RT @GeorgeMonbiot: This is my farewell post. I am not deleting this account, as I don’t want to lose the archive, and I don’t want my name…

RT @howie_hua: Be on Santa's nice list by simply conveying what you mean mathematically clearly so we can stop having these PEMDAS argument…

@Psy_Fer_ @smllmp Mostly similarly burned in and by context of the values, but from time to time I need to type “man sam” to remind myself of the indexes of more obscure columns. (Needs a semi-well installed HTSlib with man pages included and perhaps MANPATH set if installed to a weird prefix.)

@camerongenomics @BonfieldJames @biomonika This sounds a lot like the functionality provided by my htsget-server-supporting branch from a long time ago, that is somewhere in the middle of my list of stuff to be dusted off someday:

RT @htanudisastro: 📢 New preprint alert: We’ve just published a deep dive into the role of tandem repeats (#TRs) in single-cell gene expres…

Python programmer: I'll stop spamming the logs by only logging every hundredth file processed. Ruff autocomplainer pre-commit hook: PLR2004 Magic value used in comparison, consider replacing `100` with a constant variable NO PERFECTLY OBVIOUS CODE FOR YOU, PUNY HUMAN!

@yvazirabad Some indicative numbers on some oldish unaligned short read data: gzipped FASTQ 1.7G, BAM 1.5G, CRAM 1.2G Sorted by minimiser with samtools sort ‑M: BAM 1.3G, CRAM 0.86G The same data but half the storage costs? It should be a no-brainer…

RT @WaltersLaura: This story on @NewsroomNZ Pro ($) is your periodic reminder that our PM writes all emails in blue comic sans https://t.c…

@strnr For about the same reason as TeX has a built-in \romannumeral primitive: the conversion is non-trivial, and they're useful for figure labelling, appendix numbering, etc.

RT @htslib: Release 1.21 of HTSlib, SAMtools, and BCFtools is now available from GitHub. See for links to tarballs…

Here we go again with overeager developers of niche operating systems with drive-by PRs, telling other projects how their code ought to work — without any knowledge of or care for the local reasons why that code might be the way it is… 🍿

@luka_culibrk I did wonder how you'd managed to avoid being exposed to hex notation 🤣 Always happy to have an excuse to publicise useful tidbits like `samtools flags` though!

RT @mmjukic: I don't know how they do it, but you can add inventing the perfect sports drink to the list of Japan's accomplishments. Uncann…

The “just use conda-forge & bioconda” answers to the current conda kerfuffle mostly gloss over the fact that those channels' artefact repository infrastructure appears to be owned and operated by Anaconda. Good to see that (and a path to an alternative) discussed in this posting.

RT @GrammarTable: I'm seeing mistakes on the internet. I hope this Grammar Table table helps.

RT @Psy_Fer_: Hot tip to avoid drama when benchmarking another author's tool: ask them the best way to run their tool. We have done this m…