Abby Holland
@holland_neuro
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NeuroTech Product Owner @IDUNTech . thinking about neurotech, longevity, et al - alum: biomedeng @queensu Clinical Neuro @UCL 🇨🇦
Zurich, Switzerland
Joined September 2019
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Hey folks!
I’ve recently gained some followers so thought I’d do a little intro!
I’m a PO in neurotech and like to tangent about the field, research, and things I find silly
I tend to comment on data science, wearables, and philosophy, and to summarize cool articles 😊
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So many BCI development discussions are around “how do we build a system with the BEST accuracy reliability etc”
This mindset can be a TRAP
It distracts from asking “what accuracy reliability etc is needed for X use case? How can I build that in a way that scales?”
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Lot of buzz going on about apples in ear electrodes patent
What a cool feeling to already have IP covered and to be on the market with
@IDUNTech
!
Unbelievably cool confirmation that we’re on the right track
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Reactions to the neuralink demo video are wild
So many are frustrated that laymen are celebrating without understanding context (eg braingate)
But neuralink has made it popular w good pr and marketing
This is GOOD for all of us!
Attention begets investment begets progress
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Always cool to see eeg hearables in nature!
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Dreem Sleep EEG just got FDA Clearance!
A big step for neurotech- brain analysis is getting more mobile, easy to use, and validated!
Link in comments 😊
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We are SO far from the ceiling with non invasive BCI
This is still a niche and hasn’t gone at all mass market!!
Who could’ve predicted that Apple Watches would be able to diagnose PD ?
More data = more (crazy) use cases
+ invasive is miles away from mass market
🧠💭 Are we nearing the ceiling for non-invasive BCI?
Is invasive BCI inevitable to reach the level of performance and integration required for an everyday device. Or are we going to see impactful products come up in the non-invasive space in the next ~5 years?
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wow, really feels like
#neurotech
is starting to hit its stride
new FDA reports are published weekly, trials are concluding successfully, and massive strides are being made towards safe tech that can improve lives
finally!
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An overview of neurotech aimed at investors!
Always fun to try and identify some of the inaccuracies and the stories they use to communicate some of the more complicated ideas
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“A lot of people are worried about AI, but I just didn’t share that view”
During a period of fear mongering, it was fascinating to hear Richard Sutton talk optimistically about the future of AI at
@creativedlab
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My first neurotech blog post had 3 Subs- all family members
Today Im publishing my second post w 140 subs…
The pressure deltas feeling pretty extreme !! Wish me luck
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i'll be in London this week (oct 10-17), and will be doing daytrips to cambridge and oxford as well
anyone want to meet for a coffee and talk
#BCIs
or
#Neurotech
?
BRIBE: I'll have the
@IDUNTech
in-ear EEG with me for demos
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another neurotech breakthrough designation!
this time a new treatment for Parkinson's
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yesterday the FDA cleared the first device for continuous glucose monitoring!
this is a HUGE step for wearables
+ an amazing step forward in how much an individual can understand their physiology
can't wait for these to be standard!
link 👇👇
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How important is a PhD for a career in neurotech?
this question is always a popular one, but good to discuss now among all the phd recent opportunities posted
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*lots* of drama in the neuro world these days
I am curious what big take downs of public figures in the space will do to the public perception of the field in general
Slowly getting more obsessed w the idea that neurotech needs more good pr asap
To be honest I was never a fan, but this makes him look way worse than I could have imagined. Long and upsetting read. It pisses me off this guy carries the banner for what passes as Neuroscience.
”Andrew Huberman's Mechanisms of Control”
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I had such a great time talking w Sophie about my journey into neurotech and where I see the field going!
Hopefully this can help some ppl looking to get into industry 👀
"I truly believe that consumer neurotech will help to democratise clinical neurotech"
@NeuroTechX
chapter lead Sophie Valentine spoke with
@IDUNTech
's
@holland_neuro
to discuss her journey in
#neurotech
, her view on diversity and lifting up
#WomenInSTEM
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SHOCKED that the foundation series has EEG as a major component of the plot
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@jasoncbenn
@bryan_johnson
Beggars in Spain is a great sci fi book based on this premise!
Would definitely recommend checking out
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Ok I literally posted 2 weeks ago about people starting to assume anyone using toefl/ ap English words is gpt
Already we see an example of this
is there any way of this going that doesn’t significantly reduce the quality of English??
Someone sent me a cold email proposing a novel project. Then I noticed it used the word "delve."
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We have 5 in ear eeg earbuds from
@IDUNTech
ready to offer for the developer and academia program!!
DM me if you want early access
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Been working on data engineering for managing wearables
This page lets you
- choose which data and timeline you care about
- directly compare any of your data (normalized)
- access each log individually (specifically requested)
- get insights from this data (pattern finding)
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In an effort to clean up my twitter feed I’m making a curated list for ppl/companies/orgs who often post interesting developments in neurotech
Think gossip, new releases, scientific developments
Feel free to request additions!
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We’ve worked so hard to make productivity metrics like cognitive workload quantifiable with the IDUN Guardian!
Im so happy we’re finally able to go share this project and some of our learnings 😊
In-Ear
#EEG
Earbuds can be used to measure Cognitive Workload. At
@IDUNTech
we're bringing brain-sensing capabilities to audio earbuds. Here
@holland_neuro
explains how we do it. Check out our white paper to learn more
#neuroscience
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A take away from the huberman discussions here:
It’s important to be super open about how much is unknown whenever we try and simplify topics for mass consumption
Eg highlighting if the brain was a mile we would’ve only walked 3 inches
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Excited to be taking about building digital therapeutics in a few weeks!
Come check it out 😊
The Digital Therapeutics Ecosystem: And Why It Matters, check out the event on
@LinkedIn
,
@holland_neuro
from
@IDUNTech
will be on the panel talking about
#wearables
,
#neurotech
and
#digitalhealth
.
#digitaltherapeutics
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I been obsessed w preventative health since studying clinical neuro
simple+trustworthy resources written for the average person are hard to find
I’ve been creating study notes to summarize some findings / key takeaways for myself
I may share some, maybe it’ll be useful?
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new post!!
talking about how integrated tech is becoming in our lives
and what that looks like for biosensors across the board
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Starting the year off right- with new content explaining cognitive load and how it’s quantified with EEG!
Stay tuned for the new podcasts from
@IDUNTech
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What is *the* killer application or use case of consumer BCIs that will become normalized over the next 10 years?
Curious to see what people will say across industry and academia
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hey hey i've been working a lot on a project to help automate and personalise health insights!
would love any and all feedback!
if you sign up, i'll send you free beta access on Testflgiht ;)
link below 👇
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wooow
i worked on a project which used DL on MRI signals to try and 'equalise' signals collected by different tesla precision and contexts
this helped predict brain-PAD biomarkers for diagnostic
imagine biomarker discovery if all mri recordings could be this res!!
11.7 Tesla MRI 🧠🫣 Can image 0.2 mm of brain tissue horizontally, in 1mm slices. Would take 2 hours in a conventional MRI. Images are wild >
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Australia approved MDMA and psilocybin prescription for PTSD and treatment-resistant depression!
worries remain about the rollout (ethics) and price (10k no subsidies)
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Increasing the tech that can read biosignals is the vital step to increase our understanding of medicine and improve its reach
We need different recording techniques with different focuses and specifications
This is possible w incremental and moonshot development attempts
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Patients who took donanemab showed a 37% lower risk of progression of the disease over a year and a half compared to patients who got the placebo
FDA committee votes that new Alzheimers Drug donanemab is EFFECTIVE & benefits outweigh risks
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My
#1
book reco for anyone in
#neurotech
,
#longevity
,
#sleep
is Beggars in Spain
What are other must reads in this space?
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there has been a lot of discussion in
#neurotech
this week about the 40Hz - AD relationship
basically- the idea is that 40Hz external stimulation can trigger peptide release and eventually promotes aB clearance
who is working on this in industry?
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To PhD or not to PhD?
The question that is keeping most people I know up at night simultaneously
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would anyone working in research that needs to track their subject's data be willing to hop on a user discovery call?
if you're a biohacker you can also be both researcher and subject in this case :)
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Nothing more inspiring to stick to my routines than needing to show people my health data anytime I demo wearable projects
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unsurprisingly, another study confirms that stress has lasting effects
this time, stress in adolescence is linked to changes in gene expression in the brain
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WOW it’s getting clearer why being a second time founder is appreciated by investors etc
There are so many routes one can take in launching projects/products !!!
So many factors to consider, this is why mentors matter
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@sharenarice
@Lourenco_MDA
@Kyle_Ireton
I like that!
And I guess hand in hand, it means we should at least have compassion for creators along the spectrum of what level of detail they expose / recommend as well
As you said, everyone’s just humans and we should try to keep that in mind
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if anyone wants a demo of our in-ear eeg
@IDUNTech
over teams, i'm happy to jump on a 20 min call!
got the idea after i didn't have time to meet w everyone who wanted demos in london!
booking link below :)
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Writing exam questions for the BCI uni course!
Any tips on how to make the questions really clear and comprehensive?
Unclear questions were always the most frustrating for me as a student
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a fun overview of at home eeg devices!
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Nothing bothers me more than ppl posting or talking about “science” where the conclusion is like
“And that is why this group of people is stupider than us”
Dangerous and LAZY
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i've been working on something!
tracking preventative, well-rounded health sucks right now - this has been aggravating me for years, so i decided to do something about it!
much more to come on this, but if you want to know more (or get a sneak peak) please reach out!
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An “enormous cell atlas” maps the brain at the cell level - identifying 3000 cell subtypes!
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Im making a personalized preventative health coach aimed at longevity, which uses passive wearable data!
If you use Apple / an Apple watch and want to try out something new DM me!
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After reviewing 185 studies of EEG and binaural beats, only 14 passed QA and their results were inconclusive 🧵
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hey all!
i'm thinking about posting more of my own thoughts/ impressions about BCIs, longevity, and preventative health
never fear- i'll still post *particularly* interesting articles with context / my impressions, but maybe just less often
any specific requests of things to add?
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I love the data collection to analysis simplified pipelines that are coming out!!
Seriously taking science to a new level
It’s so much easier to learn new outcomes, test new hypothesis, and get into the field when so much of work is augmented w tech!
Attention organelle enthusiasts!!
I am beyond thrilled to introduce Nellie: a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D/3D live-cell microscopy.
paper:
github:
🧵1/N
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A kidney from a genetically modified pig was just transplanted into a human!
This is a massive milestone, and signals a potential breakthrough for organ transplants
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working in wearables, using wearables, caring deeply about my health and the health of those around me, I've been consistently frustrated with the different options for data tracking and interpretation
so i built an alternative!
looking for feedback :)
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a neuroscientist's opinion on how mind/body work could be supported with scientific rigour and his musings on how this may have impacted his cancer diagnosis
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It’s been a big Silicon Valley week
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ultrasound is being used for addiction and alzheimers in trials!
very interesting potential in this tech
link 👇
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Ignoring that delve is a totally normal word to use-
If a founder leveraged AI to better explain their idea & be more efficient with reach outs…
aren’t those both good things?
Someone sent me a cold email proposing a novel project. Then I noticed it used the word "delve."
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SO many of the longevity people on here are just spouting pure pseudoscience
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Ok now they’re using a HAND-BASED BCI to control a ship
Um what
*very* ctrl labs
SHOCKED that the foundation series has EEG as a major component of the plot
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neuralink's first chip (telepathy) was implanted last week in their FDA-approved trial!
it aims to allow severely disabled people to control devices for movement control
for specifics on the study, check out their public overview:
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if you're bored and want to get inspired I highly recommend getting weirdly into sci fi
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it's always been bizarre to me that the default assumption is that other animals aren't conscious.
The only animals we can ask, humans, are conscious: why would we assume everything else isn't as well?
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women's health has always been lacking behind, largely stemming from limited investments into understanding and responding to women's problems
i predict the next 10 yrs will see a huge change in this, as people see a greater financial benefit from addressing women's issues
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@Andrew_Akbashev
@MarzbanNader
This is super useful! Would be awesome to have an application cheat sheet of big questions to ask during the interview process, both to the PI and to the other lab members
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Is it at the implant? Or is just being addicted to your phone enough? What about a pacemaker? What about a prosthetic?
Where *specifically* do you draw the line between human and cyborg?
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This book had a profound impact on how I see the world / politics, and has been an incredibly frightening backdrop to the changes in women’s rights and general discourse over the last 5-10yrs
I wish I could watch this show, but I couldn’t get past how real it could become.
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Do you think the researchers will name this entity Sophon?
I love it when ppl twist science fiction terms and leverage them in naming conventions
According to scientists at CERN, a mysterious entity was detected inside their particle collider. Physicists claim they have “captured and calculated the characteristics of a ‘ghost-like’ structure—an invisible entity that can alter the paths of particles…”
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prepping for my first (course) lecture next week!!
any tips?
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After a LOT of hard work, we’re finally ready to release our cognitive workload white paper!
Every wonder about using in ear eeg to quantify productivity? We’ve mapped out our first step!
Can’t wait to see what 2024 has in store for us at
@IDUNTech
Link 👇
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Social media can be used as many different things, and are often not designed to bring out the best of humanity
As builders we need to start producing social media to be used as a tool: apps etc that improve lives and are useful without the side effects (think
@Strava
)
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I’ll be in Cambridge Tuesday / Wednesday!
Anyone around for a tea?
Any good recs?
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@RCarhartHarris
Are these calibrated using subjective or objective metrics? Eg ratings vs EEG features as a factor of BMI
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very cool to see incubators / startup houses like
@_TheResidency
encouraging equity sharing- such a smart way to support winning as a team :)
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bilingualism shown to improve preterm babies' cognitive function!
this directly goes against current healthcare advice, and could directly change lives
i love research like this! challenge the conventional wisdom, and make sure to check the recent research yourself
(link 👇)
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Super crazy to be at CDL this week as a grad!
Any Toronto people around let me know if you want to try out our device!
CDL-Toronto Neuro grad
@IDUNTech
is building a database of brain activity with their built-in EEG earbud device using proprietary sensor material to measure & process brain signals with the same signal quality as the clinical gel EEG.
#CDLSuperSession2023
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This is completely wild
What a massive breakthrough
they took up the challenge of solving VR engineering and knocked it out of the park
intuitive, easy to use, tons of use cases already available, mass market appeal
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A good way to start the evening 😊
It’s incredible how incentivized I am by having a number to hit every day!
These health scores represent how my passive data compares to research based suggestions for preventative health and longevity
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If anyone else is interested !
here are some fave sci fi -y books (off the top of my head)
@focusfronting
Oookay!
I’m obsessed w neuro/bio tech so that reflects in my faves (sorry)
I loved
- beggars in Spain
- the lord of all things
- oryx and crake
- station 11
- 3 body problem
- dune
Next on my list is the expanse bc people won’t stop recommending it to me
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A lot of people have tried to pull of augmented glasses
This is the first time I’ve felt that they have a shot
Gen 2: w built in eeg?
These $META Smart Glasses look insane! They can essentially let you Google anything you are looking at.
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An incredibly impressive use of BCI!
Big congratulations to the whole
@neurosity
team- you guys are setting the bar with work like this!
Last year I could only boost my productivity by 30, maybe 40%.
Today, for the first time, I reached a 60% increase in focus. In 5 minutes.
It involves AI, a BCI, and a mobile app.
Here's how we pulled this off:
The Crown - an EEG device - uses AI-in-the-loop Neurofeedback to
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Wooow there you have it folks
First patient demo out of neuralink
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early detection is vital to solving dementia / AD in the future
these disorders build up over decades before symptoms arise
intervening earlier is necessary to halt/slow the decline before symptoms kick in
early biomarkers are going to be the key here
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Why does the us feel like a flashback in The Handmaids Tale right now
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a new study using fMRI shows that brain performance in older adults can improve by leveraging other regions of the brain that wouldn't normally be involved
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what an opportunity!!
guys this is one of the coolest neurotech companies rn
if you're a DS looking for something new check this out!
Are you a talented data scientist? Do you know a talented data scientist? Are either of you interested in neural interfaces / BCI?
💡Come work with us!💡
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An intensive overview on the
@neuralink
N1 chip!
As NL is one of the best-known companies, this deep dive is interesting for newbies or vets in the field
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Similarly- first time you build something 0-1, your perceived limits get blown away and you understand that you’re capable of creation in a way that cannot be explained
Makes it a lot easier to build again, and helps you dream a lot bigger for future projects
The first time you work really hard on something, in addition to the immediate benefit (whatever you were working for) you also learn that you're capable of working really hard. This makes it easier to be ambitious in all your future plans.
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medical vs consumer is always a bit of a debate in neurotech
the reality is some things are medical, some are not, and a lot are somewhere in between
many complications arise from this grey zone, including how user / patient journeys can be influenced
link 👇
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First day of remote only work tomorrow!
To mark the occasion I added a standing desk / stool option to my wfh setup
Any pro tips I should keep in mind?
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