Halpin
#8
and last one from
@UniofExeter
- very proud supervisor.
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Congratulations to
@NeftalyCM
who successfully defended his PhD today. Here with proud supervisors, myself &
@Frank_Menke
and examiners
@dipietrolab
and Cyril Zipfel. PhD
#41
from my group!
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I am very honoured and hugely excited to be moving to
@TheSainsburyLab
- great times ahead!
NEWS - A new vision and Executive Director for The Sainsbury Laboratory -
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This is what credible, science literate and evidence-based political leadership looks like.
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The climate emergency is too urgent for the status quo in agriculture - we need innovative solutions that integrate advances in plant genetics with ecologically-sensitive organic production, to get off the chemical treadmill
Science can rescue farming. Relaxing gene editing rules should be the start | Nick Talbot
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Happy lab yesterday, staying safe & socially distancing- but always a team.
@TheSainsburyLab
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I am having to cut a substantial amount from an ongoing
@GCRF
@BBSRC
grant, which directly helps rice growers in sub-Saharan Africa to ensure food security- it is a massive breach of trust to cut ongoing projects of real impact
@UKRI_News
@beisgovuk
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Sad to hear of the death of Sydney Brenner. Great scientist, but to many of us who were grad students/postdocs in the 1990's he will always be 'Uncle Syd' from
@CurrentBiology
- Here's an example of his typical sage advice.
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This shows very clearly the importance of early containment of COVID-19 and why every organisation needs to take responsibility for the communities in which they are situated.
#FlattenTheCurve
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There was only one thing I could cook today wasn’t there? I was taught by the best.
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Congratulations Dr Diana Gomez de la Cruz!
@dianagdlc
on her successful PhD defence today. Great ambassador for
@MatthewMoscou
group and
@TheSainsburyLab
. Here with examiners
@Phil_Carella
and Thomas Kroj
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105 years ago today, my grandad fought in the Battle of the Somme. He lasted only 15 minutes until shot through the leg.He survived 12 hrs blood loss until a stretcher party picked him up. He lived until 1981 & believed strongly in the EC (now EU), because he despised war so much
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A call to arms for researchers to take up the exciting challenge of lichen biology in an Essay by
@thelichenlady
@metalichen
and I, part of
@CurrentBiology
special issue on Plant Interactions
@TheSainsburyLab
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Celebrating three
@biorxivpreprint
submissions (before the reviewers get hold of them!) and our recent paper of Magnaporthe protocols.
@Ryder_Lauren1
@angelyx97
@BozengTang
@CamilaMolinari3
@TheSainsburyLab
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A wonderful little book. Beautifully written, as you’d expect from the author. Synthesises so much biology in a clear and very simple way, and concludes with three principles that define life. Quite an achievement- definitely worth reading!
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I don’t think these ivory towers actually exist. Only politicians who haven’t been near a university in years have these views. Universities are fully engaged across sectors of society- much more so than most politicians in the Westminster bubble.
There is a bit of an ivory tower mentality in some universities when they should be building partnerships across all sectors of society, says former Homer Secretary Charles Clarke from
#ResearchEx
Find all our coverage of the summit here
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Peer-reviewed version of our phosphoproteomic analysis of Magnaporthe published today. We hope this resource, in which we identified conserved Pmk1-dependent phosphosites in 41 fungal species, will be valuable. 1/4
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This is how it starts
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A fine ending to a great week of science
@JohnInnesCentre
@TheSainsburyLab
annual symposium with our keynote speaker
@dolfweijers
- here with
@SaskiaHogenhout
@KamounLab
& Cyril Zipfel
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Congratulations to Barbara Valent
@ValentLab
for her well deserved election to the National Academy of Sciences USA
@theNASciences
#NAS157
- the whole rice blast research community salutes you, for all you have achieved.
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'Game-changing' is an often used term that is seldom deserved. But, this report from
@KamounLab
@JiorgosKourelis
@ClemMarchal
@Adeline_Harant
@adnroide
is TRULY game-changing for the control of plant disease 👇
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Exeter University launches trail-blazing maternity scheme: six months leave on full pay from first day at work
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I wrote this on the eve of the EU Referendum, worrying that the UK was about to make the biggest mistake of my lifetime. Well we will do that today. Nothing in the last 3 years has persuaded me otherwise. I will remain a European forever.
#IamEuropean
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Celebration with
@TheSainsburyLab
colleagues of a study led by
@Ryder_Lauren1
in collaboration with
@JorisSprakel
on mechanosensor analysis of appressorium membrane tension in the blast fungus
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Our collaboration with former lab member Min He and Xuewei Chen's laboratory, with contributions from
@Ryder_Lauren1
@BozengTang
@OsesMir
@angelyx97
and
@iris_eisermann
- Disrupting septin aggregation to control fungal pathogenesis
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Congratulations
@NeftalyCM
winner of the Excellence in Science Communication Award
@TheSainsburyLab
@JohnInnesCentre
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Met this guy today. He said he works in university management too.
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Interested in one of the most significant challenges in plant-microbe interactions? How does a lichen form from its constituent mycobiont and photobiont partners? How do morphogenetically complex lichen thalli develop?
@LeverhulmeTrust
-funded postdoctoral fellowship in my group.
A postdoctoral position is available with
@talbotlabTSL
to investigate the molecular basis of lichen symbiosis
#ScienceJobs
#Lichen
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A bright future ahead for
@TheSainsburyLab
as we secure funding with
@JohnInnesCentre
for new world-leading infrastructure– laboratories, glasshouses, CERs, advanced technology centre –in an innovative net zero carbon design. 1/3
📢NEWS - Incredible news as
@BBSRC
and
@UKRI_News
Infrastructure Fund confirms £317.7 million investment to secure the future of world-leading plant and microbial science
@TheSainsburyLab
@JohnInnesCentre
at the heart of the
@NorwichResearch
Park.
Read ➡️
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Found old school book from when I was very (very) young! I wrote an essay on food security. We looked at gains & losses to rice production- Getting a tractor was clearly important to me(!), but I was worried about lodging, and a disease called rice blast!
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To mark Remembrance Day, I want to tell you about a personal pilgrimage I took part in earlier this year. A thread below on the horrors of war.
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Well deserved recognition of
@KamounLab
for global impact of his leadership of
#openwheatblast
initiative to combat the devastating wheat blast disease.His inspiring speech spoke of his commitment to the global south & our shared humanity.
@joewinnz
#UEAIIAwards
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Please RT: New PhD opportunity in our group
@TheSainsburyLab
in the
@NRPBIODTP
- if you are interested in how turgor-sensing works in appressoria of the blast fungus, please apply before November 20th. For details see below 👇
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This is very cool - A TAL effector-like protein of an endofungal bacterium increases the stress tolerance and alters the transcriptome of the host
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Inspirational talk tonight from Jocelyn Bell Burnell at Gatsby Plant Science Network on the day she won the Breakthrough prize for discovery of radio pulsars & donated her $3 million prize to help women & under-represented groups into physics. Awesome & humbling to hear her story
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Just arriving into Innsbruck for
#ECFG16
- looking forward to catching up on all that's new!
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This is a serious challenge for the UK science community. If we are to attract the best talent to the UK we need to be removing obstacles, not creating them. The rhetoric about being a science superpower from
@SciTechgovuk
is not consistent with actual government policy
The UK is planning on massively increasing visa costs.
Currently a researcher looking at a 5-year Global Talent Visa, together with their partner and two children, needs to find £13.4k.
All up front. A big ask.
But that’s now slated to increase to…
**£20.9k**
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You've heard of plant blindness but what about fungus blindness?
"A Cure for 'Fungus Blindness'" my review of Entangled Life by
@MerlinSheldrake
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Very excited to announce the 2024 Cellular & Molecular Fungal Biology GRC organised by
@AnnaSelmecki
& myself with the theme of 'Fungal Communication' in all of its diverse forms. Vice-chairs
@DrValleyFever
&
@ElaineBignell
-Check out speakers & program using QR code below.
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Here, we release genome sequences of sixty Magnaporthe oryzae isolates from multiple host plant species to the community as a research resource
#OpenRiceBlast
#OpenWheatBlast
@vinniman
@KamounLab
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Great week at
#iCPP2023
with these great colleagues and friends. Thank you to the organisers. We all learned a lot and the conference highlighted the global significance of plant diseases and our role in helping ensure One Health
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Amazing that this is sent without any irony. A steam train from the last century, moving backwards, is about the most appropriate analogy for Brexit I’ve seen
Delighted to join the Brexit Express (
@BrexitE
) with
@DavidDavisMP
and others - there is a mood of cheery resolve...
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Reviewed version of our report of a forward genetic screen that identified a regulator of effector gene expression in Magnaporthe. It highlights how the expression of effector genes is highly orchestrated during infection-associated development.
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We may be witnessing the rapid evolution of backbones among a group of organisms that were hitherto acting as invertebrates.....two cases so far, perhaps more will appear?
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Congratulations to
@ClaraRHerrero
who successfully defended her PhD today to her examiners Mike Deeks
@Silystrngtheory
& Petra Boevink - a landmark for our group PhD
#40
.
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Paying homage to Darwin. Our research group day out at Natural History Museum, London
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A Christmas present to my daughter last year. I am hoping to get her something a bit more accurate this year....
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I am proud to have spent 11 years as an editor of New Phytologist. A journal that does so much for the whole plant sciences community. Happy Birthday!
'When the notion of starting a new botanical journal in this country was mooted, we were told by a certain distinguished botanist that it was not enough to shew there was room for a new periodical, necessity for its existence must be established.'
Happy 120th birthday to us! 🎂
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Very welcome news that we will be part of Horizon Europe. Vital to our science base and the futures of our young scientists in particular. Thanks to
@GeorgeFreemanMP
for his commitment to get this done. It is greatly appreciated.
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Happy joint 110th Birthday to
@jonathandgjones
and
@PeterVanesse
!
@TheSainsburyLab
@2blades
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We've published a set of protocols from our lab, expertly compiled by
@CamilaMolinari3
that we hope the community will find valuable. Free through open access.
A Basic Guide to the Growth and Manipulation of the Blast Fungus, Magnaporthe oryzae
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We show how the Pmk1 MAP kinase phosphorylates transcription factors Hox7 & Mst12 to control a hierarchical transcriptional network required for the major changes in gene expression necessary for infection cell development by Magnaporthe. A team effort led by
@OsesMir
OUT NOW: Appressorium-mediated plant infection by Magnaporthe oryzae is regulated by a Pmk1-dependent hierarchical transcriptional network
@talbotlabTSL
@TheSainsburyLab
@OsesMir
@UNavarra
Read it here:
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This included my
@ERC_Research
grant. Now we wait to see if the
@UKRI_News
guarantee, for which I’ve applied, materialises. Hard to believe that UK science is in such a position.
#BrexitShambles
On Thursday the European Research Council terminated 115 grants offered to UK based researchers as UK breaks international law over NI. Science super-power? Forget it. UK science minister in dispute with Treasury over post-Brexit funding via
@FT
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More Sunday morning plant pathology - Ramilaria rubella on Dock (Rumex sp). The red colour is caused by the rubellin phytotoxin (an anthraquinone).
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So sorry to hear that Nick Read has passed away. A fabulously talented fungal cell biologist, who contributed so much to the fungal biology community. Here he is at IMC9 in Edinburgh with Nancy Keller and John Taylor.
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It is a great pleasure to announce that
@wenboEffector
is moving to
@TheSainsburyLab
- we are all very excited that she will join our team!
We are pleased to announce that Professor Wenbo Ma
@wenboEffector
will be joining our team as Senior Group Leader in July 2020
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New work from our lab using CRISPR-Cas9-RNPs to carry out reproducible, efficient editing & co-editing of genes. We developed a novel counter-selection procedure that should be broadly applicable. Cas9 proved very toxic to M.o. when gene is introduced. RNPs are best way to go.
CRISPR-Cas9 ribonucleoprotein-mediated co-editing and counterselection in the rice blast fungus
#biorxiv_micrbio
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Celebrating
@BozengTang
and his Rgs1 paper
@TheSainsburyLab
keeping up the
#Halpin
Scholar tradition.
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Last night we celebrated the life of our colleague and friend Ken Haynes
@UofEHL
. The
@UniofExeter
honoured Ken by naming The Haynes Bridge in the
#LSI
in his memory. Thanks to
@jusher1979
for organising such a wonderful event.
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Check out our latest lichen paper. We have identified and characterised an alga, commonly associated with lichen symbioses, but which is not the primary photobiont. Fascinating study by
@metalichen
@thelichenlady
@angelyx97
👇
📑New Publication: Genomic analysis of Coccomyxa viridis, a common low‑abundance alga associated with lichen symbioses
@talbotlabTSL
@metalichen
@angelyx97
Full text 📷
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Lab celebration, bidding farewell to
@AliceEseola
who is off to St George’s in London to run their bio-imaging unit. Welcome to
@metalichen
&
@mattrwengler
& celebrating
@osesmir
being back with us for a visit!
@TheSainsburyLab
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This is a proper concession speech and real leadership.
John McCain’s concession speech from the 2008 election. Listen when the crowd “boos” Obama, he says stop and settles them. America, you are unrecognisable.
#ElectionResults2020
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Congratulations to
@NeftalyCM
JIF Prize winner for Scientific Research 2023
@TheSainsburyLab
@JohnInnesCentre
#proudsupervisor
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The RKS Wood Prize Lecture given by well deserved awardee
@KamounLab
under the halo
@BS_PP
#OPOF2021
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Here is
@Saunders_Lab
giving a great presentation on her
@DFID_UK
@BBSRC
@gatesfoundation
funded MARPLE programme for pathogen detection to
@BillGates
Lord Sainsbury and
@AlokSharma_RDG
NEWS:
#UKaid
partners with Gates Foundation to tackle global food insecurity
#GlobalGoals
@JohnInnesCentre
@CGIAR
@slcuplants
@BBSRC
@CIMMYT
@gatesfoundation
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Please RT: A fully-funded PhD project is available in my group
@TheSainsburyLab
- Investigating effector function in the rice blast fungus Magnaporthe oryzae - See also my collaborative PhD project with
@Frank_Menke
Details of both project are at link below.
👇TALBOT_S23DTP
UKRI-BBSRC Norwich Research Park Biosciences Doctoral Training Partnership projects for 2023 entry now advertised, deadline for application Monday 21st November 2022
@NRPBIODTP
@JohnInnesCentre
@EarlhamInst
@TheQuadram
@TheSainsburyLab
@uniofeastanglia
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Lockdown jobs- cleaning the pond. One of our resident newts!
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Our very own
@NeftalyCM
wins best poster prize
#ICPP2023
! Congratulations!
@TheSainsburyLab
.
@icpp2023
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Our new mini-review on septin-dependent invasive growth by Magnaporthe oryzae
@iris_eisermann
@TheSainsburyLab
-
Download PDF here
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.
@TheSainsburyLab
has today written officially to
@plant_pathology
and its parent publishers
@insightMedPub
for an explanation of why peer review evaluations of submissions to the journal were attributed to one of our research scientists without their knowledge or permission.
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