Sai Ma
@saima_lab
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Assistant Professor @MountSinai || Buenrostro Lab and Regev Lab Alumni || @Broad || @Harvard || single-cell omics || gene regulation
Joined July 2013
I am thrilled to announce that I will start my lab as an Assistant Professor in the Department of Genetics and Genomic Sciences @SinaiGenetics at Mount Sinai @IcahnMountSinai and a member of Icahn Genomics Institute @IcahnInstitute this fall!
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RT @wuzhengherbert: Thanks so much for the generous support. We are very excited about the new project! @saima_lab
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Glad to partner with Church Lab on finding a strategy to combat aging! Leveraging a human skin single cell atlas and we found a TF ATF3, an essential target in rejuvenating both epidermis and dermis through cell-cell interactions. Hope to say goodbye to aged skin :)
"Aged Skin? Hope Not Anymore!" Meet our technology from Church lab by experts from various disciplines @geochurch @saima_lab @rohitarorayyc @XaviRNA , "Human skin rejuvenation via mRNA," an innovative mRNA-based treatment to mitigate the effects of skin aging by targeting skin stem cells. Think of it as a little rebellion against aging, straight from the future! Say hello to youthful confidence and goodbye to concerns of skin aging.
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Super! Congratulations!
📢 Our latest paper is out in @CellCellPress! Led by the multi-talented @XinheZheng, we accelerated AAV-based gene delivery to 2 days & enabled in vivo CRISPR screens with single cell-level readout, a leap from existing capabilities 🤯 How does it work? (1/8)
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Huge congratulations!
GoT-ChA! I am thrilled to announce that our paper "Mapping Genotypes to Chromatin Accessibility Profiles in Single Cells" is now out in @Nature !! 👩🔬👨🔬🧬If you want to link somatic mutations to epigenetic changes directly in patient samples: 👇🧵
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Come join us and do some fun science!
Exciting joint postdoc position available!👇Join us & @saima_lab in applying spatial & multi-omics to study neural and genetic/epigenetic dynamics in cognition @SinaiBrain! Experimental background preferred. Competitive salary & subsidized housing provided. Retweets appreciated!
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So well deserved!
Jason Buenrostro (@JD_Buenrostro) is a cellular and molecular biologist and 2023 MacArthur Fellow investigating the mechanisms that regulate gene expression. #MacFellow Explore his work and all the 2023 MacArthur Fellows on our website!
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Check out this new single cell methylation approach from my PhD lab!
Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes #biorxiv_genomic
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@AllisonMBond @IcahnMountSinai @SinaiStemCell @SinaiBrain @NewPI_Slack Welcome to Sinai! We should chat sometime :). Our lab is one floor above yours
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RT @oana__ursu: We then asked how loss of mSWI/SNF affects chromatin accessibility using SHARE-seq in a wonderful collaboration with @saima…
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Our new preprint is out! A new computational tool to understand the chromatin-bind proteins using large-scale scATAC data
Single-cell ATAC-seq finds active regulatory elements across cell types, but its resolution can be limited. What if we could identify when and where proteins bind to chromatin? Introducing PRINT, a new single-cell footprinting tool from @JD_Buenrostro lab
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@NanYang_NY and my lab are on the hunt for a computational postdoc to join us @IcahnMountSinai to develop methods that integrate genomic/epigenomic, single-cell/spatial, and perturbation data in the context of neurological disorders. Email me directly!
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I am delighted to be invited to IICD! Fantastic people, science, and environment! Looking forward to more interactions.
Another great talk in our seminar series. Thank you to Sai Ma (@saima_lab) from @SinaiGenetics for sharing details about his research and career path with our trainees and researchers.
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Super excited to see this out and be part of the team!
Thrilled to share my primary PhD work: a Transcription Factor Atlas for understanding gene regulation and cell engineering @CellCellPress. We created a comprehensive TF ORF library and applied it to profile resulting expression changes. A thread 1/X
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RT @SBDRCatMtSinai: We are kicking off the new year with the first #FacultyHighlight of 2023. Dr. Sai Ma (@saima_lab) is a new addition to…
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