Ke Yuan
@keyuan1
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Senior Lecturer @GlasgowCS @UofGlasgow | Machine Learning & Computational Biology
Glasgow, Scotland
Joined August 2012
Big news: We just released PLM-interact, a tool for predicting protein-protein interactions, showing a 16-28% improvement over previous methods and even predicting mutation effects on interactions. Here’s the story behind this journey. 🧵👇
🚀 Our new preprint is out! We show that protein language models can predict protein-protein interactions by jointly encoding protein pairs, leading to significant improvements in PPI prediction.
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RT @gjmacintyre: One more day left to apply! Come join us in our effort to turn chemotherapy into a precision medicine.
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I’m truly stunned 🤯
Generating ~200 million parameters in just minutes! 🥳 Excited to share our work with @MTDovent , @heisejiasuo96 , and @YangYou1991: 'Recurrent Diffusion for Large-Scale Parameter Generation' (RPG for short). Example: Obtain customized models using prompts (see below). (🧵1/8)
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Very cool
✨Excited to share our work on “AI-powered virtual tissues from spatial proteomics for clinical diagnostics and biomedical discovery” (, building on our vision paper in @CellCellPress on multi-scale, multi-modal foundation models (.
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RT @gjmacintyre: We are hiring! Opportunity for a project manager to oversee all aspects of a multi-centre clinical research project to imp…
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RT @UofGMVLS: 🚀 MVLS #CollegeFutures PhD Programme! 🎓 Starting Oct 2025, we're offering 12 funded PhD studentships in: 🔬 Fundamentals of…
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RT @UladLitvin: Our new viral protein structure database 🦠 Explore protein structure, function & evolution 🧬 Dive in 🤿:
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RT @robertson_lab: new research & virus protein structure prediction resource - Viro3D - with @UladLitvin @SpyrosLytras Alex Jack @GroveLab…
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Very cool
What if we could look at a human tissue image🔬and quantify its biological age?🧬 And how could we get the same insights without collecting a tissue sample? In our new @biorxivpreprint, we create "tissue clocks" ⏳to do just that! 📝 #aging #tissue 🧵below
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RT @ara_anderson: If anyone is around today @CRUK_SI at noon I’ll be presenting some of recent work on @EvolTherapy focused on prostate can…
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RT @aipulserx: Can protein language models be adapted to accurately predict protein-protein interactions across different species and mutat…
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RT @BiologyAIDaily: PLM-interact: extending protein language models to predict protein-protein interactions 1. PLM-interact introduces a n…
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RT @craig_macdonald: Great to be involved in this work, applying information retrieval techniques to other types of language models - we sh…
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Huge congrats to @DanLiu_, our team (@Kieran12Lamb, @FranYoung5, @Adalberto_Cq, Alex Pancheva), and the supportive AI-in-bio community at @GlasgowCS, @CVRinfo, @CRUK_SI, @UofGCancerSci. Stay tuned for updates! 🧬 #AIinBiology #Bioinformatics #ProteinInteractions #AI
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